A citation-based method for searching scientific literature

Andrew S Doré, Krzysztof Okrasa, Jayesh C Patel, Maria Serrano-Vega, Kirstie Bennett, Robert M Cooke, James C Errey, Ali Jazayeri, Samir Khan, Ben Tehan, Malcolm Weir, Giselle R Wiggin, Fiona H Marshall. Nature 2014
Times Cited: 289







List of co-cited articles
1234 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator.
Huixian Wu, Chong Wang, Karen J Gregory, Gye Won Han, Hyekyung P Cho, Yan Xia, Colleen M Niswender, Vsevolod Katritch, Jens Meiler, Vadim Cherezov,[...]. Science 2014
361
63

Structural insights into the activation of metabotropic glutamate receptors.
Antoine Koehl, Hongli Hu, Dan Feng, Bingfa Sun, Yan Zhang, Michael J Robertson, Matthew Chu, Tong Sun Kobilka, Toon Laeremans, Jan Steyaert,[...]. Nature 2019
132
55

Fragment and Structure-Based Drug Discovery for a Class C GPCR: Discovery of the mGlu5 Negative Allosteric Modulator HTL14242 (3-Chloro-5-[6-(5-fluoropyridin-2-yl)pyrimidin-4-yl]benzonitrile).
John A Christopher, Sarah J Aves, Kirstie A Bennett, Andrew S Doré, James C Errey, Ali Jazayeri, Fiona H Marshall, Krzysztof Okrasa, Maria J Serrano-Vega, Benjamin G Tehan,[...]. J Med Chem 2015
104
37

Structure-Based Optimization Strategies for G Protein-Coupled Receptor (GPCR) Allosteric Modulators: A Case Study from Analyses of New Metabotropic Glutamate Receptor 5 (mGlu5) X-ray Structures.
John A Christopher, Zoltán Orgován, Miles Congreve, Andrew S Doré, James C Errey, Fiona H Marshall, Jonathan S Mason, Krzysztof Okrasa, Prakash Rucktooa, Maria J Serrano-Vega,[...]. J Med Chem 2019
45
71

Major ligand-induced rearrangement of the heptahelical domain interface in a GPCR dimer.
Li Xue, Xavier Rovira, Pauline Scholler, Han Zhao, Jianfeng Liu, Jean-Philippe Pin, Philippe Rondard. Nat Chem Biol 2015
120
28

Organization and functions of mGlu and GABAB receptor complexes.
Jean-Philippe Pin, Bernhard Bettler. Nature 2016
126
27

Metabotropic glutamate receptors: physiology, pharmacology, and disease.
Colleen M Niswender, P Jeffrey Conn. Annu Rev Pharmacol Toxicol 2010
26

Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor.
N Kunishima, Y Shimada, Y Tsuji, T Sato, M Yamamoto, T Kumasaka, S Nakanishi, H Jingami, K Morikawa. Nature 2000
932
24

Crystal structure of the β2 adrenergic receptor-Gs protein complex.
Søren G F Rasmussen, Brian T DeVree, Yaozhong Zou, Andrew C Kruse, Ka Young Chung, Tong Sun Kobilka, Foon Sun Thian, Pil Seok Chae, Els Pardon, Diane Calinski,[...]. Nature 2011
23

Structures of the extracellular regions of the group II/III metabotropic glutamate receptors.
Takanori Muto, Daisuke Tsuchiya, Kosuke Morikawa, Hisato Jingami. Proc Natl Acad Sci U S A 2007
265
22

Molecular Switches of Allosteric Modulation of the Metabotropic Glutamate 2 Receptor.
Laura Pérez-Benito, Maarten L J Doornbos, Arnau Cordomí, Luc Peeters, Hilde Lavreysen, Leonardo Pardo, Gary Tresadern. Structure 2017
35
60

Structural mechanism of ligand activation in human GABA(B) receptor.
Yong Geng, Martin Bush, Lidia Mosyak, Feng Wang, Qing R Fan. Nature 2013
114
20

Practical Strategies and Concepts in GPCR Allosteric Modulator Discovery: Recent Advances with Metabotropic Glutamate Receptors.
Craig W Lindsley, Kyle A Emmitte, Corey R Hopkins, Thomas M Bridges, Karen J Gregory, Colleen M Niswender, P Jeffrey Conn. Chem Rev 2016
114
17

Identification of specific ligand-receptor interactions that govern binding and cooperativity of diverse modulators to a common metabotropic glutamate receptor 5 allosteric site.
Karen J Gregory, Elizabeth D Nguyen, Chrysa Malosh, Jeffrey L Mendenhall, Jessica Z Zic, Brittney S Bates, Meredith J Noetzel, Emma F Squire, Eric M Turner, Jerri M Rook,[...]. ACS Chem Neurosci 2014
39
43

Structures of metabotropic GABAB receptor.
Makaía M Papasergi-Scott, Michael J Robertson, Alpay B Seven, Ouliana Panova, Jesper M Mathiesen, Georgios Skiniotis. Nature 2020
34
50

Structural basis of the activation of a metabotropic GABA receptor.
Hamidreza Shaye, Andrii Ishchenko, Jordy Homing Lam, Gye Won Han, Li Xue, Philippe Rondard, Jean-Philippe Pin, Vsevolod Katritch, Cornelius Gati, Vadim Cherezov. Nature 2020
44
38

Structural mechanism of ligand activation in human calcium-sensing receptor.
Yong Geng, Lidia Mosyak, Igor Kurinov, Hao Zuo, Emmanuel Sturchler, Tat Cheung Cheng, Prakash Subramanyam, Alice P Brown, Sarah C Brennan, Hee-Chang Mun,[...]. Elife 2016
113
16

Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors.
Jean-Philippe Pin, Thierry Galvez, Laurent Prézeau. Pharmacol Ther 2003
449
16

Cryo-EM structures of inactive and active GABAB receptor.
Chunyou Mao, Cangsong Shen, Chuntao Li, Dan-Dan Shen, Chanjuan Xu, Shenglan Zhang, Rui Zhou, Qingya Shen, Li-Nan Chen, Zhinong Jiang,[...]. Cell Res 2020
38
42

Probing the metabotropic glutamate receptor 5 (mGlu₅) positive allosteric modulator (PAM) binding pocket: discovery of point mutations that engender a "molecular switch" in PAM pharmacology.
Karen J Gregory, Elizabeth D Nguyen, Sean D Reiff, Emma F Squire, Shaun R Stauffer, Craig W Lindsley, Jens Meiler, P Jeffrey Conn. Mol Pharmacol 2013
60
25


Trends in GPCR drug discovery: new agents, targets and indications.
Alexander S Hauser, Misty M Attwood, Mathias Rask-Andersen, Helgi B Schiöth, David E Gloriam. Nat Rev Drug Discov 2017
934
15

Distinct roles of metabotropic glutamate receptor dimerization in agonist activation and G-protein coupling.
Driss El Moustaine, Sébastien Granier, Etienne Doumazane, Pauline Scholler, Rita Rahmeh, Patrick Bron, Bernard Mouillac, Jean-Louis Banères, Philippe Rondard, Jean-Philippe Pin. Proc Natl Acad Sci U S A 2012
120
15

Generic GPCR residue numbers - aligning topology maps while minding the gaps.
Vignir Isberg, Chris de Graaf, Andrea Bortolato, Vadim Cherezov, Vsevolod Katritch, Fiona H Marshall, Stefan Mordalski, Jean-Philippe Pin, Raymond C Stevens, Gerrit Vriend,[...]. Trends Pharmacol Sci 2015
230
15

Mechanism of Assembly and Cooperativity of Homomeric and Heteromeric Metabotropic Glutamate Receptors.
Joshua Levitz, Chris Habrian, Shashank Bharill, Zhu Fu, Reza Vafabakhsh, Ehud Y Isacoff. Neuron 2016
89
16

Sequential inter- and intrasubunit rearrangements during activation of dimeric metabotropic glutamate receptor 1.
Veronika Hlavackova, Ulrike Zabel, Daniela Frankova, Julia Bätz, Carsten Hoffmann, Laurent Prezeau, Jean-Philippe Pin, Jaroslav Blahos, Martin J Lohse. Sci Signal 2012
59
23

Structure of human GABAB receptor in an inactive state.
Jinseo Park, Ziao Fu, Aurel Frangaj, Jonathan Liu, Lidia Mosyak, Tong Shen, Vesna N Slavkovich, Kimberly M Ray, Jaume Taura, Baohua Cao,[...]. Nature 2020
33
42

Selective Negative Allosteric Modulation Of Metabotropic Glutamate Receptors – A Structural Perspective of Ligands and Mutants.
Kasper Harpsøe, Vignir Isberg, Benjamin G Tehan, Dahlia Weiss, Angela Arsova, Fiona H Marshall, Hans Bräuner-Osborne, David E Gloriam. Sci Rep 2015
31
41

Heptahelical domain of metabotropic glutamate receptor 5 behaves like rhodopsin-like receptors.
Cyril Goudet, Florence Gaven, Julie Kniazeff, Claire Vol, Jiangfeng Liu, Martin Cohen-Gonsaud, Francine Acher, Laurent Prézeau, Jean Philippe Pin. Proc Natl Acad Sci U S A 2004
157
13

Closed state of both binding domains of homodimeric mGlu receptors is required for full activity.
Julie Kniazeff, Anne-Sophie Bessis, Damien Maurel, Hervé Ansanay, Laurent Prézeau, Jean-Philippe Pin. Nat Struct Mol Biol 2004
215
13

Activation and allosteric modulation of a muscarinic acetylcholine receptor.
Andrew C Kruse, Aaron M Ring, Aashish Manglik, Jianxin Hu, Kelly Hu, Katrin Eitel, Harald Hübner, Els Pardon, Celine Valant, Patrick M Sexton,[...]. Nature 2013
589
12

Structure of class B GPCR corticotropin-releasing factor receptor 1.
Kaspar Hollenstein, James Kean, Andrea Bortolato, Robert K Y Cheng, Andrew S Doré, Ali Jazayeri, Robert M Cooke, Malcolm Weir, Fiona H Marshall. Nature 2013
308
12

Interdomain movements in metabotropic glutamate receptor activation.
Siluo Huang, Jianhua Cao, Ming Jiang, Gilles Labesse, Jianfeng Liu, Jean-Philippe Pin, Philippe Rondard. Proc Natl Acad Sci U S A 2011
59
20

Investigating metabotropic glutamate receptor 5 allosteric modulator cooperativity, affinity, and agonism: enriching structure-function studies and structure-activity relationships.
Karen J Gregory, Meredith J Noetzel, Jerri M Rook, Paige N Vinson, Shaun R Stauffer, Alice L Rodriguez, Kyle A Emmitte, Ya Zhou, Aspen C Chun, Andrew S Felts,[...]. Mol Pharmacol 2012
67
17

A new approach to analyze cell surface protein complexes reveals specific heterodimeric metabotropic glutamate receptors.
Etienne Doumazane, Pauline Scholler, Jurriaan M Zwier, Eric Trinquet, Philippe Rondard, Jean-Philippe Pin. FASEB J 2011
198
12

Crystal structure of the µ-opioid receptor bound to a morphinan antagonist.
Aashish Manglik, Andrew C Kruse, Tong Sun Kobilka, Foon Sun Thian, Jesper M Mathiesen, Roger K Sunahara, Leonardo Pardo, William I Weis, Brian K Kobilka, Sébastien Granier. Nature 2012
918
12

Overlapping binding sites drive allosteric agonism and positive cooperativity in type 4 metabotropic glutamate receptors.
Xavier Rovira, Fanny Malhaire, Pauline Scholler, Jordi Rodrigo, Patricia Gonzalez-Bulnes, Amadeu Llebaria, Jean-Philippe Pin, Jesús Giraldo, Cyril Goudet. FASEB J 2015
42
28

Rearrangement of the transmembrane domain interfaces associated with the activation of a GPCR hetero-oligomer.
Li Xue, Qian Sun, Han Zhao, Xavier Rovira, Siyu Gai, Qianwen He, Jean-Philippe Pin, Jianfeng Liu, Philippe Rondard. Nat Commun 2019
26
46

Molecular mechanism of positive allosteric modulation of the metabotropic glutamate receptor 2 by JNJ-46281222.
Maarten L J Doornbos, Laura Pérez-Benito, Gary Tresadern, Thea Mulder-Krieger, Ilse Biesmans, Andrés A Trabanco, Jose María Cid, Hilde Lavreysen, Adriaan P IJzerman, Laura H Heitman. Br J Pharmacol 2016
30
36

Structural insights into G-protein-coupled receptor allostery.
David M Thal, Alisa Glukhova, Patrick M Sexton, Arthur Christopoulos. Nature 2018
135
11

Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer.
Junke Liu, Zongyong Zhang, David Moreno-Delgado, James Ar Dalton, Xavier Rovira, Ana Trapero, Cyril Goudet, Amadeu Llebaria, Jesús Giraldo, Qilin Yuan,[...]. Elife 2017
35
31

Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+.
Daisuke Tsuchiya, Naoki Kunishima, Narutoshi Kamiya, Hisato Jingami, Kosuke Morikawa. Proc Natl Acad Sci U S A 2002
279
11

Evidence for a single heptahelical domain being turned on upon activation of a dimeric GPCR.
Veronika Hlavackova, Cyril Goudet, Julie Kniazeff, Alice Zikova, Damien Maurel, Claire Vol, Johana Trojanova, Laurent Prézeau, Jean-Philippe Pin, Jaroslav Blahos. EMBO J 2005
119
11

UCSF Chimera--a visualization system for exploratory research and analysis.
Eric F Pettersen, Thomas D Goddard, Conrad C Huang, Gregory S Couch, Daniel M Greenblatt, Elaine C Meng, Thomas E Ferrin. J Comput Chem 2004
11

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor.
Vadim Cherezov, Daniel M Rosenbaum, Michael A Hanson, Søren G F Rasmussen, Foon Sun Thian, Tong Sun Kobilka, Hee-Jung Choi, Peter Kuhn, William I Weis, Brian K Kobilka,[...]. Science 2007
10

Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders.
P Jeffrey Conn, Arthur Christopoulos, Craig W Lindsley. Nat Rev Drug Discov 2009
759
10

Molecular determinants of positive allosteric modulation of the human metabotropic glutamate receptor 2.
A Farinha, H Lavreysen, L Peeters, B Russo, S Masure, A A Trabanco, J Cid, G Tresadern. Br J Pharmacol 2015
32
31

Illuminating the activation mechanisms and allosteric properties of metabotropic glutamate receptors.
Etienne Doumazane, Pauline Scholler, Ludovic Fabre, Jurriaan M Zwier, Eric Trinquet, Jean-Philippe Pin, Philippe Rondard. Proc Natl Acad Sci U S A 2013
72
13

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy.
Shawn Q Zheng, Eugene Palovcak, Jean-Paul Armache, Kliment A Verba, Yifan Cheng, David A Agard. Nat Methods 2017
10

Conformational dynamics of a class C G-protein-coupled receptor.
Reza Vafabakhsh, Joshua Levitz, Ehud Y Isacoff. Nature 2015
99
10


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.