Alicia M Pickrell, Richard J Youle. Neuron 2015
Times Cited: 1109
Times Cited: 1109
Times Cited
Times Co-cited
Similarity
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy.
Michael Lazarou, Danielle A Sliter, Lesley A Kane, Shireen A Sarraf, Chunxin Wang, Jonathon L Burman, Dionisia P Sideris, Adam I Fogel, Richard J Youle. Nature 2015
Michael Lazarou, Danielle A Sliter, Lesley A Kane, Shireen A Sarraf, Chunxin Wang, Jonathon L Burman, Dionisia P Sideris, Adam I Fogel, Richard J Youle. Nature 2015
20
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism.
T Kitada, S Asakawa, N Hattori, H Matsumine, Y Yamamura, S Minoshima, M Yokochi, Y Mizuno, N Shimizu. Nature 1998
T Kitada, S Asakawa, N Hattori, H Matsumine, Y Yamamura, S Minoshima, M Yokochi, Y Mizuno, N Shimizu. Nature 1998
18
Hereditary early-onset Parkinson's disease caused by mutations in PINK1.
Enza Maria Valente, Patrick M Abou-Sleiman, Viviana Caputo, Miratul M K Muqit, Kirsten Harvey, Suzana Gispert, Zeeshan Ali, Domenico Del Turco, Anna Rita Bentivoglio, Daniel G Healy,[...]. Science 2004
Enza Maria Valente, Patrick M Abou-Sleiman, Viviana Caputo, Miratul M K Muqit, Kirsten Harvey, Suzana Gispert, Zeeshan Ali, Domenico Del Turco, Anna Rita Bentivoglio, Daniel G Healy,[...]. Science 2004
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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy.
Derek Narendra, Atsushi Tanaka, Der-Fen Suen, Richard J Youle. J Cell Biol 2008
Derek Narendra, Atsushi Tanaka, Der-Fen Suen, Richard J Youle. J Cell Biol 2008
16
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin.
Derek P Narendra, Seok Min Jin, Atsushi Tanaka, Der-Fen Suen, Clement A Gautier, Jie Shen, Mark R Cookson, Richard J Youle. PLoS Biol 2010
Derek P Narendra, Seok Min Jin, Atsushi Tanaka, Der-Fen Suen, Clement A Gautier, Jie Shen, Mark R Cookson, Richard J Youle. PLoS Biol 2010
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13
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.
Evandro F Fang, Yujun Hou, Konstantinos Palikaras, Bryan A Adriaanse, Jesse S Kerr, Beimeng Yang, Sofie Lautrup, Md Mahdi Hasan-Olive, Domenica Caponio, Xiuli Dan,[...]. Nat Neurosci 2019
Evandro F Fang, Yujun Hou, Konstantinos Palikaras, Bryan A Adriaanse, Jesse S Kerr, Beimeng Yang, Sofie Lautrup, Md Mahdi Hasan-Olive, Domenica Caponio, Xiuli Dan,[...]. Nat Neurosci 2019
13
Ubiquitin is phosphorylated by PINK1 to activate parkin.
Fumika Koyano, Kei Okatsu, Hidetaka Kosako, Yasushi Tamura, Etsu Go, Mayumi Kimura, Yoko Kimura, Hikaru Tsuchiya, Hidehito Yoshihara, Takatsugu Hirokawa,[...]. Nature 2014
Fumika Koyano, Kei Okatsu, Hidetaka Kosako, Yasushi Tamura, Etsu Go, Mayumi Kimura, Yoko Kimura, Hikaru Tsuchiya, Hidehito Yoshihara, Takatsugu Hirokawa,[...]. Nature 2014
12
Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells.
Lei Liu, Du Feng, Guo Chen, Ming Chen, Qiaoxia Zheng, Pingping Song, Qi Ma, Chongzhuo Zhu, Rui Wang, Wanjun Qi,[...]. Nat Cell Biol 2012
Lei Liu, Du Feng, Guo Chen, Ming Chen, Qiaoxia Zheng, Pingping Song, Qi Ma, Chongzhuo Zhu, Rui Wang, Wanjun Qi,[...]. Nat Cell Biol 2012
12
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy.
Noriyuki Matsuda, Shigeto Sato, Kahori Shiba, Kei Okatsu, Keiko Saisho, Clement A Gautier, Yu-Shin Sou, Shinji Saiki, Sumihiro Kawajiri, Fumiaki Sato,[...]. J Cell Biol 2010
Noriyuki Matsuda, Shigeto Sato, Kahori Shiba, Kei Okatsu, Keiko Saisho, Clement A Gautier, Yu-Shin Sou, Shinji Saiki, Sumihiro Kawajiri, Fumiaki Sato,[...]. J Cell Biol 2010
12
Parkin and PINK1 mitigate STING-induced inflammation.
Danielle A Sliter, Jennifer Martinez, Ling Hao, Xi Chen, Nuo Sun, Tara D Fischer, Jonathon L Burman, Yan Li, Zhe Zhang, Derek P Narendra,[...]. Nature 2018
Danielle A Sliter, Jennifer Martinez, Ling Hao, Xi Chen, Nuo Sun, Tara D Fischer, Jonathon L Burman, Yan Li, Zhe Zhang, Derek P Narendra,[...]. Nature 2018
11
Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
Shireen A Sarraf, Malavika Raman, Virginia Guarani-Pereira, Mathew E Sowa, Edward L Huttlin, Steven P Gygi, J Wade Harper. Nature 2013
Shireen A Sarraf, Malavika Raman, Virginia Guarani-Pereira, Mathew E Sowa, Edward L Huttlin, Steven P Gygi, J Wade Harper. Nature 2013
11
The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy.
Baris Bingol, Joy S Tea, Lilian Phu, Mike Reichelt, Corey E Bakalarski, Qinghua Song, Oded Foreman, Donald S Kirkpatrick, Morgan Sheng. Nature 2014
Baris Bingol, Joy S Tea, Lilian Phu, Mike Reichelt, Corey E Bakalarski, Qinghua Song, Oded Foreman, Donald S Kirkpatrick, Morgan Sheng. Nature 2014
11
PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility.
Xinnan Wang, Dominic Winter, Ghazaleh Ashrafi, Julia Schlehe, Yao Liang Wong, Dennis Selkoe, Sarah Rice, Judith Steen, Matthew J LaVoie, Thomas L Schwarz. Cell 2011
Xinnan Wang, Dominic Winter, Ghazaleh Ashrafi, Julia Schlehe, Yao Liang Wong, Dennis Selkoe, Sarah Rice, Judith Steen, Matthew J LaVoie, Thomas L Schwarz. Cell 2011
11
Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells.
Charleen T Chu, Jing Ji, Ruben K Dagda, Jian Fei Jiang, Yulia Y Tyurina, Alexandr A Kapralov, Vladimir A Tyurin, Naveena Yanamala, Indira H Shrivastava, Dariush Mohammadyani,[...]. Nat Cell Biol 2013
Charleen T Chu, Jing Ji, Ruben K Dagda, Jian Fei Jiang, Yulia Y Tyurina, Alexandr A Kapralov, Vladimir A Tyurin, Naveena Yanamala, Indira H Shrivastava, Dariush Mohammadyani,[...]. Nat Cell Biol 2013
10
Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance.
Sarah Pickles, Pierre Vigié, Richard J Youle. Curr Biol 2018
Sarah Pickles, Pierre Vigié, Richard J Youle. Curr Biol 2018
10
PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria.
Kei Okatsu, Toshihiko Oka, Masahiro Iguchi, Kenji Imamura, Hidetaka Kosako, Naoki Tani, Mayumi Kimura, Etsu Go, Fumika Koyano, Manabu Funayama,[...]. Nat Commun 2012
Kei Okatsu, Toshihiko Oka, Masahiro Iguchi, Kenji Imamura, Hidetaka Kosako, Naoki Tani, Mayumi Kimura, Etsu Go, Fumika Koyano, Manabu Funayama,[...]. Nat Commun 2012
10
Mitochondrial fission, fusion, and stress.
Richard J Youle, Alexander M van der Bliek. Science 2012
Richard J Youle, Alexander M van der Bliek. Science 2012
10
A regulatory signaling loop comprising the PGAM5 phosphatase and CK2 controls receptor-mediated mitophagy.
Guo Chen, Zhe Han, Du Feng, Yanfang Chen, Linbo Chen, Hao Wu, Li Huang, Changqian Zhou, Xiangyu Cai, Changying Fu,[...]. Mol Cell 2014
Guo Chen, Zhe Han, Du Feng, Yanfang Chen, Linbo Chen, Hao Wu, Li Huang, Changqian Zhou, Xiangyu Cai, Changying Fu,[...]. Mol Cell 2014
9
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65.
Chandana Kondapalli, Agne Kazlauskaite, Ning Zhang, Helen I Woodroof, David G Campbell, Robert Gourlay, Lynn Burchell, Helen Walden, Thomas J Macartney, Maria Deak,[...]. Open Biol 2012
Chandana Kondapalli, Agne Kazlauskaite, Ning Zhang, Helen I Woodroof, David G Campbell, Robert Gourlay, Lynn Burchell, Helen Walden, Thomas J Macartney, Maria Deak,[...]. Open Biol 2012
9
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1.
Sven Geisler, Kira M Holmström, Diana Skujat, Fabienne C Fiesel, Oliver C Rothfuss, Philipp J Kahle, Wolfdieter Springer. Nat Cell Biol 2010
Sven Geisler, Kira M Holmström, Diana Skujat, Fabienne C Fiesel, Oliver C Rothfuss, Philipp J Kahle, Wolfdieter Springer. Nat Cell Biol 2010
9
PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity.
Lesley A Kane, Michael Lazarou, Adam I Fogel, Yan Li, Koji Yamano, Shireen A Sarraf, Soojay Banerjee, Richard J Youle. J Cell Biol 2014
Lesley A Kane, Michael Lazarou, Adam I Fogel, Yan Li, Koji Yamano, Shireen A Sarraf, Soojay Banerjee, Richard J Youle. J Cell Biol 2014
9
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL.
Seok Min Jin, Michael Lazarou, Chunxin Wang, Lesley A Kane, Derek P Narendra, Richard J Youle. J Cell Biol 2010
Seok Min Jin, Michael Lazarou, Chunxin Wang, Lesley A Kane, Derek P Narendra, Richard J Youle. J Cell Biol 2010
9
Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis.
Alban Ordureau, Shireen A Sarraf, David M Duda, Jin-Mi Heo, Mark P Jedrychowski, Vladislav O Sviderskiy, Jennifer L Olszewski, James T Koerber, Tiao Xie, Sean A Beausoleil,[...]. Mol Cell 2014
Alban Ordureau, Shireen A Sarraf, David M Duda, Jin-Mi Heo, Mark P Jedrychowski, Vladislav O Sviderskiy, Jennifer L Olszewski, James T Koerber, Tiao Xie, Sean A Beausoleil,[...]. Mol Cell 2014
9
Parkinson disease.
Werner Poewe, Klaus Seppi, Caroline M Tanner, Glenda M Halliday, Patrik Brundin, Jens Volkmann, Anette-Eleonore Schrag, Anthony E Lang. Nat Rev Dis Primers 2017
Werner Poewe, Klaus Seppi, Caroline M Tanner, Glenda M Halliday, Patrik Brundin, Jens Volkmann, Anette-Eleonore Schrag, Anthony E Lang. Nat Rev Dis Primers 2017
9
Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy.
Nickie C Chan, Anna M Salazar, Anh H Pham, Michael J Sweredoski, Natalie J Kolawa, Robert L J Graham, Sonja Hess, David C Chan. Hum Mol Genet 2011
Nickie C Chan, Anna M Salazar, Anh H Pham, Michael J Sweredoski, Natalie J Kolawa, Robert L J Graham, Sonja Hess, David C Chan. Hum Mol Genet 2011
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Mechanism and medical implications of mammalian autophagy.
Ivan Dikic, Zvulun Elazar. Nat Rev Mol Cell Biol 2018
Ivan Dikic, Zvulun Elazar. Nat Rev Mol Cell Biol 2018
9
Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin.
Michael Lazarou, Seok Min Jin, Lesley A Kane, Richard J Youle. Dev Cell 2012
Michael Lazarou, Seok Min Jin, Lesley A Kane, Richard J Youle. Dev Cell 2012
9
Mechanism of parkin activation by PINK1.
Christina Gladkova, Sarah L Maslen, J Mark Skehel, David Komander. Nature 2018
Christina Gladkova, Sarah L Maslen, J Mark Skehel, David Komander. Nature 2018
9
Mechanism of phospho-ubiquitin-induced PARKIN activation.
Tobias Wauer, Michal Simicek, Alexander Schubert, David Komander. Nature 2015
Tobias Wauer, Michal Simicek, Alexander Schubert, David Komander. Nature 2015
8
The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy.
Jin-Mi Heo, Alban Ordureau, Joao A Paulo, Jesse Rinehart, J Wade Harper. Mol Cell 2015
Jin-Mi Heo, Alban Ordureau, Joao A Paulo, Jesse Rinehart, J Wade Harper. Mol Cell 2015
8
PINK1-induced mitophagy promotes neuroprotection in Huntington's disease.
B Khalil, N El Fissi, A Aouane, M-J Cabirol-Pol, T Rival, J-C Liévens. Cell Death Dis 2015
B Khalil, N El Fissi, A Aouane, M-J Cabirol-Pol, T Rival, J-C Liévens. Cell Death Dis 2015
8
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin.
Ira E Clark, Mark W Dodson, Changan Jiang, Joseph H Cao, Jun R Huh, Jae Hong Seol, Soon Ji Yoo, Bruce A Hay, Ming Guo. Nature 2006
Ira E Clark, Mark W Dodson, Changan Jiang, Joseph H Cao, Jun R Huh, Jae Hong Seol, Soon Ji Yoo, Bruce A Hay, Ming Guo. Nature 2006
8
Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson's disease.
Lena F Burbulla, Pingping Song, Joseph R Mazzulli, Enrico Zampese, Yvette C Wong, Sohee Jeon, David P Santos, Judith Blanz, Carolin D Obermaier, Chelsee Strojny,[...]. Science 2017
Lena F Burbulla, Pingping Song, Joseph R Mazzulli, Enrico Zampese, Yvette C Wong, Sohee Jeon, David P Santos, Judith Blanz, Carolin D Obermaier, Chelsee Strojny,[...]. Science 2017
8
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease.
M H Polymeropoulos, C Lavedan, E Leroy, S E Ide, A Dehejia, A Dutra, B Pike, H Root, J Rubenstein, R Boyer,[...]. Science 1997
M H Polymeropoulos, C Lavedan, E Leroy, S E Ide, A Dehejia, A Dutra, B Pike, H Root, J Rubenstein, R Boyer,[...]. Science 1997
8
Nix is a selective autophagy receptor for mitochondrial clearance.
Ivana Novak, Vladimir Kirkin, David G McEwan, Ji Zhang, Philipp Wild, Alexis Rozenknop, Vladimir Rogov, Frank Löhr, Doris Popovic, Angelo Occhipinti,[...]. EMBO Rep 2010
Ivana Novak, Vladimir Kirkin, David G McEwan, Ji Zhang, Philipp Wild, Alexis Rozenknop, Vladimir Rogov, Frank Löhr, Doris Popovic, Angelo Occhipinti,[...]. EMBO Rep 2010
7
AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1.
F Strappazzon, F Nazio, M Corrado, V Cianfanelli, A Romagnoli, G M Fimia, S Campello, R Nardacci, M Piacentini, M Campanella,[...]. Cell Death Differ 2015
F Strappazzon, F Nazio, M Corrado, V Cianfanelli, A Romagnoli, G M Fimia, S Campello, R Nardacci, M Piacentini, M Campanella,[...]. Cell Death Differ 2015
7
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy.
Gilad Twig, Alvaro Elorza, Anthony J A Molina, Hibo Mohamed, Jakob D Wikstrom, Gil Walzer, Linsey Stiles, Sarah E Haigh, Steve Katz, Guy Las,[...]. EMBO J 2008
Gilad Twig, Alvaro Elorza, Anthony J A Molina, Hibo Mohamed, Jakob D Wikstrom, Gil Walzer, Linsey Stiles, Sarah E Haigh, Steve Katz, Guy Las,[...]. EMBO J 2008
7
Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria.
Benjamin Richter, Danielle A Sliter, Lina Herhaus, Alexandra Stolz, Chunxin Wang, Petra Beli, Gabriele Zaffagnini, Philipp Wild, Sascha Martens, Sebastian A Wagner,[...]. Proc Natl Acad Sci U S A 2016
Benjamin Richter, Danielle A Sliter, Lina Herhaus, Alexandra Stolz, Chunxin Wang, Petra Beli, Gabriele Zaffagnini, Philipp Wild, Sascha Martens, Sebastian A Wagner,[...]. Proc Natl Acad Sci U S A 2016
7
Mitophagy and Alzheimer's Disease: Cellular and Molecular Mechanisms.
Jesse S Kerr, Bryan A Adriaanse, Nigel H Greig, Mark P Mattson, M Zameel Cader, Vilhelm A Bohr, Evandro F Fang. Trends Neurosci 2017
Jesse S Kerr, Bryan A Adriaanse, Nigel H Greig, Mark P Mattson, M Zameel Cader, Vilhelm A Bohr, Evandro F Fang. Trends Neurosci 2017
7
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.
Cristofol Vives-Bauza, Chun Zhou, Yong Huang, Mei Cui, Rosa L A de Vries, Jiho Kim, Jessica May, Maja Aleksandra Tocilescu, Wencheng Liu, Han Seok Ko,[...]. Proc Natl Acad Sci U S A 2010
Cristofol Vives-Bauza, Chun Zhou, Yong Huang, Mei Cui, Rosa L A de Vries, Jiho Kim, Jessica May, Maja Aleksandra Tocilescu, Wencheng Liu, Han Seok Ko,[...]. Proc Natl Acad Sci U S A 2010
7
7
Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment.
Andrew W Greene, Karl Grenier, Miguel A Aguileta, Stephanie Muise, Rasoul Farazifard, M Emdadul Haque, Heidi M McBride, David S Park, Edward A Fon. EMBO Rep 2012
Andrew W Greene, Karl Grenier, Miguel A Aguileta, Stephanie Muise, Rasoul Farazifard, M Emdadul Haque, Heidi M McBride, David S Park, Edward A Fon. EMBO Rep 2012
7
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases.
Michael T Lin, M Flint Beal. Nature 2006
Michael T Lin, M Flint Beal. Nature 2006
7
Mechanisms of mitophagy in cellular homeostasis, physiology and pathology.
Konstantinos Palikaras, Eirini Lionaki, Nektarios Tavernarakis. Nat Cell Biol 2018
Konstantinos Palikaras, Eirini Lionaki, Nektarios Tavernarakis. Nat Cell Biol 2018
7
Autophagy in Parkinson's Disease.
Xu Hou, Jens O Watzlawik, Fabienne C Fiesel, Wolfdieter Springer. J Mol Biol 2020
Xu Hou, Jens O Watzlawik, Fabienne C Fiesel, Wolfdieter Springer. J Mol Biol 2020
9
Functional Impairment in Miro Degradation and Mitophagy Is a Shared Feature in Familial and Sporadic Parkinson's Disease.
Chung-Han Hsieh, Atossa Shaltouki, Ashley E Gonzalez, Alexandre Bettencourt da Cruz, Lena F Burbulla, Erica St Lawrence, Birgitt Schüle, Dimitri Krainc, Theo D Palmer, Xinnan Wang. Cell Stem Cell 2016
Chung-Han Hsieh, Atossa Shaltouki, Ashley E Gonzalez, Alexandre Bettencourt da Cruz, Lena F Burbulla, Erica St Lawrence, Birgitt Schüle, Dimitri Krainc, Theo D Palmer, Xinnan Wang. Cell Stem Cell 2016
7
A neo-substrate that amplifies catalytic activity of parkinson's-disease-related kinase PINK1.
Nicholas T Hertz, Amandine Berthet, Martin L Sos, Kurt S Thorn, Al L Burlingame, Ken Nakamura, Kevan M Shokat. Cell 2013
Nicholas T Hertz, Amandine Berthet, Martin L Sos, Kurt S Thorn, Al L Burlingame, Ken Nakamura, Kevan M Shokat. Cell 2013
7
Intestinal infection triggers Parkinson's disease-like symptoms in Pink1-/- mice.
Diana Matheoud, Tyler Cannon, Aurore Voisin, Anna-Maija Penttinen, Lauriane Ramet, Ahmed M Fahmy, Charles Ducrot, Annie Laplante, Marie-Josée Bourque, Lei Zhu,[...]. Nature 2019
Diana Matheoud, Tyler Cannon, Aurore Voisin, Anna-Maija Penttinen, Lauriane Ramet, Ahmed M Fahmy, Charles Ducrot, Annie Laplante, Marie-Josée Bourque, Lei Zhu,[...]. Nature 2019
7
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.