A citation-based method for searching scientific literature

Tatiana Kent, Gurushankar Chandramouly, Shane Michael McDevitt, Ahmet Y Ozdemir, Richard T Pomerantz. Nat Struct Mol Biol 2015
Times Cited: 186







List of co-cited articles
1459 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination.
Pedro A Mateos-Gomez, Fade Gong, Nidhi Nair, Kyle M Miller, Eros Lazzerini-Denchi, Agnel Sfeir. Nature 2015
391
57

Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair.
Raphael Ceccaldi, Jessica C Liu, Ravindra Amunugama, Ildiko Hajdu, Benjamin Primack, Mark I R Petalcorin, Kevin W O'Connor, Panagiotis A Konstantinopoulos, Stephen J Elledge, Simon J Boulton,[...]. Nature 2015
463
56

Mechanism of suppression of chromosomal instability by DNA polymerase POLQ.
Matthew J Yousefzadeh, David W Wyatt, Kei-Ichi Takata, Yunxiang Mu, Sean C Hensley, Junya Tomida, Göran O Bylund, Sylvie Doublié, Erik Johansson, Dale A Ramsden,[...]. PLoS Genet 2014
165
33

Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks.
David W Wyatt, Wanjuan Feng, Michael P Conlin, Matthew J Yousefzadeh, Steven A Roberts, Piotr Mieczkowski, Richard D Wood, Gaorav P Gupta, Dale A Ramsden. Mol Cell 2016
156
32

Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells.
Lan N Truong, Yongjiang Li, Linda Z Shi, Patty Yi-Hwa Hwang, Jing He, Hailong Wang, Niema Razavian, Michael W Berns, Xiaohua Wu. Proc Natl Acad Sci U S A 2013
292
31

The helicase domain of Polθ counteracts RPA to promote alt-NHEJ.
Pedro A Mateos-Gomez, Tatiana Kent, Sarah K Deng, Shane McDevitt, Ekaterina Kashkina, Trung M Hoang, Richard T Pomerantz, Agnel Sfeir. Nat Struct Mol Biol 2017
84
36

Non-homologous DNA end joining and alternative pathways to double-strand break repair.
Howard H Y Chang, Nicholas R Pannunzio, Noritaka Adachi, Michael R Lieber. Nat Rev Mol Cell Biol 2017
745
30



Human DNA polymerase θ grasps the primer terminus to mediate DNA repair.
Karl E Zahn, April M Averill, Pierre Aller, Richard D Wood, Sylvie Doublié. Nat Struct Mol Biol 2015
83
27

Mechanistic basis for microhomology identification and genome scarring by polymerase theta.
Juan Carvajal-Garcia, Jang-Eun Cho, Pablo Carvajal-Garcia, Wanjuan Feng, Richard D Wood, Jeff Sekelsky, Gaorav P Gupta, Steven A Roberts, Dale A Ramsden. Proc Natl Acad Sci U S A 2020
60
38

DNA polymerase θ (POLQ), double-strand break repair, and cancer.
Richard D Wood, Sylvie Doublié. DNA Repair (Amst) 2016
119
22


POLQ (Pol theta), a DNA polymerase and DNA-dependent ATPase in human cells.
Mineaki Seki, Federica Marini, Richard D Wood. Nucleic Acids Res 2003
137
22

Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair.
Nicole Bennardo, Anita Cheng, Nick Huang, Jeremy M Stark. PLoS Genet 2008
585
21


Genetic determinants of cellular addiction to DNA polymerase theta.
Wanjuan Feng, Dennis A Simpson, Juan Carvajal-Garcia, Brandon A Price, Rashmi J Kumar, Lisle E Mose, Richard D Wood, Naim Rashid, Jeremy E Purvis, Joel S Parker,[...]. Nat Commun 2019
62
32

Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway.
Joseph A Newman, Christopher D O Cooper, Hazel Aitkenhead, Opher Gileadi. Structure 2015
47
38

A Polymerase Theta-dependent repair pathway suppresses extensive genomic instability at endogenous G4 DNA sites.
Wouter Koole, Robin van Schendel, Andrea E Karambelas, Jane T van Heteren, Kristy L Okihara, Marcel Tijsterman. Nat Commun 2014
149
18

Repair Pathway Choices and Consequences at the Double-Strand Break.
Raphael Ceccaldi, Beatrice Rondinelli, Alan D D'Andrea. Trends Cell Biol 2016
789
17


Microhomology-mediated end joining: Good, bad and ugly.
Ja-Hwan Seol, Eun Yong Shim, Sang Eun Lee. Mutat Res 2018
121
17

PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways.
Minli Wang, Weizhong Wu, Wenqi Wu, Bustanur Rosidi, Lihua Zhang, Huichen Wang, George Iliakis. Nucleic Acids Res 2006
554
16

Regulation of Single-Strand Annealing and its Role in Genome Maintenance.
Ragini Bhargava, David O Onyango, Jeremy M Stark. Trends Genet 2016
235
16

Polymerase θ is a robust terminal transferase that oscillates between three different mechanisms during end-joining.
Tatiana Kent, Pedro A Mateos-Gomez, Agnel Sfeir, Richard T Pomerantz. Elife 2016
53
30

Inactivation of Pol θ and C-NHEJ eliminates off-target integration of exogenous DNA.
Alex N Zelensky, Joost Schimmel, Hanneke Kool, Roland Kanaar, Marcel Tijsterman. Nat Commun 2017
72
22

Drosophila DNA polymerase theta utilizes both helicase-like and polymerase domains during microhomology-mediated end joining and interstrand crosslink repair.
Kelly Beagan, Robin L Armstrong, Alice Witsell, Upasana Roy, Nikolai Renedo, Amy E Baker, Orlando D Schärer, Mitch McVey. PLoS Genet 2017
33
48

DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation.
Deniz Simsek, Erika Brunet, Sunnie Yan-Wai Wong, Sachin Katyal, Yankun Gao, Peter J McKinnon, Jacqueline Lou, Lei Zhang, James Li, Edward J Rebar,[...]. PLoS Genet 2011
207
16

Mutational signatures of non-homologous and polymerase theta-mediated end-joining in embryonic stem cells.
Joost Schimmel, Hanneke Kool, Robin van Schendel, Marcel Tijsterman. EMBO J 2017
74
21

DNA double-strand break repair-pathway choice in somatic mammalian cells.
Ralph Scully, Arvind Panday, Rajula Elango, Nicholas A Willis. Nat Rev Mol Cell Biol 2019
464
16

RPA antagonizes microhomology-mediated repair of DNA double-strand breaks.
Sarah K Deng, Bryan Gibb, Mariana Justino de Almeida, Eric C Greene, Lorraine S Symington. Nat Struct Mol Biol 2014
118
15

DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability.
Fanny Lemée, Valérie Bergoglio, Anne Fernandez-Vidal, Alice Machado-Silva, Marie-Jeanne Pillaire, Anne Bieth, Catherine Gentil, Lee Baker, Anne-Laure Martin, Claire Leduc,[...]. Proc Natl Acad Sci U S A 2010
117
15

Molecular basis of microhomology-mediated end-joining by purified full-length Polθ.
Samuel J Black, Ahmet Y Ozdemir, Ekaterina Kashkina, Tatiana Kent, Timur Rusanov, Dejan Ristic, Yeonoh Shin, Antonio Suma, Trung Hoang, Gurushankar Chandramouly,[...]. Nat Commun 2019
35
42

Homology and enzymatic requirements of microhomology-dependent alternative end joining.
S Sharma, S M Javadekar, M Pandey, M Srivastava, R Kumari, S C Raghavan. Cell Death Dis 2015
96
14


Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase.
Helen E Bryant, Niklas Schultz, Huw D Thomas, Kayan M Parker, Dan Flower, Elena Lopez, Suzanne Kyle, Mark Meuth, Nicola J Curtin, Thomas Helleday. Nature 2005
14

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.
Hannah Farmer, Nuala McCabe, Christopher J Lord, Andrew N J Tutt, Damian A Johnson, Tobias B Richardson, Manuela Santarosa, Krystyna J Dillon, Ian Hickson, Charlotte Knights,[...]. Nature 2005
14



53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks.
Samuel F Bunting, Elsa Callén, Nancy Wong, Hua-Tang Chen, Federica Polato, Amanda Gunn, Anne Bothmer, Niklas Feldhahn, Oscar Fernandez-Capetillo, Liu Cao,[...]. Cell 2010
14

DNA polymerase θ (POLQ) is important for repair of DNA double-strand breaks caused by fork collapse.
Zi Wang, Yadong Song, Shibo Li, Sunil Kurian, Rong Xiang, Takuya Chiba, Xiaohua Wu. J Biol Chem 2019
49
28

Low-fidelity DNA synthesis by human DNA polymerase theta.
Mercedes E Arana, Mineaki Seki, Richard D Wood, Igor B Rogozin, Thomas A Kunkel. Nucleic Acids Res 2008
99
14

Polymerase theta-mediated end joining of replication-associated DNA breaks in C. elegans.
Sophie F Roerink, Robin van Schendel, Marcel Tijsterman. Genome Res 2014
98
13


Lesion bypass activity of DNA polymerase θ (POLQ) is an intrinsic property of the pol domain and depends on unique sequence inserts.
Matthew Hogg, Mineaki Seki, Richard D Wood, Sylvie Doublié, Susan S Wallace. J Mol Biol 2011
62
20

A role for human homologous recombination factors in suppressing microhomology-mediated end joining.
Sara Ahrabi, Sovan Sarkar, Sophia X Pfister, Giacomo Pirovano, Geoff S Higgins, Andrew C G Porter, Timothy C Humphrey. Nucleic Acids Res 2016
58
22

High-efficiency bypass of DNA damage by human DNA polymerase Q.
Mineaki Seki, Chikahide Masutani, Lee Wei Yang, Anthony Schuffert, Shigenori Iwai, Ivet Bahar, Richard D Wood. EMBO J 2004
152
13

Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.
Kristen E Mengwasser, Richard O Adeyemi, Yumei Leng, Mei Yuk Choi, Connor Clairmont, Alan D D'Andrea, Stephen J Elledge. Mol Cell 2019
90
14

Template and primer requirements for DNA Pol θ-mediated end joining.
Peng He, Wei Yang. Proc Natl Acad Sci U S A 2018
21
61



Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.