A citation-based method for searching scientific literature

Andrea Viale, Piergiorgio Pettazzoni, Costas A Lyssiotis, Haoqiang Ying, Nora Sánchez, Matteo Marchesini, Alessandro Carugo, Tessa Green, Sahil Seth, Virginia Giuliani, Maria Kost-Alimova, Florian Muller, Simona Colla, Luigi Nezi, Giannicola Genovese, Angela K Deem, Avnish Kapoor, Wantong Yao, Emanuela Brunetto, Ya'an Kang, Min Yuan, John M Asara, Y Alan Wang, Timothy P Heffernan, Alec C Kimmelman, Huamin Wang, Jason B Fleming, Lewis C Cantley, Ronald A DePinho, Giulio F Draetta. Nature 2014
Times Cited: 675







List of co-cited articles
1408 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


MYC/PGC-1α Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells.
Patricia Sancho, Emma Burgos-Ramos, Alejandra Tavera, Tony Bou Kheir, Petra Jagust, Matthieu Schoenhals, David Barneda, Katherine Sellers, Ramon Campos-Olivas, Osvaldo Graña,[...]. Cell Metab 2015
373
20

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
19

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway.
Jaekyoung Son, Costas A Lyssiotis, Haoqiang Ying, Xiaoxu Wang, Sujun Hua, Matteo Ligorio, Rushika M Perera, Cristina R Ferrone, Edouard Mullarky, Ng Shyh-Chang,[...]. Nature 2013
18

Understanding the Warburg effect: the metabolic requirements of cell proliferation.
Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
17

Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism.
Haoqiang Ying, Alec C Kimmelman, Costas A Lyssiotis, Sujun Hua, Gerald C Chu, Eliot Fletcher-Sananikone, Jason W Locasale, Jaekyoung Son, Hailei Zhang, Jonathan L Coloff,[...]. Cell 2012
17

BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells.
Eleni D Lagadinou, Alexander Sach, Kevin Callahan, Randall M Rossi, Sarah J Neering, Mohammad Minhajuddin, John M Ashton, Shanshan Pei, Valerie Grose, Kristen M O'Dwyer,[...]. Cell Stem Cell 2013
667
17

Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.
Cristovão M Sousa, Douglas E Biancur, Xiaoxu Wang, Christopher J Halbrook, Mara H Sherman, Li Zhang, Daniel Kremer, Rosa F Hwang, Agnes K Witkiewicz, Haoqiang Ying,[...]. Nature 2016
500
16

On the origin of cancer cells.
O WARBURG. Science 1956
16

An inhibitor of oxidative phosphorylation exploits cancer vulnerability.
Jennifer R Molina, Yuting Sun, Marina Protopopova, Sonal Gera, Madhavi Bandi, Christopher Bristow, Timothy McAfoos, Pietro Morlacchi, Jeffrey Ackroyd, Ahmed-Noor A Agip,[...]. Nat Med 2018
285
16

Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis.
William W Wheaton, Samuel E Weinberg, Robert B Hamanaka, Saul Soberanes, Lucas B Sullivan, Elena Anso, Andrea Glasauer, Eric Dufour, Gokhan M Mutlu, Gr Scott Budigner,[...]. Elife 2014
574
15

PGC1α expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress.
Francisca Vazquez, Ji-Hong Lim, Helen Chim, Kavita Bhalla, Geoff Girnun, Kerry Pierce, Clary B Clish, Scott R Granter, Hans R Widlund, Bruce M Spiegelman,[...]. Cancer Cell 2013
443
15

PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis.
Valerie S LeBleu, Joyce T O'Connell, Karina N Gonzalez Herrera, Harriet Wikman, Klaus Pantel, Marcia C Haigis, Fernanda Machado de Carvalho, Aline Damascena, Ludmilla Thome Domingos Chinen, Rafael M Rocha,[...]. Nat Cell Biol 2014
693
14

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells.
Cosimo Commisso, Shawn M Davidson, Rengin G Soydaner-Azeloglu, Seth J Parker, Jurre J Kamphorst, Sean Hackett, Elda Grabocka, Michel Nofal, Jeffrey A Drebin, Craig B Thompson,[...]. Nature 2013
852
13

Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells.
Michalina Janiszewska, Mario L Suvà, Nicolo Riggi, Riekelt H Houtkooper, Johan Auwerx, Virginie Clément-Schatlo, Ivan Radovanovic, Esther Rheinbay, Paolo Provero, Ivan Stamenkovic. Genes Dev 2012
248
12

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer.
Kirsten L Bryant, Clint A Stalnecker, Daniel Zeitouni, Jennifer E Klomp, Sen Peng, Andrey P Tikunov, Venugopal Gunda, Mariaelena Pierobon, Andrew M Waters, Samuel D George,[...]. Nat Med 2019
239
11

The Emerging Hallmarks of Cancer Metabolism.
Natalya N Pavlova, Craig B Thompson. Cell Metab 2016
11

MYC and MCL1 Cooperatively Promote Chemotherapy-Resistant Breast Cancer Stem Cells via Regulation of Mitochondrial Oxidative Phosphorylation.
Kyung-Min Lee, Jennifer M Giltnane, Justin M Balko, Luis J Schwarz, Angel L Guerrero-Zotano, Katherine E Hutchinson, Mellissa J Nixon, Mónica V Estrada, Violeta Sánchez, Melinda E Sanders,[...]. Cell Metab 2017
198
11

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity.
Frank Weinberg, Robert Hamanaka, William W Wheaton, Samuel Weinberg, Joy Joseph, Marcos Lopez, Balaraman Kalyanaraman, Gökhan M Mutlu, G R Scott Budinger, Navdeep S Chandel. Proc Natl Acad Sci U S A 2010
11

Overcoming intrinsic multidrug resistance in melanoma by blocking the mitochondrial respiratory chain of slow-cycling JARID1B(high) cells.
Alexander Roesch, Adina Vultur, Ivan Bogeski, Huan Wang, Katharina M Zimmermann, David Speicher, Christina Körbel, Matthias W Laschke, Phyllis A Gimotty, Stephan E Philipp,[...]. Cancer Cell 2013
400
11

Targeting mitochondrial oxidative phosphorylation eradicates therapy-resistant chronic myeloid leukemia stem cells.
Elodie M Kuntz, Pablo Baquero, Alison M Michie, Karen Dunn, Saverio Tardito, Tessa L Holyoake, G Vignir Helgason, Eyal Gottlieb. Nat Med 2017
199
11

Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism.
Thomas Farge, Estelle Saland, Fabienne de Toni, Nesrine Aroua, Mohsen Hosseini, Robin Perry, Claudie Bosc, Mayumi Sugita, Lucille Stuani, Marine Fraisse,[...]. Cancer Discov 2017
273
11

Metformin in patients with advanced pancreatic cancer: a double-blind, randomised, placebo-controlled phase 2 trial.
Sil Kordes, Michael N Pollak, Aeilko H Zwinderman, Ron A Mathôt, Mariëtte J Weterman, Aart Beeker, Cornelis J Punt, Dick J Richel, Johanna W Wilmink. Lancet Oncol 2015
225
10

Genomic analyses identify molecular subtypes of pancreatic cancer.
Peter Bailey, David K Chang, Katia Nones, Amber L Johns, Ann-Marie Patch, Marie-Claude Gingras, David K Miller, Angelika N Christ, Tim J C Bruxner, Michael C Quinn,[...]. Nature 2016
10

Targeting mitochondria metabolism for cancer therapy.
Samuel E Weinberg, Navdeep S Chandel. Nat Chem Biol 2015
709
10

Pancreatic cancers require autophagy for tumor growth.
Shenghong Yang, Xiaoxu Wang, Gianmarco Contino, Marc Liesa, Ergun Sahin, Haoqiang Ying, Alexandra Bause, Yinghua Li, Jayne M Stommel, Giacomo Dell'antonio,[...]. Genes Dev 2011
901
9

Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism.
Rushika M Perera, Svetlana Stoykova, Brandon N Nicolay, Kenneth N Ross, Julien Fitamant, Myriam Boukhali, Justine Lengrand, Vikram Deshpande, Martin K Selig, Cristina R Ferrone,[...]. Nature 2015
430
9

Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers.
Conan G Kinsey, Soledad A Camolotto, Amelie M Boespflug, Katrin P Guillen, Mona Foth, Amanda Truong, Sophia S Schuman, Jill E Shea, Michael T Seipp, Jeffrey T Yap,[...]. Nat Med 2019
238
9

Fundamentals of cancer metabolism.
Ralph J DeBerardinis, Navdeep S Chandel. Sci Adv 2016
9

Mitochondrial metabolism and cancer.
Paolo Ettore Porporato, Nicoletta Filigheddu, José Manuel Bravo-San Pedro, Guido Kroemer, Lorenzo Galluzzi. Cell Res 2018
357
9

Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma.
Richard A Moffitt, Raoud Marayati, Elizabeth L Flate, Keith E Volmar, S Gabriela Herrera Loeza, Katherine A Hoadley, Naim U Rashid, Lindsay A Williams, Samuel C Eaton, Alexander H Chung,[...]. Nat Genet 2015
747
9

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis.
Jessie Yanxiang Guo, Hsin-Yi Chen, Robin Mathew, Jing Fan, Anne M Strohecker, Gizem Karsli-Uzunbas, Jurre J Kamphorst, Guanghua Chen, Johanna M S Lemons, Vassiliki Karantza,[...]. Genes Dev 2011
847
9

Whole genomes redefine the mutational landscape of pancreatic cancer.
Nicola Waddell, Marina Pajic, Ann-Marie Patch, David K Chang, Karin S Kassahn, Peter Bailey, Amber L Johns, David Miller, Katia Nones, Kelly Quek,[...]. Nature 2015
8

Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine.
Daniel D Von Hoff, Thomas Ervin, Francis P Arena, E Gabriela Chiorean, Jeffrey Infante, Malcolm Moore, Thomas Seay, Sergei A Tjulandin, Wen Wee Ma, Mansoor N Saleh,[...]. N Engl J Med 2013
8

Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations.
Annan Yang, N V Rajeshkumar, Xiaoxu Wang, Shinichi Yabuuchi, Brian M Alexander, Gerald C Chu, Daniel D Von Hoff, Anirban Maitra, Alec C Kimmelman. Cancer Discov 2014
286
8


JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance.
Tianyi Wang, Johannes Francois Fahrmann, Heehyoung Lee, Yi-Jia Li, Satyendra C Tripathi, Chanyu Yue, Chunyan Zhang, Veronica Lifshitz, Jieun Song, Yuan Yuan,[...]. Cell Metab 2018
225
8

Metabolic signatures uncover distinct targets in molecular subsets of diffuse large B cell lymphoma.
Pilar Caro, Amar U Kishan, Erik Norberg, Illana A Stanley, Bjoern Chapuy, Scott B Ficarro, Klaudia Polak, Daniel Tondera, John Gounarides, Hong Yin,[...]. Cancer Cell 2012
282
8

Cancer statistics, 2019.
Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal. CA Cancer J Clin 2019
8

FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer.
Thierry Conroy, Françoise Desseigne, Marc Ychou, Olivier Bouché, Rosine Guimbaud, Yves Bécouarn, Antoine Adenis, Jean-Luc Raoul, Sophie Gourgou-Bourgade, Christelle de la Fouchardière,[...]. N Engl J Med 2011
8

Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA.
An S Tan, James W Baty, Lan-Feng Dong, Ayenachew Bezawork-Geleta, Berwini Endaya, Jacob Goodwin, Martina Bajzikova, Jaromira Kovarova, Martin Peterka, Bing Yan,[...]. Cell Metab 2015
385
8

Regulation of cancer cell metabolism.
Rob A Cairns, Isaac S Harris, Tak W Mak. Nat Rev Cancer 2011
8

Hallmarks of cancer stem cell metabolism.
Patricia Sancho, David Barneda, Christopher Heeschen. Br J Cancer 2016
215
8

Understanding the Intersections between Metabolism and Cancer Biology.
Matthew G Vander Heiden, Ralph J DeBerardinis. Cell 2017
831
8

Mitochondrial Metabolism as a Target for Cancer Therapy.
Karthik Vasan, Marie Werner, Navdeep S Chandel. Cell Metab 2020
65
12

Oxidative Phosphorylation as an Emerging Target in Cancer Therapy.
Thomas M Ashton, W Gillies McKenna, Leoni A Kunz-Schughart, Geoff S Higgins. Clin Cancer Res 2018
260
8

Safety and tolerability of the first-in-class agent CPI-613 in combination with modified FOLFIRINOX in patients with metastatic pancreatic cancer: a single-centre, open-label, dose-escalation, phase 1 trial.
Angela Alistar, Bonny B Morris, Rodwige Desnoyer, Heidi D Klepin, Keyanoosh Hosseinzadeh, Clancy Clark, Amy Cameron, John Leyendecker, Ralph D'Agostino, Umit Topaloglu,[...]. Lancet Oncol 2017
102
8

Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF.
Rizwan Haq, Jonathan Shoag, Pedro Andreu-Perez, Satoru Yokoyama, Hannah Edelman, Glenn C Rowe, Dennie T Frederick, Aeron D Hurley, Abhinav Nellore, Andrew L Kung,[...]. Cancer Cell 2013
514
8

Mitochondria and cancer.
Douglas C Wallace. Nat Rev Cancer 2012
7


The Warburg Effect: How Does it Benefit Cancer Cells?
Maria V Liberti, Jason W Locasale. Trends Biochem Sci 2016
7


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.