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Times Cited: 1261
Times Cited: 1261
Times Cited
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A Unifying Mechanism for Mitochondrial Superoxide Production during Ischemia-Reperfusion Injury.
Edward T Chouchani, Victoria R Pell, Andrew M James, Lorraine M Work, Kourosh Saeb-Parsy, Christian Frezza, Thomas Krieg, Michael P Murphy. Cell Metab 2016
Edward T Chouchani, Victoria R Pell, Andrew M James, Lorraine M Work, Kourosh Saeb-Parsy, Christian Frezza, Thomas Krieg, Michael P Murphy. Cell Metab 2016
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Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages.
Evanna L Mills, Beth Kelly, Angela Logan, Ana S H Costa, Mukund Varma, Clare E Bryant, Panagiotis Tourlomousis, J Henry M Däbritz, Eyal Gottlieb, Isabel Latorre,[...]. Cell 2016
Evanna L Mills, Beth Kelly, Angela Logan, Ana S H Costa, Mukund Varma, Clare E Bryant, Panagiotis Tourlomousis, J Henry M Däbritz, Eyal Gottlieb, Isabel Latorre,[...]. Cell 2016
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Mitochondrial ROS Produced via Reverse Electron Transport Extend Animal Lifespan.
Filippo Scialò, Ashwin Sriram, Daniel Fernández-Ayala, Nina Gubina, Madis Lõhmus, Glyn Nelson, Angela Logan, Helen M Cooper, Plácido Navas, Jose Antonio Enríquez,[...]. Cell Metab 2016
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Control of mitochondrial superoxide production by reverse electron transport at complex I.
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Ellen L Robb, Andrew R Hall, Tracy A Prime, Simon Eaton, Marten Szibor, Carlo Viscomi, Andrew M James, Michael P Murphy. J Biol Chem 2018
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Superoxide is produced by the reduced flavin in mitochondrial complex I: a single, unified mechanism that applies during both forward and reverse electron transfer.
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Role of Mitochondrial Reverse Electron Transport in ROS Signaling: Potential Roles in Health and Disease.
Filippo Scialò, Daniel J Fernández-Ayala, Alberto Sanz. Front Physiol 2017
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Succinate is an inflammatory signal that induces IL-1β through HIF-1α.
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Accumulation of Succinate in Cardiac Ischemia Primarily Occurs via Canonical Krebs Cycle Activity.
Jimmy Zhang, Yves T Wang, James H Miller, Mary M Day, Joshua C Munger, Paul S Brookes. Cell Rep 2018
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The CoQH2/CoQ Ratio Serves as a Sensor of Respiratory Chain Efficiency.
Adela Guarás, Ester Perales-Clemente, Enrique Calvo, Rebeca Acín-Pérez, Marta Loureiro-Lopez, Claire Pujol, Isabel Martínez-Carrascoso, Estefanía Nuñez, Fernando García-Marqués, María Angeles Rodríguez-Hernández,[...]. Cell Rep 2016
Adela Guarás, Ester Perales-Clemente, Enrique Calvo, Rebeca Acín-Pérez, Marta Loureiro-Lopez, Claire Pujol, Isabel Martínez-Carrascoso, Estefanía Nuñez, Fernando García-Marqués, María Angeles Rodríguez-Hernández,[...]. Cell Rep 2016
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Oxygen Sensing by Arterial Chemoreceptors Depends on Mitochondrial Complex I Signaling.
M Carmen Fernández-Agüera, Lin Gao, Patricia González-Rodríguez, C Oscar Pintado, Ignacio Arias-Mayenco, Paula García-Flores, Antonio García-Pergañeda, Alberto Pascual, Patricia Ortega-Sáenz, José López-Barneo. Cell Metab 2015
M Carmen Fernández-Agüera, Lin Gao, Patricia González-Rodríguez, C Oscar Pintado, Ignacio Arias-Mayenco, Paula García-Flores, Antonio García-Pergañeda, Alberto Pascual, Patricia Ortega-Sáenz, José López-Barneo. Cell Metab 2015
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Structural basis for a complex I mutation that blocks pathological ROS production.
Zhan Yin, Nils Burger, Duvaraka Kula-Alwar, Dunja Aksentijević, Hannah R Bridges, Hiran A Prag, Daniel N Grba, Carlo Viscomi, Andrew M James, Amin Mottahedin,[...]. Nat Commun 2021
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Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation.
Vicky Lampropoulou, Alexey Sergushichev, Monika Bambouskova, Sharmila Nair, Emma E Vincent, Ekaterina Loginicheva, Luisa Cervantes-Barragan, Xiucui Ma, Stanley Ching-Cheng Huang, Takla Griss,[...]. Cell Metab 2016
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Acute O2 Sensing: Role of Coenzyme QH2/Q Ratio and Mitochondrial ROS Compartmentalization.
Ignacio Arias-Mayenco, Patricia González-Rodríguez, Hortensia Torres-Torrelo, Lin Gao, M Carmen Fernández-Agüera, Victoria Bonilla-Henao, Patricia Ortega-Sáenz, José López-Barneo. Cell Metab 2018
Ignacio Arias-Mayenco, Patricia González-Rodríguez, Hortensia Torres-Torrelo, Lin Gao, M Carmen Fernández-Agüera, Victoria Bonilla-Henao, Patricia Ortega-Sáenz, José López-Barneo. Cell Metab 2018
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Novel Real-time Prediction of Liver Graft Function During Hypothermic Oxygenated Machine Perfusion Before Liver Transplantation.
Xavier Muller, Andrea Schlegel, Philipp Kron, Dilmurodjon Eshmuminov, Michael Würdinger, David Meierhofer, Pierre-Alain Clavien, Philipp Dutkowski. Ann Surg 2019
Xavier Muller, Andrea Schlegel, Philipp Kron, Dilmurodjon Eshmuminov, Michael Würdinger, David Meierhofer, Pierre-Alain Clavien, Philipp Dutkowski. Ann Surg 2019
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Succinate, an intermediate in metabolism, signal transduction, ROS, hypoxia, and tumorigenesis.
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Mitochondrial generation of superoxide and hydrogen peroxide as the source of mitochondrial redox signaling.
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Hoi-Shan Wong, Pratiksha A Dighe, Vojtech Mezera, Pierre-Axel Monternier, Martin D Brand. J Biol Chem 2017
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ROS function in redox signaling and oxidative stress.
Michael Schieber, Navdeep S Chandel. Curr Biol 2014
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Ischemia and reperfusion--from mechanism to translation.
Holger K Eltzschig, Tobias Eckle. Nat Med 2011
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Circulating mitochondrial DAMPs cause inflammatory responses to injury.
Qin Zhang, Mustafa Raoof, Yu Chen, Yuka Sumi, Tolga Sursal, Wolfgang Junger, Karim Brohi, Kiyoshi Itagaki, Carl J Hauser. Nature 2010
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Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation.
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Elizabeth Murphy, Charles Steenbergen. Physiol Rev 2008
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Mitochondrial Dysfunction and Myocardial Ischemia-Reperfusion: Implications for Novel Therapies.
Edward J Lesnefsky, Qun Chen, Bernard Tandler, Charles L Hoppel. Annu Rev Pharmacol Toxicol 2017
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Heart Disease and Stroke Statistics-2020 Update: A Report From the American Heart Association.
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Salim S Virani, Alvaro Alonso, Emelia J Benjamin, Marcio S Bittencourt, Clifton W Callaway, April P Carson, Alanna M Chamberlain, Alexander R Chang, Susan Cheng, Francesca N Delling,[...]. Circulation 2020
4
Reverse electron flow-mediated ROS generation in ischemia-damaged mitochondria: role of complex I inhibition vs. depolarization of inner mitochondrial membrane.
Thomas Ross, Karol Szczepanek, Elizabeth Bowler, Ying Hu, Andrew Larner, Edward J Lesnefsky, Qun Chen. Biochim Biophys Acta 2013
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Hypothermic Machine Perfusion in Liver Transplantation - A Randomized Trial.
Rianne van Rijn, Ivo J Schurink, Yvonne de Vries, Aad P van den Berg, Miriam Cortes Cerisuelo, Sarwa Darwish Murad, Joris I Erdmann, Nicholas Gilbo, Robbert J de Haas, Nigel Heaton,[...]. N Engl J Med 2021
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Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Evanna L Mills, Dylan G Ryan, Hiran A Prag, Dina Dikovskaya, Deepthi Menon, Zbigniew Zaslona, Mark P Jedrychowski, Ana S H Costa, Maureen Higgins, Emily Hams,[...]. Nature 2018
Evanna L Mills, Dylan G Ryan, Hiran A Prag, Dina Dikovskaya, Deepthi Menon, Zbigniew Zaslona, Mark P Jedrychowski, Ana S H Costa, Maureen Higgins, Emily Hams,[...]. Nature 2018
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A role for mitochondria in NLRP3 inflammasome activation.
Rongbin Zhou, Amir S Yazdi, Philippe Menu, Jürg Tschopp. Nature 2011
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Topology of superoxide production from different sites in the mitochondrial electron transport chain.
Julie St-Pierre, Julie A Buckingham, Stephen J Roebuck, Martin D Brand. J Biol Chem 2002
Julie St-Pierre, Julie A Buckingham, Stephen J Roebuck, Martin D Brand. J Biol Chem 2002
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Suppressors of Superoxide-H2O2 Production at Site IQ of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury.
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Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program.
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Mireille Khacho, Alysen Clark, Devon S Svoboda, Joelle Azzi, Jason G MacLaurin, Cynthia Meghaizel, Hiromi Sesaki, Diane C Lagace, Marc Germain, Mary-Ellen Harper,[...]. Cell Stem Cell 2016
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Fundamental Mechanisms of Regulated Cell Death and Implications for Heart Disease.
Dominic P Del Re, Dulguun Amgalan, Andreas Linkermann, Qinghang Liu, Richard N Kitsis. Physiol Rev 2019
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Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction.
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Heart Disease and Stroke Statistics-2021 Update: A Report From the American Heart Association.
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Karol Fiedorczuk, James A Letts, Gianluca Degliesposti, Karol Kaszuba, Mark Skehel, Leonid A Sazanov. Nature 2016
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.