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Times Cited: 726
Times Cited
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Similarity
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche.
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In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration.
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Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids.
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Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation.
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Cerebral organoids model human brain development and microcephaly.
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Organoid models of human and mouse ductal pancreatic cancer.
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Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids.
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Long-term expanding human airway organoids for disease modeling.
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In vitro expansion of human gastric epithelial stem cells and their responses to bacterial infection.
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Patient-derived organoids model treatment response of metastatic gastrointestinal cancers.
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A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity.
Norman Sachs, Joep de Ligt, Oded Kopper, Ewa Gogola, Gergana Bounova, Fleur Weeber, Anjali Vanita Balgobind, Karin Wind, Ana Gracanin, Harry Begthel,[...]. Cell 2018
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Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro.
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Organogenesis in a dish: modeling development and disease using organoid technologies.
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Designer matrices for intestinal stem cell and organoid culture.
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A Colorectal Tumor Organoid Library Demonstrates Progressive Loss of Niche Factor Requirements during Tumorigenesis.
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Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids.
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Modelling human development and disease in pluripotent stem-cell-derived gastric organoids.
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Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture.
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Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis.
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Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids.
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Organoid Models of Human Liver Cancers Derived from Tumor Needle Biopsies.
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Organoid cultures derived from patients with advanced prostate cancer.
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Sequential cancer mutations in cultured human intestinal stem cells.
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Organoids as an in vitro model of human development and disease.
Aliya Fatehullah, Si Hui Tan, Nick Barker. Nat Cell Biol 2016
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Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids.
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Benedetta Artegiani, Lisa van Voorthuijsen, Rik G H Lindeboom, Daniëlle Seinstra, Inha Heo, Pablo Tapia, Carmen López-Iglesias, Daniel Postrach, Talya Dayton, Rurika Oka,[...]. Cell Stem Cell 2019
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Generation of expandable human pluripotent stem cell-derived hepatocyte-like liver organoids.
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In vitro generation of human pluripotent stem cell derived lung organoids.
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Briana R Dye, David R Hill, Michael A H Ferguson, Yu-Hwai Tsai, Melinda S Nagy, Rachel Dyal, James M Wells, Christopher N Mayhew, Roy Nattiv, Ophir D Klein,[...]. Elife 2015
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Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis.
Johanna F Dekkers, Gitte Berkers, Evelien Kruisselbrink, Annelotte Vonk, Hugo R de Jonge, Hettie M Janssens, Inez Bronsveld, Eduard A van de Graaf, Edward E S Nieuwenhuis, Roderick H J Houwen,[...]. Sci Transl Med 2016
Johanna F Dekkers, Gitte Berkers, Evelien Kruisselbrink, Annelotte Vonk, Hugo R de Jonge, Hettie M Janssens, Inez Bronsveld, Eduard A van de Graaf, Edward E S Nieuwenhuis, Roderick H J Houwen,[...]. Sci Transl Med 2016
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Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure.
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An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity.
Oded Kopper, Chris J de Witte, Kadi Lõhmussaar, Jose Espejo Valle-Inclan, Nizar Hami, Lennart Kester, Anjali Vanita Balgobind, Jeroen Korving, Natalie Proost, Harry Begthel,[...]. Nat Med 2019
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Organoid Modeling of the Tumor Immune Microenvironment.
James T Neal, Xingnan Li, Junjie Zhu, Valeria Giangarra, Caitlin L Grzeskowiak, Jihang Ju, Iris H Liu, Shin-Heng Chiou, Ameen A Salahudeen, Amber R Smith,[...]. Cell 2018
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Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer.
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A functional CFTR assay using primary cystic fibrosis intestinal organoids.
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Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis.
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Human ESC-derived expandable hepatic organoids enable therapeutic liver repopulation and pathophysiological modeling of alcoholic liver injury.
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Massive and Reproducible Production of Liver Buds Entirely from Human Pluripotent Stem Cells.
Takanori Takebe, Keisuke Sekine, Masaki Kimura, Emi Yoshizawa, Satoru Ayano, Masaru Koido, Shizuka Funayama, Noriko Nakanishi, Tomoko Hisai, Tatsuya Kobayashi,[...]. Cell Rep 2017
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Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation.
Fotios Sampaziotis, Miguel Cardoso de Brito, Pedro Madrigal, Alessandro Bertero, Kourosh Saeb-Parsy, Filipa A C Soares, Elisabeth Schrumpf, Espen Melum, Tom H Karlsen, J Andrew Bradley,[...]. Nat Biotechnol 2015
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Human hepatic organoids for the analysis of human genetic diseases.
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Modelling Cryptosporidium infection in human small intestinal and lung organoids.
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Identification of multipotent luminal progenitor cells in human prostate organoid cultures.
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Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro.
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Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression.
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Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell- and patient-derived tumor organoids.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.