Rachel Litman Flynn, Kelli E Cox, Maya Jeitany, Hiroaki Wakimoto, Alysia R Bryll, Neil J Ganem, Francesca Bersani, Jose R Pineda, Mario L Suvà, Cyril H Benes, Daniel A Haber, Francois D Boussin, Lee Zou. Science 2015
Times Cited: 240
Times Cited: 240
Times Cited
Times Co-cited
Similarity
Altered telomeres in tumors with ATRX and DAXX mutations.
Christopher M Heaphy, Roeland F de Wilde, Yuchen Jiao, Alison P Klein, Barish H Edil, Chanjuan Shi, Chetan Bettegowda, Fausto J Rodriguez, Charles G Eberhart, Sachidanand Hebbar,[...]. Science 2011
Christopher M Heaphy, Roeland F de Wilde, Yuchen Jiao, Alison P Klein, Barish H Edil, Chanjuan Shi, Chetan Bettegowda, Fausto J Rodriguez, Charles G Eberhart, Sachidanand Hebbar,[...]. Science 2011
39
Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway.
Courtney A Lovejoy, Wendi Li, Steven Reisenweber, Supawat Thongthip, Joanne Bruno, Titia de Lange, Saurav De, John H J Petrini, Patricia A Sung, Maria Jasin,[...]. PLoS Genet 2012
Courtney A Lovejoy, Wendi Li, Steven Reisenweber, Supawat Thongthip, Joanne Bruno, Titia de Lange, Saurav De, John H J Petrini, Patricia A Sung, Maria Jasin,[...]. PLoS Genet 2012
32
Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes.
Christopher M Heaphy, Andrea P Subhawong, Seung-Mo Hong, Michael G Goggins, Elizabeth A Montgomery, Edward Gabrielson, George J Netto, Jonathan I Epstein, Tamara L Lotan, William H Westra,[...]. Am J Pathol 2011
Christopher M Heaphy, Andrea P Subhawong, Seung-Mo Hong, Michael G Goggins, Elizabeth A Montgomery, Edward Gabrielson, George J Netto, Jonathan I Epstein, Tamara L Lotan, William H Westra,[...]. Am J Pathol 2011
31
Alternative lengthening of telomeres: models, mechanisms and implications.
Anthony J Cesare, Roger R Reddel. Nat Rev Genet 2010
Anthony J Cesare, Roger R Reddel. Nat Rev Genet 2010
30
RNaseH1 regulates TERRA-telomeric DNA hybrids and telomere maintenance in ALT tumour cells.
Rajika Arora, Yongwoo Lee, Harry Wischnewski, Catherine M Brun, Tobias Schwarz, Claus M Azzalin. Nat Commun 2014
Rajika Arora, Yongwoo Lee, Harry Wischnewski, Catherine M Brun, Tobias Schwarz, Claus M Azzalin. Nat Commun 2014
28
Telomerase-negative immortalized human cells contain a novel type of promyelocytic leukemia (PML) body.
T R Yeager, A A Neumann, A Englezou, L I Huschtscha, J R Noble, R R Reddel. Cancer Res 1999
T R Yeager, A A Neumann, A Englezou, L I Huschtscha, J R Noble, R R Reddel. Cancer Res 1999
27
DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telomeres activity.
Jeremy D Henson, Ying Cao, Lily I Huschtscha, Andy C Chang, Amy Y M Au, Hilda A Pickett, Roger R Reddel. Nat Biotechnol 2009
Jeremy D Henson, Ying Cao, Lily I Huschtscha, Andy C Chang, Amy Y M Au, Hilda A Pickett, Roger R Reddel. Nat Biotechnol 2009
26
Break-induced telomere synthesis underlies alternative telomere maintenance.
Robert L Dilley, Priyanka Verma, Nam Woo Cho, Harrison D Winters, Anne R Wondisford, Roger A Greenberg. Nature 2016
Robert L Dilley, Priyanka Verma, Nam Woo Cho, Harrison D Winters, Anne R Wondisford, Roger A Greenberg. Nature 2016
24
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma.
Jeremy Schwartzentruber, Andrey Korshunov, Xiao-Yang Liu, David T W Jones, Elke Pfaff, Karine Jacob, Dominik Sturm, Adam M Fontebasso, Dong-Anh Khuong Quang, Martje Tönjes,[...]. Nature 2012
Jeremy Schwartzentruber, Andrey Korshunov, Xiao-Yang Liu, David T W Jones, Elke Pfaff, Karine Jacob, Dominik Sturm, Adam M Fontebasso, Dong-Anh Khuong Quang, Martje Tönjes,[...]. Nature 2012
21
Suppression of the alternative lengthening of telomere pathway by the chromatin remodelling factor ATRX.
David Clynes, Clare Jelinska, Barbara Xella, Helena Ayyub, Caroline Scott, Matthew Mitson, Stephen Taylor, Douglas R Higgs, Richard J Gibbons. Nat Commun 2015
David Clynes, Clare Jelinska, Barbara Xella, Helena Ayyub, Caroline Scott, Matthew Mitson, Stephen Taylor, Douglas R Higgs, Richard J Gibbons. Nat Commun 2015
19
Cancer Cells with Alternative Lengthening of Telomeres Do Not Display a General Hypersensitivity to ATR Inhibition.
Katharina I Deeg, Inn Chung, Caroline Bauer, Karsten Rippe. Front Oncol 2016
Katharina I Deeg, Inn Chung, Caroline Bauer, Karsten Rippe. Front Oncol 2016
73
Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1.
Roderick J O'Sullivan, Nausica Arnoult, Daniel H Lackner, Liana Oganesian, Candy Haggblom, Armelle Corpet, Genevieve Almouzni, Jan Karlseder. Nat Struct Mol Biol 2014
Roderick J O'Sullivan, Nausica Arnoult, Daniel H Lackner, Liana Oganesian, Candy Haggblom, Armelle Corpet, Genevieve Almouzni, Jan Karlseder. Nat Struct Mol Biol 2014
18
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal.
Patrick J Killela, Zachary J Reitman, Yuchen Jiao, Chetan Bettegowda, Nishant Agrawal, Luis A Diaz, Allan H Friedman, Henry Friedman, Gary L Gallia, Beppino C Giovanella,[...]. Proc Natl Acad Sci U S A 2013
Patrick J Killela, Zachary J Reitman, Yuchen Jiao, Chetan Bettegowda, Nishant Agrawal, Luis A Diaz, Allan H Friedman, Henry Friedman, Gary L Gallia, Beppino C Giovanella,[...]. Proc Natl Acad Sci U S A 2013
18
Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines.
T M Bryan, A Englezou, L Dalla-Pozza, M A Dunham, R R Reddel. Nat Med 1997
T M Bryan, A Englezou, L Dalla-Pozza, M A Dunham, R R Reddel. Nat Med 1997
17
Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends.
Claus M Azzalin, Patrick Reichenbach, Lela Khoriauli, Elena Giulotto, Joachim Lingner. Science 2007
Claus M Azzalin, Patrick Reichenbach, Lela Khoriauli, Elena Giulotto, Joachim Lingner. Science 2007
17
Alternative Lengthening of Telomeres is characterized by reduced compaction of telomeric chromatin.
Harikleia Episkopou, Irena Draskovic, Amandine Van Beneden, Gaëlle Tilman, Marina Mattiussi, Matthieu Gobin, Nausica Arnoult, Arturo Londoño-Vallejo, Anabelle Decottignies. Nucleic Acids Res 2014
Harikleia Episkopou, Irena Draskovic, Amandine Van Beneden, Gaëlle Tilman, Marina Mattiussi, Matthieu Gobin, Nausica Arnoult, Arturo Londoño-Vallejo, Anabelle Decottignies. Nucleic Acids Res 2014
18
Interchromosomal homology searches drive directional ALT telomere movement and synapsis.
Nam Woo Cho, Robert L Dilley, Michael A Lampson, Roger A Greenberg. Cell 2014
Nam Woo Cho, Robert L Dilley, Michael A Lampson, Roger A Greenberg. Cell 2014
17
ATRX represses alternative lengthening of telomeres.
Christine E Napier, Lily I Huschtscha, Adam Harvey, Kylie Bower, Jane R Noble, Eric A Hendrickson, Roger R Reddel. Oncotarget 2015
Christine E Napier, Lily I Huschtscha, Adam Harvey, Kylie Bower, Jane R Noble, Eric A Hendrickson, Roger R Reddel. Oncotarget 2015
21
Assaying and investigating Alternative Lengthening of Telomeres activity in human cells and cancers.
Jeremy D Henson, Roger R Reddel. FEBS Lett 2010
Jeremy D Henson, Roger R Reddel. FEBS Lett 2010
16
Alternative Lengthening of Telomeres Mediated by Mitotic DNA Synthesis Engages Break-Induced Replication Processes.
Jaewon Min, Woodring E Wright, Jerry W Shay. Mol Cell Biol 2017
Jaewon Min, Woodring E Wright, Jerry W Shay. Mol Cell Biol 2017
20
Telomere maintenance by recombination in human cells.
M A Dunham, A A Neumann, C L Fasching, R R Reddel. Nat Genet 2000
M A Dunham, A A Neumann, C L Fasching, R R Reddel. Nat Genet 2000
16
Alternative Lengthening of Telomeres through Two Distinct Break-Induced Replication Pathways.
Jia-Min Zhang, Tribhuwan Yadav, Jian Ouyang, Li Lan, Lee Zou. Cell Rep 2019
Jia-Min Zhang, Tribhuwan Yadav, Jian Ouyang, Li Lan, Lee Zou. Cell Rep 2019
21
Systematic analysis of telomere length and somatic alterations in 31 cancer types.
Floris P Barthel, Wei Wei, Ming Tang, Emmanuel Martinez-Ledesma, Xin Hu, Samirkumar B Amin, Kadir C Akdemir, Sahil Seth, Xingzhi Song, Qianghu Wang,[...]. Nat Genet 2017
Floris P Barthel, Wei Wei, Ming Tang, Emmanuel Martinez-Ledesma, Xin Hu, Samirkumar B Amin, Kadir C Akdemir, Sahil Seth, Xingzhi Song, Qianghu Wang,[...]. Nat Genet 2017
15
15
Alternative Lengthening of Telomeres: DNA Repair Pathways Converge.
Alexander P Sobinoff, Hilda A Pickett. Trends Genet 2017
Alexander P Sobinoff, Hilda A Pickett. Trends Genet 2017
23
Molecular mechanisms of activity and derepression of alternative lengthening of telomeres.
Hilda A Pickett, Roger R Reddel. Nat Struct Mol Biol 2015
Hilda A Pickett, Roger R Reddel. Nat Struct Mol Biol 2015
14
Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication.
Agnel Sfeir, Settapong T Kosiyatrakul, Dirk Hockemeyer, Sheila L MacRae, Jan Karlseder, Carl L Schildkraut, Titia de Lange. Cell 2009
Agnel Sfeir, Settapong T Kosiyatrakul, Dirk Hockemeyer, Sheila L MacRae, Jan Karlseder, Carl L Schildkraut, Titia de Lange. Cell 2009
14
BLM and SLX4 play opposing roles in recombination-dependent replication at human telomeres.
Alexander P Sobinoff, Joshua Am Allen, Axel A Neumann, Sile F Yang, Monica E Walsh, Jeremy D Henson, Roger R Reddel, Hilda A Pickett. EMBO J 2017
Alexander P Sobinoff, Joshua Am Allen, Axel A Neumann, Sile F Yang, Monica E Walsh, Jeremy D Henson, Roger R Reddel, Hilda A Pickett. EMBO J 2017
23
Alternative lengthening of human telomeres is a conservative DNA replication process with features of break-induced replication.
Fani-Marlen Roumelioti, Sotirios K Sotiriou, Vasiliki Katsini, Maria Chiourea, Thanos D Halazonetis, Sarantis Gagos. EMBO Rep 2016
Fani-Marlen Roumelioti, Sotirios K Sotiriou, Vasiliki Katsini, Maria Chiourea, Thanos D Halazonetis, Sarantis Gagos. EMBO Rep 2016
18
Telomerase activation by genomic rearrangements in high-risk neuroblastoma.
Martin Peifer, Falk Hertwig, Frederik Roels, Daniel Dreidax, Moritz Gartlgruber, Roopika Menon, Andrea Krämer, Justin L Roncaioli, Frederik Sand, Johannes M Heuckmann,[...]. Nature 2015
Martin Peifer, Falk Hertwig, Frederik Roels, Daniel Dreidax, Moritz Gartlgruber, Roopika Menon, Andrea Krämer, Justin L Roncaioli, Frederik Sand, Johannes M Heuckmann,[...]. Nature 2015
13
Telomere elongation in immortal human cells without detectable telomerase activity.
T M Bryan, A Englezou, J Gupta, S Bacchetti, R R Reddel. EMBO J 1995
T M Bryan, A Englezou, J Gupta, S Bacchetti, R R Reddel. EMBO J 1995
13
Specific association of human telomerase activity with immortal cells and cancer.
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
13
TERRA RNA Antagonizes ATRX and Protects Telomeres.
Hsueh-Ping Chu, Catherine Cifuentes-Rojas, Barry Kesner, Eric Aeby, Hun-Goo Lee, Chunyao Wei, Hyun Jung Oh, Myriam Boukhali, Wilhelm Haas, Jeannie T Lee. Cell 2017
Hsueh-Ping Chu, Catherine Cifuentes-Rojas, Barry Kesner, Eric Aeby, Hun-Goo Lee, Chunyao Wei, Hyun Jung Oh, Myriam Boukhali, Wilhelm Haas, Jeannie T Lee. Cell 2017
13
Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II.
Stefan Schoeftner, Maria A Blasco. Nat Cell Biol 2008
Stefan Schoeftner, Maria A Blasco. Nat Cell Biol 2008
13
TERRA RNA binding to TRF2 facilitates heterochromatin formation and ORC recruitment at telomeres.
Zhong Deng, Julie Norseen, Andreas Wiedmer, Harold Riethman, Paul M Lieberman. Mol Cell 2009
Zhong Deng, Julie Norseen, Andreas Wiedmer, Harold Riethman, Paul M Lieberman. Mol Cell 2009
13
13
Shelterin: the protein complex that shapes and safeguards human telomeres.
Titia de Lange. Genes Dev 2005
Titia de Lange. Genes Dev 2005
13
FANCM, BRCA1, and BLM cooperatively resolve the replication stress at the ALT telomeres.
Xiaolei Pan, William C Drosopoulos, Louisa Sethi, Advaitha Madireddy, Carl L Schildkraut, Dong Zhang. Proc Natl Acad Sci U S A 2017
Xiaolei Pan, William C Drosopoulos, Louisa Sethi, Advaitha Madireddy, Carl L Schildkraut, Dong Zhang. Proc Natl Acad Sci U S A 2017
27
Distinct factors control histone variant H3.3 localization at specific genomic regions.
Aaron D Goldberg, Laura A Banaszynski, Kyung-Min Noh, Peter W Lewis, Simon J Elsaesser, Sonja Stadler, Scott Dewell, Martin Law, Xingyi Guo, Xuan Li,[...]. Cell 2010
Aaron D Goldberg, Laura A Banaszynski, Kyung-Min Noh, Peter W Lewis, Simon J Elsaesser, Sonja Stadler, Scott Dewell, Martin Law, Xingyi Guo, Xuan Li,[...]. Cell 2010
12
Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres.
Peter W Lewis, Simon J Elsaesser, Kyung-Min Noh, Sonja C Stadler, C David Allis. Proc Natl Acad Sci U S A 2010
Peter W Lewis, Simon J Elsaesser, Kyung-Min Noh, Sonja C Stadler, C David Allis. Proc Natl Acad Sci U S A 2010
12
Telomeric RNA-DNA hybrids affect telomere-length dynamics and senescence.
Bettina Balk, André Maicher, Martina Dees, Julia Klermund, Sarah Luke-Glaser, Katharina Bender, Brian Luke. Nat Struct Mol Biol 2013
Bettina Balk, André Maicher, Martina Dees, Julia Klermund, Sarah Luke-Glaser, Katharina Bender, Brian Luke. Nat Struct Mol Biol 2013
12
Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.
Eros Lazzerini Denchi, Titia de Lange. Nature 2007
Eros Lazzerini Denchi, Titia de Lange. Nature 2007
12
12
The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins.
Patrick Ryan Potts, Hongtao Yu. Nat Struct Mol Biol 2007
Patrick Ryan Potts, Hongtao Yu. Nat Struct Mol Biol 2007
12
The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT).
Robert Lu, Julienne J O'Rourke, Alexander P Sobinoff, Joshua A M Allen, Christopher B Nelson, Christopher G Tomlinson, Michael Lee, Roger R Reddel, Andrew J Deans, Hilda A Pickett. Nat Commun 2019
Robert Lu, Julienne J O'Rourke, Alexander P Sobinoff, Joshua A M Allen, Christopher B Nelson, Christopher G Tomlinson, Michael Lee, Roger R Reddel, Andrew J Deans, Hilda A Pickett. Nat Commun 2019
30
Selective killing of ATM- or p53-deficient cancer cells through inhibition of ATR.
Philip M Reaper, Matthew R Griffiths, Joanna M Long, Jean-Damien Charrier, Somhairle Maccormick, Peter A Charlton, Julian M C Golec, John R Pollard. Nat Chem Biol 2011
Philip M Reaper, Matthew R Griffiths, Joanna M Long, Jean-Damien Charrier, Somhairle Maccormick, Peter A Charlton, Julian M C Golec, John R Pollard. Nat Chem Biol 2011
11
SMARCAL1 Resolves Replication Stress at ALT Telomeres.
Kelli E Cox, Alexandre Maréchal, Rachel Litman Flynn. Cell Rep 2016
Kelli E Cox, Alexandre Maréchal, Rachel Litman Flynn. Cell Rep 2016
23
FANCM limits ALT activity by restricting telomeric replication stress induced by deregulated BLM and R-loops.
Bruno Silva, Richard Pentz, Ana Margarida Figueira, Rajika Arora, Yong Woo Lee, Charlotte Hodson, Harry Wischnewski, Andrew J Deans, Claus M Azzalin. Nat Commun 2019
Bruno Silva, Richard Pentz, Ana Margarida Figueira, Rajika Arora, Yong Woo Lee, Charlotte Hodson, Harry Wischnewski, Andrew J Deans, Claus M Azzalin. Nat Commun 2019
29
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.