A citation-based method for searching scientific literature

Joseph Ochaba, Tamás Lukacsovich, George Csikos, Shuqiu Zheng, Julia Margulis, Lisa Salazar, Kai Mao, Alice L Lau, Sylvia Y Yeung, Sandrine Humbert, Frédéric Saudou, Daniel J Klionsky, Steven Finkbeiner, Scott O Zeitlin, J Lawrence Marsh, David E Housman, Leslie M Thompson, Joan S Steffan. Proc Natl Acad Sci U S A 2014
Times Cited: 166







List of co-cited articles
3065 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Huntingtin functions as a scaffold for selective macroautophagy.
Yan-Ning Rui, Zhen Xu, Bindi Patel, Zhihua Chen, Dongsheng Chen, Antonio Tito, Gabriela David, Yamin Sun, Erin F Stimming, Hugo J Bellen,[...]. Nat Cell Biol 2015
250
67

Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease.
Marta Martinez-Vicente, Zsolt Talloczy, Esther Wong, Guomei Tang, Hiroshi Koga, Susmita Kaushik, Rosa de Vries, Esperanza Arias, Spike Harris, David Sulzer,[...]. Nat Neurosci 2010
554
51


Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease.
Brinda Ravikumar, Coralie Vacher, Zdenek Berger, Janet E Davies, Shouqing Luo, Lourdes G Oroz, Francesco Scaravilli, Douglas F Easton, Rainer Duden, Cahir J O'Kane,[...]. Nat Genet 2004
28

Autophagy in Huntington disease and huntingtin in autophagy.
Dale D O Martin, Safia Ladha, Dagmar E Ehrnhoefer, Michael R Hayden. Trends Neurosci 2015
179
27


The Biology of Huntingtin.
Frédéric Saudou, Sandrine Humbert. Neuron 2016
388
24

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice.
Taichi Hara, Kenji Nakamura, Makoto Matsui, Akitsugu Yamamoto, Yohko Nakahara, Rika Suzuki-Migishima, Minesuke Yokoyama, Kenji Mishima, Ichiro Saito, Hideyuki Okano,[...]. Nature 2006
24

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
23

Loss of autophagy in the central nervous system causes neurodegeneration in mice.
Masaaki Komatsu, Satoshi Waguri, Tomoki Chiba, Shigeo Murata, Jun-ichi Iwata, Isei Tanida, Takashi Ueno, Masato Koike, Yasuo Uchiyama, Eiki Kominami,[...]. Nature 2006
21

Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease.
Barry Boland, Asok Kumar, Sooyeon Lee, Frances M Platt, Jerzy Wegiel, W Haung Yu, Ralph A Nixon. J Neurosci 2008
773
20

Huntington's disease: from molecular pathogenesis to clinical treatment.
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
933
20

Trehalose alleviates polyglutamine-mediated pathology in a mouse model of Huntington disease.
Motomasa Tanaka, Yoko Machida, Sanyong Niu, Tetsurou Ikeda, Nihar R Jana, Hiroshi Doi, Masaru Kurosawa, Munenori Nekooki, Nobuyuki Nukina. Nat Med 2004
530
19

Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy.
Brinda Ravikumar, Rainer Duden, David C Rubinsztein. Hum Mol Genet 2002
841
19

Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules.
Laurent R Gauthier, Bénédicte C Charrin, Maria Borrell-Pagès, Jim P Dompierre, Hélène Rangone, Fabrice P Cordelières, Jan De Mey, Marcy E MacDonald, Volkmar Lessmann, Sandrine Humbert,[...]. Cell 2004
791
18

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy.
Michael Lazarou, Danielle A Sliter, Lesley A Kane, Shireen A Sarraf, Chunxin Wang, Jonathon L Burman, Dionisia P Sideris, Adam I Fogel, Richard J Youle. Nature 2015
18

Novel targets for Huntington's disease in an mTOR-independent autophagy pathway.
Andrea Williams, Sovan Sarkar, Paul Cuddon, Evangelia K Ttofi, Shinji Saiki, Farah H Siddiqi, Luca Jahreiss, Angeleen Fleming, Dean Pask, Paul Goldsmith,[...]. Nat Chem Biol 2008
594
18

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
17

TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity.
Mickael Decressac, Bengt Mattsson, Pia Weikop, Martin Lundblad, Johan Jakobsson, Anders Björklund. Proc Natl Acad Sci U S A 2013
444
17

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy.
Serhiy Pankiv, Terje Høyvarde Clausen, Trond Lamark, Andreas Brech, Jack-Ansgar Bruun, Heidi Outzen, Aud Øvervatn, Geir Bjørkøy, Terje Johansen. J Biol Chem 2007
17

Polyglutamine tracts regulate beclin 1-dependent autophagy.
Avraham Ashkenazi, Carla F Bento, Thomas Ricketts, Mariella Vicinanza, Farah Siddiqi, Mariana Pavel, Ferdinando Squitieri, Maarten C Hardenberg, Sara Imarisio, Fiona M Menzies,[...]. Nature 2017
191
16

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy.
Ana Maria Cuervo, Leonidas Stefanis, Ross Fredenburg, Peter T Lansbury, David Sulzer. Science 2004
16

The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy.
Maria Filimonenko, Pauline Isakson, Kim D Finley, Monique Anderson, Hyun Jeong, Thomas J Melia, Bryan J Bartlett, Katherine M Myers, Hanne C G Birkeland, Trond Lamark,[...]. Mol Cell 2010
308
16

Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations.
Ju-Hyun Lee, W Haung Yu, Asok Kumar, Sooyeon Lee, Panaiyur S Mohan, Corrinne M Peterhoff, Devin M Wolfe, Marta Martinez-Vicente, Ashish C Massey, Guy Sovak,[...]. Cell 2010
769
15

α-Synuclein impairs macroautophagy: implications for Parkinson's disease.
Ashley R Winslow, Chien-Wen Chen, Silvia Corrochano, Abraham Acevedo-Arozena, David E Gordon, Andrew A Peden, Maike Lichtenberg, Fiona M Menzies, Brinda Ravikumar, Sara Imarisio,[...]. J Cell Biol 2010
526
15

Deletion of the huntingtin polyglutamine stretch enhances neuronal autophagy and longevity in mice.
Shuqiu Zheng, Erin B D Clabough, Sovan Sarkar, Marie Futter, David C Rubinsztein, Scott O Zeitlin. PLoS Genet 2010
107
15

Rhes, a striatal-selective protein implicated in Huntington disease, binds beclin-1 and activates autophagy.
Robert G Mealer, Alexandra J Murray, Neelam Shahani, Srinivasa Subramaniam, Solomon H Snyder. J Biol Chem 2014
84
17


Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities.
Fiona M Menzies, Angeleen Fleming, Andrea Caricasole, Carla F Bento, Stephen P Andrews, Avraham Ashkenazi, Jens Füllgrabe, Anne Jackson, Maria Jimenez Sanchez, Cansu Karabiyik,[...]. Neuron 2017
558
15

IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome.
Leslie Michels Thompson, Charity T Aiken, Linda S Kaltenbach, Namita Agrawal, Katalin Illes, Ali Khoshnan, Marta Martinez-Vincente, Montserrat Arrasate, Jacqueline Gire O'Rourke, Hasan Khashwji,[...]. J Cell Biol 2009
255
14

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death.
Montserrat Arrasate, Siddhartha Mitra, Erik S Schweitzer, Mark R Segal, Steven Finkbeiner. Nature 2004
14

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
14

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death.
Geir Bjørkøy, Trond Lamark, Andreas Brech, Heidi Outzen, Maria Perander, Aud Overvatn, Harald Stenmark, Terje Johansen. J Cell Biol 2005
14

Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity.
Randy Singh Atwal, Jianrun Xia, Deborah Pinchev, Jillian Taylor, Richard M Epand, Ray Truant. Hum Mol Genet 2007
263
13

PGC-1α rescues Huntington's disease proteotoxicity by preventing oxidative stress and promoting TFEB function.
Taiji Tsunemi, Travis D Ashe, Bradley E Morrison, Kathryn R Soriano, Jonathan Au, Ruben A Vázquez Roque, Eduardo R Lazarowski, Vincent A Damian, Eliezer Masliah, Albert R La Spada. Sci Transl Med 2012
302
13

Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity.
Wenjun Song, Jin Chen, Alejandra Petrilli, Geraldine Liot, Eva Klinglmayr, Yue Zhou, Patrick Poquiz, Jonathan Tjong, Mahmoud A Pouladi, Michael R Hayden,[...]. Nat Med 2011
369
13

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.
Joungmok Kim, Mondira Kundu, Benoit Viollet, Kun-Liang Guan. Nat Cell Biol 2011
13

The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice.
Fiona Pickford, Eliezer Masliah, Markus Britschgi, Kurt Lucin, Ramya Narasimhan, Philipp A Jaeger, Scott Small, Brian Spencer, Edward Rockenstein, Beth Levine,[...]. J Clin Invest 2008
785
13

Aβ secretion and plaque formation depend on autophagy.
Per Nilsson, Krishnapriya Loganathan, Misaki Sekiguchi, Yukio Matsuba, Kelvin Hui, Satoshi Tsubuki, Motomasa Tanaka, Nobuhisa Iwata, Takashi Saito, Takaomi C Saido. Cell Rep 2013
279
13

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Daniel J Klionsky, Kotb Abdelmohsen, Akihisa Abe, Md Joynal Abedin, Hagai Abeliovich, Abraham Acevedo Arozena, Hiroaki Adachi, Christopher M Adams, Peter D Adams, Khosrow Adeli,[...]. Autophagy 2016
13


Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates.
Jelena Korac, Veronique Schaeffer, Igor Kovacevic, Albrecht M Clement, Benno Jungblut, Christian Behl, Janos Terzic, Ivan Dikic. J Cell Sci 2013
213
13

Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study.
Ralph A Nixon, Jerzy Wegiel, Asok Kumar, Wai Haung Yu, Corrinne Peterhoff, Anne Cataldo, Ana Maria Cuervo. J Neuropathol Exp Neurol 2005
13

Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease.
Patricia Spilman, Natalia Podlutskaya, Matthew J Hart, Jayanta Debnath, Olivia Gorostiza, Dale Bredesen, Arlan Richardson, Randy Strong, Veronica Galvan. PLoS One 2010
689
13


Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.
Sovan Sarkar, Janet E Davies, Zebo Huang, Alan Tunnacliffe, David C Rubinsztein. J Biol Chem 2007
779
12


VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease.
Xing Guo, XiaoYan Sun, Di Hu, Ya-Juan Wang, Hisashi Fujioka, Rajan Vyas, Sudha Chakrapani, Amit Umesh Joshi, Yu Luo, Daria Mochly-Rosen,[...]. Nat Commun 2016
93
12

TBK-1 promotes autophagy-mediated antimicrobial defense by controlling autophagosome maturation.
Manohar Pilli, John Arko-Mensah, Marisa Ponpuak, Esteban Roberts, Sharon Master, Michael A Mandell, Nicolas Dupont, Wojciech Ornatowski, Shanya Jiang, Steven B Bradfute,[...]. Immunity 2012
417
12

Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria.
Benjamin Richter, Danielle A Sliter, Lina Herhaus, Alexandra Stolz, Chunxin Wang, Petra Beli, Gabriele Zaffagnini, Philipp Wild, Sascha Martens, Sebastian A Wagner,[...]. Proc Natl Acad Sci U S A 2016
392
12


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.