Alessio Lanna, Sian M Henson, David Escors, Arne N Akbar. Nat Immunol 2014
Times Cited: 173
Times Cited: 173
Times Cited
Times Co-cited
Similarity
A sestrin-dependent Erk-Jnk-p38 MAPK activation complex inhibits immunity during aging.
Alessio Lanna, Daniel C O Gomes, Bojana Muller-Durovic, Thomas McDonnell, David Escors, Derek W Gilroy, Jun Hee Lee, Michael Karin, Arne N Akbar. Nat Immunol 2017
Alessio Lanna, Daniel C O Gomes, Bojana Muller-Durovic, Thomas McDonnell, David Escors, Derek W Gilroy, Jun Hee Lee, Michael Karin, Arne N Akbar. Nat Immunol 2017
34
p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8⁺ T cells.
Sian M Henson, Alessio Lanna, Natalie E Riddell, Ornella Franzese, Richard Macaulay, Stephen J Griffiths, Daniel J Puleston, Alexander Scarth Watson, Anna Katharina Simon, Sharon A Tooze,[...]. J Clin Invest 2014
Sian M Henson, Alessio Lanna, Natalie E Riddell, Ornella Franzese, Richard Macaulay, Stephen J Griffiths, Daniel J Puleston, Alexander Scarth Watson, Anna Katharina Simon, Sharon A Tooze,[...]. J Clin Invest 2014
32
Senescence of T Lymphocytes: Implications for Enhancing Human Immunity.
Arne N Akbar, Sian M Henson, Alessio Lanna. Trends Immunol 2016
Arne N Akbar, Sian M Henson, Alessio Lanna. Trends Immunol 2016
31
Human CD8+ EMRA T cells display a senescence-associated secretory phenotype regulated by p38 MAPK.
Lauren A Callender, Elizabeth C Carroll, Robert W J Beal, Emma S Chambers, Sussan Nourshargh, Arne N Akbar, Sian M Henson. Aging Cell 2018
Lauren A Callender, Elizabeth C Carroll, Robert W J Beal, Emma S Chambers, Sussan Nourshargh, Arne N Akbar, Sian M Henson. Aging Cell 2018
27
Reversible senescence in human CD4+CD45RA+CD27- memory T cells.
Diletta Di Mitri, Rita I Azevedo, Sian M Henson, Valentina Libri, Natalie E Riddell, Richard Macaulay, David Kipling, Maria V D Soares, Luca Battistini, Arne N Akbar. J Immunol 2011
Diletta Di Mitri, Rita I Azevedo, Sian M Henson, Valentina Libri, Natalie E Riddell, Richard Macaulay, David Kipling, Maria V D Soares, Luca Battistini, Arne N Akbar. J Immunol 2011
22
Are senescence and exhaustion intertwined or unrelated processes that compromise immunity?
Arne N Akbar, Sian M Henson. Nat Rev Immunol 2011
Arne N Akbar, Sian M Henson. Nat Rev Immunol 2011
20
Regulatory T cells trigger effector T cell DNA damage and senescence caused by metabolic competition.
Xia Liu, Wei Mo, Jian Ye, Lingyun Li, Yanping Zhang, Eddy C Hsueh, Daniel F Hoft, Guangyong Peng. Nat Commun 2018
Xia Liu, Wei Mo, Jian Ye, Lingyun Li, Yanping Zhang, Eddy C Hsueh, Daniel F Hoft, Guangyong Peng. Nat Commun 2018
26
Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells.
Jason M Brenchley, Nitin J Karandikar, Michael R Betts, David R Ambrozak, Brenna J Hill, Laura E Crotty, Joseph P Casazza, Janaki Kuruppu, Stephen A Migueles, Mark Connors,[...]. Blood 2003
Jason M Brenchley, Nitin J Karandikar, Michael R Betts, David R Ambrozak, Brenna J Hill, Laura E Crotty, Joseph P Casazza, Janaki Kuruppu, Stephen A Migueles, Mark Connors,[...]. Blood 2003
17
Blockade of PD-1 or p38 MAP kinase signaling enhances senescent human CD8(+) T-cell proliferation by distinct pathways.
Sian M Henson, Richard Macaulay, Natalie E Riddell, Craig J Nunn, Arne N Akbar. Eur J Immunol 2015
Sian M Henson, Richard Macaulay, Natalie E Riddell, Craig J Nunn, Arne N Akbar. Eur J Immunol 2015
25
The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
15
CD28(-) T cells: their role in the age-associated decline of immune function.
Nan-Ping Weng, Arne N Akbar, Jorg Goronzy. Trends Immunol 2009
Nan-Ping Weng, Arne N Akbar, Jorg Goronzy. Trends Immunol 2009
15
15
Sestrins induce natural killer function in senescent-like CD8+ T cells.
Branca I Pereira, Roel P H De Maeyer, Luciana P Covre, Djamel Nehar-Belaid, Alessio Lanna, Sophie Ward, Radu Marches, Emma S Chambers, Daniel C O Gomes, Natalie E Riddell,[...]. Nat Immunol 2020
Branca I Pereira, Roel P H De Maeyer, Luciana P Covre, Djamel Nehar-Belaid, Alessio Lanna, Sophie Ward, Radu Marches, Emma S Chambers, Daniel C O Gomes, Natalie E Riddell,[...]. Nat Immunol 2020
23
The senescence-associated secretory phenotype: the dark side of tumor suppression.
Jean-Philippe Coppé, Pierre-Yves Desprez, Ana Krtolica, Judith Campisi. Annu Rev Pathol 2010
Jean-Philippe Coppé, Pierre-Yves Desprez, Ana Krtolica, Judith Campisi. Annu Rev Pathol 2010
13
p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype.
Adam Freund, Christopher K Patil, Judith Campisi. EMBO J 2011
Adam Freund, Christopher K Patil, Judith Campisi. EMBO J 2011
13
T cell anergy, exhaustion, senescence, and stemness in the tumor microenvironment.
Joel Crespo, Haoyu Sun, Theodore H Welling, Zhigang Tian, Weiping Zou. Curr Opin Immunol 2013
Joel Crespo, Haoyu Sun, Theodore H Welling, Zhigang Tian, Weiping Zou. Curr Opin Immunol 2013
13
Molecular and cellular insights into T cell exhaustion.
E John Wherry, Makoto Kurachi. Nat Rev Immunol 2015
E John Wherry, Makoto Kurachi. Nat Rev Immunol 2015
13
TLR8 signaling enhances tumor immunity by preventing tumor-induced T-cell senescence.
Jian Ye, Chunling Ma, Eddy C Hsueh, Jie Dou, Wei Mo, Shuai Liu, Bing Han, Yi Huang, Yanping Zhang, Mark A Varvares,[...]. EMBO Mol Med 2014
Jian Ye, Chunling Ma, Eddy C Hsueh, Jie Dou, Wei Mo, Shuai Liu, Bing Han, Yi Huang, Yanping Zhang, Mark A Varvares,[...]. EMBO Mol Med 2014
17
Tumor-derived γδ regulatory T cells suppress innate and adaptive immunity through the induction of immunosenescence.
Jian Ye, Chunling Ma, Eddy C Hsueh, Christopher S Eickhoff, Yanping Zhang, Mark A Varvares, Daniel F Hoft, Guangyong Peng. J Immunol 2013
Jian Ye, Chunling Ma, Eddy C Hsueh, Christopher S Eickhoff, Yanping Zhang, Mark A Varvares, Daniel F Hoft, Guangyong Peng. J Immunol 2013
12
The loss of telomerase activity in highly differentiated CD8+CD28-CD27- T cells is associated with decreased Akt (Ser473) phosphorylation.
Fiona J Plunkett, Ornella Franzese, Helene M Finney, Jean M Fletcher, Lavina L Belaramani, Mike Salmon, Inderjeet Dokal, David Webster, Alastair D G Lawson, Arne N Akbar. J Immunol 2007
Fiona J Plunkett, Ornella Franzese, Helene M Finney, Jean M Fletcher, Lavina L Belaramani, Mike Salmon, Inderjeet Dokal, David Webster, Alastair D G Lawson, Arne N Akbar. J Immunol 2007
12
12
Cellular senescence: when bad things happen to good cells.
Judith Campisi, Fabrizio d'Adda di Fagagna. Nat Rev Mol Cell Biol 2007
Judith Campisi, Fabrizio d'Adda di Fagagna. Nat Rev Mol Cell Biol 2007
12
Exhaustion and senescence: two crucial dysfunctional states of T cells in the tumor microenvironment.
Yangjing Zhao, Qixiang Shao, Guangyong Peng. Cell Mol Immunol 2020
Yangjing Zhao, Qixiang Shao, Guangyong Peng. Cell Mol Immunol 2020
15
Restoring function in exhausted CD8 T cells during chronic viral infection.
Daniel L Barber, E John Wherry, David Masopust, Baogong Zhu, James P Allison, Arlene H Sharpe, Gordon J Freeman, Rafi Ahmed. Nature 2006
Daniel L Barber, E John Wherry, David Masopust, Baogong Zhu, James P Allison, Arlene H Sharpe, Gordon J Freeman, Rafi Ahmed. Nature 2006
11
A biomarker that identifies senescent human cells in culture and in aging skin in vivo.
G P Dimri, X Lee, G Basile, M Acosta, G Scott, C Roskelley, E E Medrano, M Linskens, I Rubelj, O Pereira-Smith. Proc Natl Acad Sci U S A 1995
G P Dimri, X Lee, G Basile, M Acosta, G Scott, C Roskelley, E E Medrano, M Linskens, I Rubelj, O Pereira-Smith. Proc Natl Acad Sci U S A 1995
11
Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.
Francis Rodier, Jean-Philippe Coppé, Christopher K Patil, Wieteke A M Hoeijmakers, Denise P Muñoz, Saba R Raza, Adam Freund, Eric Campeau, Albert R Davalos, Judith Campisi. Nat Cell Biol 2009
Francis Rodier, Jean-Philippe Coppé, Christopher K Patil, Wieteke A M Hoeijmakers, Denise P Muñoz, Saba R Raza, Adam Freund, Eric Campeau, Albert R Davalos, Judith Campisi. Nat Cell Biol 2009
11
Human regulatory T cells induce T-lymphocyte senescence.
Jian Ye, Xingxu Huang, Eddy C Hsueh, Qunyuan Zhang, Chunling Ma, Yanping Zhang, Mark A Varvares, Daniel F Hoft, Guangyong Peng. Blood 2012
Jian Ye, Xingxu Huang, Eddy C Hsueh, Qunyuan Zhang, Chunling Ma, Yanping Zhang, Mark A Varvares, Daniel F Hoft, Guangyong Peng. Blood 2012
12
Age-Related Decline in Primary CD8+ T Cell Responses Is Associated with the Development of Senescence in Virtual Memory CD8+ T Cells.
Kylie M Quinn, Annette Fox, Kim L Harland, Brendan E Russ, Jasmine Li, Thi H O Nguyen, Liyen Loh, Moshe Olshanksy, Haroon Naeem, Kirill Tsyganov,[...]. Cell Rep 2018
Kylie M Quinn, Annette Fox, Kim L Harland, Brendan E Russ, Jasmine Li, Thi H O Nguyen, Liyen Loh, Moshe Olshanksy, Haroon Naeem, Kirill Tsyganov,[...]. Cell Rep 2018
11
The twilight of immunity: emerging concepts in aging of the immune system.
Janko Nikolich-Žugich. Nat Immunol 2018
Janko Nikolich-Žugich. Nat Immunol 2018
11
Rapid turnover of the CD8(+)CD28(-) T-cell subset of effector cells in the circulation of patients with head and neck cancer.
Takashi Tsukishiro, Albert D Donnenberg, Theresa L Whiteside. Cancer Immunol Immunother 2003
Takashi Tsukishiro, Albert D Donnenberg, Theresa L Whiteside. Cancer Immunol Immunother 2003
11
Cellular Senescence: Defining a Path Forward.
Vassilis Gorgoulis, Peter D Adams, Andrea Alimonti, Dorothy C Bennett, Oliver Bischof, Cleo Bishop, Judith Campisi, Manuel Collado, Konstantinos Evangelou, Gerardo Ferbeyre,[...]. Cell 2019
Vassilis Gorgoulis, Peter D Adams, Andrea Alimonti, Dorothy C Bennett, Oliver Bischof, Cleo Bishop, Judith Campisi, Manuel Collado, Konstantinos Evangelou, Gerardo Ferbeyre,[...]. Cell 2019
11
p53 isoforms regulate aging- and tumor-associated replicative senescence in T lymphocytes.
Abdul M Mondal, Izumi Horikawa, Sharon R Pine, Kaori Fujita, Katherine M Morgan, Elsa Vera, Sharlyn J Mazur, Ettore Appella, Borivoj Vojtesek, Maria A Blasco,[...]. J Clin Invest 2013
Abdul M Mondal, Izumi Horikawa, Sharon R Pine, Kaori Fujita, Katherine M Morgan, Elsa Vera, Sharlyn J Mazur, Ettore Appella, Borivoj Vojtesek, Maria A Blasco,[...]. J Clin Invest 2013
12
Senolytics improve physical function and increase lifespan in old age.
Ming Xu, Tamar Pirtskhalava, Joshua N Farr, Bettina M Weigand, Allyson K Palmer, Megan M Weivoda, Christina L Inman, Mikolaj B Ogrodnik, Christine M Hachfeld, Daniel G Fraser,[...]. Nat Med 2018
Ming Xu, Tamar Pirtskhalava, Joshua N Farr, Bettina M Weigand, Allyson K Palmer, Megan M Weivoda, Christina L Inman, Mikolaj B Ogrodnik, Christine M Hachfeld, Daniel G Fraser,[...]. Nat Med 2018
10
KLRG1 signaling induces defective Akt (ser473) phosphorylation and proliferative dysfunction of highly differentiated CD8+ T cells.
Sian M Henson, Ornella Franzese, Richard Macaulay, Valentina Libri, Rita I Azevedo, Sorena Kiani-Alikhan, Fiona J Plunkett, Joanne E Masters, Sarah Jackson, Stephen J Griffiths,[...]. Blood 2009
Sian M Henson, Ornella Franzese, Richard Macaulay, Valentina Libri, Rita I Azevedo, Sorena Kiani-Alikhan, Fiona J Plunkett, Joanne E Masters, Sarah Jackson, Stephen J Griffiths,[...]. Blood 2009
10
Inflamm-aging. An evolutionary perspective on immunosenescence.
C Franceschi, M Bonafè, S Valensin, F Olivieri, M De Luca, E Ottaviani, G De Benedictis. Ann N Y Acad Sci 2000
C Franceschi, M Bonafè, S Valensin, F Olivieri, M De Luca, E Ottaviani, G De Benedictis. Ann N Y Acad Sci 2000
10
Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan.
Darren J Baker, Bennett G Childs, Matej Durik, Melinde E Wijers, Cynthia J Sieben, Jian Zhong, Rachel A Saltness, Karthik B Jeganathan, Grace Casaclang Verzosa, Abdulmohammad Pezeshki,[...]. Nature 2016
Darren J Baker, Bennett G Childs, Matej Durik, Melinde E Wijers, Cynthia J Sieben, Jian Zhong, Rachel A Saltness, Karthik B Jeganathan, Grace Casaclang Verzosa, Abdulmohammad Pezeshki,[...]. Nature 2016
10
An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA.
Marco Demaria, Naoko Ohtani, Sameh A Youssef, Francis Rodier, Wendy Toussaint, James R Mitchell, Remi-Martin Laberge, Jan Vijg, Harry Van Steeg, Martijn E T Dollé,[...]. Dev Cell 2014
Marco Demaria, Naoko Ohtani, Sameh A Youssef, Francis Rodier, Wendy Toussaint, James R Mitchell, Remi-Martin Laberge, Jan Vijg, Harry Van Steeg, Martijn E T Dollé,[...]. Dev Cell 2014
10
Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases.
Claudio Franceschi, Judith Campisi. J Gerontol A Biol Sci Med Sci 2014
Claudio Franceschi, Judith Campisi. J Gerontol A Biol Sci Med Sci 2014
10
T cell senescence and CAR-T cell exhaustion in hematological malignancies.
Dimitri Kasakovski, Ling Xu, Yangqiu Li. J Hematol Oncol 2018
Dimitri Kasakovski, Ling Xu, Yangqiu Li. J Hematol Oncol 2018
10
Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor.
Jean-Philippe Coppé, Christopher K Patil, Francis Rodier, Yu Sun, Denise P Muñoz, Joshua Goldstein, Peter S Nelson, Pierre-Yves Desprez, Judith Campisi. PLoS Biol 2008
Jean-Philippe Coppé, Christopher K Patil, Francis Rodier, Yu Sun, Denise P Muñoz, Joshua Goldstein, Peter S Nelson, Pierre-Yves Desprez, Judith Campisi. PLoS Biol 2008
10
Molecular signature of CD8+ T cell exhaustion during chronic viral infection.
E John Wherry, Sang-Jun Ha, Susan M Kaech, W Nicholas Haining, Surojit Sarkar, Vandana Kalia, Shruti Subramaniam, Joseph N Blattman, Daniel L Barber, Rafi Ahmed. Immunity 2007
E John Wherry, Sang-Jun Ha, Susan M Kaech, W Nicholas Haining, Surojit Sarkar, Vandana Kalia, Shruti Subramaniam, Joseph N Blattman, Daniel L Barber, Rafi Ahmed. Immunity 2007
10
AMP-activated protein kinase activates p38 mitogen-activated protein kinase by increasing recruitment of p38 MAPK to TAB1 in the ischemic heart.
Ji Li, Edward J Miller, Jun Ninomiya-Tsuji, Raymond R Russell, Lawrence H Young. Circ Res 2005
Ji Li, Edward J Miller, Jun Ninomiya-Tsuji, Raymond R Russell, Lawrence H Young. Circ Res 2005
9
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders.
Darren J Baker, Tobias Wijshake, Tamar Tchkonia, Nathan K LeBrasseur, Bennett G Childs, Bart van de Sluis, James L Kirkland, Jan M van Deursen. Nature 2011
Darren J Baker, Tobias Wijshake, Tamar Tchkonia, Nathan K LeBrasseur, Bennett G Childs, Bart van de Sluis, James L Kirkland, Jan M van Deursen. Nature 2011
9
NKG2D ligands mediate immunosurveillance of senescent cells.
Adi Sagiv, Dominick G A Burton, Zhana Moshayev, Ezra Vadai, Felix Wensveen, Shifra Ben-Dor, Ofra Golani, Bojan Polic, Valery Krizhanovsky. Aging (Albany NY) 2016
Adi Sagiv, Dominick G A Burton, Zhana Moshayev, Ezra Vadai, Felix Wensveen, Shifra Ben-Dor, Ofra Golani, Bojan Polic, Valery Krizhanovsky. Aging (Albany NY) 2016
9
Lack of proliferative capacity of human effector and memory T cells expressing killer cell lectinlike receptor G1 (KLRG1).
David Voehringer, Marie Koschella, Hanspeter Pircher. Blood 2002
David Voehringer, Marie Koschella, Hanspeter Pircher. Blood 2002
9
Senescent cells evade immune clearance via HLA-E-mediated NK and CD8+ T cell inhibition.
Branca I Pereira, Oliver P Devine, Milica Vukmanovic-Stejic, Emma S Chambers, Priya Subramanian, Neil Patel, Alex Virasami, Neil J Sebire, Veronica Kinsler, Alexis Valdovinos,[...]. Nat Commun 2019
Branca I Pereira, Oliver P Devine, Milica Vukmanovic-Stejic, Emma S Chambers, Priya Subramanian, Neil Patel, Alex Virasami, Neil J Sebire, Veronica Kinsler, Alexis Valdovinos,[...]. Nat Commun 2019
9
The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.
Yi Zhu, Tamara Tchkonia, Tamar Pirtskhalava, Adam C Gower, Husheng Ding, Nino Giorgadze, Allyson K Palmer, Yuji Ikeno, Gene B Hubbard, Marc Lenburg,[...]. Aging Cell 2015
Yi Zhu, Tamara Tchkonia, Tamar Pirtskhalava, Adam C Gower, Husheng Ding, Nino Giorgadze, Allyson K Palmer, Yuji Ikeno, Gene B Hubbard, Marc Lenburg,[...]. Aging Cell 2015
9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.