Edward T Chouchani, Victoria R Pell, Edoardo Gaude, Dunja Aksentijević, Stephanie Y Sundier, Ellen L Robb, Angela Logan, Sergiy M Nadtochiy, Emily N J Ord, Anthony C Smith, Filmon Eyassu, Rachel Shirley, Chou-Hui Hu, Anna J Dare, Andrew M James, Sebastian Rogatti, Richard C Hartley, Simon Eaton, Ana S H Costa, Paul S Brookes, Sean M Davidson, Michael R Duchen, Kourosh Saeb-Parsy, Michael J Shattock, Alan J Robinson, Lorraine M Work, Christian Frezza, Thomas Krieg, Michael P Murphy. Nature 2014
Times Cited: 1261
Times Cited: 1261
Times Cited
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A Unifying Mechanism for Mitochondrial Superoxide Production during Ischemia-Reperfusion Injury.
Edward T Chouchani, Victoria R Pell, Andrew M James, Lorraine M Work, Kourosh Saeb-Parsy, Christian Frezza, Thomas Krieg, Michael P Murphy. Cell Metab 2016
Edward T Chouchani, Victoria R Pell, Andrew M James, Lorraine M Work, Kourosh Saeb-Parsy, Christian Frezza, Thomas Krieg, Michael P Murphy. Cell Metab 2016
15
Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages.
Evanna L Mills, Beth Kelly, Angela Logan, Ana S H Costa, Mukund Varma, Clare E Bryant, Panagiotis Tourlomousis, J Henry M Däbritz, Eyal Gottlieb, Isabel Latorre,[...]. Cell 2016
Evanna L Mills, Beth Kelly, Angela Logan, Ana S H Costa, Mukund Varma, Clare E Bryant, Panagiotis Tourlomousis, J Henry M Däbritz, Eyal Gottlieb, Isabel Latorre,[...]. Cell 2016
12
Mitochondrial ROS Produced via Reverse Electron Transport Extend Animal Lifespan.
Filippo Scialò, Ashwin Sriram, Daniel Fernández-Ayala, Nina Gubina, Madis Lõhmus, Glyn Nelson, Angela Logan, Helen M Cooper, Plácido Navas, Jose Antonio Enríquez,[...]. Cell Metab 2016
Filippo Scialò, Ashwin Sriram, Daniel Fernández-Ayala, Nina Gubina, Madis Lõhmus, Glyn Nelson, Angela Logan, Helen M Cooper, Plácido Navas, Jose Antonio Enríquez,[...]. Cell Metab 2016
8
Control of mitochondrial superoxide production by reverse electron transport at complex I.
Ellen L Robb, Andrew R Hall, Tracy A Prime, Simon Eaton, Marten Szibor, Carlo Viscomi, Andrew M James, Michael P Murphy. J Biol Chem 2018
Ellen L Robb, Andrew R Hall, Tracy A Prime, Simon Eaton, Marten Szibor, Carlo Viscomi, Andrew M James, Michael P Murphy. J Biol Chem 2018
8
Superoxide is produced by the reduced flavin in mitochondrial complex I: a single, unified mechanism that applies during both forward and reverse electron transfer.
Kenneth R Pryde, Judy Hirst. J Biol Chem 2011
Kenneth R Pryde, Judy Hirst. J Biol Chem 2011
8
Role of Mitochondrial Reverse Electron Transport in ROS Signaling: Potential Roles in Health and Disease.
Filippo Scialò, Daniel J Fernández-Ayala, Alberto Sanz. Front Physiol 2017
Filippo Scialò, Daniel J Fernández-Ayala, Alberto Sanz. Front Physiol 2017
8
Succinate is an inflammatory signal that induces IL-1β through HIF-1α.
G M Tannahill, A M Curtis, J Adamik, E M Palsson-McDermott, A F McGettrick, G Goel, C Frezza, N J Bernard, B Kelly, N H Foley,[...]. Nature 2013
G M Tannahill, A M Curtis, J Adamik, E M Palsson-McDermott, A F McGettrick, G Goel, C Frezza, N J Bernard, B Kelly, N H Foley,[...]. Nature 2013
8
Accumulation of Succinate in Cardiac Ischemia Primarily Occurs via Canonical Krebs Cycle Activity.
Jimmy Zhang, Yves T Wang, James H Miller, Mary M Day, Joshua C Munger, Paul S Brookes. Cell Rep 2018
Jimmy Zhang, Yves T Wang, James H Miller, Mary M Day, Joshua C Munger, Paul S Brookes. Cell Rep 2018
10
The CoQH2/CoQ Ratio Serves as a Sensor of Respiratory Chain Efficiency.
Adela Guarás, Ester Perales-Clemente, Enrique Calvo, Rebeca Acín-Pérez, Marta Loureiro-Lopez, Claire Pujol, Isabel Martínez-Carrascoso, Estefanía Nuñez, Fernando García-Marqués, María Angeles Rodríguez-Hernández,[...]. Cell Rep 2016
Adela Guarás, Ester Perales-Clemente, Enrique Calvo, Rebeca Acín-Pérez, Marta Loureiro-Lopez, Claire Pujol, Isabel Martínez-Carrascoso, Estefanía Nuñez, Fernando García-Marqués, María Angeles Rodríguez-Hernández,[...]. Cell Rep 2016
7
Oxygen Sensing by Arterial Chemoreceptors Depends on Mitochondrial Complex I Signaling.
M Carmen Fernández-Agüera, Lin Gao, Patricia González-Rodríguez, C Oscar Pintado, Ignacio Arias-Mayenco, Paula García-Flores, Antonio García-Pergañeda, Alberto Pascual, Patricia Ortega-Sáenz, José López-Barneo. Cell Metab 2015
M Carmen Fernández-Agüera, Lin Gao, Patricia González-Rodríguez, C Oscar Pintado, Ignacio Arias-Mayenco, Paula García-Flores, Antonio García-Pergañeda, Alberto Pascual, Patricia Ortega-Sáenz, José López-Barneo. Cell Metab 2015
7
Structural basis for a complex I mutation that blocks pathological ROS production.
Zhan Yin, Nils Burger, Duvaraka Kula-Alwar, Dunja Aksentijević, Hannah R Bridges, Hiran A Prag, Daniel N Grba, Carlo Viscomi, Andrew M James, Amin Mottahedin,[...]. Nat Commun 2021
Zhan Yin, Nils Burger, Duvaraka Kula-Alwar, Dunja Aksentijević, Hannah R Bridges, Hiran A Prag, Daniel N Grba, Carlo Viscomi, Andrew M James, Amin Mottahedin,[...]. Nat Commun 2021
31
Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation.
Vicky Lampropoulou, Alexey Sergushichev, Monika Bambouskova, Sharmila Nair, Emma E Vincent, Ekaterina Loginicheva, Luisa Cervantes-Barragan, Xiucui Ma, Stanley Ching-Cheng Huang, Takla Griss,[...]. Cell Metab 2016
Vicky Lampropoulou, Alexey Sergushichev, Monika Bambouskova, Sharmila Nair, Emma E Vincent, Ekaterina Loginicheva, Luisa Cervantes-Barragan, Xiucui Ma, Stanley Ching-Cheng Huang, Takla Griss,[...]. Cell Metab 2016
6
Acute O2 Sensing: Role of Coenzyme QH2/Q Ratio and Mitochondrial ROS Compartmentalization.
Ignacio Arias-Mayenco, Patricia González-Rodríguez, Hortensia Torres-Torrelo, Lin Gao, M Carmen Fernández-Agüera, Victoria Bonilla-Henao, Patricia Ortega-Sáenz, José López-Barneo. Cell Metab 2018
Ignacio Arias-Mayenco, Patricia González-Rodríguez, Hortensia Torres-Torrelo, Lin Gao, M Carmen Fernández-Agüera, Victoria Bonilla-Henao, Patricia Ortega-Sáenz, José López-Barneo. Cell Metab 2018
14
Novel Real-time Prediction of Liver Graft Function During Hypothermic Oxygenated Machine Perfusion Before Liver Transplantation.
Xavier Muller, Andrea Schlegel, Philipp Kron, Dilmurodjon Eshmuminov, Michael Würdinger, David Meierhofer, Pierre-Alain Clavien, Philipp Dutkowski. Ann Surg 2019
Xavier Muller, Andrea Schlegel, Philipp Kron, Dilmurodjon Eshmuminov, Michael Würdinger, David Meierhofer, Pierre-Alain Clavien, Philipp Dutkowski. Ann Surg 2019
7
Transplantation of discarded livers following viability testing with normothermic machine perfusion.
Hynek Mergental, Richard W Laing, Amanda J Kirkham, M Thamara P R Perera, Yuri L Boteon, Joseph Attard, Darren Barton, Stuart Curbishley, Manpreet Wilkhu, Desley A H Neil,[...]. Nat Commun 2020
Hynek Mergental, Richard W Laing, Amanda J Kirkham, M Thamara P R Perera, Yuri L Boteon, Joseph Attard, Darren Barton, Stuart Curbishley, Manpreet Wilkhu, Desley A H Neil,[...]. Nat Commun 2020
5
Succinate, an intermediate in metabolism, signal transduction, ROS, hypoxia, and tumorigenesis.
Laszlo Tretter, Attila Patocs, Christos Chinopoulos. Biochim Biophys Acta 2016
Laszlo Tretter, Attila Patocs, Christos Chinopoulos. Biochim Biophys Acta 2016
5
Mitochondrial generation of superoxide and hydrogen peroxide as the source of mitochondrial redox signaling.
Martin D Brand. Free Radic Biol Med 2016
Martin D Brand. Free Radic Biol Med 2016
5
Model for hypoxic pulmonary vasoconstriction involving mitochondrial oxygen sensing.
G B Waypa, N S Chandel, P T Schumacker. Circ Res 2001
G B Waypa, N S Chandel, P T Schumacker. Circ Res 2001
5
Production of superoxide and hydrogen peroxide from specific mitochondrial sites under different bioenergetic conditions.
Hoi-Shan Wong, Pratiksha A Dighe, Vojtech Mezera, Pierre-Axel Monternier, Martin D Brand. J Biol Chem 2017
Hoi-Shan Wong, Pratiksha A Dighe, Vojtech Mezera, Pierre-Axel Monternier, Martin D Brand. J Biol Chem 2017
5
ROS function in redox signaling and oxidative stress.
Michael Schieber, Navdeep S Chandel. Curr Biol 2014
Michael Schieber, Navdeep S Chandel. Curr Biol 2014
5
Ischemia and reperfusion--from mechanism to translation.
Holger K Eltzschig, Tobias Eckle. Nat Med 2011
Holger K Eltzschig, Tobias Eckle. Nat Med 2011
5
Circulating mitochondrial DAMPs cause inflammatory responses to injury.
Qin Zhang, Mustafa Raoof, Yu Chen, Yuka Sumi, Tolga Sursal, Wolfgang Junger, Karim Brohi, Kiyoshi Itagaki, Carl J Hauser. Nature 2010
Qin Zhang, Mustafa Raoof, Yu Chen, Yuka Sumi, Tolga Sursal, Wolfgang Junger, Karim Brohi, Kiyoshi Itagaki, Carl J Hauser. Nature 2010
5
Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation.
Jack L Martin, Ana S H Costa, Anja V Gruszczyk, Timothy E Beach, Fay M Allen, Hiran A Prag, Elizabeth C Hinchy, Krishnaa Mahbubani, Mazin Hamed, Laura Tronci,[...]. Nat Metab 2019
Jack L Martin, Ana S H Costa, Anja V Gruszczyk, Timothy E Beach, Fay M Allen, Hiran A Prag, Elizabeth C Hinchy, Krishnaa Mahbubani, Mazin Hamed, Laura Tronci,[...]. Nat Metab 2019
8
Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury.
Elizabeth Murphy, Charles Steenbergen. Physiol Rev 2008
Elizabeth Murphy, Charles Steenbergen. Physiol Rev 2008
4
Cell biology of ischemia/reperfusion injury.
Theodore Kalogeris, Christopher P Baines, Maike Krenz, Ronald J Korthuis. Int Rev Cell Mol Biol 2012
Theodore Kalogeris, Christopher P Baines, Maike Krenz, Ronald J Korthuis. Int Rev Cell Mol Biol 2012
4
Mitochondrial Dysfunction and Myocardial Ischemia-Reperfusion: Implications for Novel Therapies.
Edward J Lesnefsky, Qun Chen, Bernard Tandler, Charles L Hoppel. Annu Rev Pharmacol Toxicol 2017
Edward J Lesnefsky, Qun Chen, Bernard Tandler, Charles L Hoppel. Annu Rev Pharmacol Toxicol 2017
4
Heart Disease and Stroke Statistics-2020 Update: A Report From the American Heart Association.
Salim S Virani, Alvaro Alonso, Emelia J Benjamin, Marcio S Bittencourt, Clifton W Callaway, April P Carson, Alanna M Chamberlain, Alexander R Chang, Susan Cheng, Francesca N Delling,[...]. Circulation 2020
Salim S Virani, Alvaro Alonso, Emelia J Benjamin, Marcio S Bittencourt, Clifton W Callaway, April P Carson, Alanna M Chamberlain, Alexander R Chang, Susan Cheng, Francesca N Delling,[...]. Circulation 2020
4
Reverse electron flow-mediated ROS generation in ischemia-damaged mitochondria: role of complex I inhibition vs. depolarization of inner mitochondrial membrane.
Thomas Ross, Karol Szczepanek, Elizabeth Bowler, Ying Hu, Andrew Larner, Edward J Lesnefsky, Qun Chen. Biochim Biophys Acta 2013
Thomas Ross, Karol Szczepanek, Elizabeth Bowler, Ying Hu, Andrew Larner, Edward J Lesnefsky, Qun Chen. Biochim Biophys Acta 2013
17
Hypothermic Machine Perfusion in Liver Transplantation - A Randomized Trial.
Rianne van Rijn, Ivo J Schurink, Yvonne de Vries, Aad P van den Berg, Miriam Cortes Cerisuelo, Sarwa Darwish Murad, Joris I Erdmann, Nicholas Gilbo, Robbert J de Haas, Nigel Heaton,[...]. N Engl J Med 2021
Rianne van Rijn, Ivo J Schurink, Yvonne de Vries, Aad P van den Berg, Miriam Cortes Cerisuelo, Sarwa Darwish Murad, Joris I Erdmann, Nicholas Gilbo, Robbert J de Haas, Nigel Heaton,[...]. N Engl J Med 2021
6
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Evanna L Mills, Dylan G Ryan, Hiran A Prag, Dina Dikovskaya, Deepthi Menon, Zbigniew Zaslona, Mark P Jedrychowski, Ana S H Costa, Maureen Higgins, Emily Hams,[...]. Nature 2018
Evanna L Mills, Dylan G Ryan, Hiran A Prag, Dina Dikovskaya, Deepthi Menon, Zbigniew Zaslona, Mark P Jedrychowski, Ana S H Costa, Maureen Higgins, Emily Hams,[...]. Nature 2018
4
A role for mitochondria in NLRP3 inflammasome activation.
Rongbin Zhou, Amir S Yazdi, Philippe Menu, Jürg Tschopp. Nature 2011
Rongbin Zhou, Amir S Yazdi, Philippe Menu, Jürg Tschopp. Nature 2011
4
Topology of superoxide production from different sites in the mitochondrial electron transport chain.
Julie St-Pierre, Julie A Buckingham, Stephen J Roebuck, Martin D Brand. J Biol Chem 2002
Julie St-Pierre, Julie A Buckingham, Stephen J Roebuck, Martin D Brand. J Biol Chem 2002
4
Suppressors of Superoxide-H2O2 Production at Site IQ of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury.
Martin D Brand, Renata L S Goncalves, Adam L Orr, Leonardo Vargas, Akos A Gerencser, Martin Borch Jensen, Yves T Wang, Simon Melov, Carolina N Turk, Jason T Matzen,[...]. Cell Metab 2016
Martin D Brand, Renata L S Goncalves, Adam L Orr, Leonardo Vargas, Akos A Gerencser, Martin Borch Jensen, Yves T Wang, Simon Melov, Carolina N Turk, Jason T Matzen,[...]. Cell Metab 2016
4
Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program.
Mireille Khacho, Alysen Clark, Devon S Svoboda, Joelle Azzi, Jason G MacLaurin, Cynthia Meghaizel, Hiromi Sesaki, Diane C Lagace, Marc Germain, Mary-Ellen Harper,[...]. Cell Stem Cell 2016
Mireille Khacho, Alysen Clark, Devon S Svoboda, Joelle Azzi, Jason G MacLaurin, Cynthia Meghaizel, Hiromi Sesaki, Diane C Lagace, Marc Germain, Mary-Ellen Harper,[...]. Cell Stem Cell 2016
4
Fundamental Mechanisms of Regulated Cell Death and Implications for Heart Disease.
Dominic P Del Re, Dulguun Amgalan, Andreas Linkermann, Qinghang Liu, Richard N Kitsis. Physiol Rev 2019
Dominic P Del Re, Dulguun Amgalan, Andreas Linkermann, Qinghang Liu, Richard N Kitsis. Physiol Rev 2019
4
Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction.
Kimberly J Dunham-Snary, Danchen Wu, François Potus, Edward A Sykes, Jeffrey D Mewburn, Rebecca L Charles, Philip Eaton, Richard A Sultanian, Stephen L Archer. Circ Res 2019
Kimberly J Dunham-Snary, Danchen Wu, François Potus, Edward A Sykes, Jeffrey D Mewburn, Rebecca L Charles, Philip Eaton, Richard A Sultanian, Stephen L Archer. Circ Res 2019
11
A rotenone-sensitive site and H2O2 are key components of hypoxia-sensing in neonatal rat adrenomedullary chromaffin cells.
R J Thompson, J Buttigieg, M Zhang, C A Nurse. Neuroscience 2007
R J Thompson, J Buttigieg, M Zhang, C A Nurse. Neuroscience 2007
8
Myocardial ischemia-reperfusion injury: a neglected therapeutic target.
Derek J Hausenloy, Derek M Yellon. J Clin Invest 2013
Derek J Hausenloy, Derek M Yellon. J Clin Invest 2013
4
Reperfusion injury and reactive oxygen species: The evolution of a concept.
D Neil Granger, Peter R Kvietys. Redox Biol 2015
D Neil Granger, Peter R Kvietys. Redox Biol 2015
4
Current Mechanistic Concepts in Ischemia and Reperfusion Injury.
Meng-Yu Wu, Giou-Teng Yiang, Wan-Ting Liao, Andy Po-Yi Tsai, Yeung-Leung Cheng, Pei-Wen Cheng, Chia-Ying Li, Chia-Jung Li. Cell Physiol Biochem 2018
Meng-Yu Wu, Giou-Teng Yiang, Wan-Ting Liao, Andy Po-Yi Tsai, Yeung-Leung Cheng, Pei-Wen Cheng, Chia-Ying Li, Chia-Jung Li. Cell Physiol Biochem 2018
4
Accumulation of succinate controls activation of adipose tissue thermogenesis.
Evanna L Mills, Kerry A Pierce, Mark P Jedrychowski, Ryan Garrity, Sally Winther, Sara Vidoni, Takeshi Yoneshiro, Jessica B Spinelli, Gina Z Lu, Lawrence Kazak,[...]. Nature 2018
Evanna L Mills, Kerry A Pierce, Mark P Jedrychowski, Ryan Garrity, Sally Winther, Sara Vidoni, Takeshi Yoneshiro, Jessica B Spinelli, Gina Z Lu, Lawrence Kazak,[...]. Nature 2018
4
Role of the mitochondrial permeability transition in myocardial disease.
James N Weiss, Paavo Korge, Henry M Honda, Peipei Ping. Circ Res 2003
James N Weiss, Paavo Korge, Henry M Honda, Peipei Ping. Circ Res 2003
4
Production of reactive oxygen species by mitochondria: central role of complex III.
Qun Chen, Edwin J Vazquez, Shadi Moghaddas, Charles L Hoppel, Edward J Lesnefsky. J Biol Chem 2003
Qun Chen, Edwin J Vazquez, Shadi Moghaddas, Charles L Hoppel, Edward J Lesnefsky. J Biol Chem 2003
4
Heart Disease and Stroke Statistics-2021 Update: A Report From the American Heart Association.
Salim S Virani, Alvaro Alonso, Hugo J Aparicio, Emelia J Benjamin, Marcio S Bittencourt, Clifton W Callaway, April P Carson, Alanna M Chamberlain, Susan Cheng, Francesca N Delling,[...]. Circulation 2021
Salim S Virani, Alvaro Alonso, Hugo J Aparicio, Emelia J Benjamin, Marcio S Bittencourt, Clifton W Callaway, April P Carson, Alanna M Chamberlain, Susan Cheng, Francesca N Delling,[...]. Circulation 2021
4
Unraveling the biological roles of reactive oxygen species.
Michael P Murphy, Arne Holmgren, Nils-Göran Larsson, Barry Halliwell, Christopher J Chang, Balaraman Kalyanaraman, Sue Goo Rhee, Paul J Thornalley, Linda Partridge, David Gems,[...]. Cell Metab 2011
Michael P Murphy, Arne Holmgren, Nils-Göran Larsson, Barry Halliwell, Christopher J Chang, Balaraman Kalyanaraman, Sue Goo Rhee, Paul J Thornalley, Linda Partridge, David Gems,[...]. Cell Metab 2011
4
Atomic structure of the entire mammalian mitochondrial complex I.
Karol Fiedorczuk, James A Letts, Gianluca Degliesposti, Karol Kaszuba, Mark Skehel, Leonid A Sazanov. Nature 2016
Karol Fiedorczuk, James A Letts, Gianluca Degliesposti, Karol Kaszuba, Mark Skehel, Leonid A Sazanov. Nature 2016
4
The coupling mechanism of mammalian respiratory complex I.
Domen Kampjut, Leonid A Sazanov. Science 2020
Domen Kampjut, Leonid A Sazanov. Science 2020
8
Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy.
Ming Chen, Ziheng Chen, Yueying Wang, Zheng Tan, Chongzhuo Zhu, Yanjun Li, Zhe Han, Linbo Chen, Ruize Gao, Lei Liu,[...]. Autophagy 2016
Ming Chen, Ziheng Chen, Yueying Wang, Zheng Tan, Chongzhuo Zhu, Yanjun Li, Zhe Han, Linbo Chen, Ruize Gao, Lei Liu,[...]. Autophagy 2016
4
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.