A citation-based method for searching scientific literature

Meritxell Huch, Helmuth Gehart, Ruben van Boxtel, Karien Hamer, Francis Blokzijl, Monique M A Verstegen, Ewa Ellis, Martien van Wenum, Sabine A Fuchs, Joep de Ligt, Marc van de Wetering, Nobuo Sasaki, Susanne J Boers, Hans Kemperman, Jeroen de Jonge, Jan N M Ijzermans, Edward E S Nieuwenhuis, Ruurdtje Hoekstra, Stephen Strom, Robert R G Vries, Luc J W van der Laan, Edwin Cuppen, Hans Clevers. Cell 2015
Times Cited: 726







List of co-cited articles
1169 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche.
Toshiro Sato, Robert G Vries, Hugo J Snippert, Marc van de Wetering, Nick Barker, Daniel E Stange, Johan H van Es, Arie Abo, Pekka Kujala, Peter J Peters,[...]. Nature 2009
40

In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration.
Meritxell Huch, Craig Dorrell, Sylvia F Boj, Johan H van Es, Vivian S W Li, Marc van de Wetering, Toshiro Sato, Karien Hamer, Nobuo Sasaki, Milton J Finegold,[...]. Nature 2013
839
32

Human primary liver cancer-derived organoid cultures for disease modeling and drug screening.
Laura Broutier, Gianmarco Mastrogiovanni, Monique Ma Verstegen, Hayley E Francies, Lena Morrill Gavarró, Charles R Bradshaw, George E Allen, Robert Arnes-Benito, Olga Sidorova, Marcia P Gaspersz,[...]. Nat Med 2017
465
29


Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium.
Toshiro Sato, Daniel E Stange, Marc Ferrante, Robert G J Vries, Johan H Van Es, Stieneke Van den Brink, Winan J Van Houdt, Apollo Pronk, Joost Van Gorp, Peter D Siersema,[...]. Gastroenterology 2011
26

Prospective derivation of a living organoid biobank of colorectal cancer patients.
Marc van de Wetering, Hayley E Francies, Joshua M Francis, Gergana Bounova, Francesco Iorio, Apollo Pronk, Winan van Houdt, Joost van Gorp, Amaro Taylor-Weiner, Lennart Kester,[...]. Cell 2015
25

Vascularized and functional human liver from an iPSC-derived organ bud transplant.
Takanori Takebe, Keisuke Sekine, Masahiro Enomura, Hiroyuki Koike, Masaki Kimura, Takunori Ogaeri, Ran-Ran Zhang, Yasuharu Ueno, Yun-Wen Zheng, Naoto Koike,[...]. Nature 2013
24

Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids.
Huili Hu, Helmuth Gehart, Benedetta Artegiani, Carmen LÖpez-Iglesias, Florijn Dekkers, Onur Basak, Johan van Es, Susana M Chuva de Sousa Lopes, Harry Begthel, Jeroen Korving,[...]. Cell 2018
235
23

Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation.
Laura Broutier, Amanda Andersson-Rolf, Christopher J Hindley, Sylvia F Boj, Hans Clevers, Bon-Kyoung Koo, Meritxell Huch. Nat Protoc 2016
280
22

Cerebral organoids model human brain development and microcephaly.
Madeline A Lancaster, Magdalena Renner, Carol-Anne Martin, Daniel Wenzel, Louise S Bicknell, Matthew E Hurles, Tessa Homfray, Josef M Penninger, Andrew P Jackson, Juergen A Knoblich. Nature 2013
21

Organoid models of human and mouse ductal pancreatic cancer.
Sylvia F Boj, Chang-Il Hwang, Lindsey A Baker, Iok In Christine Chio, Dannielle D Engle, Vincenzo Corbo, Myrthe Jager, Mariano Ponz-Sarvise, Hervé Tiriac, Mona S Spector,[...]. Cell 2015
981
20

Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids.
Fotios Sampaziotis, Alexander W Justin, Olivia C Tysoe, Stephen Sawiak, Edmund M Godfrey, Sara S Upponi, Richard L Gieseck, Miguel Cardoso de Brito, Natalie Lie Berntsen, María J Gómez-Vázquez,[...]. Nat Med 2017
129
19

Long-term expanding human airway organoids for disease modeling.
Norman Sachs, Angelos Papaspyropoulos, Domenique D Zomer-van Ommen, Inha Heo, Lena Böttinger, Dymph Klay, Fleur Weeber, Guizela Huelsz-Prince, Nino Iakobachvili, Gimano D Amatngalim,[...]. EMBO J 2019
291
19

In vitro expansion of human gastric epithelial stem cells and their responses to bacterial infection.
Sina Bartfeld, Tülay Bayram, Marc van de Wetering, Meritxell Huch, Harry Begthel, Pekka Kujala, Robert Vries, Peter J Peters, Hans Clevers. Gastroenterology 2015
378
18

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers.
Georgios Vlachogiannis, Somaieh Hedayat, Alexandra Vatsiou, Yann Jamin, Javier Fernández-Mateos, Khurum Khan, Andrea Lampis, Katherine Eason, Ian Huntingford, Rosemary Burke,[...]. Science 2018
643
17

A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity.
Norman Sachs, Joep de Ligt, Oded Kopper, Ewa Gogola, Gergana Bounova, Fleur Weeber, Anjali Vanita Balgobind, Karin Wind, Ana Gracanin, Harry Begthel,[...]. Cell 2018
606
17

Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro.
Jason R Spence, Christopher N Mayhew, Scott A Rankin, Matthew F Kuhar, Jefferson E Vallance, Kathryn Tolle, Elizabeth E Hoskins, Vladimir V Kalinichenko, Susanne I Wells, Aaron M Zorn,[...]. Nature 2011
16


Designer matrices for intestinal stem cell and organoid culture.
Nikolce Gjorevski, Norman Sachs, Andrea Manfrin, Sonja Giger, Maiia E Bragina, Paloma Ordóñez-Morán, Hans Clevers, Matthias P Lutolf. Nature 2016
599
16

A Colorectal Tumor Organoid Library Demonstrates Progressive Loss of Niche Factor Requirements during Tumorigenesis.
Masayuki Fujii, Mariko Shimokawa, Shoichi Date, Ai Takano, Mami Matano, Kosaku Nanki, Yuki Ohta, Kohta Toshimitsu, Yoshihiro Nakazato, Kenta Kawasaki,[...]. Cell Stem Cell 2016
367
15

Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids.
Rie Ouchi, Shodai Togo, Masaki Kimura, Tadahiro Shinozawa, Masaru Koido, Hiroyuki Koike, Wendy Thompson, Rebekah A Karns, Christopher N Mayhew, Patrick S McGrath,[...]. Cell Metab 2019
134
15

Modelling human development and disease in pluripotent stem-cell-derived gastric organoids.
Kyle W McCracken, Emily M Catá, Calyn M Crawford, Katie L Sinagoga, Michael Schumacher, Briana E Rockich, Yu-Hwai Tsai, Christopher N Mayhew, Jason R Spence, Yana Zavros,[...]. Nature 2014
516
14

Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture.
Weng Chuan Peng, Catriona Y Logan, Matt Fish, Teni Anbarchian, Francis Aguisanda, Adrián Álvarez-Varela, Peng Wu, Yinhua Jin, Junjie Zhu, Bin Li,[...]. Cell 2018
104
14

Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis.
Meritxell Huch, Paola Bonfanti, Sylvia F Boj, Toshiro Sato, Cindy J M Loomans, Marc van de Wetering, Mozhdeh Sojoodi, Vivian S W Li, Jurian Schuijers, Ana Gracanin,[...]. EMBO J 2013
401
13

Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids.
Krijn K Dijkstra, Chiara M Cattaneo, Fleur Weeber, Myriam Chalabi, Joris van de Haar, Lorenzo F Fanchi, Maarten Slagter, Daphne L van der Velden, Sovann Kaing, Sander Kelderman,[...]. Cell 2018
332
13

Organoid Models of Human Liver Cancers Derived from Tumor Needle Biopsies.
Sandro Nuciforo, Isabel Fofana, Matthias S Matter, Tanja Blumer, Diego Calabrese, Tujana Boldanova, Salvatore Piscuoglio, Stefan Wieland, Femke Ringnalda, Gerald Schwank,[...]. Cell Rep 2018
146
13

Organoid cultures derived from patients with advanced prostate cancer.
Dong Gao, Ian Vela, Andrea Sboner, Phillip J Iaquinta, Wouter R Karthaus, Anuradha Gopalan, Catherine Dowling, Jackline N Wanjala, Eva A Undvall, Vivek K Arora,[...]. Cell 2014
763
13

Sequential cancer mutations in cultured human intestinal stem cells.
Jarno Drost, Richard H van Jaarsveld, Bas Ponsioen, Cheryl Zimberlin, Ruben van Boxtel, Arjan Buijs, Norman Sachs, René M Overmeer, G Johan Offerhaus, Harry Begthel,[...]. Nature 2015
550
13

Organoids as an in vitro model of human development and disease.
Aliya Fatehullah, Si Hui Tan, Nick Barker. Nat Cell Biol 2016
668
13

Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids.
Benedetta Artegiani, Lisa van Voorthuijsen, Rik G H Lindeboom, Daniëlle Seinstra, Inha Heo, Pablo Tapia, Carmen López-Iglesias, Daniel Postrach, Talya Dayton, Rurika Oka,[...]. Cell Stem Cell 2019
69
17

Generation of expandable human pluripotent stem cell-derived hepatocyte-like liver organoids.
Seon Ju Mun, Jae-Sung Ryu, Mi-Ok Lee, Ye Seul Son, Soo Jin Oh, Hyun-Soo Cho, Mi-Young Son, Dae-Soo Kim, Su Jung Kim, Hyun Ju Yoo,[...]. J Hepatol 2019
69
17

In vitro generation of human pluripotent stem cell derived lung organoids.
Briana R Dye, David R Hill, Michael A H Ferguson, Yu-Hwai Tsai, Melinda S Nagy, Rachel Dyal, James M Wells, Christopher N Mayhew, Roy Nattiv, Ophir D Klein,[...]. Elife 2015
392
11

Induction of pluripotent stem cells from adult human fibroblasts by defined factors.
Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki, Megumi Narita, Tomoko Ichisaka, Kiichiro Tomoda, Shinya Yamanaka. Cell 2007
11

Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis.
Johanna F Dekkers, Gitte Berkers, Evelien Kruisselbrink, Annelotte Vonk, Hugo R de Jonge, Hettie M Janssens, Inez Bronsveld, Eduard A van de Graaf, Edward E S Nieuwenhuis, Roderick H J Houwen,[...]. Sci Transl Med 2016
281
11

Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure.
Xuyu Qian, Ha Nam Nguyen, Mingxi M Song, Christopher Hadiono, Sarah C Ogden, Christy Hammack, Bing Yao, Gregory R Hamersky, Fadi Jacob, Chun Zhong,[...]. Cell 2016
11

An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity.
Oded Kopper, Chris J de Witte, Kadi Lõhmussaar, Jose Espejo Valle-Inclan, Nizar Hami, Lennart Kester, Anjali Vanita Balgobind, Jeroen Korving, Natalie Proost, Harry Begthel,[...]. Nat Med 2019
238
11

Organoid Modeling of the Tumor Immune Microenvironment.
James T Neal, Xingnan Li, Junjie Zhu, Valeria Giangarra, Caitlin L Grzeskowiak, Jihang Ju, Iris H Liu, Shin-Heng Chiou, Ameen A Salahudeen, Amber R Smith,[...]. Cell 2018
428
11

Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer.
Hervé Tiriac, Pascal Belleau, Dannielle D Engle, Dennis Plenker, Astrid Deschênes, Tim D D Somerville, Fieke E M Froeling, Richard A Burkhart, Robert E Denroche, Gun-Ho Jang,[...]. Cancer Discov 2018
354
11

A functional CFTR assay using primary cystic fibrosis intestinal organoids.
Johanna F Dekkers, Caroline L Wiegerinck, Hugo R de Jonge, Inez Bronsveld, Hettie M Janssens, Karin M de Winter-de Groot, Arianne M Brandsma, Nienke W M de Jong, Marcel J C Bijvelds, Bob J Scholte,[...]. Nat Med 2013
549
11

Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis.
Minoru Takasato, Pei X Er, Han S Chiu, Barbara Maier, Gregory J Baillie, Charles Ferguson, Robert G Parton, Ernst J Wolvetang, Matthias S Roost, Susana M Chuva de Sousa Lopes,[...]. Nature 2015
692
11

Human ESC-derived expandable hepatic organoids enable therapeutic liver repopulation and pathophysiological modeling of alcoholic liver injury.
Shuyong Wang, Xuan Wang, Zuolong Tan, Yuxin Su, Juan Liu, Mingyang Chang, Fang Yan, Jie Chen, Tao Chen, Chuanjiang Li,[...]. Cell Res 2019
48
22

Massive and Reproducible Production of Liver Buds Entirely from Human Pluripotent Stem Cells.
Takanori Takebe, Keisuke Sekine, Masaki Kimura, Emi Yoshizawa, Satoru Ayano, Masaru Koido, Shizuka Funayama, Noriko Nakanishi, Tomoko Hisai, Tatsuya Kobayashi,[...]. Cell Rep 2017
151
11

Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation.
Fotios Sampaziotis, Miguel Cardoso de Brito, Pedro Madrigal, Alessandro Bertero, Kourosh Saeb-Parsy, Filipa A C Soares, Elisabeth Schrumpf, Espen Melum, Tom H Karlsen, J Andrew Bradley,[...]. Nat Biotechnol 2015
212
11

Human hepatic organoids for the analysis of human genetic diseases.
Yuan Guan, Dan Xu, Phillip M Garfin, Ursula Ehmer, Melissa Hurwitz, Greg Enns, Sara Michie, Manhong Wu, Ming Zheng, Toshihiko Nishimura,[...]. JCI Insight 2017
79
13

Modelling Cryptosporidium infection in human small intestinal and lung organoids.
Inha Heo, Devanjali Dutta, Deborah A Schaefer, Nino Iakobachvili, Benedetta Artegiani, Norman Sachs, Kim E Boonekamp, Gregory Bowden, Antoni P A Hendrickx, Robert J L Willems,[...]. Nat Microbiol 2018
163
10

Identification of multipotent luminal progenitor cells in human prostate organoid cultures.
Wouter R Karthaus, Phillip J Iaquinta, Jarno Drost, Ana Gracanin, Ruben van Boxtel, John Wongvipat, Catherine M Dowling, Dong Gao, Harry Begthel, Norman Sachs,[...]. Cell 2014
388
10

Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro.
Nick Barker, Meritxell Huch, Pekka Kujala, Marc van de Wetering, Hugo J Snippert, Johan H van Es, Toshiro Sato, Daniel E Stange, Harry Begthel, Maaike van den Born,[...]. Cell Stem Cell 2010
981
10

Organoids in cancer research.
Jarno Drost, Hans Clevers. Nat Rev Cancer 2018
539
10

Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression.
Takashi Seino, Shintaro Kawasaki, Mariko Shimokawa, Hiroki Tamagawa, Kohta Toshimitsu, Masayuki Fujii, Yuki Ohta, Mami Matano, Kosaku Nanki, Kenta Kawasaki,[...]. Cell Stem Cell 2018
260
10

Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell- and patient-derived tumor organoids.
Ling Huang, Audrey Holtzinger, Ishaan Jagan, Michael BeGora, Ines Lohse, Nicholas Ngai, Cristina Nostro, Rennian Wang, Lakshmi B Muthuswamy, Howard C Crawford,[...]. Nat Med 2015
359
10


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.