A citation-based method for searching scientific literature

Andrew N Lane, Teresa W-M Fan. Nucleic Acids Res 2015
Times Cited: 365







List of co-cited articles
448 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
12

An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis.
Kıvanç Birsoy, Tim Wang, Walter W Chen, Elizaveta Freinkman, Monther Abu-Remaileh, David M Sabatini. Cell 2015
653
11

Cancer Cells Tune the Signaling Pathways to Empower de Novo Synthesis of Nucleotides.
Elodie Villa, Eunus S Ali, Umakant Sahu, Issam Ben-Sahra. Cancers (Basel) 2019
84
13

Understanding the Warburg effect: the metabolic requirements of cell proliferation.
Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
10

Understanding the Intersections between Metabolism and Cancer Biology.
Matthew G Vander Heiden, Ralph J DeBerardinis. Cell 2017
978
9

Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells.
Lucas B Sullivan, Dan Y Gui, Aaron M Hosios, Lauren N Bush, Elizaveta Freinkman, Matthew G Vander Heiden. Cell 2015
573
8

Global regulation of nucleotide biosynthetic genes by c-Myc.
Yen-Chun Liu, Feng Li, Jesse Handler, Cheng Ran Lisa Huang, Yan Xiang, Nicola Neretti, John M Sedivy, Karen I Zeller, Chi V Dang. PLoS One 2008
187
8

The Emerging Hallmarks of Cancer Metabolism.
Natalya N Pavlova, Craig B Thompson. Cell Metab 2016
8

From Krebs to clinic: glutamine metabolism to cancer therapy.
Brian J Altman, Zachary E Stine, Chi V Dang. Nat Rev Cancer 2016
785
7

Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis.
Shiran Rabinovich, Lital Adler, Keren Yizhak, Alona Sarver, Alon Silberman, Shani Agron, Noa Stettner, Qin Sun, Alexander Brandis, Daniel Helbling,[...]. Nature 2015
188
7

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis.
Ralph J DeBerardinis, Anthony Mancuso, Evgueni Daikhin, Ilana Nissim, Marc Yudkoff, Suzanne Wehrli, Craig B Thompson. Proc Natl Acad Sci U S A 2007
6

Fundamentals of cancer metabolism.
Ralph J DeBerardinis, Navdeep S Chandel. Sci Adv 2016
6


Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1.
Issam Ben-Sahra, Jessica J Howell, John M Asara, Brendan D Manning. Science 2013
447
5

Cell cycle-dependent regulation of pyrimidine biosynthesis.
Frederic D Sigoillot, J Andrew Berkowski, Severine M Sigoillot, Damian H Kotsis, Hedeel I Guy. J Biol Chem 2003
48
10

Metabolic regulation of cell growth and proliferation.
Jiajun Zhu, Craig B Thompson. Nat Rev Mol Cell Biol 2019
251
5

The pentose phosphate pathway and cancer.
Krushna C Patra, Nissim Hay. Trends Biochem Sci 2014
642
5

Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive cancer.
John T Cunningham, Melissa V Moreno, Alessia Lodi, Sabrina M Ronen, Davide Ruggero. Cell 2014
138
5

mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle.
Issam Ben-Sahra, Gerta Hoxhaj, Stéphane J H Ricoult, John M Asara, Brendan D Manning. Science 2016
398
5

Potential Mechanisms Connecting Purine Metabolism and Cancer Therapy.
Jie Yin, Wenkai Ren, Xingguo Huang, Jinping Deng, Tiejun Li, Yulong Yin. Front Immunol 2018
113
5

A New View into the Regulation of Purine Metabolism: The Purinosome.
Anthony M Pedley, Stephen J Benkovic. Trends Biochem Sci 2017
200
5

A roadmap for interpreting (13)C metabolite labeling patterns from cells.
Joerg M Buescher, Maciek R Antoniewicz, Laszlo G Boros, Shawn C Burgess, Henri Brunengraber, Clary B Clish, Ralph J DeBerardinis, Olivier Feron, Christian Frezza, Bart Ghesquiere,[...]. Curr Opin Biotechnol 2015
342
5

Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia.
David B Sykes, Youmna S Kfoury, François E Mercier, Mathias J Wawer, Jason M Law, Mark K Haynes, Timothy A Lewis, Amir Schajnovitz, Esha Jain, Dongjun Lee,[...]. Cell 2016
216
5


Pyrimidine pathways in health and disease.
Monika Löffler, Lynette D Fairbanks, Elke Zameitat, Anthony M Marinaki, H Anne Simmonds. Trends Mol Med 2005
144
5

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
5

Inosine Monophosphate Dehydrogenase Dependence in a Subset of Small Cell Lung Cancers.
Fang Huang, Min Ni, Milind D Chalishazar, Kenneth E Huffman, Jiyeon Kim, Ling Cai, Xiaolei Shi, Feng Cai, Lauren G Zacharias, Abbie S Ireland,[...]. Cell Metab 2018
85
5

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2.
Michael I Love, Wolfgang Huber, Simon Anders. Genome Biol 2014
5

Glutamine and cancer: cell biology, physiology, and clinical opportunities.
Christopher T Hensley, Ajla T Wasti, Ralph J DeBerardinis. J Clin Invest 2013
687
4

Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells.
Aaron M Hosios, Vivian C Hecht, Laura V Danai, Marc O Johnson, Jeffrey C Rathmell, Matthew L Steinhauser, Scott R Manalis, Matthew G Vander Heiden. Dev Cell 2016
309
4

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress.
Heather P Harding, Yuhong Zhang, Huiquing Zeng, Isabel Novoa, Phoebe D Lu, Marcella Calfon, Navid Sadri, Chi Yun, Brian Popko, Richard Paules,[...]. Mol Cell 2003
4

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway.
Jaekyoung Son, Costas A Lyssiotis, Haoqiang Ying, Xiaoxu Wang, Sujun Hua, Matteo Ligorio, Rushika M Perera, Cristina R Ferrone, Edouard Mullarky, Ng Shyh-Chang,[...]. Nature 2013
4

The molecular determinants of de novo nucleotide biosynthesis in cancer cells.
Xuemei Tong, Fangping Zhao, Craig B Thompson. Curr Opin Genet Dev 2009
212
4

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.
Aravind Subramanian, Pablo Tamayo, Vamsi K Mootha, Sayan Mukherjee, Benjamin L Ebert, Michael A Gillette, Amanda Paulovich, Scott L Pomeroy, Todd R Golub, Eric S Lander,[...]. Proc Natl Acad Sci U S A 2005
4

Targeting Metabolism for Cancer Therapy.
Alba Luengo, Dan Y Gui, Matthew G Vander Heiden. Cell Chem Biol 2017
397
4

Glucose feeds the TCA cycle via circulating lactate.
Sheng Hui, Jonathan M Ghergurovich, Raphael J Morscher, Cholsoon Jang, Xin Teng, Wenyun Lu, Lourdes A Esparza, Tannishtha Reya, Le Zhan, Jessie Yanxiang Guo,[...]. Nature 2017
590
4

Reversible compartmentalization of de novo purine biosynthetic complexes in living cells.
Songon An, Ravindra Kumar, Erin D Sheets, Stephen J Benkovic. Science 2008
321
4

Phosphoribosyl Diphosphate (PRPP): Biosynthesis, Enzymology, Utilization, and Metabolic Significance.
Bjarne Hove-Jensen, Kasper R Andersen, Mogens Kilstrup, Jan Martinussen, Robert L Switzer, Martin Willemoës. Microbiol Mol Biol Rev 2016
73
5

Stable isotope-resolved metabolomics and applications for drug development.
Teresa W-M Fan, Pawel K Lorkiewicz, Katherine Sellers, Hunter N B Moseley, Richard M Higashi, Andrew N Lane. Pharmacol Ther 2012
122
4

Metabolomics and Isotope Tracing.
Cholsoon Jang, Li Chen, Joshua D Rabinowitz. Cell 2018
269
4

Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation.
Katherine Sellers, Matthew P Fox, Michael Bousamra, Stephen P Slone, Richard M Higashi, Donald M Miller, Yali Wang, Jun Yan, Mariia O Yuneva, Rahul Deshpande,[...]. J Clin Invest 2015
315
4

The novel dihydroorotate dehydrogenase (DHODH) inhibitor BAY 2402234 triggers differentiation and is effective in the treatment of myeloid malignancies.
Sven Christian, Claudia Merz, Laura Evans, Stefan Gradl, Henrik Seidel, Anders Friberg, Ashley Eheim, Pascale Lejeune, Krzysztof Brzezinka, Katja Zimmermann,[...]. Leukemia 2019
70
5

LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells.
Almut Brand, Katrin Singer, Gudrun E Koehl, Marlene Kolitzus, Gabriele Schoenhammer, Annette Thiel, Carina Matos, Christina Bruss, Sebastian Klobuch, Katrin Peter,[...]. Cell Metab 2016
627
4

Serine and glycine metabolism in cancer.
Ivano Amelio, Francesca Cutruzzolá, Alexey Antonov, Massimiliano Agostini, Gerry Melino. Trends Biochem Sci 2014
506
4

Trimmomatic: a flexible trimmer for Illumina sequence data.
Anthony M Bolger, Marc Lohse, Bjoern Usadel. Bioinformatics 2014
4

HTSeq--a Python framework to work with high-throughput sequencing data.
Simon Anders, Paul Theodor Pyl, Wolfgang Huber. Bioinformatics 2015
4

Glutamine Synthetase Promotes Radiation Resistance via Facilitating Nucleotide Metabolism and Subsequent DNA Damage Repair.
Shujun Fu, Zhi Li, Lanbo Xiao, Wenfeng Hu, Lu Zhang, Bowen Xie, Qin Zhou, Junju He, Yanfang Qiu, Ming Wen,[...]. Cell Rep 2019
54
7

Regulation of nucleotide metabolism by mutant p53 contributes to its gain-of-function activities.
Madhusudhan Kollareddy, Elizabeth Dimitrova, Krishna C Vallabhaneni, Adriano Chan, Thuc Le, Krishna M Chauhan, Zunamys I Carrero, Gopalakrishnan Ramakrishnan, Kounosuke Watabe, Ygal Haupt,[...]. Nat Commun 2015
82
4

The Warburg Effect: How Does it Benefit Cancer Cells?
Maria V Liberti, Jason W Locasale. Trends Biochem Sci 2016
4

Replication and ribosomal stress induced by targeting pyrimidine synthesis and cellular checkpoints suppress p53-deficient tumors.
Sona Hubackova, Eliska Davidova, Stepana Boukalova, Jaromira Kovarova, Martina Bajzikova, Ana Coelho, Mikkel G Terp, Henrik J Ditzel, Jakub Rohlena, Jiri Neuzil. Cell Death Dis 2020
13
30


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.