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Times Cited: 1052
Times Cited
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Similarity
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Succinate is an inflammatory signal that induces IL-1β through HIF-1α.
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Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the warburg effect in LPS-activated macrophages.
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Gpr132 sensing of lactate mediates tumor-macrophage interplay to promote breast cancer metastasis.
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PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation.
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Tumor-derived lactate induces M2 macrophage polarization via the activation of the ERK/STAT3 signaling pathway in breast cancer.
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Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments.
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Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation.
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Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
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PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity.
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CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy.
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Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy.
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The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation.
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TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation.
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HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia.
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HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption.
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Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function.
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Tumor-derived lactate modifies antitumor immune response: effect on myeloid-derived suppressor cells and NK cells.
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Lactate Regulates Metabolic and Pro-inflammatory Circuits in Control of T Cell Migration and Effector Functions.
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Glutamine uptake and metabolism are coordinately regulated by ERK/MAPK during T lymphocyte activation.
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Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.