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Times Cited: 983
Times Cited: 983
Times Cited
Times Co-cited
Similarity
Premature ageing in mice expressing defective mitochondrial DNA polymerase.
Aleksandra Trifunovic, Anna Wredenberg, Maria Falkenberg, Johannes N Spelbrink, Anja T Rovio, Carl E Bruder, Mohammad Bohlooly-Y, Sebastian Gidlöf, Anders Oldfors, Rolf Wibom,[...]. Nature 2004
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Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging.
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The hallmarks of aging.
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A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine.
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DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice.
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Sequence and organization of the human mitochondrial genome.
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Mitochondrial point mutations do not limit the natural lifespan of mice.
Marc Vermulst, Jason H Bielas, Gregory C Kujoth, Warren C Ladiges, Peter S Rabinovitch, Tomas A Prolla, Lawrence A Loeb. Nat Genet 2007
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Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production.
Aleksandra Trifunovic, Anna Hansson, Anna Wredenberg, Anja T Rovio, Eric Dufour, Ivan Khvorostov, Johannes N Spelbrink, Rolf Wibom, Howard T Jacobs, Nils-Göran Larsson. Proc Natl Acad Sci U S A 2005
Aleksandra Trifunovic, Anna Hansson, Anna Wredenberg, Anja T Rovio, Eric Dufour, Ivan Khvorostov, Johannes N Spelbrink, Rolf Wibom, Howard T Jacobs, Nils-Göran Larsson. Proc Natl Acad Sci U S A 2005
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Extension of murine life span by overexpression of catalase targeted to mitochondria.
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Mitochondrial DNA-deletion mutations accumulate intracellularly to detrimental levels in aged human skeletal muscle fibers.
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High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease.
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Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons.
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Mitochondrial DNA mutations induce mitochondrial dysfunction, apoptosis and sarcopenia in skeletal muscle of mitochondrial DNA mutator mice.
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Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases.
Michael T Lin, M Flint Beal. Nature 2006
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Germline mitochondrial DNA mutations aggravate ageing and can impair brain development.
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Somatic progenitor cell vulnerability to mitochondrial DNA mutagenesis underlies progeroid phenotypes in Polg mutator mice.
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Mitochondrial aging and age-related dysfunction of mitochondria.
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Random point mutations with major effects on protein-coding genes are the driving force behind premature aging in mtDNA mutator mice.
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Placental mitochondrial DNA content and particulate air pollution during in utero life.
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Mitochondrial role in cell aging.
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Extending healthy life span--from yeast to humans.
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7
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders.
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Darren J Baker, Tobias Wijshake, Tamar Tchkonia, Nathan K LeBrasseur, Bennett G Childs, Bart van de Sluis, James L Kirkland, Jan M van Deursen. Nature 2011
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Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan.
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Mitochondrial dysfunction in the elderly: possible role in insulin resistance.
Kitt Falk Petersen, Douglas Befroy, Sylvie Dufour, James Dziura, Charlotte Ariyan, Douglas L Rothman, Loretta DiPietro, Gary W Cline, Gerald I Shulman. Science 2003
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Role of the mitochondrial DNA replication machinery in mitochondrial DNA mutagenesis, aging and age-related diseases.
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Cellular senescence: when bad things happen to good cells.
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Reducing mitochondrial fission results in increased life span and fitness of two fungal ageing models.
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Age-dependent dissociation of ATP synthase dimers and loss of inner-membrane cristae in mitochondria.
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Ultra-sensitive sequencing reveals an age-related increase in somatic mitochondrial mutations that are inconsistent with oxidative damage.
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Mitochondrial DNA genetics and the heteroplasmy conundrum in evolution and disease.
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Universal heteroplasmy of human mitochondrial DNA.
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Brendan A I Payne, Ian J Wilson, Patrick Yu-Wai-Man, Jonathan Coxhead, David Deehan, Rita Horvath, Robert W Taylor, David C Samuels, Mauro Santibanez-Koref, Patrick F Chinnery. Hum Mol Genet 2013
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Mitochondrial DNA mutations in disease and aging.
Chan Bae Park, Nils-Göran Larsson. J Cell Biol 2011
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Caloric restriction delays disease onset and mortality in rhesus monkeys.
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Autophagy maintains stemness by preventing senescence.
Laura García-Prat, Marta Martínez-Vicente, Eusebio Perdiguero, Laura Ortet, Javier Rodríguez-Ubreva, Elena Rebollo, Vanessa Ruiz-Bonilla, Susana Gutarra, Esteban Ballestar, Antonio L Serrano,[...]. Nature 2016
Laura García-Prat, Marta Martínez-Vicente, Eusebio Perdiguero, Laura Ortet, Javier Rodríguez-Ubreva, Elena Rebollo, Vanessa Ruiz-Bonilla, Susana Gutarra, Esteban Ballestar, Antonio L Serrano,[...]. Nature 2016
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Mitochondrial quality control: an integrated network of pathways.
Fabian Fischer, Andrea Hamann, Heinz D Osiewacz. Trends Biochem Sci 2012
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Fission and selective fusion govern mitochondrial segregation and elimination by autophagy.
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Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.