A citation-based method for searching scientific literature

Marc Foretz, Bruno Guigas, Luc Bertrand, Michael Pollak, Benoit Viollet. Cell Metab 2014
Times Cited: 611







List of co-cited articles
714 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


The mechanisms of action of metformin.
Graham Rena, D Grahame Hardie, Ewan R Pearson. Diabetologia 2017
675
23

Role of AMP-activated protein kinase in mechanism of metformin action.
G Zhou, R Myers, Y Li, Y Chen, X Shen, J Fenyk-Melody, M Wu, J Ventre, T Doebber, N Fujii,[...]. J Clin Invest 2001
15

Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus.
Marc Foretz, Bruno Guigas, Benoit Viollet. Nat Rev Endocrinol 2019
135
12

Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP.
Russell A Miller, Qingwei Chu, Jianxin Xie, Marc Foretz, Benoit Viollet, Morris J Birnbaum. Nature 2013
502
12

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state.
Marc Foretz, Sophie Hébrard, Jocelyne Leclerc, Elham Zarrinpashneh, Maud Soty, Gilles Mithieux, Kei Sakamoto, Fabrizio Andreelli, Benoit Viollet. J Clin Invest 2010
810
12

Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase.
Anila K Madiraju, Derek M Erion, Yasmeen Rahimi, Xian-Man Zhang, Demetrios T Braddock, Ronald A Albright, Brett J Prigaro, John L Wood, Sanjay Bhanot, Michael J MacDonald,[...]. Nature 2014
672
11

The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin.
Reuben J Shaw, Katja A Lamia, Debbie Vasquez, Seung-Hoi Koo, Nabeel Bardeesy, Ronald A Depinho, Marc Montminy, Lewis C Cantley. Science 2005
11

AMPK: a nutrient and energy sensor that maintains energy homeostasis.
D Grahame Hardie, Fiona A Ross, Simon A Hawley. Nat Rev Mol Cell Biol 2012
10

Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.
M Y El-Mir, V Nogueira, E Fontaine, N Avéret, M Rigoulet, X Leverve. J Biol Chem 2000
933
10

Metformin and the gastrointestinal tract.
Laura J McCreight, Clifford J Bailey, Ewan R Pearson. Diabetologia 2016
276
10

Metformin action: concentrations matter.
Ling He, Fredric E Wondisford. Cell Metab 2015
219
10

Metformin Improves Mitochondrial Respiratory Activity through Activation of AMPK.
Yu Wang, Hongying An, Ting Liu, Caolitao Qin, Hiromi Sesaki, Shaodong Guo, Sally Radovick, Mehboob Hussain, Akhil Maheshwari, Fredric E Wondisford,[...]. Cell Rep 2019
77
12


Metformin activates a duodenal Ampk-dependent pathway to lower hepatic glucose production in rats.
Frank A Duca, Clémence D Côté, Brittany A Rasmussen, Melika Zadeh-Tahmasebi, Guy A Rutter, Beatrice M Filippi, Tony K T Lam. Nat Med 2015
219
8

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug.
Hao Wu, Eduardo Esteve, Valentina Tremaroli, Muhammad Tanweer Khan, Robert Caesar, Louise Mannerås-Holm, Marcus Ståhlman, Lisa M Olsson, Matteo Serino, Mercè Planas-Fèlix,[...]. Nat Med 2017
577
8

Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria.
Hannah R Bridges, Andrew J Y Jones, Michael N Pollak, Judy Hirst. Biochem J 2014
364
8

Cellular and molecular mechanisms of metformin: an overview.
Benoit Viollet, Bruno Guigas, Nieves Sanz Garcia, Jocelyne Leclerc, Marc Foretz, Fabrizio Andreelli. Clin Sci (Lond) 2012
964
8

Metformin: clinical use in type 2 diabetes.
Elizabeth Sanchez-Rangel, Silvio E Inzucchi. Diabetologia 2017
126
8

Metformin--mode of action and clinical implications for diabetes and cancer.
Ida Pernicova, Márta Korbonits. Nat Rev Endocrinol 2014
615
7


Metformin Activates AMPK through the Lysosomal Pathway.
Chen-Song Zhang, Mengqi Li, Teng Ma, Yue Zong, Jiwen Cui, Jin-Wei Feng, Yu-Qing Wu, Shu-Yong Lin, Sheng-Cai Lin. Cell Metab 2016
112
7

Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner.
Adem Kalender, Anand Selvaraj, So Young Kim, Pawan Gulati, Sophie Brûlé, Benoit Viollet, Bruce E Kemp, Nabeel Bardeesy, Patrick Dennis, John J Schlager,[...]. Cell Metab 2010
574
7

Metformin: historical overview.
Clifford J Bailey. Diabetologia 2017
243
7


10-year follow-up of intensive glucose control in type 2 diabetes.
Rury R Holman, Sanjoy K Paul, M Angelyn Bethel, David R Matthews, H Andrew W Neil. N Engl J Med 2008
6



Metformin lowers α-synuclein phosphorylation and upregulates neurotrophic factor in the MPTP mouse model of Parkinson's disease.
Nikita Katila, Sunil Bhurtel, Sina Shadfar, Sunil Srivastav, Sabita Neupane, Uttam Ojha, Gil-Saeng Jeong, Dong-Young Choi. Neuropharmacology 2017
64
9

Mechanism by which metformin reduces glucose production in type 2 diabetes.
R S Hundal, M Krssak, S Dufour, D Laurent, V Lebon, V Chandramouli, S E Inzucchi, W C Schumann, K F Petersen, B R Landau,[...]. Diabetes 2000
685
6

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.
Joungmok Kim, Mondira Kundu, Benoit Viollet, Kun-Liang Guan. Nat Cell Biol 2011
6

Role of Mitochondria in the Mechanism(s) of Action of Metformin.
Guillaume Vial, Dominique Detaille, Bruno Guigas. Front Endocrinol (Lausanne) 2019
80
7

AMPK signalling in health and disease.
David Carling. Curr Opin Cell Biol 2017
241
6


Benefits of Metformin in Attenuating the Hallmarks of Aging.
Ameya S Kulkarni, Sriram Gubbi, Nir Barzilai. Cell Metab 2020
92
6

Metformin improves healthspan and lifespan in mice.
Alejandro Martin-Montalvo, Evi M Mercken, Sarah J Mitchell, Hector H Palacios, Patricia L Mote, Morten Scheibye-Knudsen, Ana P Gomes, Theresa M Ward, Robin K Minor, Marie-José Blouin,[...]. Nat Commun 2013
690
6

Metformin pathways: pharmacokinetics and pharmacodynamics.
Li Gong, Srijib Goswami, Kathleen M Giacomini, Russ B Altman, Teri E Klein. Pharmacogenet Genomics 2012
232
6

Metformin and Inflammation: Its Potential Beyond Glucose-lowering Effect.
Yoshifumi Saisho. Endocr Metab Immune Disord Drug Targets 2015
220
6

Clinical pharmacokinetics of metformin.
Garry G Graham, Jeroen Punt, Manit Arora, Richard O Day, Matthew P Doogue, Janna K Duong, Timothy J Furlong, Jerry R Greenfield, Louise C Greenup, Carl M Kirkpatrick,[...]. Clin Pharmacokinet 2011
605
6

Metformin-induced changes of the gut microbiota in healthy young men: results of a non-blinded, one-armed intervention study.
Thomas Bryrup, Cæcilie W Thomsen, Timo Kern, Kristine H Allin, Ivan Brandslund, Niklas R Jørgensen, Henrik Vestergaard, Torben Hansen, Tue H Hansen, Oluf Pedersen,[...]. Diabetologia 2019
58
8

Effects of metformin versus glipizide on cardiovascular outcomes in patients with type 2 diabetes and coronary artery disease.
Jie Hong, Yifei Zhang, Shenghan Lai, Ankang Lv, Qing Su, Yan Dong, Zhiguang Zhou, Weili Tang, Jiajun Zhao, Lianqun Cui,[...]. Diabetes Care 2013
198
5

Low concentrations of metformin suppress glucose production in hepatocytes through AMP-activated protein kinase (AMPK).
Jia Cao, Shumei Meng, Evan Chang, Katherine Beckwith-Fickas, Lishou Xiong, Robert N Cole, Sally Radovick, Fredric E Wondisford, Ling He. J Biol Chem 2014
111
5

Metformin as an adjuvant treatment for cancer: a systematic review and meta-analysis.
C Coyle, F H Cafferty, C Vale, R E Langley. Ann Oncol 2016
172
5

Neuroprotective effect of metformin in MPTP-induced Parkinson's disease in mice.
S P Patil, P D Jain, P J Ghumatkar, R Tambe, S Sathaye. Neuroscience 2014
142
5

Metformin - a Future Therapy for Neurodegenerative Diseases : Theme: Drug Discovery, Development and Delivery in Alzheimer's Disease Guest Editor: Davide Brambilla.
Magdalena Markowicz-Piasecka, Joanna Sikora, Aleksandra Szydłowska, Agata Skupień, Elżbieta Mikiciuk-Olasik, Kristiina M Huttunen. Pharm Res 2017
107
5

The Therapeutic Potential of Metformin in Neurodegenerative Diseases.
Carola Rotermund, Gerrit Machetanz, Julia C Fitzgerald. Front Endocrinol (Lausanne) 2018
100
5


Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin.
Morgan D Fullerton, Sandra Galic, Katarina Marcinko, Sarah Sikkema, Thomas Pulinilkunnil, Zhi-Ping Chen, Hayley M O'Neill, Rebecca J Ford, Rengasamy Palanivel, Matthew O'Brien,[...]. Nat Med 2013
434
5

Metformin in 2019.
James Flory, Kasia Lipska. JAMA 2019
63
7

Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with type 2 diabetes.
Nicolas Musi, Michael F Hirshman, Jonas Nygren, Monika Svanfeldt, Peter Bavenholm, Olav Rooyackers, Gaochao Zhou, Joanne M Williamson, Olle Ljunqvist, Suad Efendic,[...]. Diabetes 2002
564
5

Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin.
William C Knowler, Elizabeth Barrett-Connor, Sarah E Fowler, Richard F Hamman, John M Lachin, Elizabeth A Walker, David M Nathan. N Engl J Med 2002
5


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.