A citation-based method for searching scientific literature

Eva M Palsson-McDermott, Anne M Curtis, Gautam Goel, Mario A R Lauterbach, Frederick J Sheedy, Laura E Gleeson, Mirjam W M van den Bosch, Susan R Quinn, Raquel Domingo-Fernandez, Daniel G W Johnston, Jian-Kang Jiang, William J Israelsen, Joseph Keane, Craig Thomas, Clary Clish, Matthew Vander Heiden, Ramnik J Xavier, Luke A J O'Neill. Cell Metab 2015
Times Cited: 530







List of co-cited articles
1049 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Succinate is an inflammatory signal that induces IL-1β through HIF-1α.
G M Tannahill, A M Curtis, J Adamik, E M Palsson-McDermott, A F McGettrick, G Goel, C Frezza, N J Bernard, B Kelly, N H Foley,[...]. Nature 2013
49

Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization.
Abhishek K Jha, Stanley Ching-Cheng Huang, Alexey Sergushichev, Vicky Lampropoulou, Yulia Ivanova, Ekaterina Loginicheva, Karina Chmielewski, Kelly M Stewart, Juliet Ashall, Bart Everts,[...]. Immunity 2015
864
31

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages.
Evanna L Mills, Beth Kelly, Angela Logan, Ana S H Costa, Mukund Varma, Clare E Bryant, Panagiotis Tourlomousis, J Henry M Däbritz, Eyal Gottlieb, Isabel Latorre,[...]. Cell 2016
813
24

Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation.
Vicky Lampropoulou, Alexey Sergushichev, Monika Bambouskova, Sharmila Nair, Emma E Vincent, Ekaterina Loginicheva, Luisa Cervantes-Barragan, Xiucui Ma, Stanley Ching-Cheng Huang, Takla Griss,[...]. Cell Metab 2016
532
20

PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation.
Min Xie, Yan Yu, Rui Kang, Shan Zhu, Liangchun Yang, Ling Zeng, Xiaofang Sun, Minghua Yang, Timothy R Billiar, Haichao Wang,[...]. Nat Commun 2016
199
20

α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming.
Pu-Ste Liu, Haiping Wang, Xiaoyun Li, Tung Chao, Tony Teav, Stefan Christen, Giusy Di Conza, Wan-Chen Cheng, Chih-Hung Chou, Magdalena Vavakova,[...]. Nat Immunol 2017
352
20

Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1.
Weibo Luo, Hongxia Hu, Ryan Chang, Jun Zhong, Matthew Knabel, Robert O'Meally, Robert N Cole, Akhilesh Pandey, Gregg L Semenza. Cell 2011
867
18


Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages.
Stanley Ching-Cheng Huang, Bart Everts, Yulia Ivanova, David O'Sullivan, Marcia Nascimento, Amber M Smith, Wandy Beatty, Latisha Love-Gregory, Wing Y Lam, Christina M O'Neill,[...]. Nat Immunol 2014
591
17

PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis.
Liangchun Yang, Min Xie, Minghua Yang, Yan Yu, Shan Zhu, Wen Hou, Rui Kang, Michael T Lotze, Timothy R Billiar, Haichao Wang,[...]. Nat Commun 2014
235
17

A guide to immunometabolism for immunologists.
Luke A J O'Neill, Rigel J Kishton, Jeff Rathmell. Nat Rev Immunol 2016
16

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Evanna L Mills, Dylan G Ryan, Hiran A Prag, Dina Dikovskaya, Deepthi Menon, Zbigniew Zaslona, Mark P Jedrychowski, Ana S H Costa, Maureen Higgins, Emily Hams,[...]. Nature 2018
557
16

TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation.
Bart Everts, Eyal Amiel, Stanley Ching-Cheng Huang, Amber M Smith, Chih-Hao Chang, Wing Y Lam, Veronika Redmann, Tori C Freitas, Julianna Blagih, Gerritje J W van der Windt,[...]. Nat Immunol 2014
590
15

Substrate fate in activated macrophages: a comparison between innate, classic, and alternative activation.
Juan-Carlos Rodríguez-Prados, Paqui G Través, Jimena Cuenca, Daniel Rico, Julián Aragonés, Paloma Martín-Sanz, Marta Cascante, Lisardo Boscá. J Immunol 2010
576
15

Immunometabolism governs dendritic cell and macrophage function.
Luke A J O'Neill, Edward J Pearce. J Exp Med 2016
762
14

Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production.
Alessandro Michelucci, Thekla Cordes, Jenny Ghelfi, Arnaud Pailot, Norbert Reiling, Oliver Goldmann, Tina Binz, André Wegner, Aravind Tallam, Antonio Rausell,[...]. Proc Natl Acad Sci U S A 2013
477
14

Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages.
Jan Van den Bossche, Jeroen Baardman, Natasja A Otto, Saskia van der Velden, Annette E Neele, Susan M van den Berg, Rosario Luque-Martin, Hung-Jen Chen, Marieke C S Boshuizen, Mohamed Ahmed,[...]. Cell Rep 2016
326
14

Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation.
Stanley Ching-Cheng Huang, Amber M Smith, Bart Everts, Marco Colonna, Erika L Pearce, Joel D Schilling, Edward J Pearce. Immunity 2016
283
14

Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity.
Rob J W Arts, Boris Novakovic, Rob Ter Horst, Agostinho Carvalho, Siroon Bekkering, Ekta Lachmandas, Fernando Rodrigues, Ricardo Silvestre, Shih-Chin Cheng, Shuang-Yin Wang,[...]. Cell Metab 2016
363
13

The sedoheptulose kinase CARKL directs macrophage polarization through control of glucose metabolism.
Arvand Haschemi, Paul Kosma, Lars Gille, Charles R Evans, Charles F Burant, Philipp Starkl, Bernhard Knapp, Robert Haas, Johannes A Schmid, Christoph Jandl,[...]. Cell Metab 2012
338
13

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS.
A Phillip West, Igor E Brodsky, Christoph Rahner, Dong Kyun Woo, Hediye Erdjument-Bromage, Paul Tempst, Matthew C Walsh, Yongwon Choi, Gerald S Shadel, Sankar Ghosh. Nature 2011
916
13

Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages.
W K Eddie Ip, Namiko Hoshi, Dror S Shouval, Scott Snapper, Ruslan Medzhitov. Science 2017
540
13

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid.
Oscar R Colegio, Ngoc-Quynh Chu, Alison L Szabo, Thach Chu, Anne Marie Rhebergen, Vikram Jairam, Nika Cyrus, Carolyn E Brokowski, Stephanie C Eisenbarth, Gillian M Phillips,[...]. Nature 2014
13

Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity.
Stefano Angiari, Marah C Runtsch, Caroline E Sutton, Eva M Palsson-McDermott, Beth Kelly, Nisha Rana, Harry Kane, Gina Papadopoulou, Erika L Pearce, Kingston H G Mills,[...]. Cell Metab 2020
84
15

Metabolic reprogramming of macrophages: glucose transporter 1 (GLUT1)-mediated glucose metabolism drives a proinflammatory phenotype.
Alex J Freemerman, Amy R Johnson, Gina N Sacks, J Justin Milner, Erin L Kirk, Melissa A Troester, Andrew N Macintyre, Pankuri Goraksha-Hicks, Jeffery C Rathmell, Liza Makowski. J Biol Chem 2014
411
13

Glycolytic Stimulation Is Not a Requirement for M2 Macrophage Differentiation.
Feilong Wang, Song Zhang, Ivan Vuckovic, Ryounghoon Jeon, Amir Lerman, Clifford D Folmes, Petras P Dzeja, Joerg Herrmann. Cell Metab 2018
114
13

Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation.
Divya Vats, Lata Mukundan, Justin I Odegaard, Lina Zhang, Kristi L Smith, Christine R Morel, Roger A Wagner, David R Greaves, Peter J Murray, Ajay Chawla. Cell Metab 2006
836
13

Metabolic regulation of gene expression by histone lactylation.
Di Zhang, Zhanyun Tang, He Huang, Guolin Zhou, Chang Cui, Yejing Weng, Wenchao Liu, Sunjoo Kim, Sangkyu Lee, Mathew Perez-Neut,[...]. Nature 2019
415
13

mTOR- and HIF-1α-mediated aerobic glycolysis as metabolic basis for trained immunity.
Shih-Chin Cheng, Jessica Quintin, Robert A Cramer, Kelly M Shepardson, Sadia Saeed, Vinod Kumar, Evangelos J Giamarellos-Bourboulis, Joost H A Martens, Nagesha Appukudige Rao, Ali Aghajanirefah,[...]. Science 2014
949
12

Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance.
Justin I Odegaard, Roberto R Ricardo-Gonzalez, Matthew H Goforth, Christine R Morel, Vidya Subramanian, Lata Mukundan, Alex Red Eagle, Divya Vats, Frank Brombacher, Anthony W Ferrante,[...]. Nature 2007
12

HIF-1alpha is essential for myeloid cell-mediated inflammation.
Thorsten Cramer, Yuji Yamanishi, Björn E Clausen, Irmgard Förster, Rafal Pawlinski, Nigel Mackman, Volker H Haase, Rudolf Jaenisch, Maripat Corr, Victor Nizet,[...]. Cell 2003
11

Microbial stimulation of different Toll-like receptor signalling pathways induces diverse metabolic programmes in human monocytes.
Ekta Lachmandas, Lily Boutens, Jacqueline M Ratter, Anneke Hijmans, Guido J Hooiveld, Leo A B Joosten, Richard J Rodenburg, Jack A M Fransen, Riekelt H Houtkooper, Reinout van Crevel,[...]. Nat Microbiol 2016
155
11

Macrophage Immunometabolism: Where Are We (Going)?
Jan Van den Bossche, Luke A O'Neill, Deepthi Menon. Trends Immunol 2017
397
11

Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis.
Erika M Palmieri, Alessio Menga, Rosa Martín-Pérez, Annamaria Quinto, Carla Riera-Domingo, Giacoma De Tullio, Douglas C Hooper, Wouter H Lamers, Bart Ghesquière, Daniel W McVicar,[...]. Cell Rep 2017
141
11

The glycolytic enzyme PKM2 bridges metabolic and inflammatory dysfunction in coronary artery disease.
Tsuyoshi Shirai, Rafal R Nazarewicz, Barbara B Wallis, Rolando E Yanes, Ryu Watanabe, Marc Hilhorst, Lu Tian, David G Harrison, John C Giacomini, Themistocles L Assimes,[...]. J Exp Med 2016
259
11

HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells.
Lewis Z Shi, Ruoning Wang, Gonghua Huang, Peter Vogel, Geoffrey Neale, Douglas R Green, Hongbo Chi. J Exp Med 2011
10

Nitric Oxide Modulates Metabolic Remodeling in Inflammatory Macrophages through TCA Cycle Regulation and Itaconate Accumulation.
Jade D Bailey, Marina Diotallevi, Thomas Nicol, Eileen McNeill, Andrew Shaw, Surawee Chuaiphichai, Ashley Hale, Anna Starr, Manasi Nandi, Elena Stylianou,[...]. Cell Rep 2019
76
13

NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha.
Jordi Rius, Monica Guma, Christian Schachtrup, Katerina Akassoglou, Annelies S Zinkernagel, Victor Nizet, Randall S Johnson, Gabriel G Haddad, Michael Karin. Nature 2008
10

The mitochondrial citrate carrier: a new player in inflammation.
Vittoria Infantino, Paolo Convertini, Liana Cucci, Maria Antonietta Panaro, Maria Antonietta Di Noia, Rosa Calvello, Ferdinando Palmieri, Vito Iacobazzi. Biochem J 2011
225
10

Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels.
Thekla Cordes, Martina Wallace, Alessandro Michelucci, Ajit S Divakaruni, Sean C Sapcariu, Carole Sousa, Haruhiko Koseki, Pedro Cabrales, Anne N Murphy, Karsten Hiller,[...]. J Biol Chem 2016
216
10

Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase.
Erika M Palmieri, Marieli Gonzalez-Cotto, Walter A Baseler, Luke C Davies, Bart Ghesquière, Nunziata Maio, Christopher M Rice, Tracey A Rouault, Teresa Cassel, Richard M Higashi,[...]. Nat Commun 2020
92
9

Posttranscriptional control of T cell effector function by aerobic glycolysis.
Chih-Hao Chang, Jonathan D Curtis, Leonard B Maggi, Brandon Faubert, Alejandro V Villarino, David O'Sullivan, Stanley Ching-Cheng Huang, Gerritje J W van der Windt, Julianna Blagih, Jing Qiu,[...]. Cell 2013
9

Macrophage activation and polarization: nomenclature and experimental guidelines.
Peter J Murray, Judith E Allen, Subhra K Biswas, Edward A Fisher, Derek W Gilroy, Sergij Goerdt, Siamon Gordon, John A Hamilton, Lionel B Ivashkiv, Toby Lawrence,[...]. Immunity 2014
9

Toll-like Receptor Signaling Rewires Macrophage Metabolism and Promotes Histone Acetylation via ATP-Citrate Lyase.
Mario A Lauterbach, Jasmin E Hanke, Magdalini Serefidou, Matthew S J Mangan, Carl-Christian Kolbe, Timo Hess, Maximilian Rothe, Romina Kaiser, Florian Hoss, Jan Gehlen,[...]. Immunity 2019
96
9

Pyruvate dehydrogenase kinase 1 participates in macrophage polarization via regulating glucose metabolism.
Zheng Tan, Na Xie, Huachun Cui, Douglas R Moellering, Edward Abraham, Victor J Thannickal, Gang Liu. J Immunol 2015
161
9

Krebs Cycle Reborn in Macrophage Immunometabolism.
Dylan G Ryan, Luke A J O'Neill. Annu Rev Immunol 2020
75
12

SIRT5 Desuccinylates and Activates Pyruvate Kinase M2 to Block Macrophage IL-1β Production and to Prevent DSS-Induced Colitis in Mice.
Fang Wang, Ke Wang, Wei Xu, Shimin Zhao, Dan Ye, Yi Wang, Ying Xu, Lisha Zhou, Yiwei Chu, Cuiping Zhang,[...]. Cell Rep 2017
115
9

Metabolic Induction of Trained Immunity through the Mevalonate Pathway.
Siroon Bekkering, Rob J W Arts, Boris Novakovic, Ioannis Kourtzelis, Charlotte D C C van der Heijden, Yang Li, Calin D Popa, Rob Ter Horst, Julia van Tuijl, Romana T Netea-Maier,[...]. Cell 2018
283
8

ATP-citrate lyase is essential for macrophage inflammatory response.
Vittoria Infantino, Vito Iacobazzi, Ferdinando Palmieri, Alessio Menga. Biochem Biophys Res Commun 2013
144
8

Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells.
Bart Everts, Eyal Amiel, Gerritje J W van der Windt, Tori C Freitas, Robert Chott, Kevin E Yarasheski, Erika L Pearce, Edward J Pearce. Blood 2012
345
8


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.