A citation-based method for searching scientific literature


List of co-cited articles
825 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families.
E H Corder, A M Saunders, W J Strittmatter, D E Schmechel, P C Gaskell, G W Small, A D Roses, J L Haines, M A Pericak-Vance. Science 1993
27

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy.
Chia-Chen Liu, Chia-Chan Liu, Takahisa Kanekiyo, Huaxi Xu, Guojun Bu. Nat Rev Neurol 2013
25


Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.
Joseph M Castellano, Jungsu Kim, Floy R Stewart, Hong Jiang, Ronald B DeMattos, Bruce W Patterson, Anne M Fagan, John C Morris, Kwasi G Mawuenyega, Carlos Cruchaga,[...]. Sci Transl Med 2011
692
13

ApoE2, ApoE3, and ApoE4 Differentially Stimulate APP Transcription and Aβ Secretion.
Yu-Wen Alvin Huang, Bo Zhou, Marius Wernig, Thomas C Südhof. Cell 2017
249
13

Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector.
Chengzhong Wang, Ramsey Najm, Qin Xu, Dah-Eun Jeong, David Walker, Maureen E Balestra, Seo Yeon Yoon, Heidi Yuan, Gang Li, Zachary A Miller,[...]. Nat Med 2018
150
12

Apolipoprotein E: far more than a lipid transport protein.
R W Mahley, S C Rall. Annu Rev Genomics Hum Genet 2000
12

Profile and regulation of apolipoprotein E (ApoE) expression in the CNS in mice with targeting of green fluorescent protein gene to the ApoE locus.
Qin Xu, Aubrey Bernardo, David Walker, Tiffany Kanegawa, Robert W Mahley, Yadong Huang. J Neurosci 2006
288
10


Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium.
L A Farrer, L A Cupples, J L Haines, B Hyman, W A Kukull, R Mayeux, R H Myers, M A Pericak-Vance, N Risch, C M van Duijn. JAMA 1997
10

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease.
E H Corder, A M Saunders, N J Risch, W J Strittmatter, D E Schmechel, P C Gaskell, J B Rimmler, P A Locke, P M Conneally, K E Schmader. Nat Genet 1994
10

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.
Denise Harold, Richard Abraham, Paul Hollingworth, Rebecca Sims, Amy Gerrish, Marian L Hamshere, Jaspreet Singh Pahwa, Valentina Moskvina, Kimberley Dowzell, Amy Williams,[...]. Nat Genet 2009
10

Apolipoprotein E structure: insights into function.
Danny M Hatters, Clare A Peters-Libeu, Karl H Weisgraber. Trends Biochem Sci 2006
370
10

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.
Yang Shi, Kaoru Yamada, Shane Antony Liddelow, Scott T Smith, Lingzhi Zhao, Wenjie Luo, Richard M Tsai, Salvatore Spina, Lea T Grinberg, Julio C Rojas,[...]. Nature 2017
493
9

Resistance to autosomal dominant Alzheimer's disease in an APOE3 Christchurch homozygote: a case report.
Joseph F Arboleda-Velasquez, Francisco Lopera, Michael O'Hare, Santiago Delgado-Tirado, Claudia Marino, Natalia Chmielewska, Kahira L Saez-Torres, Dhanesh Amarnani, Aaron P Schultz, Reisa A Sperling,[...]. Nat Med 2019
157
9

Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
Brian W Kunkle, Benjamin Grenier-Boley, Rebecca Sims, Joshua C Bis, Vincent Damotte, Adam C Naj, Anne Boland, Maria Vronskaya, Sven J van der Lee, Alexandre Amlie-Wolf,[...]. Nat Genet 2019
838
9


Targeting of nonlipidated, aggregated apoE with antibodies inhibits amyloid accumulation.
Fan Liao, Aimin Li, Monica Xiong, Nga Bien-Ly, Hong Jiang, Yin Zhang, Mary Beth Finn, Rosa Hoyle, Jennifer Keyser, Katheryn B Lefton,[...]. J Clin Invest 2018
75
10



Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease.
D E Schmechel, A M Saunders, W J Strittmatter, B J Crain, C M Hulette, S H Joo, M A Pericak-Vance, D Goldgaber, A D Roses. Proc Natl Acad Sci U S A 1993
8

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
J C Lambert, C A Ibrahim-Verbaas, D Harold, A C Naj, R Sims, C Bellenguez, A L DeStafano, J C Bis, G W Beecham, B Grenier-Boley,[...]. Nat Genet 2013
8

Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study.
Eric M Reiman, Joseph F Arboleda-Velasquez, Yakeel T Quiroz, Matthew J Huentelman, Thomas G Beach, Richard J Caselli, Yinghua Chen, Yi Su, Amanda J Myers, John Hardy,[...]. Nat Commun 2020
114
8

The role of apolipoprotein E in Alzheimer's disease.
Jungsu Kim, Jacob M Basak, David M Holtzman. Neuron 2009
938
8

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease.
A M Saunders, W J Strittmatter, D Schmechel, P H George-Hyslop, M A Pericak-Vance, S H Joo, B L Rosi, J F Gusella, D R Crapper-MacLachlan, M J Alberts. Neurology 1993
8

Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice.
Walter J Brecht, Faith M Harris, Shengjun Chang, Ina Tesseur, Gui-Qiu Yu, Qin Xu, Jo Dee Fish, Tony Wyss-Coray, Manuel Buttini, Lennart Mucke,[...]. J Neurosci 2004
286
7

Human APOE isoform-dependent effects on brain beta-amyloid levels in PDAPP transgenic mice.
Kelly R Bales, Feng Liu, Su Wu, Suizhen Lin, Deanna Koger, Cynthia DeLong, Jeffrey C Hansen, Patrick M Sullivan, Steven M Paul. J Neurosci 2009
193
7

Topology of human apolipoprotein E3 uniquely regulates its diverse biological functions.
Jianglei Chen, Qianqian Li, Jianjun Wang. Proc Natl Acad Sci U S A 2011
144
7

ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE.
Suzanne E Wahrle, Hong Jiang, Maia Parsadanian, Justin Legleiter, Xianlin Han, John D Fryer, Tomasz Kowalewski, David M Holtzman. J Biol Chem 2004
315
7

ApoE and Aβ in Alzheimer's disease: accidental encounters or partners?
Takahisa Kanekiyo, Huaxi Xu, Guojun Bu. Neuron 2014
340
7

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease.
W J Strittmatter, K H Weisgraber, D Y Huang, L M Dong, G S Salvesen, M Pericak-Vance, D Schmechel, A M Saunders, D Goldgaber, A D Roses. Proc Natl Acad Sci U S A 1993
7

Apolipoprotein E, Receptors, and Modulation of Alzheimer's Disease.
Na Zhao, Chia-Chen Liu, Wenhui Qiao, Guojun Bu. Biol Psychiatry 2018
166
7

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.
W J Strittmatter, A M Saunders, D Schmechel, M Pericak-Vance, J Enghild, G S Salvesen, A D Roses. Proc Natl Acad Sci U S A 1993
7

A Quarter Century of APOE and Alzheimer's Disease: Progress to Date and the Path Forward.
Michaël E Belloy, Valerio Napolioni, Michael D Greicius. Neuron 2019
162
7

Effects of the absence of apolipoprotein e on lipoproteins, neurocognitive function, and retinal function.
Angel C Y Mak, Clive R Pullinger, Ling Fung Tang, Jinny S Wong, Rahul C Deo, Jean-Marc Schwarz, Alejandro Gugliucci, Irina Movsesyan, Brian Y Ishida, Catherine Chu,[...]. JAMA Neurol 2014
59
11

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.
Jean-Charles Lambert, Simon Heath, Gael Even, Dominique Campion, Kristel Sleegers, Mikko Hiltunen, Onofre Combarros, Diana Zelenika, Maria J Bullido, Béatrice Tavernier,[...]. Nat Genet 2009
7

Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies.
Yu Yamazaki, Na Zhao, Thomas R Caulfield, Chia-Chen Liu, Guojun Bu. Nat Rev Neurol 2019
303
7

Cholesterol metabolism and homeostasis in the brain.
Juan Zhang, Qiang Liu. Protein Cell 2015
254
6

Anti-apoE immunotherapy inhibits amyloid accumulation in a transgenic mouse model of Aβ amyloidosis.
Jungsu Kim, Adam E M Eltorai, Hong Jiang, Fan Liao, Philip B Verghese, Jaekwang Kim, Floy R Stewart, Jacob M Basak, David M Holtzman. J Exp Med 2012
90
6

Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons.
Y Huang, X Q Liu, T Wyss-Coray, W J Brecht, D A Sanan, R W Mahley. Proc Natl Acad Sci U S A 2001
287
6


Soluble apoE/Aβ complex: mechanism and therapeutic target for APOE4-induced AD risk.
Leon M Tai, Shipra Mehra, Varsha Shete, Steve Estus, G William Rebeck, Guojun Bu, Mary Jo LaDu. Mol Neurodegener 2014
87
6

ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions.
Philip B Verghese, Joseph M Castellano, Kanchan Garai, Yinong Wang, Hong Jiang, Aarti Shah, Guojun Bu, Carl Frieden, David M Holtzman. Proc Natl Acad Sci U S A 2013
314
6

Age, APOE and sex: Triad of risk of Alzheimer's disease.
Brandalyn C Riedel, Paul M Thompson, Roberta Diaz Brinton. J Steroid Biochem Mol Biol 2016
238
6

Apolipoprotein E, especially apolipoprotein E4, increases the oligomerization of amyloid β peptide.
Tadafumi Hashimoto, Alberto Serrano-Pozo, Yukiko Hori, Kenneth W Adams, Shuko Takeda, Adrian Olaf Banerji, Akinori Mitani, Daniel Joyner, Diana H Thyssen, Brian J Bacskai,[...]. J Neurosci 2012
168
6

Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.
K R Bales, T Verina, R C Dodel, Y Du, L Altstiel, M Bender, P Hyslop, E M Johnstone, S P Little, D J Cummins,[...]. Nat Genet 1997
646
6

Apolipoprotein E4 effects in Alzheimer's disease are mediated by synaptotoxic oligomeric amyloid-β.
Robert M Koffie, Tadafumi Hashimoto, Hwan-Ching Tai, Kevin R Kay, Alberto Serrano-Pozo, Daniel Joyner, Steven Hou, Katherine J Kopeikina, Matthew P Frosch, Virginia M Lee,[...]. Brain 2012
175
6

Therapeutic approaches targeting Apolipoprotein E function in Alzheimer's disease.
Tosha Williams, David R Borchelt, Paramita Chakrabarty. Mol Neurodegener 2020
44
13

Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice.
Faith M Harris, Walter J Brecht, Qin Xu, Ina Tesseur, Lisa Kekonius, Tony Wyss-Coray, Jo Dee Fish, Eliezer Masliah, Paul C Hopkins, Kimberly Scearce-Levie,[...]. Proc Natl Acad Sci U S A 2003
256
6

Apolipoprotein E in Alzheimer's disease: an update.
Jin-Tai Yu, Lan Tan, John Hardy. Annu Rev Neurosci 2014
266
6


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.