A citation-based method for searching scientific literature

Edmond Chipumuro, Eugenio Marco, Camilla L Christensen, Nicholas Kwiatkowski, Tinghu Zhang, Clark M Hatheway, Brian J Abraham, Bandana Sharma, Caleb Yeung, Abigail Altabef, Antonio Perez-Atayde, Kwok-Kin Wong, Guo-Cheng Yuan, Nathanael S Gray, Richard A Young, Rani E George. Cell 2014
Times Cited: 366







List of co-cited articles
1198 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Targeting transcription regulation in cancer with a covalent CDK7 inhibitor.
Nicholas Kwiatkowski, Tinghu Zhang, Peter B Rahl, Brian J Abraham, Jessica Reddy, Scott B Ficarro, Anahita Dastur, Arnaud Amzallag, Sridhar Ramaswamy, Bethany Tesar,[...]. Nature 2014
487
54

Targeting transcriptional addictions in small cell lung cancer with a covalent CDK7 inhibitor.
Camilla L Christensen, Nicholas Kwiatkowski, Brian J Abraham, Julian Carretero, Fatima Al-Shahrour, Tinghu Zhang, Edmond Chipumuro, Grit S Herter-Sprie, Esra A Akbay, Abigail Altabef,[...]. Cancer Cell 2014
277
44

Selective inhibition of tumor oncogenes by disruption of super-enhancers.
Jakob Lovén, Heather A Hoke, Charles Y Lin, Ashley Lau, David A Orlando, Christopher R Vakoc, James E Bradner, Tong Ihn Lee, Richard A Young. Cell 2013
41

Super-enhancers in the control of cell identity and disease.
Denes Hnisz, Brian J Abraham, Tong Ihn Lee, Ashley Lau, Violaine Saint-André, Alla A Sigova, Heather A Hoke, Richard A Young. Cell 2013
41

CDK7-dependent transcriptional addiction in triple-negative breast cancer.
Yubao Wang, Tinghu Zhang, Nicholas Kwiatkowski, Brian J Abraham, Tong Ihn Lee, Shaozhen Xie, Haluk Yuzugullu, Thanh Von, Heyuan Li, Ziao Lin,[...]. Cell 2015
255
38

Master transcription factors and mediator establish super-enhancers at key cell identity genes.
Warren A Whyte, David A Orlando, Denes Hnisz, Brian J Abraham, Charles Y Lin, Michael H Kagey, Peter B Rahl, Tong Ihn Lee, Richard A Young. Cell 2013
35

Transcriptional Addiction in Cancer.
James E Bradner, Denes Hnisz, Richard A Young. Cell 2017
492
26

BET bromodomain inhibition as a therapeutic strategy to target c-Myc.
Jake E Delmore, Ghayas C Issa, Madeleine E Lemieux, Peter B Rahl, Junwei Shi, Hannah M Jacobs, Efstathios Kastritis, Timothy Gilpatrick, Ronald M Paranal, Jun Qi,[...]. Cell 2011
26

Discovery and characterization of super-enhancer-associated dependencies in diffuse large B cell lymphoma.
Bjoern Chapuy, Michael R McKeown, Charles Y Lin, Stefano Monti, Margaretha G M Roemer, Jun Qi, Peter B Rahl, Heather H Sun, Kelly T Yeda, John G Doench,[...]. Cancer Cell 2013
484
20

Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II.
Stéphane Larochelle, Ramon Amat, Kira Glover-Cutter, Miriam Sansó, Chao Zhang, Jasmina J Allen, Kevan M Shokat, David L Bentley, Robert P Fisher. Nat Struct Mol Biol 2012
239
18

Coactivator condensation at super-enhancers links phase separation and gene control.
Benjamin R Sabari, Alessandra Dall'Agnese, Ann Boija, Isaac A Klein, Eliot L Coffey, Krishna Shrinivas, Brian J Abraham, Nancy M Hannett, Alicia V Zamudio, John C Manteiga,[...]. Science 2018
881
16

Discovery and Characterization of SY-1365, a Selective, Covalent Inhibitor of CDK7.
Shanhu Hu, Jason J Marineau, Nisha Rajagopal, Kristin B Hamman, Yoon Jong Choi, Darby R Schmidt, Nan Ke, Liv Johannessen, Michael J Bradley, David A Orlando,[...]. Cancer Res 2019
56
28

Development of a Selective CDK7 Covalent Inhibitor Reveals Predominant Cell-Cycle Phenotype.
Calla M Olson, Yanke Liang, Alan Leggett, Woojun D Park, Lianbo Li, Caitlin E Mills, Selma Z Elsarrag, Scott B Ficarro, Tinghu Zhang, Robert Düster,[...]. Cell Chem Biol 2019
57
28

A Phase Separation Model for Transcriptional Control.
Denes Hnisz, Krishna Shrinivas, Richard A Young, Arup K Chakraborty, Phillip A Sharp. Cell 2017
770
15

Transcriptional amplification in tumor cells with elevated c-Myc.
Charles Y Lin, Jakob Lovén, Peter B Rahl, Ronald M Paranal, Christopher B Burge, James E Bradner, Tong Ihn Lee, Richard A Young. Cell 2012
964
15

Targeting MYCN in neuroblastoma by BET bromodomain inhibition.
Alexandre Puissant, Stacey M Frumm, Gabriela Alexe, Christopher F Bassil, Jun Qi, Yvan H Chanthery, Erin A Nekritz, Rhamy Zeid, William Clay Gustafson, Patricia Greninger,[...]. Cancer Discov 2013
421
15

Oncogene regulation. An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element.
Marc R Mansour, Brian J Abraham, Lars Anders, Alla Berezovskaya, Alejandro Gutierrez, Adam D Durbin, Julia Etchin, Lee Lawton, Stephen E Sallan, Lewis B Silverman,[...]. Science 2014
448
15

Targeting super-enhancer-associated oncogenes in oesophageal squamous cell carcinoma.
Yan-Yi Jiang, De-Chen Lin, Anand Mayakonda, Masaharu Hazawa, Ling-Wen Ding, Wen-Wen Chien, Liang Xu, Ye Chen, Jin-Fen Xiao, William Senapedis,[...]. Gut 2017
117
15

CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer.
Hua Zhang, Camilla L Christensen, Ruben Dries, Matthew G Oser, Jiehui Deng, Brian Diskin, Fei Li, Yuanwang Pan, Xuzhu Zhang, Yandong Yin,[...]. Cancer Cell 2020
80
17

Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry.
Adam D Durbin, Mark W Zimmerman, Neekesh V Dharia, Brian J Abraham, Amanda Balboni Iniguez, Nina Weichert-Leahey, Shuning He, John M Krill-Burger, David E Root, Francisca Vazquez,[...]. Nat Genet 2018
95
14

Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors.
Tinghu Zhang, Nicholas Kwiatkowski, Calla M Olson, Sarah E Dixon-Clarke, Brian J Abraham, Ann K Greifenberg, Scott B Ficarro, Jonathan M Elkins, Yanke Liang, Nancy M Hannett,[...]. Nat Chem Biol 2016
158
13

Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains.
Ann Boija, Isaac A Klein, Benjamin R Sabari, Alessandra Dall'Agnese, Eliot L Coffey, Alicia V Zamudio, Charles H Li, Krishna Shrinivas, John C Manteiga, Nancy M Hannett,[...]. Cell 2018
588
13

Selective inhibition of BET bromodomains.
Panagis Filippakopoulos, Jun Qi, Sarah Picaud, Yao Shen, William B Smith, Oleg Fedorov, Elizabeth M Morse, Tracey Keates, Tyler T Hickman, Ildiko Felletar,[...]. Nature 2010
13

Cyclin-dependent kinases.
Marcos Malumbres. Genome Biol 2014
683
12

The Covalent CDK7 Inhibitor THZ1 Potently Induces Apoptosis in Multiple Myeloma Cells In Vitro and In Vivo.
Yu Zhang, Liang Zhou, Dipankar Bandyopadhyay, Kanika Sharma, Alexander Joseph Allen, Maciej Kmieciak, Steven Grant. Clin Cancer Res 2019
27
44

MYC on the path to cancer.
Chi V Dang. Cell 2012
11

ICEC0942, an Orally Bioavailable Selective Inhibitor of CDK7 for Cancer Treatment.
Hetal Patel, Manikandan Periyasamy, Georgina P Sava, Alexander Bondke, Brian W Slafer, Sebastian H B Kroll, Marion Barbazanges, Richard Starkey, Silvia Ottaviani, Alison Harrod,[...]. Mol Cancer Ther 2018
52
21

Targeting MYC dependence in cancer by inhibiting BET bromodomains.
Jennifer A Mertz, Andrew R Conery, Barbara M Bryant, Peter Sandy, Srividya Balasubramanian, Deanna A Mele, Louise Bergeron, Robert J Sims. Proc Natl Acad Sci U S A 2011
802
11

Super-Enhancer-Driven Transcriptional Dependencies in Cancer.
Satyaki Sengupta, Rani E George. Trends Cancer 2017
118
11

Mediator kinase inhibition further activates super-enhancer-associated genes in AML.
Henry E Pelish, Brian B Liau, Ioana I Nitulescu, Anupong Tangpeerachaikul, Zachary C Poss, Diogo H Da Silva, Brittany T Caruso, Alexander Arefolov, Olugbeminiyi Fadeyi, Amanda L Christie,[...]. Nature 2015
221
11

CDK7 inhibitors as anticancer drugs.
Georgina P Sava, Hailing Fan, R Charles Coombes, Lakjaya Buluwela, Simak Ali. Cancer Metastasis Rev 2020
39
28

Convergence of developmental and oncogenic signaling pathways at transcriptional super-enhancers.
Denes Hnisz, Jurian Schuijers, Charles Y Lin, Abraham S Weintraub, Brian J Abraham, Tong Ihn Lee, James E Bradner, Richard A Young. Mol Cell 2015
263
11

What are super-enhancers?
Sebastian Pott, Jason D Lieb. Nat Genet 2015
371
11

Small-molecule targeting of brachyury transcription factor addiction in chordoma.
Tanaz Sharifnia, Mathias J Wawer, Ting Chen, Qing-Yuan Huang, Barbara A Weir, Ann Sizemore, Matthew A Lawlor, Amy Goodale, Glenn S Cowley, Francisca Vazquez,[...]. Nat Med 2019
65
15

CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2.
Liying Chen, Gabriela Alexe, Neekesh V Dharia, Linda Ross, Amanda Balboni Iniguez, Amy Saur Conway, Emily Jue Wang, Veronica Veschi, Norris Lam, Jun Qi,[...]. J Clin Invest 2018
70
14

Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion.
Miguel Ganuza, Cristina Sáiz-Ladera, Marta Cañamero, Gonzalo Gómez, Ralph Schneider, María A Blasco, David Pisano, Jesús M Paramio, David Santamaría, Mariano Barbacid. EMBO J 2012
64
15

Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription.
Jenna K Rimel, Zachary C Poss, Benjamin Erickson, Zachary L Maas, Christopher C Ebmeier, Jared L Johnson, Tim-Michael Decker, Tomer M Yaron, Michael J Bradley, Kristin B Hamman,[...]. Genes Dev 2020
23
43

TFIIH-associated Cdk7 kinase functions in phosphorylation of C-terminal domain Ser7 residues, promoter-proximal pausing, and termination by RNA polymerase II.
Kira Glover-Cutter, Stéphane Larochelle, Benjamin Erickson, Chao Zhang, Kevan Shokat, Robert P Fisher, David L Bentley. Mol Cell Biol 2009
215
9

Targeting MYC dependency in ovarian cancer through inhibition of CDK7 and CDK12/13.
Mei Zeng, Nicholas P Kwiatkowski, Tinghu Zhang, Behnam Nabet, Mousheng Xu, Yanke Liang, Chunshan Quan, Jinhua Wang, Mingfeng Hao, Sangeetha Palakurthi,[...]. Elife 2018
68
13

Mediator and RNA polymerase II clusters associate in transcription-dependent condensates.
Won-Ki Cho, Jan-Hendrik Spille, Micca Hecht, Choongman Lee, Charles Li, Valentin Grube, Ibrahim I Cisse. Science 2018
531
9

Activation of the p53 Transcriptional Program Sensitizes Cancer Cells to Cdk7 Inhibitors.
Sampada Kalan, Ramon Amat, Miriam Merzel Schachter, Nicholas Kwiatkowski, Brian J Abraham, Yanke Liang, Tinghu Zhang, Calla M Olson, Stéphane Larochelle, Richard A Young,[...]. Cell Rep 2017
46
19

Small Molecules Co-targeting CKIα and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models.
Waleed Minzel, Avanthika Venkatachalam, Avner Fink, Eric Hung, Guy Brachya, Ido Burstain, Maya Shaham, Amitai Rivlin, Itay Omer, Adar Zinger,[...]. Cell 2018
70
12

Therapeutic Rationale to Target Highly Expressed CDK7 Conferring Poor Outcomes in Triple-Negative Breast Cancer.
Bo Li, Triona Ni Chonghaile, Yue Fan, Stephen F Madden, Rut Klinger, Aisling E O'Connor, Louise Walsh, Gillian O'Hurley, Girish Mallya Udupi, Jesuchristopher Joseph,[...]. Cancer Res 2017
53
16

Drugging MYCN through an allosteric transition in Aurora kinase A.
William Clay Gustafson, Justin Gabriel Meyerowitz, Erin A Nekritz, Justin Chen, Cyril Benes, Elise Charron, Erin F Simonds, Robert Seeger, Katherine K Matthay, Nicholas T Hertz,[...]. Cancer Cell 2014
169
9

Reflecting on 25 years with MYC.
Natalie Meyer, Linda Z Penn. Nat Rev Cancer 2008
9

Pol II phosphorylation regulates a switch between transcriptional and splicing condensates.
Yang Eric Guo, John C Manteiga, Jonathan E Henninger, Benjamin R Sabari, Alessandra Dall'Agnese, Nancy M Hannett, Jan-Hendrik Spille, Lena K Afeyan, Alicia V Zamudio, Krishna Shrinivas,[...]. Nature 2019
233
9

Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy.
Huiying Han, Atul D Jain, Mihai I Truica, Javier Izquierdo-Ferrer, Jonathan F Anker, Barbara Lysy, Vinay Sagar, Yi Luan, Zachary R Chalmers, Kenji Unno,[...]. Cancer Cell 2019
119
9

Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma.
Jiang Yuan, Yan-Yi Jiang, Anand Mayakonda, Moli Huang, Ling-Wen Ding, Han Lin, Fenggang Yu, Yanan Lu, Thomas Kwok Seng Loh, Marilynn Chow,[...]. Cancer Res 2017
62
14

Transcriptional Dependencies in Diffuse Intrinsic Pontine Glioma.
Surya Nagaraja, Nicholas A Vitanza, Pamelyn J Woo, Kathryn R Taylor, Fang Liu, Lei Zhang, Meng Li, Wei Meng, Anitha Ponnuswami, Wenchao Sun,[...]. Cancer Cell 2017
182
9

Targeting MYCN-Driven Transcription By BET-Bromodomain Inhibition.
Anton Henssen, Kristina Althoff, Andrea Odersky, Anneleen Beckers, Richard Koche, Frank Speleman, Simon Schäfers, Emma Bell, Maike Nortmeyer, Frank Westermann,[...]. Clin Cancer Res 2016
113
9


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.