A citation-based method for searching scientific literature

A Phillip West, William Khoury-Hanold, Matthew Staron, Michal C Tal, Cristiana M Pineda, Sabine M Lang, Megan Bestwick, Brett A Duguay, Nuno Raimundo, Donna A MacDuff, Susan M Kaech, James R Smiley, Robert E Means, Akiko Iwasaki, Gerald S Shadel. Nature 2015
Times Cited: 656







List of co-cited articles
958 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Parkin and PINK1 mitigate STING-induced inflammation.
Danielle A Sliter, Jennifer Martinez, Ling Hao, Xi Chen, Nuo Sun, Tara D Fischer, Jonathon L Burman, Yan Li, Zhe Zhang, Derek P Narendra,[...]. Nature 2018
378
24

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway.
Lijun Sun, Jiaxi Wu, Fenghe Du, Xiang Chen, Zhijian J Chen. Science 2013
22

Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production.
Michael J White, Kate McArthur, Donald Metcalf, Rachael M Lane, John C Cambier, Marco J Herold, Mark F van Delft, Sammy Bedoui, Guillaume Lessene, Matthew E Ritchie,[...]. Cell 2014
396
20

Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA.
Anthony Rongvaux, Ruaidhrí Jackson, Christian C D Harman, Tuo Li, A Phillip West, Marcel R de Zoete, Youtong Wu, Brian Yordy, Saquib A Lakhani, Chia-Yi Kuan,[...]. Cell 2014
359
18

Mitochondrial DNA in innate immune responses and inflammatory pathology.
A Phillip West, Gerald S Shadel. Nat Rev Immunol 2017
307
18

BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis.
Kate McArthur, Lachlan W Whitehead, John M Heddleston, Lucy Li, Benjamin S Padman, Viola Oorschot, Niall D Geoghegan, Stephane Chappaz, Sophia Davidson, Hui San Chin,[...]. Science 2018
235
17


Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis.
Kenichi Shimada, Timothy R Crother, Justin Karlin, Jargalsaikhan Dagvadorj, Norika Chiba, Shuang Chen, V Krishnan Ramanujan, Andrea J Wolf, Laurent Vergnes, David M Ojcius,[...]. Immunity 2012
15

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome.
Kiichi Nakahira, Jeffrey Adam Haspel, Vijay A K Rathinam, Seon-Jin Lee, Tamas Dolinay, Hilaire C Lam, Joshua A Englert, Marlene Rabinovitch, Manuela Cernadas, Hong Pyo Kim,[...]. Nat Immunol 2011
15

cGAS surveillance of micronuclei links genome instability to innate immunity.
Karen J Mackenzie, Paula Carroll, Carol-Anne Martin, Olga Murina, Adeline Fluteau, Daniel J Simpson, Nelly Olova, Hannah Sutcliffe, Jacqueline K Rainger, Andrea Leitch,[...]. Nature 2017
519
14

cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING.
Andrea Ablasser, Marion Goldeck, Taner Cavlar, Tobias Deimling, Gregor Witte, Ingo Röhl, Karl-Peter Hopfner, Janos Ludwig, Veit Hornung. Nature 2013
676
13

DNA damage primes the type I interferon system via the cytosolic DNA sensor STING to promote anti-microbial innate immunity.
Anetta Härtlova, Saskia F Erttmann, Faizal Am Raffi, Anja M Schmalz, Ulrike Resch, Sharath Anugula, Stefan Lienenklaus, Lisa M Nilsson, Andrea Kröger, Jonas A Nilsson,[...]. Immunity 2015
339
13

New mitochondrial DNA synthesis enables NLRP3 inflammasome activation.
Zhenyu Zhong, Shuang Liang, Elsa Sanchez-Lopez, Feng He, Shabnam Shalapour, Xue-Jia Lin, Jerry Wong, Siyuan Ding, Ekihiro Seki, Bernd Schnabl,[...]. Nature 2018
285
13

Mitochondrial double-stranded RNA triggers antiviral signalling in humans.
Ashish Dhir, Somdutta Dhir, Lukasz S Borowski, Laura Jimenez, Michael Teitell, Agnès Rötig, Yanick J Crow, Gillian I Rice, Darragh Duffy, Christelle Tamby,[...]. Nature 2018
162
13

DNA sensing by the cGAS-STING pathway in health and disease.
Mona Motwani, Scott Pesiridis, Katherine A Fitzgerald. Nat Rev Genet 2019
230
12

Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence.
Selene Glück, Baptiste Guey, Muhammet Fatih Gulen, Katharina Wolter, Tae-Won Kang, Niklas Arndt Schmacke, Anne Bridgeman, Jan Rehwinkel, Lars Zender, Andrea Ablasser. Nat Cell Biol 2017
341
12


Molecular mechanisms and cellular functions of cGAS-STING signalling.
Karl-Peter Hopfner, Veit Hornung. Nat Rev Mol Cell Biol 2020
95
12

VDAC oligomers form mitochondrial pores to release mtDNA fragments and promote lupus-like disease.
Jeonghan Kim, Rajeev Gupta, Luz P Blanco, Shutong Yang, Anna Shteinfer-Kuzmine, Kening Wang, Jun Zhu, Hee Eun Yoon, Xinghao Wang, Martijn Kerkhofs,[...]. Science 2019
88
12

Mitotic progression following DNA damage enables pattern recognition within micronuclei.
Shane M Harding, Joseph L Benci, Jerome Irianto, Dennis E Discher, Andy J Minn, Roger A Greenberg. Nature 2017
501
11

Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects.
Xiao-Dong Li, Jiaxi Wu, Daxing Gao, Hua Wang, Lijun Sun, Zhijian J Chen. Science 2013
555
10

Circulating mitochondrial DAMPs cause inflammatory responses to injury.
Qin Zhang, Mustafa Raoof, Yu Chen, Yuka Sumi, Tolga Sursal, Wolfgang Junger, Karim Brohi, Kiyoshi Itagaki, Carl J Hauser. Nature 2010
10


Cytoplasmic chromatin triggers inflammation in senescence and cancer.
Zhixun Dou, Kanad Ghosh, Maria Grazia Vizioli, Jiajun Zhu, Payel Sen, Kirk J Wangensteen, Johayra Simithy, Yemin Lan, Yanping Lin, Zhuo Zhou,[...]. Nature 2017
372
10

Mitochondrial DNA in inflammation and immunity.
Joel S Riley, Stephen Wg Tait. EMBO Rep 2020
85
11

Cyclic GMP-AMP synthase is activated by double-stranded DNA-induced oligomerization.
Xin Li, Chang Shu, Guanghui Yi, Catherine T Chaton, Catherine L Shelton, Jiasheng Diao, Xiaobing Zuo, C Cheng Kao, Andrew B Herr, Pingwei Li. Immunity 2013
250
9

Structural mechanism of cytosolic DNA sensing by cGAS.
Filiz Civril, Tobias Deimling, Carina C de Oliveira Mann, Andrea Ablasser, Manuela Moldt, Gregor Witte, Veit Hornung, Karl-Peter Hopfner. Nature 2013
341
9

Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing.
Qi Chen, Lijun Sun, Zhijian J Chen. Nat Immunol 2016
649
9

cGAS is essential for cellular senescence.
Hui Yang, Hanze Wang, Junyao Ren, Qi Chen, Zhijian J Chen. Proc Natl Acad Sci U S A 2017
337
9

Mitochondria are the powerhouses of immunity.
Evanna L Mills, Beth Kelly, Luke A J O'Neill. Nat Immunol 2017
331
9

Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis.
Ki Wung Chung, Poonam Dhillon, Shizheng Huang, Xin Sheng, Rojesh Shrestha, Chengxiang Qiu, Brett A Kaufman, Jihwan Park, Liming Pei, Joseph Baur,[...]. Cell Metab 2019
77
11

cGAS in action: Expanding roles in immunity and inflammation.
Andrea Ablasser, Zhijian J Chen. Science 2019
195
8

Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase.
Pu Gao, Manuel Ascano, Yang Wu, Winfried Barchet, Barbara L Gaffney, Thomas Zillinger, Artem A Serganov, Yizhou Liu, Roger A Jones, Gunther Hartmann,[...]. Cell 2013
463
8

A role for mitochondria in NLRP3 inflammasome activation.
Rongbin Zhou, Amir S Yazdi, Philippe Menu, Jürg Tschopp. Nature 2011
8

Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA.
Jiaxi Wu, Lijun Sun, Xiang Chen, Fenghe Du, Heping Shi, Chuo Chen, Zhijian J Chen. Science 2013
990
8

Nuclear cGAS suppresses DNA repair and promotes tumorigenesis.
Haipeng Liu, Haiping Zhang, Xiangyang Wu, Dapeng Ma, Juehui Wu, Lin Wang, Yan Jiang, Yiyan Fei, Chenggang Zhu, Rong Tan,[...]. Nature 2018
179
8



Chromosomal instability drives metastasis through a cytosolic DNA response.
Samuel F Bakhoum, Bryan Ngo, Ashley M Laughney, Julie-Ann Cavallo, Charles J Murphy, Peter Ly, Pragya Shah, Roshan K Sriram, Thomas B K Watkins, Neil K Taunk,[...]. Nature 2018
408
8


Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice.
N G Larsson, J Wang, H Wilhelmsson, A Oldfors, P Rustin, M Lewandoski, G S Barsh, D A Clayton. Nat Genet 1998
8

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism.
T Kitada, S Asakawa, N Hattori, H Matsumine, Y Yamamura, S Minoshima, M Yokochi, Y Mizuno, N Shimizu. Nature 1998
7

Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress.
Alicia M Pickrell, Chiu-Hui Huang, Scott R Kennedy, Alban Ordureau, Dionisia P Sideris, Jake G Hoekstra, J Wade Harper, Richard J Youle. Neuron 2015
184
7

cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders.
Liudmila Andreeva, Björn Hiller, Dirk Kostrewa, Charlotte Lässig, Carina C de Oliveira Mann, David Jan Drexler, Andreas Maiser, Moritz Gaidt, Heinrich Leonhardt, Veit Hornung,[...]. Nature 2017
154
7

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2.
Michael I Love, Wolfgang Huber, Simon Anders. Genome Biol 2014
7

The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy.
Robert O Watson, Samantha L Bell, Donna A MacDuff, Jacqueline M Kimmey, Elie J Diner, Joanna Olivas, Russell E Vance, Christina L Stallings, Herbert W Virgin, Jeffery S Cox. Cell Host Microbe 2015
319
7

Endogenously oxidized mitochondrial DNA induces in vivo and in vitro inflammatory responses.
L Vincent Collins, Shahin Hajizadeh, Elisabeth Holme, Ing-Marie Jonsson, Andrej Tarkowski. J Leukoc Biol 2004
262
7

Mitochondria in innate immune responses.
A Phillip West, Gerald S Shadel, Sankar Ghosh. Nat Rev Immunol 2011
695
7

The Roles of Mitochondrial Damage-Associated Molecular Patterns in Diseases.
Kiichi Nakahira, Shu Hisata, Augustine M K Choi. Antioxid Redox Signal 2015
116
7

Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance.
Sarah Pickles, Pierre Vigié, Richard J Youle. Curr Biol 2018
522
7


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.