F M Menzies, M Garcia-Arencibia, S Imarisio, N C O'Sullivan, T Ricketts, B A Kent, M V Rao, W Lam, Z W Green-Thompson, R A Nixon, L M Saksida, T J Bussey, C J O'Kane, D C Rubinsztein. Cell Death Differ 2015
Times Cited: 71
Times Cited: 71
Times Cited
Times Co-cited
Similarity
Novel targets for Huntington's disease in an mTOR-independent autophagy pathway.
Andrea Williams, Sovan Sarkar, Paul Cuddon, Evangelia K Ttofi, Shinji Saiki, Farah H Siddiqi, Luca Jahreiss, Angeleen Fleming, Dean Pask, Paul Goldsmith,[...]. Nat Chem Biol 2008
Andrea Williams, Sovan Sarkar, Paul Cuddon, Evangelia K Ttofi, Shinji Saiki, Farah H Siddiqi, Luca Jahreiss, Angeleen Fleming, Dean Pask, Paul Goldsmith,[...]. Nat Chem Biol 2008
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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease.
Brinda Ravikumar, Coralie Vacher, Zdenek Berger, Janet E Davies, Shouqing Luo, Lourdes G Oroz, Francesco Scaravilli, Douglas F Easton, Rainer Duden, Cahir J O'Kane,[...]. Nat Genet 2004
Brinda Ravikumar, Coralie Vacher, Zdenek Berger, Janet E Davies, Shouqing Luo, Lourdes G Oroz, Francesco Scaravilli, Douglas F Easton, Rainer Duden, Cahir J O'Kane,[...]. Nat Genet 2004
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Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.
Sovan Sarkar, Janet E Davies, Zebo Huang, Alan Tunnacliffe, David C Rubinsztein. J Biol Chem 2007
Sovan Sarkar, Janet E Davies, Zebo Huang, Alan Tunnacliffe, David C Rubinsztein. J Biol Chem 2007
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Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease.
Claudia Rose, Fiona M Menzies, Maurizio Renna, Abraham Acevedo-Arozena, Silvia Corrochano, Oana Sadiq, Steve D Brown, David C Rubinsztein. Hum Mol Genet 2010
Claudia Rose, Fiona M Menzies, Maurizio Renna, Abraham Acevedo-Arozena, Silvia Corrochano, Oana Sadiq, Steve D Brown, David C Rubinsztein. Hum Mol Genet 2010
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Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis.
Shida Yousefi, Remo Perozzo, Inès Schmid, Andrew Ziemiecki, Thomas Schaffner, Leonardo Scapozza, Thomas Brunner, Hans-Uwe Simon. Nat Cell Biol 2006
Shida Yousefi, Remo Perozzo, Inès Schmid, Andrew Ziemiecki, Thomas Schaffner, Leonardo Scapozza, Thomas Brunner, Hans-Uwe Simon. Nat Cell Biol 2006
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Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations.
Ju-Hyun Lee, W Haung Yu, Asok Kumar, Sooyeon Lee, Panaiyur S Mohan, Corrinne M Peterhoff, Devin M Wolfe, Marta Martinez-Vicente, Ashish C Massey, Guy Sovak,[...]. Cell 2010
Ju-Hyun Lee, W Haung Yu, Asok Kumar, Sooyeon Lee, Panaiyur S Mohan, Corrinne M Peterhoff, Devin M Wolfe, Marta Martinez-Vicente, Ashish C Massey, Guy Sovak,[...]. Cell 2010
18
Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease.
Marta Martinez-Vicente, Zsolt Talloczy, Esther Wong, Guomei Tang, Hiroshi Koga, Susmita Kaushik, Rosa de Vries, Esperanza Arias, Spike Harris, David Sulzer,[...]. Nat Neurosci 2010
Marta Martinez-Vicente, Zsolt Talloczy, Esther Wong, Guomei Tang, Hiroshi Koga, Susmita Kaushik, Rosa de Vries, Esperanza Arias, Spike Harris, David Sulzer,[...]. Nat Neurosci 2010
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Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities.
Fiona M Menzies, Angeleen Fleming, Andrea Caricasole, Carla F Bento, Stephen P Andrews, Avraham Ashkenazi, Jens Füllgrabe, Anne Jackson, Maria Jimenez Sanchez, Cansu Karabiyik,[...]. Neuron 2017
Fiona M Menzies, Angeleen Fleming, Andrea Caricasole, Carla F Bento, Stephen P Andrews, Avraham Ashkenazi, Jens Füllgrabe, Anne Jackson, Maria Jimenez Sanchez, Cansu Karabiyik,[...]. Neuron 2017
18
Loss of autophagy in the central nervous system causes neurodegeneration in mice.
Masaaki Komatsu, Satoshi Waguri, Tomoki Chiba, Shigeo Murata, Jun-ichi Iwata, Isei Tanida, Takashi Ueno, Masato Koike, Yasuo Uchiyama, Eiki Kominami,[...]. Nature 2006
Masaaki Komatsu, Satoshi Waguri, Tomoki Chiba, Shigeo Murata, Jun-ichi Iwata, Isei Tanida, Takashi Ueno, Masato Koike, Yasuo Uchiyama, Eiki Kominami,[...]. Nature 2006
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TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity.
Mickael Decressac, Bengt Mattsson, Pia Weikop, Martin Lundblad, Johan Jakobsson, Anders Björklund. Proc Natl Acad Sci U S A 2013
Mickael Decressac, Bengt Mattsson, Pia Weikop, Martin Lundblad, Johan Jakobsson, Anders Björklund. Proc Natl Acad Sci U S A 2013
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Huntingtin functions as a scaffold for selective macroautophagy.
Yan-Ning Rui, Zhen Xu, Bindi Patel, Zhihua Chen, Dongsheng Chen, Antonio Tito, Gabriela David, Yamin Sun, Erin F Stimming, Hugo J Bellen,[...]. Nat Cell Biol 2015
Yan-Ning Rui, Zhen Xu, Bindi Patel, Zhihua Chen, Dongsheng Chen, Antonio Tito, Gabriela David, Yamin Sun, Erin F Stimming, Hugo J Bellen,[...]. Nat Cell Biol 2015
16
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice.
Taichi Hara, Kenji Nakamura, Makoto Matsui, Akitsugu Yamamoto, Yohko Nakahara, Rika Suzuki-Migishima, Minesuke Yokoyama, Kenji Mishima, Ichiro Saito, Hideyuki Okano,[...]. Nature 2006
Taichi Hara, Kenji Nakamura, Makoto Matsui, Akitsugu Yamamoto, Yohko Nakahara, Rika Suzuki-Migishima, Minesuke Yokoyama, Kenji Mishima, Ichiro Saito, Hideyuki Okano,[...]. Nature 2006
16
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy.
Serhiy Pankiv, Terje Høyvarde Clausen, Trond Lamark, Andreas Brech, Jack-Ansgar Bruun, Heidi Outzen, Aud Øvervatn, Geir Bjørkøy, Terje Johansen. J Biol Chem 2007
Serhiy Pankiv, Terje Høyvarde Clausen, Trond Lamark, Andreas Brech, Jack-Ansgar Bruun, Heidi Outzen, Aud Øvervatn, Geir Bjørkøy, Terje Johansen. J Biol Chem 2007
15
Lithium induces autophagy by inhibiting inositol monophosphatase.
Sovan Sarkar, R Andres Floto, Zdenek Berger, Sara Imarisio, Axelle Cordenier, Matthieu Pasco, Lynnette J Cook, David C Rubinsztein. J Cell Biol 2005
Sovan Sarkar, R Andres Floto, Zdenek Berger, Sara Imarisio, Axelle Cordenier, Matthieu Pasco, Lynnette J Cook, David C Rubinsztein. J Cell Biol 2005
15
Trehalose alleviates polyglutamine-mediated pathology in a mouse model of Huntington disease.
Motomasa Tanaka, Yoko Machida, Sanyong Niu, Tetsurou Ikeda, Nihar R Jana, Hiroshi Doi, Masaru Kurosawa, Munenori Nekooki, Nobuyuki Nukina. Nat Med 2004
Motomasa Tanaka, Yoko Machida, Sanyong Niu, Tetsurou Ikeda, Nihar R Jana, Hiroshi Doi, Masaru Kurosawa, Munenori Nekooki, Nobuyuki Nukina. Nat Med 2004
15
Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy.
Brinda Ravikumar, Rainer Duden, David C Rubinsztein. Hum Mol Genet 2002
Brinda Ravikumar, Rainer Duden, David C Rubinsztein. Hum Mol Genet 2002
14
Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease.
Patricia Spilman, Natalia Podlutskaya, Matthew J Hart, Jayanta Debnath, Olivia Gorostiza, Dale Bredesen, Arlan Richardson, Randy Strong, Veronica Galvan. PLoS One 2010
Patricia Spilman, Natalia Podlutskaya, Matthew J Hart, Jayanta Debnath, Olivia Gorostiza, Dale Bredesen, Arlan Richardson, Randy Strong, Veronica Galvan. PLoS One 2010
14
Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons.
Karen Castillo, Melissa Nassif, Vicente Valenzuela, Fabiola Rojas, Soledad Matus, Gabriela Mercado, Felipe A Court, Brigitte van Zundert, Claudio Hetz. Autophagy 2013
Karen Castillo, Melissa Nassif, Vicente Valenzuela, Fabiola Rojas, Soledad Matus, Gabriela Mercado, Felipe A Court, Brigitte van Zundert, Claudio Hetz. Autophagy 2013
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The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation.
Yvette C Wong, Erika L F Holzbaur. J Neurosci 2014
Yvette C Wong, Erika L F Holzbaur. J Neurosci 2014
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Overexpression of the calpain-specific inhibitor calpastatin reduces human alpha-Synuclein processing, aggregation and synaptic impairment in [A30P]αSyn transgenic mice.
Meike Diepenbroek, Nicolas Casadei, Hakan Esmer, Takaomi C Saido, Jiro Takano, Philipp J Kahle, Ralph A Nixon, Mala V Rao, Ronald Melki, Laura Pieri,[...]. Hum Mol Genet 2014
Meike Diepenbroek, Nicolas Casadei, Hakan Esmer, Takaomi C Saido, Jiro Takano, Philipp J Kahle, Ralph A Nixon, Mala V Rao, Ronald Melki, Laura Pieri,[...]. Hum Mol Genet 2014
14
14
Rapamycin alleviates toxicity of different aggregate-prone proteins.
Zdenek Berger, Brinda Ravikumar, Fiona M Menzies, Lourdes Garcia Oroz, Benjamin R Underwood, Menelas N Pangalos, Ina Schmitt, Ullrich Wullner, Bernd O Evert, Cahir J O'Kane,[...]. Hum Mol Genet 2006
Zdenek Berger, Brinda Ravikumar, Fiona M Menzies, Lourdes Garcia Oroz, Benjamin R Underwood, Menelas N Pangalos, Ina Schmitt, Ullrich Wullner, Bernd O Evert, Cahir J O'Kane,[...]. Hum Mol Genet 2006
14
Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease.
Barry Boland, Asok Kumar, Sooyeon Lee, Frances M Platt, Jerzy Wegiel, W Haung Yu, Ralph A Nixon. J Neurosci 2008
Barry Boland, Asok Kumar, Sooyeon Lee, Frances M Platt, Jerzy Wegiel, W Haung Yu, Ralph A Nixon. J Neurosci 2008
14
Calpain Inhibition Is Protective in Machado-Joseph Disease Zebrafish Due to Induction of Autophagy.
Maxinne Watchon, Kristy C Yuan, Nick Mackovski, Adam J Svahn, Nicholas J Cole, Claire Goldsbury, Silke Rinkwitz, Thomas S Becker, Garth A Nicholson, Angela S Laird. J Neurosci 2017
Maxinne Watchon, Kristy C Yuan, Nick Mackovski, Adam J Svahn, Nicholas J Cole, Claire Goldsbury, Silke Rinkwitz, Thomas S Becker, Garth A Nicholson, Angela S Laird. J Neurosci 2017
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Stimulation of autophagy reduces neurodegeneration in a mouse model of human tauopathy.
Véronique Schaeffer, Isabelle Lavenir, Sefika Ozcelik, Markus Tolnay, David T Winkler, Michel Goedert. Brain 2012
Véronique Schaeffer, Isabelle Lavenir, Sefika Ozcelik, Markus Tolnay, David T Winkler, Michel Goedert. Brain 2012
12
TFEB links autophagy to lysosomal biogenesis.
Carmine Settembre, Chiara Di Malta, Vinicia Assunta Polito, Moises Garcia Arencibia, Francesco Vetrini, Serkan Erdin, Serpil Uckac Erdin, Tuong Huynh, Diego Medina, Pasqualina Colella,[...]. Science 2011
Carmine Settembre, Chiara Di Malta, Vinicia Assunta Polito, Moises Garcia Arencibia, Francesco Vetrini, Serkan Erdin, Serpil Uckac Erdin, Tuong Huynh, Diego Medina, Pasqualina Colella,[...]. Science 2011
12
Autophagy induction reduces mutant ataxin-3 levels and toxicity in a mouse model of spinocerebellar ataxia type 3.
Fiona M Menzies, Jeannette Huebener, Maurizio Renna, Michael Bonin, Olaf Riess, David C Rubinsztein. Brain 2010
Fiona M Menzies, Jeannette Huebener, Maurizio Renna, Michael Bonin, Olaf Riess, David C Rubinsztein. Brain 2010
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Rhes, a striatal-selective protein implicated in Huntington disease, binds beclin-1 and activates autophagy.
Robert G Mealer, Alexandra J Murray, Neelam Shahani, Srinivasa Subramaniam, Solomon H Snyder. J Biol Chem 2014
Robert G Mealer, Alexandra J Murray, Neelam Shahani, Srinivasa Subramaniam, Solomon H Snyder. J Biol Chem 2014
12
Specific calpain inhibition by calpastatin prevents tauopathy and neurodegeneration and restores normal lifespan in tau P301L mice.
Mala V Rao, Mary Kate McBrayer, Jabbar Campbell, Asok Kumar, Audrey Hashim, Henry Sershen, Philip H Stavrides, Masuo Ohno, Michael Hutton, Ralph A Nixon. J Neurosci 2014
Mala V Rao, Mary Kate McBrayer, Jabbar Campbell, Asok Kumar, Audrey Hashim, Henry Sershen, Philip H Stavrides, Masuo Ohno, Michael Hutton, Ralph A Nixon. J Neurosci 2014
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Alpha-Synuclein is degraded by both autophagy and the proteasome.
Julie L Webb, Brinda Ravikumar, Jane Atkins, Jeremy N Skepper, David C Rubinsztein. J Biol Chem 2003
Julie L Webb, Brinda Ravikumar, Jane Atkins, Jeremy N Skepper, David C Rubinsztein. J Biol Chem 2003
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The calpain system.
Darrell E Goll, ValeryY F Thompson, Hongqi Li, Wei Wei, Jinyang Cong. Physiol Rev 2003
Darrell E Goll, ValeryY F Thompson, Hongqi Li, Wei Wei, Jinyang Cong. Physiol Rev 2003
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A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin.
Sovan Sarkar, Gauri Krishna, Sara Imarisio, Shinji Saiki, Cahir J O'Kane, David C Rubinsztein. Hum Mol Genet 2008
Sovan Sarkar, Gauri Krishna, Sara Imarisio, Shinji Saiki, Cahir J O'Kane, David C Rubinsztein. Hum Mol Genet 2008
12
Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases.
Brian Spencer, Rewati Potkar, Margarita Trejo, Edward Rockenstein, Christina Patrick, Ryan Gindi, Anthony Adame, Tony Wyss-Coray, Eliezer Masliah. J Neurosci 2009
Brian Spencer, Rewati Potkar, Margarita Trejo, Edward Rockenstein, Christina Patrick, Ryan Gindi, Anthony Adame, Tony Wyss-Coray, Eliezer Masliah. J Neurosci 2009
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AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.
Joungmok Kim, Mondira Kundu, Benoit Viollet, Kun-Liang Guan. Nat Cell Biol 2011
Joungmok Kim, Mondira Kundu, Benoit Viollet, Kun-Liang Guan. Nat Cell Biol 2011
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Trehalose ameliorates dopaminergic and tau pathology in parkin deleted/tau overexpressing mice through autophagy activation.
Jose A Rodríguez-Navarro, Laura Rodríguez, María J Casarejos, Rosa M Solano, Ana Gómez, Juan Perucho, Ana María Cuervo, Justo García de Yébenes, María A Mena. Neurobiol Dis 2010
Jose A Rodríguez-Navarro, Laura Rodríguez, María J Casarejos, Rosa M Solano, Ana Gómez, Juan Perucho, Ana María Cuervo, Justo García de Yébenes, María A Mena. Neurobiol Dis 2010
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Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy.
Ana Maria Cuervo, Leonidas Stefanis, Ross Fredenburg, Peter T Lansbury, David Sulzer. Science 2004
Ana Maria Cuervo, Leonidas Stefanis, Ross Fredenburg, Peter T Lansbury, David Sulzer. Science 2004
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Aβ secretion and plaque formation depend on autophagy.
Per Nilsson, Krishnapriya Loganathan, Misaki Sekiguchi, Yukio Matsuba, Kelvin Hui, Satoshi Tsubuki, Motomasa Tanaka, Nobuhisa Iwata, Takashi Saito, Takaomi C Saido. Cell Rep 2013
Per Nilsson, Krishnapriya Loganathan, Misaki Sekiguchi, Yukio Matsuba, Kelvin Hui, Satoshi Tsubuki, Motomasa Tanaka, Nobuhisa Iwata, Takashi Saito, Takaomi C Saido. Cell Rep 2013
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Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
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Calpain inhibition is sufficient to suppress aggregation of polyglutamine-expanded ataxin-3.
Annette Haacke, F Ulrich Hartl, Peter Breuer. J Biol Chem 2007
Annette Haacke, F Ulrich Hartl, Peter Breuer. J Biol Chem 2007
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Calpain-mediated ataxin-3 cleavage in the molecular pathogenesis of spinocerebellar ataxia type 3 (SCA3).
Jeannette Hübener, Jonasz Jeremiasz Weber, Claudia Richter, Lisa Honold, Andreas Weiss, Fabronia Murad, Peter Breuer, Ullrich Wüllner, Peter Bellstedt, Francois Paquet-Durand,[...]. Hum Mol Genet 2013
Jeannette Hübener, Jonasz Jeremiasz Weber, Claudia Richter, Lisa Honold, Andreas Weiss, Fabronia Murad, Peter Breuer, Ullrich Wüllner, Peter Bellstedt, Francois Paquet-Durand,[...]. Hum Mol Genet 2013
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Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado-Joseph disease.
Ana T Simões, Nélio Gonçalves, Arnulf Koeppen, Nicole Déglon, Sebastian Kügler, Carlos Bandeira Duarte, Luís Pereira de Almeida. Brain 2012
Ana T Simões, Nélio Gonçalves, Arnulf Koeppen, Nicole Déglon, Sebastian Kügler, Carlos Bandeira Duarte, Luís Pereira de Almeida. Brain 2012
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Overexpression of the autophagic beclin-1 protein clears mutant ataxin-3 and alleviates Machado-Joseph disease.
Isabel Nascimento-Ferreira, Tiago Santos-Ferreira, Lígia Sousa-Ferreira, Gwennaëlle Auregan, Isabel Onofre, Sandro Alves, Noëlle Dufour, Veronica F Colomer Gould, Arnulf Koeppen, Nicole Déglon,[...]. Brain 2011
Isabel Nascimento-Ferreira, Tiago Santos-Ferreira, Lígia Sousa-Ferreira, Gwennaëlle Auregan, Isabel Onofre, Sandro Alves, Noëlle Dufour, Veronica F Colomer Gould, Arnulf Koeppen, Nicole Déglon,[...]. Brain 2011
11
Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis.
Brian J DeBosch, Monique R Heitmeier, Allyson L Mayer, Cassandra B Higgins, Jan R Crowley, Thomas E Kraft, Maggie Chi, Elizabeth P Newberry, Zhouji Chen, Brian N Finck,[...]. Sci Signal 2016
Brian J DeBosch, Monique R Heitmeier, Allyson L Mayer, Cassandra B Higgins, Jan R Crowley, Thomas E Kraft, Maggie Chi, Elizabeth P Newberry, Zhouji Chen, Brian N Finck,[...]. Sci Signal 2016
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Potential function for the Huntingtin protein as a scaffold for selective autophagy.
Joseph Ochaba, Tamás Lukacsovich, George Csikos, Shuqiu Zheng, Julia Margulis, Lisa Salazar, Kai Mao, Alice L Lau, Sylvia Y Yeung, Sandrine Humbert,[...]. Proc Natl Acad Sci U S A 2014
Joseph Ochaba, Tamás Lukacsovich, George Csikos, Shuqiu Zheng, Julia Margulis, Lisa Salazar, Kai Mao, Alice L Lau, Sylvia Y Yeung, Sandrine Humbert,[...]. Proc Natl Acad Sci U S A 2014
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Polyglutamine tracts regulate beclin 1-dependent autophagy.
Avraham Ashkenazi, Carla F Bento, Thomas Ricketts, Mariella Vicinanza, Farah Siddiqi, Mariana Pavel, Ferdinando Squitieri, Maarten C Hardenberg, Sara Imarisio, Fiona M Menzies,[...]. Nature 2017
Avraham Ashkenazi, Carla F Bento, Thomas Ricketts, Mariella Vicinanza, Farah Siddiqi, Mariana Pavel, Ferdinando Squitieri, Maarten C Hardenberg, Sara Imarisio, Fiona M Menzies,[...]. Nature 2017
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Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
9
The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy.
Maria Filimonenko, Pauline Isakson, Kim D Finley, Monique Anderson, Hyun Jeong, Thomas J Melia, Bryan J Bartlett, Katherine M Myers, Hanne C G Birkeland, Trond Lamark,[...]. Mol Cell 2010
Maria Filimonenko, Pauline Isakson, Kim D Finley, Monique Anderson, Hyun Jeong, Thomas J Melia, Bryan J Bartlett, Katherine M Myers, Hanne C G Birkeland, Trond Lamark,[...]. Mol Cell 2010
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α-Synuclein impairs macroautophagy: implications for Parkinson's disease.
Ashley R Winslow, Chien-Wen Chen, Silvia Corrochano, Abraham Acevedo-Arozena, David E Gordon, Andrew A Peden, Maike Lichtenberg, Fiona M Menzies, Brinda Ravikumar, Sara Imarisio,[...]. J Cell Biol 2010
Ashley R Winslow, Chien-Wen Chen, Silvia Corrochano, Abraham Acevedo-Arozena, David E Gordon, Andrew A Peden, Maike Lichtenberg, Fiona M Menzies, Brinda Ravikumar, Sara Imarisio,[...]. J Cell Biol 2010
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Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation.
Yvette C Wong, Erika L F Holzbaur. Proc Natl Acad Sci U S A 2014
Yvette C Wong, Erika L F Holzbaur. Proc Natl Acad Sci U S A 2014
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ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase.
Ryan C Russell, Ye Tian, Haixin Yuan, Hyun Woo Park, Yu-Yun Chang, Joungmok Kim, Haerin Kim, Thomas P Neufeld, Andrew Dillin, Kun-Liang Guan. Nat Cell Biol 2013
Ryan C Russell, Ye Tian, Haixin Yuan, Hyun Woo Park, Yu-Yun Chang, Joungmok Kim, Haerin Kim, Thomas P Neufeld, Andrew Dillin, Kun-Liang Guan. Nat Cell Biol 2013
9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.