Alberto Ciccia, Jen-Wei Huang, Lior Izhar, Mathew E Sowa, J Wade Harper, Stephen J Elledge. Proc Natl Acad Sci U S A 2014
Times Cited: 69
Times Cited: 69
Times Cited
Times Co-cited
Similarity
The NBS1-Treacle complex controls ribosomal RNA transcription in response to DNA damage.
Dorthe H Larsen, Flurina Hari, Julie A Clapperton, Myriam Gwerder, Katrin Gutsche, Matthias Altmeyer, Stephanie Jungmichel, Luis I Toledo, Daniel Fink, Maj-Britt Rask,[...]. Nat Cell Biol 2014
Dorthe H Larsen, Flurina Hari, Julie A Clapperton, Myriam Gwerder, Katrin Gutsche, Matthias Altmeyer, Stephanie Jungmichel, Luis I Toledo, Daniel Fink, Maj-Britt Rask,[...]. Nat Cell Biol 2014
69
The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks.
Michael Kruhlak, Elizabeth E Crouch, Marika Orlov, Carolina Montaño, Stanislaw A Gorski, André Nussenzweig, Tom Misteli, Robert D Phair, Rafael Casellas. Nature 2007
Michael Kruhlak, Elizabeth E Crouch, Marika Orlov, Carolina Montaño, Stanislaw A Gorski, André Nussenzweig, Tom Misteli, Robert D Phair, Rafael Casellas. Nature 2007
42
The Treacher Collins syndrome (TCOF1) gene product is involved in ribosomal DNA gene transcription by interacting with upstream binding factor.
Benigno C Valdez, Dale Henning, Rolando B So, Jill Dixon, Michael J Dixon. Proc Natl Acad Sci U S A 2004
Benigno C Valdez, Dale Henning, Rolando B So, Jill Dixon, Michael J Dixon. Proc Natl Acad Sci U S A 2004
33
ATM Dependent Silencing Links Nucleolar Chromatin Reorganization to DNA Damage Recognition.
Shane M Harding, Jonathan A Boiarsky, Roger A Greenberg. Cell Rep 2015
Shane M Harding, Jonathan A Boiarsky, Roger A Greenberg. Cell Rep 2015
33
A localized nucleolar DNA damage response facilitates recruitment of the homology-directed repair machinery independent of cell cycle stage.
Marjolein van Sluis, Brian McStay. Genes Dev 2015
Marjolein van Sluis, Brian McStay. Genes Dev 2015
31
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
Shuhei Matsuoka, Bryan A Ballif, Agata Smogorzewska, E Robert McDonald, Kristen E Hurov, Ji Luo, Corey E Bakalarski, Zhenming Zhao, Nicole Solimini, Yaniv Lerenthal,[...]. Science 2007
Shuhei Matsuoka, Bryan A Ballif, Agata Smogorzewska, E Robert McDonald, Kristen E Hurov, Ji Luo, Corey E Bakalarski, Zhenming Zhao, Nicole Solimini, Yaniv Lerenthal,[...]. Science 2007
26
Tcof1/Treacle is required for neural crest cell formation and proliferation deficiencies that cause craniofacial abnormalities.
Jill Dixon, Natalie C Jones, Lisa L Sandell, Sachintha M Jayasinghe, Jennifer Crane, Jean-Philippe Rey, Michael J Dixon, Paul A Trainor. Proc Natl Acad Sci U S A 2006
Jill Dixon, Natalie C Jones, Lisa L Sandell, Sachintha M Jayasinghe, Jennifer Crane, Jean-Philippe Rey, Michael J Dixon, Paul A Trainor. Proc Natl Acad Sci U S A 2006
23
Prevention of the neurocristopathy Treacher Collins syndrome through inhibition of p53 function.
Natalie C Jones, Megan L Lynn, Karin Gaudenz, Daisuke Sakai, Kazushi Aoto, Jean-Phillipe Rey, Earl F Glynn, Lacey Ellington, Chunying Du, Jill Dixon,[...]. Nat Med 2008
Natalie C Jones, Megan L Lynn, Karin Gaudenz, Daisuke Sakai, Kazushi Aoto, Jean-Phillipe Rey, Earl F Glynn, Lacey Ellington, Chunying Du, Jill Dixon,[...]. Nat Med 2008
23
Breaks in the 45S rDNA Lead to Recombination-Mediated Loss of Repeats.
Daniël O Warmerdam, Jeroen van den Berg, René H Medema. Cell Rep 2016
Daniël O Warmerdam, Jeroen van den Berg, René H Medema. Cell Rep 2016
29
Mutations in genes encoding subunits of RNA polymerases I and III cause Treacher Collins syndrome.
Johannes G Dauwerse, Jill Dixon, Saskia Seland, Claudia A L Ruivenkamp, Arie van Haeringen, Lies H Hoefsloot, Dorien J M Peters, Agnes Clement-de Boers, Cornelia Daumer-Haas, Robert Maiwald,[...]. Nat Genet 2011
Johannes G Dauwerse, Jill Dixon, Saskia Seland, Claudia A L Ruivenkamp, Arie van Haeringen, Lies H Hoefsloot, Dorien J M Peters, Agnes Clement-de Boers, Cornelia Daumer-Haas, Robert Maiwald,[...]. Nat Genet 2011
20
Loss of Bloom syndrome protein destabilizes human gene cluster architecture.
Michael W Killen, Dawn M Stults, Noritaka Adachi, Les Hanakahi, Andrew J Pierce. Hum Mol Genet 2009
Michael W Killen, Dawn M Stults, Noritaka Adachi, Les Hanakahi, Andrew J Pierce. Hum Mol Genet 2009
22
Human rRNA gene clusters are recombinational hotspots in cancer.
Dawn M Stults, Michael W Killen, Erica P Williamson, Jon S Hourigan, H David Vargas, Susanne M Arnold, Jeffrey A Moscow, Andrew J Pierce. Cancer Res 2009
Dawn M Stults, Michael W Killen, Erica P Williamson, Jon S Hourigan, H David Vargas, Susanne M Arnold, Jeffrey A Moscow, Andrew J Pierce. Cancer Res 2009
18
Prevention of Treacher Collins syndrome craniofacial anomalies in mouse models via maternal antioxidant supplementation.
Daisuke Sakai, Jill Dixon, Annita Achilleos, Michael Dixon, Paul A Trainor. Nat Commun 2016
Daisuke Sakai, Jill Dixon, Annita Achilleos, Michael Dixon, Paul A Trainor. Nat Commun 2016
25
Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair.
Elijahu Berkovich, Raymond J Monnat, Michael B Kastan. Nat Cell Biol 2007
Elijahu Berkovich, Raymond J Monnat, Michael B Kastan. Nat Cell Biol 2007
17
The nucleolus under stress.
Séverine Boulon, Belinda J Westman, Saskia Hutten, François-Michel Boisvert, Angus I Lamond. Mol Cell 2010
Séverine Boulon, Belinda J Westman, Saskia Hutten, François-Michel Boisvert, Angus I Lamond. Mol Cell 2010
17
ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks.
Niraj M Shanbhag, Ilona U Rafalska-Metcalf, Carlo Balane-Bolivar, Susan M Janicki, Roger A Greenberg. Cell 2010
Niraj M Shanbhag, Ilona U Rafalska-Metcalf, Carlo Balane-Bolivar, Susan M Janicki, Roger A Greenberg. Cell 2010
17
The Treacher Collins syndrome (TCOF1) gene product is involved in pre-rRNA methylation.
Bianca Gonzales, Dale Henning, Rolando B So, Jill Dixon, Michael J Dixon, Benigno C Valdez. Hum Mol Genet 2005
Bianca Gonzales, Dale Henning, Rolando B So, Jill Dixon, Michael J Dixon, Benigno C Valdez. Hum Mol Genet 2005
17
Positional cloning of a gene involved in the pathogenesis of Treacher Collins syndrome. The Treacher Collins Syndrome Collaborative Group.
. Nat Genet 1996
. Nat Genet 1996
17
Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses.
Carlos P Rubbi, Jo Milner. EMBO J 2003
Carlos P Rubbi, Jo Milner. EMBO J 2003
15
Cell-fate determination by ubiquitin-dependent regulation of translation.
Achim Werner, Shintaro Iwasaki, Colleen A McGourty, Sofia Medina-Ruiz, Nia Teerikorpi, Indro Fedrigo, Nicholas T Ingolia, Michael Rape. Nature 2015
Achim Werner, Shintaro Iwasaki, Colleen A McGourty, Sofia Medina-Ruiz, Nia Teerikorpi, Indro Fedrigo, Nicholas T Ingolia, Michael Rape. Nature 2015
15
Quantitative proteomics and dynamic imaging of the nucleolus reveal distinct responses to UV and ionizing radiation.
Henna M Moore, Baoyan Bai, François-Michel Boisvert, Leena Latonen, Ville Rantanen, Jeremy C Simpson, Rainer Pepperkok, Angus I Lamond, Marikki Laiho. Mol Cell Proteomics 2011
Henna M Moore, Baoyan Bai, François-Michel Boisvert, Leena Latonen, Ville Rantanen, Jeremy C Simpson, Rainer Pepperkok, Angus I Lamond, Marikki Laiho. Mol Cell Proteomics 2011
14
The shared genomic architecture of human nucleolar organizer regions.
Ioanna Floutsakou, Saumya Agrawal, Thong T Nguyen, Cathal Seoighe, Austen R D Ganley, Brian McStay. Genome Res 2013
Ioanna Floutsakou, Saumya Agrawal, Thong T Nguyen, Cathal Seoighe, Austen R D Ganley, Brian McStay. Genome Res 2013
14
The DNA-damage response in human biology and disease.
Stephen P Jackson, Jiri Bartek. Nature 2009
Stephen P Jackson, Jiri Bartek. Nature 2009
14
Ribosomopathies: human disorders of ribosome dysfunction.
Anupama Narla, Benjamin L Ebert. Blood 2010
Anupama Narla, Benjamin L Ebert. Blood 2010
14
Targeting RNA polymerase I with an oral small molecule CX-5461 inhibits ribosomal RNA synthesis and solid tumor growth.
Denis Drygin, Amy Lin, Josh Bliesath, Caroline B Ho, Sean E O'Brien, Chris Proffitt, Mayuko Omori, Mustapha Haddach, Michael K Schwaebe, Adam Siddiqui-Jain,[...]. Cancer Res 2011
Denis Drygin, Amy Lin, Josh Bliesath, Caroline B Ho, Sean E O'Brien, Chris Proffitt, Mayuko Omori, Mustapha Haddach, Michael K Schwaebe, Adam Siddiqui-Jain,[...]. Cancer Res 2011
14
TCOF1 gene encodes a putative nucleolar phosphoprotein that exhibits mutations in Treacher Collins Syndrome throughout its coding region.
C A Wise, L C Chiang, W A Paznekas, M Sharma, M M Musy, J A Ashley, M Lovett, E W Jabs. Proc Natl Acad Sci U S A 1997
C A Wise, L C Chiang, W A Paznekas, M Sharma, M M Musy, J A Ashley, M Lovett, E W Jabs. Proc Natl Acad Sci U S A 1997
14
Nucleolar responses to DNA double-strand breaks.
Dorthe Helena Larsen, Manuel Stucki. Nucleic Acids Res 2016
Dorthe Helena Larsen, Manuel Stucki. Nucleic Acids Res 2016
20
Treacle recruits RNA polymerase I complex to the nucleolus that is independent of UBF.
Chen-I Lin, Ning-Hsing Yeh. Biochem Biophys Res Commun 2009
Chen-I Lin, Ning-Hsing Yeh. Biochem Biophys Res Commun 2009
37
Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders.
Eliezer Calo, Bo Gu, Margot E Bowen, Fardin Aryan, Antoine Zalc, Jialiang Liang, Ryan A Flynn, Tomek Swigut, Howard Y Chang, Laura D Attardi,[...]. Nature 2018
Eliezer Calo, Bo Gu, Margot E Bowen, Fardin Aryan, Antoine Zalc, Jialiang Liang, Ryan A Flynn, Tomek Swigut, Howard Y Chang, Laura D Attardi,[...]. Nature 2018
15
The Smc5-Smc6 complex and SUMO modification of Rad52 regulates recombinational repair at the ribosomal gene locus.
Jordi Torres-Rosell, Ivana Sunjevaric, Giacomo De Piccoli, Meik Sacher, Nadine Eckert-Boulet, Robert Reid, Stefan Jentsch, Rodney Rothstein, Luis Aragón, Michael Lisby. Nat Cell Biol 2007
Jordi Torres-Rosell, Ivana Sunjevaric, Giacomo De Piccoli, Meik Sacher, Nadine Eckert-Boulet, Robert Reid, Stefan Jentsch, Rodney Rothstein, Luis Aragón, Michael Lisby. Nat Cell Biol 2007
13
Genomic architecture and inheritance of human ribosomal RNA gene clusters.
Dawn M Stults, Michael W Killen, Heather H Pierce, Andrew J Pierce. Genome Res 2008
Dawn M Stults, Michael W Killen, Heather H Pierce, Andrew J Pierce. Genome Res 2008
13
Proteomic analysis of human Nop56p-associated pre-ribosomal ribonucleoprotein complexes. Possible link between Nop56p and the nucleolar protein treacle responsible for Treacher Collins syndrome.
Toshiya Hayano, Mitsuaki Yanagida, Yoshio Yamauchi, Takashi Shinkawa, Toshiaki Isobe, Nobuhiro Takahashi. J Biol Chem 2003
Toshiya Hayano, Mitsuaki Yanagida, Yoshio Yamauchi, Takashi Shinkawa, Toshiaki Isobe, Nobuhiro Takahashi. J Biol Chem 2003
13
Treacher Collins syndrome: etiology, pathogenesis and prevention.
Paul A Trainor, Jill Dixon, Michael J Dixon. Eur J Hum Genet 2009
Paul A Trainor, Jill Dixon, Michael J Dixon. Eur J Hum Genet 2009
13
The epigenetics of rRNA genes: from molecular to chromosome biology.
Brian McStay, Ingrid Grummt. Annu Rev Cell Dev Biol 2008
Brian McStay, Ingrid Grummt. Annu Rev Cell Dev Biol 2008
13
The multifunctional nucleolus.
François-Michel Boisvert, Silvana van Koningsbruggen, Joaquín Navascués, Angus I Lamond. Nat Rev Mol Cell Biol 2007
François-Michel Boisvert, Silvana van Koningsbruggen, Joaquín Navascués, Angus I Lamond. Nat Rev Mol Cell Biol 2007
13
Characterization of the nucleolar gene product, treacle, in Treacher Collins syndrome.
C Isaac, K L Marsh, W A Paznekas, J Dixon, M J Dixon, E W Jabs, U T Meier. Mol Biol Cell 2000
C Isaac, K L Marsh, W A Paznekas, J Dixon, M J Dixon, E W Jabs, U T Meier. Mol Biol Cell 2000
13
Nucleolar organizer regions: genomic 'dark matter' requiring illumination.
Brian McStay. Genes Dev 2016
Brian McStay. Genes Dev 2016
13
Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation.
Clémence Mooser, Ioanna-Eleni Symeonidou, Pia-Amata Leimbacher, Alison Ribeiro, Ann-Marie K Shorrocks, Stephanie Jungmichel, Sara C Larsen, Katja Knechtle, Arti Jasrotia, Diana Zurbriggen,[...]. Nat Commun 2020
Clémence Mooser, Ioanna-Eleni Symeonidou, Pia-Amata Leimbacher, Alison Ribeiro, Ann-Marie K Shorrocks, Stephanie Jungmichel, Sara C Larsen, Katja Knechtle, Arti Jasrotia, Diana Zurbriggen,[...]. Nat Commun 2020
45
Transcriptional elongation factor ENL phosphorylated by ATM recruits polycomb and switches off transcription for DSB repair.
Ayako Ui, Yuko Nagaura, Akira Yasui. Mol Cell 2015
Ayako Ui, Yuko Nagaura, Akira Yasui. Mol Cell 2015
11
Requirement for PBAF in transcriptional repression and repair at DNA breaks in actively transcribed regions of chromatin.
Andreas Kakarougkas, Amani Ismail, Anna L Chambers, Enriqueta Riballo, Alex D Herbert, Julia Künzel, Markus Löbrich, Penny A Jeggo, Jessica A Downs. Mol Cell 2014
Andreas Kakarougkas, Amani Ismail, Anna L Chambers, Enriqueta Riballo, Alex D Herbert, Julia Künzel, Markus Löbrich, Penny A Jeggo, Jessica A Downs. Mol Cell 2014
11
Dynamic sorting of nuclear components into distinct nucleolar caps during transcriptional inhibition.
Yaron Shav-Tal, Janna Blechman, Xavier Darzacq, Cristina Montagna, Billy T Dye, James G Patton, Robert H Singer, Dov Zipori. Mol Biol Cell 2005
Yaron Shav-Tal, Janna Blechman, Xavier Darzacq, Cristina Montagna, Billy T Dye, James G Patton, Robert H Singer, Dov Zipori. Mol Biol Cell 2005
11
Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53.
Megan J Bywater, Gretchen Poortinga, Elaine Sanij, Nadine Hein, Abigail Peck, Carleen Cullinane, Meaghan Wall, Leonie Cluse, Denis Drygin, Kenna Anderes,[...]. Cancer Cell 2012
Megan J Bywater, Gretchen Poortinga, Elaine Sanij, Nadine Hein, Abigail Peck, Carleen Cullinane, Meaghan Wall, Leonie Cluse, Denis Drygin, Kenna Anderes,[...]. Cancer Cell 2012
11
Abundance of ribosomal RNA gene copies maintains genome integrity.
Satoru Ide, Takaaki Miyazaki, Hisaji Maki, Takehiko Kobayashi. Science 2010
Satoru Ide, Takaaki Miyazaki, Hisaji Maki, Takehiko Kobayashi. Science 2010
11
Genetic background has a major effect on the penetrance and severity of craniofacial defects in mice heterozygous for the gene encoding the nucleolar protein Treacle.
Jill Dixon, Michael James Dixon. Dev Dyn 2004
Jill Dixon, Michael James Dixon. Dev Dyn 2004
11
Nucleolar reorganization in response to rDNA damage.
Marjolein van Sluis, Brian McStay. Curr Opin Cell Biol 2017
Marjolein van Sluis, Brian McStay. Curr Opin Cell Biol 2017
17
Double-strand breaks in ribosomal RNA genes activate a distinct signaling and chromatin response to facilitate nucleolar restructuring and repair.
Lea M Korsholm, Zita Gál, Lin Lin, Oliver Quevedo, Diana A Ahmad, Ekaterina Dulina, Yonglun Luo, Jiri Bartek, Dorthe H Larsen. Nucleic Acids Res 2019
Lea M Korsholm, Zita Gál, Lin Lin, Oliver Quevedo, Diana A Ahmad, Ekaterina Dulina, Yonglun Luo, Jiri Bartek, Dorthe H Larsen. Nucleic Acids Res 2019
28
Recruitment of factors linking transcription and processing of pre-rRNA to NOR chromatin is UBF-dependent and occurs independent of transcription in human cells.
José-Luis Prieto, Brian McStay. Genes Dev 2007
José-Luis Prieto, Brian McStay. Genes Dev 2007
10
Construction of synthetic nucleoli in human cells reveals how a major functional nuclear domain is formed and propagated through cell division.
Alice Grob, Christine Colleran, Brian McStay. Genes Dev 2014
Alice Grob, Christine Colleran, Brian McStay. Genes Dev 2014
10
DNAPKcs-dependent arrest of RNA polymerase II transcription in the presence of DNA breaks.
Tibor Pankotai, Céline Bonhomme, David Chen, Evi Soutoglou. Nat Struct Mol Biol 2012
Tibor Pankotai, Céline Bonhomme, David Chen, Evi Soutoglou. Nat Struct Mol Biol 2012
10
The DNA damage response: making it safe to play with knives.
Alberto Ciccia, Stephen J Elledge. Mol Cell 2010
Alberto Ciccia, Stephen J Elledge. Mol Cell 2010
10
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.