A citation-based method for searching scientific literature

Ryan J Davis, Markus Welcker, Bruce E Clurman. Cancer Cell 2014
Times Cited: 235







List of co-cited articles
835 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity



FBXW7: a critical tumor suppressor of human cancers.
Chien-Hung Yeh, Marcia Bellon, Christophe Nicot. Mol Cancer 2018
199
21

SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
Hiroyuki Inuzuka, Shavali Shaik, Ichiro Onoyama, Daming Gao, Alan Tseng, Richard S Maser, Bo Zhai, Lixin Wan, Alejandro Gutierrez, Alan W Lau,[...]. Nature 2011
474
20

The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation.
Markus Welcker, Amir Orian, Jianping Jin, Jonathan E Grim, J Wade Harper, Robert N Eisenman, Bruce E Clurman. Proc Natl Acad Sci U S A 2004
651
19

Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases.
Bing Hao, Stephanie Oehlmann, Mathew E Sowa, J Wade Harper, Nikola P Pavletich. Mol Cell 2007
331
18

Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7.
Masayoshi Yada, Shigetsugu Hatakeyama, Takumi Kamura, Masaaki Nishiyama, Ryosuke Tsunematsu, Hiroyuki Imaki, Noriko Ishida, Fumihiko Okumura, Keiko Nakayama, Keiichi I Nakayama. EMBO J 2004
575
17

Fbw7 dimerization determines the specificity and robustness of substrate degradation.
Markus Welcker, Elizabeth A Larimore, Jherek Swanger, Maria T Bengoechea-Alonso, Jonathan E Grim, Johan Ericsson, Ning Zheng, Bruce E Clurman. Genes Dev 2013
66
24

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors.
Jennifer O'Neil, Jonathan Grim, Peter Strack, Sudhir Rao, Deanne Tibbitts, Christopher Winter, James Hardwick, Markus Welcker, Jules P Meijerink, Rob Pieters,[...]. J Exp Med 2007
499
15

A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size.
Markus Welcker, Amir Orian, Jonathan E Grim, Robert N Eisenman, Bruce E Clurman. Curr Biol 2004
235
15

FBXW7/hCDC4 is a general tumor suppressor in human cancer.
Shahab Akhoondi, Dahui Sun, Natalie von der Lehr, Sophia Apostolidou, Kathleen Klotz, Alena Maljukova, Diana Cepeda, Heidi Fiegl, Dimitra Dafou, Christian Marth,[...]. Cancer Res 2007
369
14

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase.
D M Koepp, L K Schaefer, X Ye, K Keyomarsi, C Chu, J W Harper, S J Elledge. Science 2001
628
13

Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomerase.
Sang-Hyun Min, Alan W Lau, Tae Ho Lee, Hiroyuki Inuzuka, Shuo Wei, Pengyu Huang, Shavali Shaik, Daniel Yenhong Lee, Greg Finn, Martin Balastik,[...]. Mol Cell 2012
119
13

FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression.
Jian-Hua Mao, Il-Jin Kim, Di Wu, Joan Climent, Hio Chung Kang, Reyno DelRosario, Allan Balmain. Science 2008
311
12

The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability.
Bryan King, Thomas Trimarchi, Linsey Reavie, Luyao Xu, Jasper Mullenders, Panagiotis Ntziachristos, Beatriz Aranda-Orgilles, Arianne Perez-Garcia, Junwei Shi, Christopher Vakoc,[...]. Cell 2013
222
12

Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7.
Ingrid E Wertz, Saritha Kusam, Cynthia Lam, Toru Okamoto, Wendy Sandoval, Daniel J Anderson, Elizabeth Helgason, James A Ernst, Mike Eby, Jinfeng Liu,[...]. Nature 2011
575
12

Aberrant regulation of FBW7 in cancer.
Lixia Wang, Xiantao Ye, Yueyong Liu, Wenyi Wei, Zhiwei Wang. Oncotarget 2014
69
15

Isoform- and cell cycle-dependent substrate degradation by the Fbw7 ubiquitin ligase.
Jonathan E Grim, Michael P Gustafson, Roli K Hirata, Amanda C Hagar, Jherek Swanger, Markus Welcker, Harry C Hwang, Johan Ericsson, David W Russell, Bruce E Clurman. J Cell Biol 2008
84
13

Inactivation of hCDC4 can cause chromosomal instability.
Harith Rajagopalan, Prasad V Jallepalli, Carlo Rago, Victor E Velculescu, Kenneth W Kinzler, Bert Vogelstein, Christoph Lengauer. Nature 2004
439
11

Inactivation of FBXW7/hCDC4-β expression by promoter hypermethylation is associated with favorable prognosis in primary breast cancer.
Shahab Akhoondi, Linda Lindström, Martin Widschwendter, Martin Corcoran, Jonas Bergh, Charles Spruck, Dan Grandér, Olle Sangfelt. Breast Cancer Res 2010
60
18

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line.
H Strohmaier, C H Spruck, P Kaiser, K A Won, O Sangfelt, S I Reed. Nature 2001
489
11

Physiological functions of FBW7 in cancer and metabolism.
Kouhei Shimizu, Naoe Taira Nihira, Hiroyuki Inuzuka, Wenyi Wei. Cell Signal 2018
31
35

The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia.
Benjamin J Thompson, Silvia Buonamici, Maria Luisa Sulis, Teresa Palomero, Tomas Vilimas, Giuseppe Basso, Adolfo Ferrando, Iannis Aifantis. J Exp Med 2007
351
10

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
10

FBXW7 in Cancer: What Has Been Unraveled Thus Far?
Bethsebie Lalduhsaki Sailo, Kishore Banik, Sosmitha Girisa, Devivasha Bordoloi, Lu Fan, Clarissa Esmeralda Halim, Hong Wang, Alan Prem Kumar, Dali Zheng, Xinliang Mao,[...]. Cancers (Basel) 2019
81
12

Fbxw7α- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma.
Luca Busino, Scott E Millman, Luigi Scotto, Christos A Kyratsous, Venkatesha Basrur, Owen O'Connor, Alexander Hoffmann, Kojo S Elenitoba-Johnson, Michele Pagano. Nat Cell Biol 2012
133
9

The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data.
Ethan Cerami, Jianjiong Gao, Ugur Dogrusoz, Benjamin E Gross, Selcuk Onur Sumer, Bülent Arman Aksoy, Anders Jacobsen, Caitlin J Byrne, Michael L Heuer, Erik Larsson,[...]. Cancer Discov 2012
9

Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation.
Markus Welcker, Jeffrey Singer, Keith R Loeb, Jonathan Grim, Andrew Bloecher, Mark Gurien-West, Bruce E Clurman, James M Roberts. Mol Cell 2003
291
9

Ubiquitin ligases: cell-cycle control and cancer.
Keiichi I Nakayama, Keiko Nakayama. Nat Rev Cancer 2006
9

Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene.
Jian-Hua Mao, Jesus Perez-Losada, Di Wu, Reyno Delrosario, Ryosuke Tsunematsu, Keiichi I Nakayama, Ken Brown, Sheila Bryson, Allan Balmain. Nature 2004
306
9

The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase.
Wenyi Wei, Jianping Jin, Susanne Schlisio, J Wade Harper, William G Kaelin. Cancer Cell 2005
321
9

FBXW7α attenuates inflammatory signalling by downregulating C/EBPδ and its target gene Tlr4.
Kuppusamy Balamurugan, Shikha Sharan, Kimberly D Klarmann, Youhong Zhang, Vincenzo Coppola, Glenn H Summers, Thierry Roger, Deborah K Morrison, Jonathan R Keller, Esta Sterneck. Nat Commun 2013
62
12

hCDC4b, a regulator of cyclin E, as a direct transcriptional target of p53.
Takashi Kimura, Mitsukazu Gotoh, Yusuke Nakamura, Hirofumi Arakawa. Cancer Sci 2003
93
8

Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway.
Azadeh Arabi, Karim Ullah, Rui M M Branca, Johan Johansson, Daniel Bandarra, Moritz Haneklaus, Jing Fu, Ingrid Ariës, Peter Nilsson, Monique L Den Boer,[...]. Nat Commun 2012
66
12

Tumor suppressor functions of FBW7 in cancer development and progression.
Zhiwei Wang, Hiroyuki Inuzuka, Jiateng Zhong, Lixin Wan, Hidefumi Fukushima, Fazlul H Sarkar, Wenyi Wei. FEBS Lett 2012
126
8

Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL.
Sahoko Matsuoka, Yuichi Oike, Ichiro Onoyama, Atsushi Iwama, Fumio Arai, Keiyo Takubo, Yoichi Mashimo, Hideyuki Oguro, Eriko Nitta, Keisuke Ito,[...]. Genes Dev 2008
143
8

hCDC4 gene mutations in endometrial cancer.
Charles H Spruck, Heimo Strohmaier, Olle Sangfelt, Hannes M Müller, Michael Hubalek, Elisabeth Müller-Holzner, Christian Marth, Martin Widschwendter, Steven I Reed. Cancer Res 2002
228
8

Loss of FBXW7, a cell cycle regulating gene, in colorectal cancer: clinical significance.
Masaaki Iwatsuki, Koshi Mimori, Hideshi Ishii, Takehiko Yokobori, Yasushi Takatsuno, Tetsuya Sato, Hiroyuki Toh, Ichiro Onoyama, Keiichi I Nakayama, Hideo Baba,[...]. Int J Cancer 2010
111
8

ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer.
Shunrong Ji, Yi Qin, Si Shi, Xiangyuan Liu, Hongli Hu, Hu Zhou, Jing Gao, Bo Zhang, Wenyan Xu, Jiang Liu,[...]. Cell Res 2015
89
8

RING domain E3 ubiquitin ligases.
Raymond J Deshaies, Claudio A P Joazeiro. Annu Rev Biochem 2009
8

The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling.
Abdolrahman S Nateri, Lluís Riera-Sans, Clive Da Costa, Axel Behrens. Science 2004
300
8

Recent insight into the role of FBXW7 as a tumor suppressor.
Kanae Yumimoto, Keiichi I Nakayama. Semin Cancer Biol 2020
41
19

Function and regulation of cullin-RING ubiquitin ligases.
Matthew D Petroski, Raymond J Deshaies. Nat Rev Mol Cell Biol 2005
7

Fbxw7 Tumor Suppressor: A Vital Regulator Contributes to Human Tumorigenesis.
Jun Cao, Ming-Hua Ge, Zhi-Qiang Ling. Medicine (Baltimore) 2016
56
12

FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation.
Roya Babaei-Jadidi, Ningning Li, Anas Saadeddin, Bradley Spencer-Dene, Anett Jandke, Belal Muhammad, ElSayed E Ibrahim, Ranjithmenon Muraleedharan, Mohammed Abuzinadah, Hayley Davis,[...]. J Exp Med 2011
132
7

Fbw7/hCDC4 dimerization regulates its substrate interactions.
Markus Welcker, Bruce E Clurman. Cell Div 2007
102
7

Mechanisms and function of substrate recruitment by F-box proteins.
Jeffrey R Skaar, Julia K Pagan, Michele Pagano. Nat Rev Mol Cell Biol 2013
413
7

The ubiquitin system.
A Hershko, A Ciechanover. Annu Rev Biochem 1998
7

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer.
Teresa A Soucy, Peter G Smith, Michael A Milhollen, Allison J Berger, James M Gavin, Sharmila Adhikari, James E Brownell, Kristine E Burke, David P Cardin, Stephen Critchley,[...]. Nature 2009
7

F-box protein FBXW7 inhibits cancer metastasis in a non-cell-autonomous manner.
Kanae Yumimoto, Sayuri Akiyoshi, Hiroki Ueo, Yasuaki Sagara, Ichiro Onoyama, Hiroaki Ueo, Shinji Ohno, Masaki Mori, Koshi Mimori, Keiichi I Nakayama. J Clin Invest 2015
77
9

FBXW7 modulates cellular stress response and metastatic potential through ​HSF1 post-translational modification.
Nikos Kourtis, Rana S Moubarak, Beatriz Aranda-Orgilles, Kevin Lui, Iraz T Aydin, Thomas Trimarchi, Farbod Darvishian, Christine Salvaggio, Judy Zhong, Kamala Bhatt,[...]. Nat Cell Biol 2015
74
9


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.