A citation-based method for searching scientific literature

Dale D O Martin, Safia Ladha, Dagmar E Ehrnhoefer, Michael R Hayden. Trends Neurosci 2015
Times Cited: 185







List of co-cited articles
1787 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease.
Marta Martinez-Vicente, Zsolt Talloczy, Esther Wong, Guomei Tang, Hiroshi Koga, Susmita Kaushik, Rosa de Vries, Esperanza Arias, Spike Harris, David Sulzer,[...]. Nat Neurosci 2010
564
35

Huntingtin functions as a scaffold for selective macroautophagy.
Yan-Ning Rui, Zhen Xu, Bindi Patel, Zhihua Chen, Dongsheng Chen, Antonio Tito, Gabriela David, Yamin Sun, Erin F Stimming, Hugo J Bellen,[...]. Nat Cell Biol 2015
259
24

Loss of autophagy in the central nervous system causes neurodegeneration in mice.
Masaaki Komatsu, Satoshi Waguri, Tomoki Chiba, Shigeo Murata, Jun-ichi Iwata, Isei Tanida, Takashi Ueno, Masato Koike, Yasuo Uchiyama, Eiki Kominami,[...]. Nature 2006
24


Potential function for the Huntingtin protein as a scaffold for selective autophagy.
Joseph Ochaba, Tamás Lukacsovich, George Csikos, Shuqiu Zheng, Julia Margulis, Lisa Salazar, Kai Mao, Alice L Lau, Sylvia Y Yeung, Sandrine Humbert,[...]. Proc Natl Acad Sci U S A 2014
174
22

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice.
Taichi Hara, Kenji Nakamura, Makoto Matsui, Akitsugu Yamamoto, Yohko Nakahara, Rika Suzuki-Migishima, Minesuke Yokoyama, Kenji Mishima, Ichiro Saito, Hideyuki Okano,[...]. Nature 2006
22

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease.
Brinda Ravikumar, Coralie Vacher, Zdenek Berger, Janet E Davies, Shouqing Luo, Lourdes G Oroz, Francesco Scaravilli, Douglas F Easton, Rainer Duden, Cahir J O'Kane,[...]. Nat Genet 2004
20


Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations.
Ju-Hyun Lee, W Haung Yu, Asok Kumar, Sooyeon Lee, Panaiyur S Mohan, Corrinne M Peterhoff, Devin M Wolfe, Marta Martinez-Vicente, Ashish C Massey, Guy Sovak,[...]. Cell 2010
783
15

Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease.
Barry Boland, Asok Kumar, Sooyeon Lee, Frances M Platt, Jerzy Wegiel, W Haung Yu, Ralph A Nixon. J Neurosci 2008
788
15

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
15

Autophagy: renovation of cells and tissues.
Noboru Mizushima, Masaaki Komatsu. Cell 2011
14

Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study.
Ralph A Nixon, Jerzy Wegiel, Asok Kumar, Wai Haung Yu, Corrinne Peterhoff, Anne Cataldo, Ana Maria Cuervo. J Neuropathol Exp Neurol 2005
14

The Biology of Huntingtin.
Frédéric Saudou, Sandrine Humbert. Neuron 2016
418
14

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.
Joungmok Kim, Mondira Kundu, Benoit Viollet, Kun-Liang Guan. Nat Cell Biol 2011
13

Trehalose alleviates polyglutamine-mediated pathology in a mouse model of Huntington disease.
Motomasa Tanaka, Yoko Machida, Sanyong Niu, Tetsurou Ikeda, Nihar R Jana, Hiroshi Doi, Masaru Kurosawa, Munenori Nekooki, Nobuyuki Nukina. Nat Med 2004
540
13

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy.
Ana Maria Cuervo, Leonidas Stefanis, Ross Fredenburg, Peter T Lansbury, David Sulzer. Science 2004
13

Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy.
Brinda Ravikumar, Rainer Duden, David C Rubinsztein. Hum Mol Genet 2002
849
13

Aβ secretion and plaque formation depend on autophagy.
Per Nilsson, Krishnapriya Loganathan, Misaki Sekiguchi, Yukio Matsuba, Kelvin Hui, Satoshi Tsubuki, Motomasa Tanaka, Nobuhisa Iwata, Takashi Saito, Takaomi C Saido. Cell Rep 2013
286
12

Huntington disease.
Gillian P Bates, Ray Dorsey, James F Gusella, Michael R Hayden, Chris Kay, Blair R Leavitt, Martha Nance, Christopher A Ross, Rachael I Scahill, Ronald Wetzel,[...]. Nat Rev Dis Primers 2015
653
12

Huntington's disease: from molecular pathogenesis to clinical treatment.
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
964
12

Polyglutamine tracts regulate beclin 1-dependent autophagy.
Avraham Ashkenazi, Carla F Bento, Thomas Ricketts, Mariella Vicinanza, Farah Siddiqi, Mariana Pavel, Ferdinando Squitieri, Maarten C Hardenberg, Sara Imarisio, Fiona M Menzies,[...]. Nature 2017
202
12


Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death.
Montserrat Arrasate, Siddhartha Mitra, Erik S Schweitzer, Mark R Segal, Steven Finkbeiner. Nature 2004
11

Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities.
Fiona M Menzies, Angeleen Fleming, Andrea Caricasole, Carla F Bento, Stephen P Andrews, Avraham Ashkenazi, Jens Füllgrabe, Anne Jackson, Maria Jimenez Sanchez, Cansu Karabiyik,[...]. Neuron 2017
595
11

Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease.
W Haung Yu, Ana Maria Cuervo, Asok Kumar, Corrinne M Peterhoff, Stephen D Schmidt, Ju-Hyun Lee, Panaiyur S Mohan, Marc Mercken, Mark R Farmery, Lars O Tjernberg,[...]. J Cell Biol 2005
731
11

Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease.
Patricia Spilman, Natalia Podlutskaya, Matthew J Hart, Jayanta Debnath, Olivia Gorostiza, Dale Bredesen, Arlan Richardson, Randy Strong, Veronica Galvan. PLoS One 2010
704
11

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy.
Michael Lazarou, Danielle A Sliter, Lesley A Kane, Shireen A Sarraf, Chunxin Wang, Jonathon L Burman, Dionisia P Sideris, Adam I Fogel, Richard J Youle. Nature 2015
10


Compromised autophagy and neurodegenerative diseases.
Fiona M Menzies, Angeleen Fleming, David C Rubinsztein. Nat Rev Neurosci 2015
500
10

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
10

Autophagy and aging.
David C Rubinsztein, Guillermo Mariño, Guido Kroemer. Cell 2011
10

Alpha-Synuclein is degraded by both autophagy and the proteasome.
Julie L Webb, Brinda Ravikumar, Jane Atkins, Jeremy N Skepper, David C Rubinsztein. J Biol Chem 2003
10

A small-molecule scaffold induces autophagy in primary neurons and protects against toxicity in a Huntington disease model.
Andrey S Tsvetkov, Jason Miller, Montserrat Arrasate, Jinny S Wong, Michael A Pleiss, Steven Finkbeiner. Proc Natl Acad Sci U S A 2010
194
9

Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.
Sovan Sarkar, Janet E Davies, Zebo Huang, Alan Tunnacliffe, David C Rubinsztein. J Biol Chem 2007
792
9

α-Synuclein impairs macroautophagy: implications for Parkinson's disease.
Ashley R Winslow, Chien-Wen Chen, Silvia Corrochano, Abraham Acevedo-Arozena, David E Gordon, Andrew A Peden, Maike Lichtenberg, Fiona M Menzies, Brinda Ravikumar, Sara Imarisio,[...]. J Cell Biol 2010
532
9

XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy.
Claudio Hetz, Peter Thielen, Soledad Matus, Melissa Nassif, Felipe Court, Roberta Kiffin, Gabriela Martinez, Ana María Cuervo, Robert H Brown, Laurie H Glimcher. Genes Dev 2009
407
9

HTT/Huntingtin in selective autophagy and Huntington disease: A foe or a friend within?
Yan-Ning Rui, Zhen Xu, Bindi Patel, Ana Maria Cuervo, Sheng Zhang. Autophagy 2015
32
28

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy.
Derek Narendra, Atsushi Tanaka, Der-Fen Suen, Richard J Youle. J Cell Biol 2008
9

A role for autophagy in Huntington's disease.
Katherine R Croce, Ai Yamamoto. Neurobiol Dis 2019
52
17

Targeting Huntingtin Expression in Patients with Huntington's Disease.
Sarah J Tabrizi, Blair R Leavitt, G Bernhard Landwehrmeyer, Edward J Wild, Carsten Saft, Roger A Barker, Nick F Blair, David Craufurd, Josef Priller, Hugh Rickards,[...]. N Engl J Med 2019
313
9

Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity.
Wenjun Song, Jin Chen, Alejandra Petrilli, Geraldine Liot, Eva Klinglmayr, Yue Zhou, Patrick Poquiz, Jonathan Tjong, Mahmoud A Pouladi, Michael R Hayden,[...]. Nat Med 2011
377
9

Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death.
Chantal Sellier, Maria-Letizia Campanari, Camille Julie Corbier, Angeline Gaucherot, Isabelle Kolb-Cheynel, Mustapha Oulad-Abdelghani, Frank Ruffenach, Adeline Page, Sorana Ciura, Edor Kabashi,[...]. EMBO J 2016
252
8

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin.
Derek P Narendra, Seok Min Jin, Atsushi Tanaka, Der-Fen Suen, Clement A Gautier, Jie Shen, Mark R Cookson, Richard J Youle. PLoS Biol 2010
8

Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons.
Karen Castillo, Melissa Nassif, Vicente Valenzuela, Fabiola Rojas, Soledad Matus, Gabriela Mercado, Felipe A Court, Brigitte van Zundert, Claudio Hetz. Autophagy 2013
237
8

The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice.
Fiona Pickford, Eliezer Masliah, Markus Britschgi, Kurt Lucin, Ramya Narasimhan, Philipp A Jaeger, Scott Small, Brian Spencer, Edward Rockenstein, Beth Levine,[...]. J Clin Invest 2008
811
8

Hereditary early-onset Parkinson's disease caused by mutations in PINK1.
Enza Maria Valente, Patrick M Abou-Sleiman, Viviana Caputo, Miratul M K Muqit, Kirsten Harvey, Suzana Gispert, Zeeshan Ali, Domenico Del Turco, Anna Rita Bentivoglio, Daniel G Healy,[...]. Science 2004
8

Novel synthetic small-molecule activators of AMPK as enhancers of autophagy and amyloid-β peptide degradation.
Valérie Vingtdeux, Pallavi Chandakkar, Haitian Zhao, Cristina d'Abramo, Peter Davies, Philippe Marambaud. FASEB J 2011
167
8

Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases.
Brian Spencer, Rewati Potkar, Margarita Trejo, Edward Rockenstein, Christina Patrick, Ryan Gindi, Anthony Adame, Tony Wyss-Coray, Eliezer Masliah. J Neurosci 2009
444
8

Rapamycin treatment augments motor neuron degeneration in SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
Xiaojie Zhang, Liang Li, Sheng Chen, Dehua Yang, Yi Wang, Xin Zhang, Zheng Wang, Weidong Le. Autophagy 2011
270
8


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.