A citation-based method for searching scientific literature

Kanae Yumimoto, Sayuri Akiyoshi, Hiroki Ueo, Yasuaki Sagara, Ichiro Onoyama, Hiroaki Ueo, Shinji Ohno, Masaki Mori, Koshi Mimori, Keiichi I Nakayama. J Clin Invest 2015
Times Cited: 77







List of co-cited articles
776 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity



Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7.
Masayoshi Yada, Shigetsugu Hatakeyama, Takumi Kamura, Masaaki Nishiyama, Ryosuke Tsunematsu, Hiroyuki Imaki, Noriko Ishida, Fumihiko Okumura, Keiko Nakayama, Keiichi I Nakayama. EMBO J 2004
575
18

Tumor suppression by the Fbw7 ubiquitin ligase: mechanisms and opportunities.
Ryan J Davis, Markus Welcker, Bruce E Clurman. Cancer Cell 2014
235
18

FBXW7/hCDC4 is a general tumor suppressor in human cancer.
Shahab Akhoondi, Dahui Sun, Natalie von der Lehr, Sophia Apostolidou, Kathleen Klotz, Alena Maljukova, Diana Cepeda, Heidi Fiegl, Dimitra Dafou, Christian Marth,[...]. Cancer Res 2007
369
18

Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene.
Jian-Hua Mao, Jesus Perez-Losada, Di Wu, Reyno Delrosario, Ryosuke Tsunematsu, Keiichi I Nakayama, Ken Brown, Sheila Bryson, Allan Balmain. Nature 2004
306
16

FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression.
Jian-Hua Mao, Il-Jin Kim, Di Wu, Joan Climent, Hio Chung Kang, Reyno DelRosario, Allan Balmain. Science 2008
311
16

SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
Hiroyuki Inuzuka, Shavali Shaik, Ichiro Onoyama, Daming Gao, Alan Tseng, Richard S Maser, Bo Zhai, Lixin Wan, Alejandro Gutierrez, Alan W Lau,[...]. Nature 2011
474
16

p53-Altered FBXW7 expression determines poor prognosis in gastric cancer cases.
Takehiko Yokobori, Koshi Mimori, Masaaki Iwatsuki, Hideshi Ishii, Ichiro Onoyama, Takeo Fukagawa, Hiroyuki Kuwano, Keiichi I Nakayama, Masaki Mori. Cancer Res 2009
120
15

The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation.
Markus Welcker, Amir Orian, Jianping Jin, Jonathan E Grim, J Wade Harper, Robert N Eisenman, Bruce E Clurman. Proc Natl Acad Sci U S A 2004
651
15

The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability.
Bryan King, Thomas Trimarchi, Linsey Reavie, Luyao Xu, Jasper Mullenders, Panagiotis Ntziachristos, Beatriz Aranda-Orgilles, Arianne Perez-Garcia, Junwei Shi, Christopher Vakoc,[...]. Cell 2013
222
14

FBXW7: a critical tumor suppressor of human cancers.
Chien-Hung Yeh, Marcia Bellon, Christophe Nicot. Mol Cancer 2018
199
14

Ablation of Fbxw7 eliminates leukemia-initiating cells by preventing quiescence.
Shoichiro Takeishi, Akinobu Matsumoto, Ichiro Onoyama, Kazuhito Naka, Atsushi Hirao, Keiichi I Nakayama. Cancer Cell 2013
114
12

Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL.
Sahoko Matsuoka, Yuichi Oike, Ichiro Onoyama, Atsushi Iwama, Fumio Arai, Keiyo Takubo, Yoichi Mashimo, Hideyuki Oguro, Eriko Nitta, Keisuke Ito,[...]. Genes Dev 2008
143
12

Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomerase.
Sang-Hyun Min, Alan W Lau, Tae Ho Lee, Hiroyuki Inuzuka, Shuo Wei, Pengyu Huang, Shavali Shaik, Daniel Yenhong Lee, Greg Finn, Martin Balastik,[...]. Mol Cell 2012
119
12

Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia.
V Kumar, R Palermo, C Talora, A F Campese, S Checquolo, D Bellavia, L Tottone, G Testa, E Miele, S Indraccolo,[...]. Leukemia 2014
128
11

Sequential expression of miR-182 and miR-503 cooperatively targets FBXW7, contributing to the malignant transformation of colon adenoma to adenocarcinoma.
Lihua Li, Aaron L Sarver, Rohini Khatri, Praveensingh B Hajeri, Iris Kamenev, Amy J French, Stephen N Thibodeau, Clifford J Steer, Subbaya Subramanian. J Pathol 2014
49
18

F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor.
Rocio Sancho, Anett Jandke, Hayley Davis, Markus E Diefenbacher, Ian Tomlinson, Axel Behrens. Gastroenterology 2010
93
11

Ubiquitin ligases: cell-cycle control and cancer.
Keiichi I Nakayama, Keiko Nakayama. Nat Rev Cancer 2006
11

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line.
H Strohmaier, C H Spruck, P Kaiser, K A Won, O Sangfelt, S I Reed. Nature 2001
489
11

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors.
Jennifer O'Neil, Jonathan Grim, Peter Strack, Sudhir Rao, Deanne Tibbitts, Christopher Winter, James Hardwick, Markus Welcker, Jules P Meijerink, Rob Pieters,[...]. J Exp Med 2007
499
11

The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia.
Benjamin J Thompson, Silvia Buonamici, Maria Luisa Sulis, Teresa Palomero, Tomas Vilimas, Giuseppe Basso, Adolfo Ferrando, Iannis Aifantis. J Exp Med 2007
351
11

FBXW7 modulates cellular stress response and metastatic potential through ​HSF1 post-translational modification.
Nikos Kourtis, Rana S Moubarak, Beatriz Aranda-Orgilles, Kevin Lui, Iraz T Aydin, Thomas Trimarchi, Farbod Darvishian, Christine Salvaggio, Judy Zhong, Kamala Bhatt,[...]. Nat Cell Biol 2015
74
12

Fbw7 dimerization determines the specificity and robustness of substrate degradation.
Markus Welcker, Elizabeth A Larimore, Jherek Swanger, Maria T Bengoechea-Alonso, Jonathan E Grim, Johan Ericsson, Ning Zheng, Bruce E Clurman. Genes Dev 2013
66
13

Fbxw7α- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma.
Luca Busino, Scott E Millman, Luigi Scotto, Christos A Kyratsous, Venkatesha Basrur, Owen O'Connor, Alexander Hoffmann, Kojo S Elenitoba-Johnson, Michele Pagano. Nat Cell Biol 2012
133
11

Roles of F-box proteins in cancer.
Zhiwei Wang, Pengda Liu, Hiroyuki Inuzuka, Wenyi Wei. Nat Rev Cancer 2014
302
10

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase.
D M Koepp, L K Schaefer, X Ye, K Keyomarsi, C Chu, J W Harper, S J Elledge. Science 2001
628
10

Fbxw7-dependent degradation of Notch is required for control of "stemness" and neuronal-glial differentiation in neural stem cells.
Akinobu Matsumoto, Ichiro Onoyama, Takehiko Sunabori, Ryoichiro Kageyama, Hideyuki Okano, Keiichi I Nakayama. J Biol Chem 2011
80
10

Overexpression of microRNA-223 regulates the ubiquitin ligase FBXW7 in oesophageal squamous cell carcinoma.
J Kurashige, M Watanabe, M Iwatsuki, K Kinoshita, S Saito, Y Hiyoshi, H Kamohara, Y Baba, K Mimori, H Baba. Br J Cancer 2012
113
10

FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation.
Roya Babaei-Jadidi, Ningning Li, Anas Saadeddin, Bradley Spencer-Dene, Anett Jandke, Belal Muhammad, ElSayed E Ibrahim, Ranjithmenon Muraleedharan, Mohammed Abuzinadah, Hayley Davis,[...]. J Exp Med 2011
132
10

The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase.
Wenyi Wei, Jianping Jin, Susanne Schlisio, J Wade Harper, William G Kaelin. Cancer Cell 2005
321
10

Regulation of c-Myc ubiquitination controls chronic myelogenous leukemia initiation and progression.
Linsey Reavie, Shannon M Buckley, Evangelia Loizou, Shoichiro Takeishi, Beatriz Aranda-Orgilles, Delphine Ndiaye-Lobry, Omar Abdel-Wahab, Sherif Ibrahim, Keiichi I Nakayama, Iannis Aifantis. Cancer Cell 2013
85
10

Inactivation of FBXW7/hCDC4-β expression by promoter hypermethylation is associated with favorable prognosis in primary breast cancer.
Shahab Akhoondi, Linda Lindström, Martin Widschwendter, Martin Corcoran, Jonas Bergh, Charles Spruck, Dan Grandér, Olle Sangfelt. Breast Cancer Res 2010
60
13

hCDC4b, a regulator of cyclin E, as a direct transcriptional target of p53.
Takashi Kimura, Mitsukazu Gotoh, Yusuke Nakamura, Hirofumi Arakawa. Cancer Sci 2003
93
10


Oncogenic mutations in the FBXW7 gene of adult T-cell leukemia patients.
Chien-Hung Yeh, Marcia Bellon, Joanna Pancewicz-Wojtkiewicz, Christophe Nicot. Proc Natl Acad Sci U S A 2016
52
15

MiRNA-27a controls FBW7/hCDC4-dependent cyclin E degradation and cell cycle progression.
Mikael Lerner, Josefin Lundgren, Shahab Akhoondi, Angelina Jahn, Hwee-Fang Ng, Farhad Akbari Moqadam, Joachim A F Oude Vrielink, Reuven Agami, Monique L Den Boer, Dan Grandér,[...]. Cell Cycle 2011
92
9

ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer.
Shunrong Ji, Yi Qin, Si Shi, Xiangyuan Liu, Hongli Hu, Hu Zhou, Jing Gao, Bo Zhang, Wenyan Xu, Jiang Liu,[...]. Cell Res 2015
89
9

Loss of FBXW7, a cell cycle regulating gene, in colorectal cancer: clinical significance.
Masaaki Iwatsuki, Koshi Mimori, Hideshi Ishii, Takehiko Yokobori, Yasushi Takatsuno, Tetsuya Sato, Hiroyuki Toh, Ichiro Onoyama, Keiichi I Nakayama, Hideo Baba,[...]. Int J Cancer 2010
111
9

Aberrant regulation of FBW7 in cancer.
Lixia Wang, Xiantao Ye, Yueyong Liu, Wenyi Wei, Zhiwei Wang. Oncotarget 2014
69
10

Mechanisms and function of substrate recruitment by F-box proteins.
Jeffrey R Skaar, Julia K Pagan, Michele Pagano. Nat Rev Mol Cell Biol 2013
413
9

Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun.
Joerg D Hoeck, Anett Jandke, Sophia M Blake, Emma Nye, Bradley Spencer-Dene, Sebastian Brandner, Axel Behrens. Nat Neurosci 2010
130
9

The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling.
Abdolrahman S Nateri, Lluís Riera-Sans, Clive Da Costa, Axel Behrens. Science 2004
300
9

Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7.
Ingrid E Wertz, Saritha Kusam, Cynthia Lam, Toru Okamoto, Wendy Sandoval, Daniel J Anderson, Elizabeth Helgason, James A Ernst, Mike Eby, Jinfeng Liu,[...]. Nature 2011
575
9

Fbxw7 is an independent prognostic marker and induces apoptosis and growth arrest by regulating YAP abundance in hepatocellular carcinoma.
Kangsheng Tu, Wei Yang, Chao Li, Xin Zheng, Zhongtang Lu, Cheng Guo, Yingmin Yao, Qingguang Liu. Mol Cancer 2014
122
9

Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis.
Ichiro Onoyama, Ryosuke Tsunematsu, Akinobu Matsumoto, Taichi Kimura, Ignacio Moreno de Alborán, Keiko Nakayama, Keiichi I Nakayama. J Exp Med 2007
149
9

Upregulation of miR-27a contributes to the malignant transformation of human bronchial epithelial cells induced by SV40 small T antigen.
Q Wang, D-C Li, Z-F Li, C-X Liu, Y-M Xiao, B Zhang, X-D Li, J Zhao, L-P Chen, X-M Xing,[...]. Oncogene 2011
66
10


Fbw7 repression by hes5 creates a feedback loop that modulates Notch-mediated intestinal and neural stem cell fate decisions.
Rocio Sancho, Sophia M Blake, Christian Tendeng, Bruce E Clurman, Julian Lewis, Axel Behrens. PLoS Biol 2013
40
17

Presenilin modulates EGFR signaling and cell transformation by regulating the ubiquitin ligase Fbw7.
V Rocher-Ros, S Marco, J-H Mao, S Gines, D Metzger, P Chambon, A Balmain, C A Saura. Oncogene 2010
35
20

FBXW7α attenuates inflammatory signalling by downregulating C/EBPδ and its target gene Tlr4.
Kuppusamy Balamurugan, Shikha Sharan, Kimberly D Klarmann, Youhong Zhang, Vincenzo Coppola, Glenn H Summers, Thierry Roger, Deborah K Morrison, Jonathan R Keller, Esta Sterneck. Nat Commun 2013
62
11


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.