A citation-based method for searching scientific literature

Raphael Ceccaldi, Jessica C Liu, Ravindra Amunugama, Ildiko Hajdu, Benjamin Primack, Mark I R Petalcorin, Kevin W O'Connor, Panagiotis A Konstantinopoulos, Stephen J Elledge, Simon J Boulton, Timur Yusufzai, Alan D D'Andrea. Nature 2015
Times Cited: 423







List of co-cited articles
1654 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination.
Pedro A Mateos-Gomez, Fade Gong, Nidhi Nair, Kyle M Miller, Eros Lazzerini-Denchi, Agnel Sfeir. Nature 2015
362
57

Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks.
David W Wyatt, Wanjuan Feng, Michael P Conlin, Matthew J Yousefzadeh, Steven A Roberts, Piotr Mieczkowski, Richard D Wood, Gaorav P Gupta, Dale A Ramsden. Mol Cell 2016
137
30

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.
Hannah Farmer, Nuala McCabe, Christopher J Lord, Andrew N J Tutt, Damian A Johnson, Tobias B Richardson, Manuela Santarosa, Krystyna J Dillon, Ian Hickson, Charlotte Knights,[...]. Nature 2005
30

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase.
Helen E Bryant, Niklas Schultz, Huw D Thomas, Kayan M Parker, Dan Flower, Elena Lopez, Suzanne Kyle, Mark Meuth, Nicola J Curtin, Thomas Helleday. Nature 2005
29

Non-homologous DNA end joining and alternative pathways to double-strand break repair.
Howard H Y Chang, Nicholas R Pannunzio, Noritaka Adachi, Michael R Lieber. Nat Rev Mol Cell Biol 2017
662
27

Mechanism of suppression of chromosomal instability by DNA polymerase POLQ.
Matthew J Yousefzadeh, David W Wyatt, Kei-Ichi Takata, Yunxiang Mu, Sean C Hensley, Junya Tomida, Göran O Bylund, Sylvie Doublié, Erik Johansson, Dale A Ramsden,[...]. PLoS Genet 2014
155
26

Genetic determinants of cellular addiction to DNA polymerase theta.
Wanjuan Feng, Dennis A Simpson, Juan Carvajal-Garcia, Brandon A Price, Rashmi J Kumar, Lisle E Mose, Richard D Wood, Naim Rashid, Jeremy E Purvis, Joel S Parker,[...]. Nat Commun 2019
55
47

DNA double-strand break repair-pathway choice in somatic mammalian cells.
Ralph Scully, Arvind Panday, Rajula Elango, Nicholas A Willis. Nat Rev Mol Cell Biol 2019
382
24

Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ.
Tatiana Kent, Gurushankar Chandramouly, Shane Michael McDevitt, Ahmet Y Ozdemir, Richard T Pomerantz. Nat Struct Mol Biol 2015
175
24

53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks.
Samuel F Bunting, Elsa Callén, Nancy Wong, Hua-Tang Chen, Federica Polato, Amanda Gunn, Anne Bothmer, Niklas Feldhahn, Oscar Fernandez-Capetillo, Liu Cao,[...]. Cell 2010
23

DNA polymerase θ (POLQ), double-strand break repair, and cancer.
Richard D Wood, Sylvie Doublié. DNA Repair (Amst) 2016
111
22

The helicase domain of Polθ counteracts RPA to promote alt-NHEJ.
Pedro A Mateos-Gomez, Tatiana Kent, Sarah K Deng, Shane McDevitt, Ekaterina Kashkina, Trung M Hoang, Richard T Pomerantz, Agnel Sfeir. Nat Struct Mol Biol 2017
78
25

The shieldin complex mediates 53BP1-dependent DNA repair.
Sylvie M Noordermeer, Salomé Adam, Dheva Setiaputra, Marco Barazas, Stephen J Pettitt, Alexanda K Ling, Michele Olivieri, Alejandro Álvarez-Quilón, Nathalie Moatti, Michal Zimmermann,[...]. Nature 2018
257
20

Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11.
Katharina Schlacher, Nicole Christ, Nicolas Siaud, Akinori Egashira, Hong Wu, Maria Jasin. Cell 2011
754
19

Mechanistic basis for microhomology identification and genome scarring by polymerase theta.
Juan Carvajal-Garcia, Jang-Eun Cho, Pablo Carvajal-Garcia, Wanjuan Feng, Richard D Wood, Jeff Sekelsky, Gaorav P Gupta, Steven A Roberts, Dale A Ramsden. Proc Natl Acad Sci U S A 2020
46
41

Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells.
Lan N Truong, Yongjiang Li, Linda Z Shi, Patty Yi-Hwa Hwang, Jing He, Hailong Wang, Niema Razavian, Michael W Berns, Xiaohua Wu. Proc Natl Acad Sci U S A 2013
281
18

Repair Pathway Choices and Consequences at the Double-Strand Break.
Raphael Ceccaldi, Beatrice Rondinelli, Alan D D'Andrea. Trends Cell Biol 2016
727
18

Loss of 53BP1 causes PARP inhibitor resistance in Brca1-mutated mouse mammary tumors.
Janneke E Jaspers, Ariena Kersbergen, Ute Boon, Wendy Sol, Liesbeth van Deemter, Serge A Zander, Rinske Drost, Ellen Wientjens, Jiuping Ji, Amal Aly,[...]. Cancer Discov 2013
328
17

Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells.
Harveer Dev, Ting-Wei Will Chiang, Chloe Lescale, Inge de Krijger, Alistair G Martin, Domenic Pilger, Julia Coates, Matylda Sczaniecka-Clift, Wenming Wei, Matthias Ostermaier,[...]. Nat Cell Biol 2018
174
16

Replication fork stability confers chemoresistance in BRCA-deficient cells.
Arnab Ray Chaudhuri, Elsa Callen, Xia Ding, Ewa Gogola, Alexandra A Duarte, Ji-Eun Lee, Nancy Wong, Vanessa Lafarga, Jennifer A Calvo, Nicholas J Panzarino,[...]. Nature 2016
439
16

A first-in-class Polymerase Theta Inhibitor selectively targets Homologous-Recombination-Deficient Tumors.
Jia Zhou, Camille Gelot, Constantia Pantelidou, Adam Li, Hatice Yücel, Rachel E Davis, Anniina Färkkilä, Bose Kochupurakkal, Aleem Syed, Geoffrey I Shapiro,[...]. Nat Cancer 2021
33
48

A Polymerase Theta-dependent repair pathway suppresses extensive genomic instability at endogenous G4 DNA sites.
Wouter Koole, Robin van Schendel, Andrea E Karambelas, Jane T van Heteren, Kristy L Okihara, Marcel Tijsterman. Nat Commun 2014
139
15

A role for human homologous recombination factors in suppressing microhomology-mediated end joining.
Sara Ahrabi, Sovan Sarkar, Sophia X Pfister, Giacomo Pirovano, Geoff S Higgins, Andrew C G Porter, Timothy C Humphrey. Nucleic Acids Res 2016
53
28


REV7 counteracts DNA double-strand break resection and affects PARP inhibition.
Guotai Xu, J Ross Chapman, Inger Brandsma, Jingsong Yuan, Martin Mistrik, Peter Bouwman, Jirina Bartkova, Ewa Gogola, Daniël Warmerdam, Marco Barazas,[...]. Nature 2015
358
15

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
14

Templated Insertions: A Smoking Gun for Polymerase Theta-Mediated End Joining.
Joost Schimmel, Robin van Schendel, Johan T den Dunnen, Marcel Tijsterman. Trends Genet 2019
47
29

PARP inhibitors: Synthetic lethality in the clinic.
Christopher J Lord, Alan Ashworth. Science 2017
14

POLQ (Pol theta), a DNA polymerase and DNA-dependent ATPase in human cells.
Mineaki Seki, Federica Marini, Richard D Wood. Nucleic Acids Res 2003
133
14

Signatures of mutational processes in human cancer.
Ludmil B Alexandrov, Serena Nik-Zainal, David C Wedge, Samuel A J R Aparicio, Sam Behjati, Andrew V Biankin, Graham R Bignell, Niccolò Bolli, Ake Borg, Anne-Lise Børresen-Dale,[...]. Nature 2013
14

DNA polymerase θ (POLQ) is important for repair of DNA double-strand breaks caused by fork collapse.
Zi Wang, Yadong Song, Shibo Li, Sunil Kurian, Rong Xiang, Takuya Chiba, Xiaohua Wu. J Biol Chem 2019
42
33

Defining the mutation signatures of DNA polymerase θ in cancer genomes.
Taejoo Hwang, Shelley Reh, Yerkin Dunbayev, Yi Zhong, Yoko Takata, Jianjun Shen, Kevin M McBride, John P Murnane, Jong Bhak, Semin Lee,[...]. NAR Cancer 2020
17
82

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.
Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig,[...]. Cell 2018
200
14

Shieldin - the protector of DNA ends.
Dheva Setiaputra, Daniel Durocher. EMBO Rep 2019
109
14

Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors.
Junko Murai, Shar-yin N Huang, Benu Brata Das, Amelie Renaud, Yiping Zhang, James H Doroshow, Jiuping Ji, Shunichi Takeda, Yves Pommier. Cancer Res 2012
14

PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways.
Minli Wang, Weizhong Wu, Wenqi Wu, Bustanur Rosidi, Lihua Zhang, Huichen Wang, George Iliakis. Nucleic Acids Res 2006
537
13

Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway.
Joseph A Newman, Christopher D O Cooper, Hazel Aitkenhead, Opher Gileadi. Structure 2015
44
29

DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability.
Fanny Lemée, Valérie Bergoglio, Anne Fernandez-Vidal, Alice Machado-Silva, Marie-Jeanne Pillaire, Anne Bieth, Catherine Gentil, Lee Baker, Anne-Laure Martin, Claire Leduc,[...]. Proc Natl Acad Sci U S A 2010
109
13



Beyond PARP-POLθ as an anticancer target.
Geoff S Higgins, Simon J Boulton. Science 2018
35
37

53BP1 cooperation with the REV7-shieldin complex underpins DNA structure-specific NHEJ.
Hind Ghezraoui, Catarina Oliveira, Jordan R Becker, Kirstin Bilham, Daniela Moralli, Consuelo Anzilotti, Roman Fischer, Mukta Deobagkar-Lele, Maria Sanchiz-Calvo, Elena Fueyo-Marcos,[...]. Nature 2018
141
13

Mutational signatures of non-homologous and polymerase theta-mediated end-joining in embryonic stem cells.
Joost Schimmel, Hanneke Kool, Robin van Schendel, Marcel Tijsterman. EMBO J 2017
62
20

53BP1-RIF1-shieldin counteracts DSB resection through CST- and Polα-dependent fill-in.
Zachary Mirman, Francisca Lottersberger, Hiroyuki Takai, Tatsuya Kibe, Yi Gong, Kaori Takai, Alessandro Bianchi, Michal Zimmermann, Daniel Durocher, Titia de Lange. Nature 2018
189
13

BRCAness revisited.
Christopher J Lord, Alan Ashworth. Nat Rev Cancer 2016
664
13

The DNA damage response: making it safe to play with knives.
Alberto Ciccia, Stephen J Elledge. Mol Cell 2010
13

Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance.
Diana Zatreanu, Helen M R Robinson, Omar Alkhatib, Marie Boursier, Harry Finch, Lerin Geo, Diego Grande, Vera Grinkevich, Robert A Heald, Sophie Langdon,[...]. Nat Commun 2021
25
52

Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.
Kristen E Mengwasser, Richard O Adeyemi, Yumei Leng, Mei Yuk Choi, Connor Clairmont, Alan D D'Andrea, Stephen J Elledge. Mol Cell 2019
80
15


A small interfering RNA screen of genes involved in DNA repair identifies tumor-specific radiosensitization by POLQ knockdown.
Geoff S Higgins, Remko Prevo, Yin-Fai Lee, Thomas Helleday, Ruth J Muschel, Steve Taylor, Michio Yoshimura, Ian D Hickson, Eric J Bernhard, W Gillies McKenna. Cancer Res 2010
80
15


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.