Martin Bachman, Santiago Uribe-Lewis, Xiaoping Yang, Michael Williams, Adele Murrell, Shankar Balasubramanian. Nat Chem 2014
Times Cited: 300
Times Cited: 300
Times Cited
Times Co-cited
Similarity
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1.
Mamta Tahiliani, Kian Peng Koh, Yinghua Shen, William A Pastor, Hozefa Bandukwala, Yevgeny Brudno, Suneet Agarwal, Lakshminarayan M Iyer, David R Liu, L Aravind,[...]. Science 2009
Mamta Tahiliani, Kian Peng Koh, Yinghua Shen, William A Pastor, Hozefa Bandukwala, Yevgeny Brudno, Suneet Agarwal, Lakshminarayan M Iyer, David R Liu, L Aravind,[...]. Science 2009
52
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine.
Shinsuke Ito, Li Shen, Qing Dai, Susan C Wu, Leonard B Collins, James A Swenberg, Chuan He, Yi Zhang. Science 2011
Shinsuke Ito, Li Shen, Qing Dai, Susan C Wu, Leonard B Collins, James A Swenberg, Chuan He, Yi Zhang. Science 2011
45
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA.
Yu-Fei He, Bin-Zhong Li, Zheng Li, Peng Liu, Yang Wang, Qingyu Tang, Jianping Ding, Yingying Jia, Zhangcheng Chen, Lin Li,[...]. Science 2011
Yu-Fei He, Bin-Zhong Li, Zheng Li, Peng Liu, Yang Wang, Qingyu Tang, Jianping Ding, Yingying Jia, Zhangcheng Chen, Lin Li,[...]. Science 2011
33
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain.
Skirmantas Kriaucionis, Nathaniel Heintz. Science 2009
Skirmantas Kriaucionis, Nathaniel Heintz. Science 2009
32
Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives.
Cornelia G Spruijt, Felix Gnerlich, Arne H Smits, Toni Pfaffeneder, Pascal W T C Jansen, Christina Bauer, Martin Münzel, Mirko Wagner, Markus Müller, Fariha Khan,[...]. Cell 2013
Cornelia G Spruijt, Felix Gnerlich, Arne H Smits, Toni Pfaffeneder, Pascal W T C Jansen, Christina Bauer, Martin Münzel, Mirko Wagner, Markus Müller, Fariha Khan,[...]. Cell 2013
26
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification.
Shinsuke Ito, Ana C D'Alessio, Olena V Taranova, Kwonho Hong, Lawrence C Sowers, Yi Zhang. Nature 2010
Shinsuke Ito, Ana C D'Alessio, Olena V Taranova, Kwonho Hong, Lawrence C Sowers, Yi Zhang. Nature 2010
22
Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates.
Daniel Globisch, Martin Münzel, Markus Müller, Stylianos Michalakis, Mirko Wagner, Susanne Koch, Tobias Brückl, Martin Biel, Thomas Carell. PLoS One 2010
Daniel Globisch, Martin Münzel, Markus Müller, Stylianos Michalakis, Mirko Wagner, Susanne Koch, Tobias Brückl, Martin Biel, Thomas Carell. PLoS One 2010
20
Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers.
Michael C Haffner, Alcides Chaux, Alan K Meeker, David M Esopi, Jonathan Gerber, Laxmi G Pellakuru, Antoun Toubaji, Pedram Argani, Christine Iacobuzio-Donahue, William G Nelson,[...]. Oncotarget 2011
Michael C Haffner, Alcides Chaux, Alan K Meeker, David M Esopi, Jonathan Gerber, Laxmi G Pellakuru, Antoun Toubaji, Pedram Argani, Christine Iacobuzio-Donahue, William G Nelson,[...]. Oncotarget 2011
19
5-Formylcytosine can be a stable DNA modification in mammals.
Martin Bachman, Santiago Uribe-Lewis, Xiaoping Yang, Heather E Burgess, Mario Iurlaro, Wolf Reik, Adele Murrell, Shankar Balasubramanian. Nat Chem Biol 2015
Martin Bachman, Santiago Uribe-Lewis, Xiaoping Yang, Heather E Burgess, Mario Iurlaro, Wolf Reik, Adele Murrell, Shankar Balasubramanian. Nat Chem Biol 2015
19
Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine.
Chun-Xiao Song, Keith E Szulwach, Ye Fu, Qing Dai, Chengqi Yi, Xuekun Li, Yujing Li, Chih-Hsin Chen, Wen Zhang, Xing Jian,[...]. Nat Biotechnol 2011
Chun-Xiao Song, Keith E Szulwach, Ye Fu, Qing Dai, Chengqi Yi, Xuekun Li, Yujing Li, Chih-Hsin Chen, Wen Zhang, Xing Jian,[...]. Nat Biotechnol 2011
19
TET-mediated active DNA demethylation: mechanism, function and beyond.
Xiaoji Wu, Yi Zhang. Nat Rev Genet 2017
Xiaoji Wu, Yi Zhang. Nat Rev Genet 2017
17
A screen for hydroxymethylcytosine and formylcytosine binding proteins suggests functions in transcription and chromatin regulation.
Mario Iurlaro, Gabriella Ficz, David Oxley, Eun-Ang Raiber, Martin Bachman, Michael J Booth, Simon Andrews, Shankar Balasubramanian, Wolf Reik. Genome Biol 2013
Mario Iurlaro, Gabriella Ficz, David Oxley, Eun-Ang Raiber, Martin Bachman, Michael J Booth, Simon Andrews, Shankar Balasubramanian, Wolf Reik. Genome Biol 2013
16
MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system.
Marian Mellén, Pinar Ayata, Scott Dewell, Skirmantas Kriaucionis, Nathaniel Heintz. Cell 2012
Marian Mellén, Pinar Ayata, Scott Dewell, Skirmantas Kriaucionis, Nathaniel Heintz. Cell 2012
15
14
5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations.
Seung-Gi Jin, Yong Jiang, Runxiang Qiu, Tibor A Rauch, Yinsheng Wang, Gabriele Schackert, Dietmar Krex, Qiang Lu, Gerd P Pfeifer. Cancer Res 2011
Seung-Gi Jin, Yong Jiang, Runxiang Qiu, Tibor A Rauch, Yinsheng Wang, Gabriele Schackert, Dietmar Krex, Qiang Lu, Gerd P Pfeifer. Cancer Res 2011
13
5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging.
Keith E Szulwach, Xuekun Li, Yujing Li, Chun-Xiao Song, Hao Wu, Qing Dai, Hasan Irier, Anup K Upadhyay, Marla Gearing, Allan I Levey,[...]. Nat Neurosci 2011
Keith E Szulwach, Xuekun Li, Yujing Li, Chun-Xiao Song, Hao Wu, Qing Dai, Hasan Irier, Anup K Upadhyay, Marla Gearing, Allan I Levey,[...]. Nat Neurosci 2011
13
5-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages.
Chun-Xiao Song, Senlin Yin, Li Ma, Amanda Wheeler, Yu Chen, Yan Zhang, Bin Liu, Junjie Xiong, Weihan Zhang, Jiankun Hu,[...]. Cell Res 2017
Chun-Xiao Song, Senlin Yin, Li Ma, Amanda Wheeler, Yu Chen, Yan Zhang, Bin Liu, Junjie Xiong, Weihan Zhang, Jiankun Hu,[...]. Cell Res 2017
13
Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome.
Miao Yu, Gary C Hon, Keith E Szulwach, Chun-Xiao Song, Liang Zhang, Audrey Kim, Xuekun Li, Qing Dai, Yin Shen, Beomseok Park,[...]. Cell 2012
Miao Yu, Gary C Hon, Keith E Szulwach, Chun-Xiao Song, Liang Zhang, Audrey Kim, Xuekun Li, Qing Dai, Yin Shen, Beomseok Park,[...]. Cell 2012
13
Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes.
Colm E Nestor, Raffaele Ottaviano, James Reddington, Duncan Sproul, Diana Reinhardt, Donncha Dunican, Elad Katz, J Michael Dixon, David J Harrison, Richard R Meehan. Genome Res 2012
Colm E Nestor, Raffaele Ottaviano, James Reddington, Duncan Sproul, Diana Reinhardt, Donncha Dunican, Elad Katz, J Michael Dixon, David J Harrison, Richard R Meehan. Genome Res 2012
12
Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma.
Christine Guo Lian, Yufei Xu, Craig Ceol, Feizhen Wu, Allison Larson, Karen Dresser, Wenqi Xu, Li Tan, Yeguang Hu, Qian Zhan,[...]. Cell 2012
Christine Guo Lian, Yufei Xu, Craig Ceol, Feizhen Wu, Allison Larson, Karen Dresser, Wenqi Xu, Li Tan, Yeguang Hu, Qian Zhan,[...]. Cell 2012
12
DNA methylation: roles in mammalian development.
Zachary D Smith, Alexander Meissner. Nat Rev Genet 2013
Zachary D Smith, Alexander Meissner. Nat Rev Genet 2013
12
Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites.
Atanu Maiti, Alexander C Drohat. J Biol Chem 2011
Atanu Maiti, Alexander C Drohat. J Biol Chem 2011
12
Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells.
Hao Wu, Ana C D'Alessio, Shinsuke Ito, Zhibin Wang, Kairong Cui, Keji Zhao, Yi Eve Sun, Yi Zhang. Genes Dev 2011
Hao Wu, Ana C D'Alessio, Shinsuke Ito, Zhibin Wang, Kairong Cui, Keji Zhao, Yi Eve Sun, Yi Zhang. Genes Dev 2011
12
Role of TET enzymes in DNA methylation, development, and cancer.
Kasper Dindler Rasmussen, Kristian Helin. Genes Dev 2016
Kasper Dindler Rasmussen, Kristian Helin. Genes Dev 2016
12
Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation.
H Yang, Y Liu, F Bai, J-Y Zhang, S-H Ma, J Liu, Z-D Xu, H-G Zhu, Z-Q Ling, D Ye,[...]. Oncogene 2013
H Yang, Y Liu, F Bai, J-Y Zhang, S-H Ma, J Liu, Z-D Xu, H-G Zhu, Z-Q Ling, D Ye,[...]. Oncogene 2013
11
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells.
William A Pastor, Utz J Pape, Yun Huang, Hope R Henderson, Ryan Lister, Myunggon Ko, Erin M McLoughlin, Yevgeny Brudno, Sahasransu Mahapatra, Philipp Kapranov,[...]. Nature 2011
William A Pastor, Utz J Pape, Yun Huang, Hope R Henderson, Ryan Lister, Myunggon Ko, Erin M McLoughlin, Yevgeny Brudno, Sahasransu Mahapatra, Philipp Kapranov,[...]. Nature 2011
11
Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation.
Gabriella Ficz, Miguel R Branco, Stefanie Seisenberger, Fátima Santos, Felix Krueger, Timothy A Hore, C Joana Marques, Simon Andrews, Wolf Reik. Nature 2011
Gabriella Ficz, Miguel R Branco, Stefanie Seisenberger, Fátima Santos, Felix Krueger, Timothy A Hore, C Joana Marques, Simon Andrews, Wolf Reik. Nature 2011
11
5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells.
Hume Stroud, Suhua Feng, Shannon Morey Kinney, Sriharsa Pradhan, Steven E Jacobsen. Genome Biol 2011
Hume Stroud, Suhua Feng, Shannon Morey Kinney, Sriharsa Pradhan, Steven E Jacobsen. Genome Biol 2011
11
Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation.
Hideharu Hashimoto, Yiwei Liu, Anup K Upadhyay, Yanqi Chang, Shelley B Howerton, Paula M Vertino, Xing Zhang, Xiaodong Cheng. Nucleic Acids Res 2012
Hideharu Hashimoto, Yiwei Liu, Anup K Upadhyay, Yanqi Chang, Shelley B Howerton, Paula M Vertino, Xing Zhang, Xiaodong Cheng. Nucleic Acids Res 2012
11
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases.
Wei Xu, Hui Yang, Ying Liu, Ying Yang, Ping Wang, Se-Hee Kim, Shinsuke Ito, Chen Yang, Pu Wang, Meng-Tao Xiao,[...]. Cancer Cell 2011
Wei Xu, Hui Yang, Ying Liu, Ying Yang, Ping Wang, Se-Hee Kim, Shinsuke Ito, Chen Yang, Pu Wang, Meng-Tao Xiao,[...]. Cancer Cell 2011
10
5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers.
Wenshuai Li, Xu Zhang, Xingyu Lu, Lei You, Yanqun Song, Zhongguang Luo, Jun Zhang, Ji Nie, Wanwei Zheng, Diannan Xu,[...]. Cell Res 2017
Wenshuai Li, Xu Zhang, Xingyu Lu, Lei You, Yanqun Song, Zhongguang Luo, Jun Zhang, Ji Nie, Wanwei Zheng, Diannan Xu,[...]. Cell Res 2017
10
Nondestructive, base-resolution sequencing of 5-hydroxymethylcytosine using a DNA deaminase.
Emily K Schutsky, Jamie E DeNizio, Peng Hu, Monica Yun Liu, Christopher S Nabel, Emily B Fabyanic, Young Hwang, Frederic D Bushman, Hao Wu, Rahul M Kohli. Nat Biotechnol 2018
Emily K Schutsky, Jamie E DeNizio, Peng Hu, Monica Yun Liu, Christopher S Nabel, Emily B Fabyanic, Young Hwang, Frederic D Bushman, Hao Wu, Rahul M Kohli. Nat Biotechnol 2018
13
The discovery of 5-formylcytosine in embryonic stem cell DNA.
Toni Pfaffeneder, Benjamin Hackner, Matthias Truss, Martin Münzel, Markus Müller, Christian A Deiml, Christian Hagemeier, Thomas Carell. Angew Chem Int Ed Engl 2011
Toni Pfaffeneder, Benjamin Hackner, Matthias Truss, Martin Münzel, Markus Müller, Christian A Deiml, Christian Hagemeier, Thomas Carell. Angew Chem Int Ed Engl 2011
9
Oxidative bisulfite sequencing of 5-methylcytosine and 5-hydroxymethylcytosine.
Michael J Booth, Tobias W B Ost, Dario Beraldi, Neil M Bell, Miguel R Branco, Wolf Reik, Shankar Balasubramanian. Nat Protoc 2013
Michael J Booth, Tobias W B Ost, Dario Beraldi, Neil M Bell, Miguel R Branco, Wolf Reik, Shankar Balasubramanian. Nat Protoc 2013
9
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.
Kelly Moran-Crusio, Linsey Reavie, Alan Shih, Omar Abdel-Wahab, Delphine Ndiaye-Lobry, Camille Lobry, Maria E Figueroa, Aparna Vasanthakumar, Jay Patel, Xinyang Zhao,[...]. Cancer Cell 2011
Kelly Moran-Crusio, Linsey Reavie, Alan Shih, Omar Abdel-Wahab, Delphine Ndiaye-Lobry, Camille Lobry, Maria E Figueroa, Aparna Vasanthakumar, Jay Patel, Xinyang Zhao,[...]. Cancer Cell 2011
9
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity.
Kristine Williams, Jesper Christensen, Marianne Terndrup Pedersen, Jens V Johansen, Paul A C Cloos, Juri Rappsilber, Kristian Helin. Nature 2011
Kristine Williams, Jesper Christensen, Marianne Terndrup Pedersen, Jens V Johansen, Paul A C Cloos, Juri Rappsilber, Kristian Helin. Nature 2011
9
Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids.
Lakshminarayan M Iyer, Mamta Tahiliani, Anjana Rao, L Aravind. Cell Cycle 2009
Lakshminarayan M Iyer, Mamta Tahiliani, Anjana Rao, L Aravind. Cell Cycle 2009
9
The diverse roles of DNA methylation in mammalian development and disease.
Maxim V C Greenberg, Deborah Bourc'his. Nat Rev Mol Cell Biol 2019
Maxim V C Greenberg, Deborah Bourc'his. Nat Rev Mol Cell Biol 2019
9
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX.
Myunggon Ko, Jungeun An, Hozefa S Bandukwala, Lukas Chavez, Tarmo Aijö, William A Pastor, Matthew F Segal, Huiming Li, Kian Peng Koh, Harri Lähdesmäki,[...]. Nature 2013
Myunggon Ko, Jungeun An, Hozefa S Bandukwala, Lukas Chavez, Tarmo Aijö, William A Pastor, Matthew F Segal, Huiming Li, Kian Peng Koh, Harri Lähdesmäki,[...]. Nature 2013
9
Human DNA methylomes at base resolution show widespread epigenomic differences.
Ryan Lister, Mattia Pelizzola, Robert H Dowen, R David Hawkins, Gary Hon, Julian Tonti-Filippini, Joseph R Nery, Leonard Lee, Zhen Ye, Que-Minh Ngo,[...]. Nature 2009
Ryan Lister, Mattia Pelizzola, Robert H Dowen, R David Hawkins, Gary Hon, Julian Tonti-Filippini, Joseph R Nery, Leonard Lee, Zhen Ye, Que-Minh Ngo,[...]. Nature 2009
9
Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression.
Luisa Cimmino, Igor Dolgalev, Yubao Wang, Akihide Yoshimi, Gaëlle H Martin, Jingjing Wang, Victor Ng, Bo Xia, Matthew T Witkowski, Marisa Mitchell-Flack,[...]. Cell 2017
Luisa Cimmino, Igor Dolgalev, Yubao Wang, Akihide Yoshimi, Gaëlle H Martin, Jingjing Wang, Victor Ng, Bo Xia, Matthew T Witkowski, Marisa Mitchell-Flack,[...]. Cell 2017
8
Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution.
Michael J Booth, Miguel R Branco, Gabriella Ficz, David Oxley, Felix Krueger, Wolf Reik, Shankar Balasubramanian. Science 2012
Michael J Booth, Miguel R Branco, Gabriella Ficz, David Oxley, Felix Krueger, Wolf Reik, Shankar Balasubramanian. Science 2012
8
Effects of cytosine modifications on DNA flexibility and nucleosome mechanical stability.
Thuy T M Ngo, Jejoong Yoo, Qing Dai, Qiucen Zhang, Chuan He, Aleksei Aksimentiev, Taekjip Ha. Nat Commun 2016
Thuy T M Ngo, Jejoong Yoo, Qing Dai, Qiucen Zhang, Chuan He, Aleksei Aksimentiev, Taekjip Ha. Nat Commun 2016
8
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2.
Myunggon Ko, Yun Huang, Anna M Jankowska, Utz J Pape, Mamta Tahiliani, Hozefa S Bandukwala, Jungeun An, Edward D Lamperti, Kian Peng Koh, Rebecca Ganetzky,[...]. Nature 2010
Myunggon Ko, Yun Huang, Anna M Jankowska, Utz J Pape, Mamta Tahiliani, Hozefa S Bandukwala, Jungeun An, Edward D Lamperti, Kian Peng Koh, Rebecca Ganetzky,[...]. Nature 2010
8
Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics.
Li Shen, Hao Wu, Dinh Diep, Shinpei Yamaguchi, Ana C D'Alessio, Ho-Lim Fung, Kun Zhang, Yi Zhang. Cell 2013
Li Shen, Hao Wu, Dinh Diep, Shinpei Yamaguchi, Ana C D'Alessio, Ho-Lim Fung, Kun Zhang, Yi Zhang. Cell 2013
8
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes.
Tian-Peng Gu, Fan Guo, Hui Yang, Hai-Ping Wu, Gui-Fang Xu, Wei Liu, Zhi-Guo Xie, Linyu Shi, Xinyi He, Seung-gi Jin,[...]. Nature 2011
Tian-Peng Gu, Fan Guo, Hui Yang, Hai-Ping Wu, Gui-Fang Xu, Wei Liu, Zhi-Guo Xie, Linyu Shi, Xinyi He, Seung-gi Jin,[...]. Nature 2011
8
Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA.
Toni Pfaffeneder, Fabio Spada, Mirko Wagner, Caterina Brandmayr, Silvia K Laube, David Eisen, Matthias Truss, Jessica Steinbacher, Benjamin Hackner, Olga Kotljarova,[...]. Nat Chem Biol 2014
Toni Pfaffeneder, Fabio Spada, Mirko Wagner, Caterina Brandmayr, Silvia K Laube, David Eisen, Matthias Truss, Jessica Steinbacher, Benjamin Hackner, Olga Kotljarova,[...]. Nat Chem Biol 2014
8
Structural insight into substrate preference for TET-mediated oxidation.
Lulu Hu, Junyan Lu, Jingdong Cheng, Qinhui Rao, Ze Li, Haifeng Hou, Zhiyong Lou, Lei Zhang, Wei Li, Wei Gong,[...]. Nature 2015
Lulu Hu, Junyan Lu, Jingdong Cheng, Qinhui Rao, Ze Li, Haifeng Hou, Zhiyong Lou, Lei Zhang, Wei Li, Wei Gong,[...]. Nature 2015
8
Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism.
Alain R Weber, Claudia Krawczyk, Adam B Robertson, Anna Kuśnierczyk, Cathrine B Vågbø, David Schuermann, Arne Klungland, Primo Schär. Nat Commun 2016
Alain R Weber, Claudia Krawczyk, Adam B Robertson, Anna Kuśnierczyk, Cathrine B Vågbø, David Schuermann, Arne Klungland, Primo Schär. Nat Commun 2016
8
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.