Raquel Cabezón, E Antonio Carrera-Silva, Georgina Flórez-Grau, Andrea E Errasti, Elisabeth Calderón-Gómez, Juan José Lozano, Carolina España, Elena Ricart, Julián Panés, Carla Vanina Rothlin, Daniel Benítez-Ribas. J Leukoc Biol 2015
Times Cited: 61
Times Cited: 61
Times Cited
Times Co-cited
Similarity
TAM receptors are pleiotropic inhibitors of the innate immune response.
Carla V Rothlin, Sourav Ghosh, Elina I Zuniga, Michael B A Oldstone, Greg Lemke. Cell 2007
Carla V Rothlin, Sourav Ghosh, Elina I Zuniga, Michael B A Oldstone, Greg Lemke. Cell 2007
37
The TAM family: phosphatidylserine sensing receptor tyrosine kinases gone awry in cancer.
Douglas K Graham, Deborah DeRyckere, Kurtis D Davies, H Shelton Earp. Nat Rev Cancer 2014
Douglas K Graham, Deborah DeRyckere, Kurtis D Davies, H Shelton Earp. Nat Rev Cancer 2014
37
T cell-derived protein S engages TAM receptor signaling in dendritic cells to control the magnitude of the immune response.
Eugenio A Carrera Silva, Pamela Y Chan, Leonel Joannas, Andrea E Errasti, Nicola Gagliani, Lidia Bosurgi, Maurice Jabbour, Anthony Perry, Faye Smith-Chakmakova, Daniel Mucida,[...]. Immunity 2013
Eugenio A Carrera Silva, Pamela Y Chan, Leonel Joannas, Andrea E Errasti, Nicola Gagliani, Lidia Bosurgi, Maurice Jabbour, Anthony Perry, Faye Smith-Chakmakova, Daniel Mucida,[...]. Immunity 2013
36
Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family.
Q Lu, G Lemke. Science 2001
Q Lu, G Lemke. Science 2001
32
MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis.
Rebecca S Cook, Kristen M Jacobsen, Anne M Wofford, Deborah DeRyckere, Jamie Stanford, Anne L Prieto, Elizabeth Redente, Melissa Sandahl, Debra M Hunter, Karen E Strunk,[...]. J Clin Invest 2013
Rebecca S Cook, Kristen M Jacobsen, Anne M Wofford, Deborah DeRyckere, Jamie Stanford, Anne L Prieto, Elizabeth Redente, Melissa Sandahl, Debra M Hunter, Karen E Strunk,[...]. J Clin Invest 2013
31
Diversification of TAM receptor tyrosine kinase function.
Anna Zagórska, Paqui G Través, Erin D Lew, Ian Dransfield, Greg Lemke. Nat Immunol 2014
Anna Zagórska, Paqui G Través, Erin D Lew, Ian Dransfield, Greg Lemke. Nat Immunol 2014
29
Receptor tyrosine kinases, TYRO3, AXL, and MER, demonstrate distinct patterns and complex regulation of ligand-induced activation.
Wen-I Tsou, Khanh-Quynh N Nguyen, Daniel A Calarese, Scott J Garforth, Anita L Antes, Sergey V Smirnov, Steve C Almo, Raymond B Birge, Sergei V Kotenko. J Biol Chem 2014
Wen-I Tsou, Khanh-Quynh N Nguyen, Daniel A Calarese, Scott J Garforth, Anita L Antes, Sergey V Smirnov, Steve C Almo, Raymond B Birge, Sergei V Kotenko. J Biol Chem 2014
29
Phagocytosis and clearance of apoptotic cells is mediated by MER.
R S Scott, E J McMahon, S M Pop, E A Reap, R Caricchio, P L Cohen, H S Earp, G K Matsushima. Nature 2001
R S Scott, E J McMahon, S M Pop, E A Reap, R Caricchio, P L Cohen, H S Earp, G K Matsushima. Nature 2001
29
TAM receptor signaling in immune homeostasis.
Carla V Rothlin, Eugenio A Carrera-Silva, Lidia Bosurgi, Sourav Ghosh. Annu Rev Immunol 2015
Carla V Rothlin, Eugenio A Carrera-Silva, Lidia Bosurgi, Sourav Ghosh. Annu Rev Immunol 2015
27
The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells.
Magdalena Paolino, Axel Choidas, Stephanie Wallner, Blanka Pranjic, Iris Uribesalgo, Stefanie Loeser, Amanda M Jamieson, Wallace Y Langdon, Fumiyo Ikeda, Juan Pablo Fededa,[...]. Nature 2014
Magdalena Paolino, Axel Choidas, Stephanie Wallner, Blanka Pranjic, Iris Uribesalgo, Stefanie Loeser, Amanda M Jamieson, Wallace Y Langdon, Fumiyo Ikeda, Juan Pablo Fededa,[...]. Nature 2014
27
Macrophages and dendritic cells use different Axl/Mertk/Tyro3 receptors in clearance of apoptotic cells.
Heather M Seitz, Todd D Camenisch, Greg Lemke, H Shelton Earp, Glenn K Matsushima. J Immunol 2007
Heather M Seitz, Todd D Camenisch, Greg Lemke, H Shelton Earp, Glenn K Matsushima. J Immunol 2007
26
MERTK Acts as a Costimulatory Receptor on Human CD8+ T Cells.
Marlies J W Peeters, Donata Dulkeviciute, Arianna Draghi, Cathrin Ritter, Anne Rahbech, Signe K Skadborg, Tina Seremet, Ana Micaela Carnaz Simões, Evelina Martinenaite, Hólmfridur R Halldórsdóttir,[...]. Cancer Immunol Res 2019
Marlies J W Peeters, Donata Dulkeviciute, Arianna Draghi, Cathrin Ritter, Anne Rahbech, Signe K Skadborg, Tina Seremet, Ana Micaela Carnaz Simões, Evelina Martinenaite, Hólmfridur R Halldórsdóttir,[...]. Cancer Immunol Res 2019
64
Efficient clearance of early apoptotic cells by human macrophages requires M2c polarization and MerTK induction.
Gaetano Zizzo, Brendan A Hilliard, Marc Monestier, Philip L Cohen. J Immunol 2012
Gaetano Zizzo, Brendan A Hilliard, Marc Monestier, Philip L Cohen. J Immunol 2012
24
The mer receptor tyrosine kinase: expression and function suggest a role in innate immunity.
Edward M Behrens, Paul Gadue, Shun-you Gong, Stacey Garrett, Paul L Stein, Philip L Cohen. Eur J Immunol 2003
Edward M Behrens, Paul Gadue, Shun-you Gong, Stacey Garrett, Paul L Stein, Philip L Cohen. Eur J Immunol 2003
22
A novel receptor tyrosine kinase, Mer, inhibits TNF-alpha production and lipopolysaccharide-induced endotoxic shock.
T D Camenisch, B H Koller, H S Earp, G K Matsushima. J Immunol 1999
T D Camenisch, B H Koller, H S Earp, G K Matsushima. J Immunol 1999
21
The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases.
T N Stitt, G Conn, M Gore, C Lai, J Bruno, C Radziejewski, K Mattsson, J Fisher, D R Gies, P F Jones. Cell 1995
T N Stitt, G Conn, M Gore, C Lai, J Bruno, C Radziejewski, K Mattsson, J Fisher, D R Gies, P F Jones. Cell 1995
19
TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer.
Rachel M A Linger, Amy K Keating, H Shelton Earp, Douglas K Graham. Adv Cancer Res 2008
Rachel M A Linger, Amy K Keating, H Shelton Earp, Douglas K Graham. Adv Cancer Res 2008
19
Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities.
Erin D Lew, Jennifer Oh, Patrick G Burrola, Irit Lax, Anna Zagórska, Paqui G Través, Joseph Schlessinger, Greg Lemke. Elife 2014
Erin D Lew, Jennifer Oh, Patrick G Burrola, Irit Lax, Anna Zagórska, Paqui G Través, Joseph Schlessinger, Greg Lemke. Elife 2014
19
Tyro-3 family receptors are essential regulators of mammalian spermatogenesis.
Q Lu, M Gore, Q Zhang, T Camenisch, S Boast, F Casagranda, C Lai, M K Skinner, R Klein, G K Matsushima,[...]. Nature 1999
Q Lu, M Gore, Q Zhang, T Camenisch, S Boast, F Casagranda, C Lai, M K Skinner, R Klein, G K Matsushima,[...]. Nature 1999
18
Phosphatidylserine Sensing by TAM Receptors Regulates AKT-Dependent Chemoresistance and PD-L1 Expression.
Canan Kasikara, Sushil Kumar, Stanley Kimani, Wen-I Tsou, Ke Geng, Viralkumar Davra, Ganapathy Sriram, Connor Devoe, Khanh-Quynh N Nguyen, Anita Antes,[...]. Mol Cancer Res 2017
Canan Kasikara, Sushil Kumar, Stanley Kimani, Wen-I Tsou, Ke Geng, Viralkumar Davra, Ganapathy Sriram, Connor Devoe, Khanh-Quynh N Nguyen, Anita Antes,[...]. Mol Cancer Res 2017
18
UNC2025, a MERTK Small-Molecule Inhibitor, Is Therapeutically Effective Alone and in Combination with Methotrexate in Leukemia Models.
Deborah DeRyckere, Alisa B Lee-Sherick, Madeline G Huey, Amanda A Hill, Jeffrey W Tyner, Kristen M Jacobsen, Lauren S Page, Gregory G Kirkpatrick, Fatma Eryildiz, Stephanie A Montgomery,[...]. Clin Cancer Res 2017
Deborah DeRyckere, Alisa B Lee-Sherick, Madeline G Huey, Amanda A Hill, Jeffrey W Tyner, Kristen M Jacobsen, Lauren S Page, Gregory G Kirkpatrick, Fatma Eryildiz, Stephanie A Montgomery,[...]. Clin Cancer Res 2017
28
MERTK inhibition alters the PD-1 axis and promotes anti-leukemia immunity.
Alisa B Lee-Sherick, Kristen M Jacobsen, Curtis J Henry, Madeline G Huey, Rebecca E Parker, Lauren S Page, Amanda A Hill, Xiaodong Wang, Stephen V Frye, H Shelton Earp,[...]. JCI Insight 2018
Alisa B Lee-Sherick, Kristen M Jacobsen, Curtis J Henry, Madeline G Huey, Rebecca E Parker, Lauren S Page, Amanda A Hill, Xiaodong Wang, Stephen V Frye, H Shelton Earp,[...]. JCI Insight 2018
27
Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP.
Yi Zhou, Mingjian Fei, Gu Zhang, Wei-Ching Liang, WeiYu Lin, Yan Wu, Robert Piskol, John Ridgway, Erin McNamara, Haochu Huang,[...]. Immunity 2020
Yi Zhou, Mingjian Fei, Gu Zhang, Wei-Ching Liang, WeiYu Lin, Yan Wu, Robert Piskol, John Ridgway, Erin McNamara, Haochu Huang,[...]. Immunity 2020
18
Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases.
K Nagata, K Ohashi, T Nakano, H Arita, C Zong, H Hanafusa, K Mizuno. J Biol Chem 1996
K Nagata, K Ohashi, T Nakano, H Arita, C Zong, H Hanafusa, K Mizuno. J Biol Chem 1996
16
MerTK is required for apoptotic cell-induced T cell tolerance.
Mark A Wallet, Pradip Sen, Rafael R Flores, Yaming Wang, Zuoan Yi, Yingsu Huang, Clayton E Mathews, H Shelton Earp, Glenn Matsushima, Bo Wang,[...]. J Exp Med 2008
Mark A Wallet, Pradip Sen, Rafael R Flores, Yaming Wang, Zuoan Yi, Yingsu Huang, Clayton E Mathews, H Shelton Earp, Glenn Matsushima, Bo Wang,[...]. J Exp Med 2008
16
Apoptotic cells induce Mer tyrosine kinase-dependent blockade of NF-kappaB activation in dendritic cells.
Pradip Sen, Mark A Wallet, Zuoan Yi, Yingsu Huang, Michael Henderson, Clayton E Mathews, H Shelton Earp, Glenn Matsushima, Albert S Baldwin, Roland M Tisch. Blood 2007
Pradip Sen, Mark A Wallet, Zuoan Yi, Yingsu Huang, Michael Henderson, Clayton E Mathews, H Shelton Earp, Glenn Matsushima, Albert S Baldwin, Roland M Tisch. Blood 2007
16
TAM receptors, Gas6, and protein S: roles in inflammation and hemostasis.
Jonathan H M van der Meer, Tom van der Poll, Cornelis van 't Veer. Blood 2014
Jonathan H M van der Meer, Tom van der Poll, Cornelis van 't Veer. Blood 2014
16
UNC2025, a potent and orally bioavailable MER/FLT3 dual inhibitor.
Weihe Zhang, Deborah DeRyckere, Debra Hunter, Jing Liu, Michael A Stashko, Katherine A Minson, Christopher T Cummings, Minjung Lee, Trevor G Glaros, Dianne L Newton,[...]. J Med Chem 2014
Weihe Zhang, Deborah DeRyckere, Debra Hunter, Jing Liu, Michael A Stashko, Katherine A Minson, Christopher T Cummings, Minjung Lee, Trevor G Glaros, Dianne L Newton,[...]. J Med Chem 2014
16
Targeting Tyro3, Axl and MerTK (TAM receptors): implications for macrophages in the tumor microenvironment.
Kayla V Myers, Sarah R Amend, Kenneth J Pienta. Mol Cancer 2019
Kayla V Myers, Sarah R Amend, Kenneth J Pienta. Mol Cancer 2019
16
Phase I (safety) study of autologous tolerogenic dendritic cells in type 1 diabetic patients.
Nick Giannoukakis, Brett Phillips, David Finegold, Jo Harnaha, Massimo Trucco. Diabetes Care 2011
Nick Giannoukakis, Brett Phillips, David Finegold, Jo Harnaha, Massimo Trucco. Diabetes Care 2011
14
Comparative study of clinical grade human tolerogenic dendritic cells.
M Naranjo-Gómez, D Raïch-Regué, C Oñate, L Grau-López, C Ramo-Tello, R Pujol-Borrell, E Martínez-Cáceres, Francesc E Borràs. J Transl Med 2011
M Naranjo-Gómez, D Raïch-Regué, C Oñate, L Grau-López, C Ramo-Tello, R Pujol-Borrell, E Martínez-Cáceres, Francesc E Borràs. J Transl Med 2011
14
Cloning and mRNA expression analysis of a novel human protooncogene, c-mer.
D K Graham, T L Dawson, D L Mullaney, H R Snodgrass, H S Earp. Cell Growth Differ 1994
D K Graham, T L Dawson, D L Mullaney, H R Snodgrass, H S Earp. Cell Growth Differ 1994
14
Natural killer cell differentiation driven by Tyro3 receptor tyrosine kinases.
Anouk Caraux, Qingxian Lu, Nadine Fernandez, Sylvain Riou, James P Di Santo, David H Raulet, Greg Lemke, Claude Roth. Nat Immunol 2006
Anouk Caraux, Qingxian Lu, Nadine Fernandez, Sylvain Riou, James P Di Santo, David H Raulet, Greg Lemke, Claude Roth. Nat Immunol 2006
14
Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer.
R B Birge, S Boeltz, S Kumar, J Carlson, J Wanderley, D Calianese, M Barcinski, R A Brekken, X Huang, J T Hutchins,[...]. Cell Death Differ 2016
R B Birge, S Boeltz, S Kumar, J Carlson, J Wanderley, D Calianese, M Barcinski, R A Brekken, X Huang, J T Hutchins,[...]. Cell Death Differ 2016
14
Ectopic expression of the proto-oncogene Mer in pediatric T-cell acute lymphoblastic leukemia.
Douglas K Graham, Dana B Salzberg, Joanne Kurtzberg, Susan Sather, Glenn K Matsushima, Amy K Keating, Xiayuan Liang, Mark A Lovell, Sara A Williams, Thomas L Dawson,[...]. Clin Cancer Res 2006
Douglas K Graham, Dana B Salzberg, Joanne Kurtzberg, Susan Sather, Glenn K Matsushima, Amy K Keating, Xiayuan Liang, Mark A Lovell, Sara A Williams, Thomas L Dawson,[...]. Clin Cancer Res 2006
14
The Role of TAM Family Receptors in Immune Cell Function: Implications for Cancer Therapy.
Magdalena Paolino, Josef M Penninger. Cancers (Basel) 2016
Magdalena Paolino, Josef M Penninger. Cancers (Basel) 2016
14
TAM receptor tyrosine kinases as emerging targets of innate immune checkpoint blockade for cancer therapy.
Yemsratch T Akalu, Carla V Rothlin, Sourav Ghosh. Immunol Rev 2017
Yemsratch T Akalu, Carla V Rothlin, Sourav Ghosh. Immunol Rev 2017
14
Pan-TAM Tyrosine Kinase Inhibitor BMS-777607 Enhances Anti-PD-1 mAb Efficacy in a Murine Model of Triple-Negative Breast Cancer.
Canan Kasikara, Viralkumar Davra, David Calianese, Ke Geng, Thomas E Spires, Michael Quigley, Michael Wichroski, Ganapathy Sriram, Lucia Suarez-Lopez, Michael B Yaffe,[...]. Cancer Res 2019
Canan Kasikara, Viralkumar Davra, David Calianese, Ke Geng, Thomas E Spires, Michael Quigley, Michael Wichroski, Ganapathy Sriram, Lucia Suarez-Lopez, Michael B Yaffe,[...]. Cancer Res 2019
17
TNF-alpha, IL-6, and IL-1 expression is inhibited by GAS6 in monocytes/macrophages.
Federica Alciato, Pier Paolo Sainaghi, Daniele Sola, Luigi Castello, Gian Carlo Avanzi. J Leukoc Biol 2010
Federica Alciato, Pier Paolo Sainaghi, Daniele Sola, Luigi Castello, Gian Carlo Avanzi. J Leukoc Biol 2010
13
Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy.
Anne Angelillo-Scherrer, Laurent Burnier, Nathalie Flores, Pierre Savi, Maria DeMol, Paul Schaeffer, Jean-Marc Herbert, Greg Lemke, Stephen P Goff, Glenn K Matsushima,[...]. J Clin Invest 2005
Anne Angelillo-Scherrer, Laurent Burnier, Nathalie Flores, Pierre Savi, Maria DeMol, Paul Schaeffer, Jean-Marc Herbert, Greg Lemke, Stephen P Goff, Glenn K Matsushima,[...]. J Clin Invest 2005
13
Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype-positive rheumatoid arthritis patients.
Helen Benham, Hendrik J Nel, Soi Cheng Law, Ahmed M Mehdi, Shayna Street, Nishta Ramnoruth, Helen Pahau, Bernett T Lee, Jennifer Ng, Marion E G Brunck,[...]. Sci Transl Med 2015
Helen Benham, Hendrik J Nel, Soi Cheng Law, Ahmed M Mehdi, Shayna Street, Nishta Ramnoruth, Helen Pahau, Bernett T Lee, Jennifer Ng, Marion E G Brunck,[...]. Sci Transl Med 2015
13
Paradoxical role of the proto-oncogene Axl and Mer receptor tyrosine kinases in colon cancer.
Lidia Bosurgi, Jochem H Bernink, Victor Delgado Cuevas, Nicola Gagliani, Leonel Joannas, Edward T Schmid, Carmen J Booth, Sourav Ghosh, Carla V Rothlin. Proc Natl Acad Sci U S A 2013
Lidia Bosurgi, Jochem H Bernink, Victor Delgado Cuevas, Nicola Gagliani, Leonel Joannas, Edward T Schmid, Carmen J Booth, Sourav Ghosh, Carla V Rothlin. Proc Natl Acad Sci U S A 2013
13
Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase.
Philip L Cohen, Roberto Caricchio, Valsamma Abraham, Todd D Camenisch, J Charles Jennette, Robert A S Roubey, H Shelton Earp, Glenn Matsushima, Elizabeth A Reap. J Exp Med 2002
Philip L Cohen, Roberto Caricchio, Valsamma Abraham, Todd D Camenisch, J Charles Jennette, Robert A S Roubey, H Shelton Earp, Glenn Matsushima, Elizabeth A Reap. J Exp Med 2002
13
Overexpression of MERTK receptor tyrosine kinase in epithelial cancer cells drives efferocytosis in a gain-of-function capacity.
Khanh-Quynh N Nguyen, Wen-I Tsou, Daniel A Calarese, Stanley G Kimani, Sukhwinder Singh, Shelly Hsieh, Yongzhang Liu, Bin Lu, Yi Wu, Scott J Garforth,[...]. J Biol Chem 2014
Khanh-Quynh N Nguyen, Wen-I Tsou, Daniel A Calarese, Stanley G Kimani, Sukhwinder Singh, Shelly Hsieh, Yongzhang Liu, Bin Lu, Yi Wu, Scott J Garforth,[...]. J Biol Chem 2014
13
Small-Molecule Inhibition of Axl Targets Tumor Immune Suppression and Enhances Chemotherapy in Pancreatic Cancer.
Kathleen F Ludwig, Wenting Du, Noah B Sorrelle, Katarzyna Wnuk-Lipinska, Mary Topalovski, Jason E Toombs, Victoria H Cruz, Shinichi Yabuuchi, N V Rajeshkumar, Anirban Maitra,[...]. Cancer Res 2018
Kathleen F Ludwig, Wenting Du, Noah B Sorrelle, Katarzyna Wnuk-Lipinska, Mary Topalovski, Jason E Toombs, Victoria H Cruz, Shinichi Yabuuchi, N V Rajeshkumar, Anirban Maitra,[...]. Cancer Res 2018
13
Small Molecule Inhibition of MERTK Is Efficacious in Non-Small Cell Lung Cancer Models Independent of Driver Oncogene Status.
Christopher T Cummings, Weihe Zhang, Kurtis D Davies, Gregory D Kirkpatrick, Dehui Zhang, Deborah DeRyckere, Xiaodong Wang, Stephen V Frye, H Shelton Earp, Douglas K Graham. Mol Cancer Ther 2015
Christopher T Cummings, Weihe Zhang, Kurtis D Davies, Gregory D Kirkpatrick, Dehui Zhang, Deborah DeRyckere, Xiaodong Wang, Stephen V Frye, H Shelton Earp, Douglas K Graham. Mol Cancer Ther 2015
20
Immuno-oncological Efficacy of RXDX-106, a Novel TAM (TYRO3, AXL, MER) Family Small-Molecule Kinase Inhibitor.
Yumi Yokoyama, Erin D Lew, Ruth Seelige, Elizabeth A Tindall, Colin Walsh, Patrick C Fagan, Jack Y Lee, Robin Nevarez, Joanne Oh, Kathleen D Tucker,[...]. Cancer Res 2019
Yumi Yokoyama, Erin D Lew, Ruth Seelige, Elizabeth A Tindall, Colin Walsh, Patrick C Fagan, Jack Y Lee, Robin Nevarez, Joanne Oh, Kathleen D Tucker,[...]. Cancer Res 2019
18
An extended family of protein-tyrosine kinase genes differentially expressed in the vertebrate nervous system.
C Lai, G Lemke. Neuron 1991
C Lai, G Lemke. Neuron 1991
11
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.