Heather A O'Malley, Lori L Isom. Annu Rev Physiol 2015
Times Cited: 147
Times Cited: 147
Times Cited
Times Co-cited
Similarity
Na Channel β Subunits: Overachievers of the Ion Channel Family.
William J Brackenbury, Lori L Isom. Front Pharmacol 2011
William J Brackenbury, Lori L Isom. Front Pharmacol 2011
25
Voltage-gated sodium channels at 60: structure, function and pathophysiology.
William A Catterall. J Physiol 2012
William A Catterall. J Physiol 2012
22
International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.
William A Catterall, Alan L Goldin, Stephen G Waxman. Pharmacol Rev 2005
William A Catterall, Alan L Goldin, Stephen G Waxman. Pharmacol Rev 2005
19
A functional null mutation of SCN1B in a patient with Dravet syndrome.
Gustavo A Patino, Lieve R F Claes, Luis F Lopez-Santiago, Emily A Slat, Raja S R Dondeti, Chunling Chen, Heather A O'Malley, Charles B B Gray, Haruko Miyazaki, Nobuyuki Nukina,[...]. J Neurosci 2009
Gustavo A Patino, Lieve R F Claes, Luis F Lopez-Santiago, Emily A Slat, Raja S R Dondeti, Chunling Chen, Heather A O'Malley, Charles B B Gray, Haruko Miyazaki, Nobuyuki Nukina,[...]. J Neurosci 2009
18
Sodium channel β1 subunit mutations associated with Brugada syndrome and cardiac conduction disease in humans.
Hiroshi Watanabe, Tamara T Koopmann, Solena Le Scouarnec, Tao Yang, Christiana R Ingram, Jean-Jacques Schott, Sophie Demolombe, Vincent Probst, Frédéric Anselme, Denis Escande,[...]. J Clin Invest 2008
Hiroshi Watanabe, Tamara T Koopmann, Solena Le Scouarnec, Tao Yang, Christiana R Ingram, Jean-Jacques Schott, Sophie Demolombe, Vincent Probst, Frédéric Anselme, Denis Escande,[...]. J Clin Invest 2008
18
The role of non-pore-forming β subunits in physiology and pathophysiology of voltage-gated sodium channels.
Jeffrey D Calhoun, Lori L Isom. Handb Exp Pharmacol 2014
Jeffrey D Calhoun, Lori L Isom. Handb Exp Pharmacol 2014
24
Structures of human Nav1.7 channel in complex with auxiliary subunits and animal toxins.
Huaizong Shen, Dongliang Liu, Kun Wu, Jianlin Lei, Nieng Yan. Science 2019
Huaizong Shen, Dongliang Liu, Kun Wu, Jianlin Lei, Nieng Yan. Science 2019
18
Voltage-gated Na+ channel β1B: a secreted cell adhesion molecule involved in human epilepsy.
Gustavo A Patino, William J Brackenbury, Yangyang Bao, Luis F Lopez-Santiago, Heather A O'Malley, Chunling Chen, Jeffrey D Calhoun, Ron G Lafrenière, Patrick Cossette, Guy A Rouleau,[...]. J Neurosci 2011
Gustavo A Patino, William J Brackenbury, Yangyang Bao, Luis F Lopez-Santiago, Heather A O'Malley, Chunling Chen, Jeffrey D Calhoun, Ron G Lafrenière, Patrick Cossette, Guy A Rouleau,[...]. J Neurosci 2011
22
From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels.
W A Catterall. Neuron 2000
W A Catterall. Neuron 2000
17
Structure of a eukaryotic voltage-gated sodium channel at near-atomic resolution.
Huaizong Shen, Qiang Zhou, Xiaojing Pan, Zhangqiang Li, Jianping Wu, Nieng Yan. Science 2017
Huaizong Shen, Qiang Zhou, Xiaojing Pan, Zhangqiang Li, Jianping Wu, Nieng Yan. Science 2017
17
Structure of the human voltage-gated sodium channel Nav1.4 in complex with β1.
Xiaojing Pan, Zhangqiang Li, Qiang Zhou, Huaizong Shen, Kun Wu, Xiaoshuang Huang, Jiaofeng Chen, Juanrong Zhang, Xuechen Zhu, Jianlin Lei,[...]. Science 2018
Xiaojing Pan, Zhangqiang Li, Qiang Zhou, Huaizong Shen, Kun Wu, Xiaoshuang Huang, Jiaofeng Chen, Juanrong Zhang, Xuechen Zhu, Jianlin Lei,[...]. Science 2018
17
Mice lacking sodium channel beta1 subunits display defects in neuronal excitability, sodium channel expression, and nodal architecture.
Chunling Chen, Ruth E Westenbroek, Xiaorong Xu, Chris A Edwards, Dorothy R Sorenson, Yuan Chen, Dyke P McEwen, Heather A O'Malley, Vandana Bharucha, Laurence S Meadows,[...]. J Neurosci 2004
Chunling Chen, Ruth E Westenbroek, Xiaorong Xu, Chris A Edwards, Dorothy R Sorenson, Yuan Chen, Dyke P McEwen, Heather A O'Malley, Vandana Bharucha, Laurence S Meadows,[...]. J Neurosci 2004
16
Structure of the Nav1.4-β1 Complex from Electric Eel.
Zhen Yan, Qiang Zhou, Lin Wang, Jianping Wu, Yanyu Zhao, Gaoxingyu Huang, Wei Peng, Huaizong Shen, Jianlin Lei, Nieng Yan. Cell 2017
Zhen Yan, Qiang Zhou, Lin Wang, Jianping Wu, Yanyu Zhao, Gaoxingyu Huang, Wei Peng, Huaizong Shen, Jianlin Lei, Nieng Yan. Cell 2017
15
Febrile seizures and generalized epilepsy associated with a mutation in the Na+-channel beta1 subunit gene SCN1B.
R H Wallace, D W Wang, R Singh, I E Scheffer, A L George, H A Phillips, K Saar, A Reis, E W Johnson, G R Sutherland,[...]. Nat Genet 1998
R H Wallace, D W Wang, R Singh, I E Scheffer, A L George, H A Phillips, K Saar, A Reis, E W Johnson, G R Sutherland,[...]. Nat Genet 1998
14
Molecular basis for pore blockade of human Na+ channel Nav1.2 by the μ-conotoxin KIIIA.
Xiaojing Pan, Zhangqiang Li, Xiaoshuang Huang, Gaoxingyu Huang, Shuai Gao, Huaizong Shen, Lei Liu, Jianlin Lei, Nieng Yan. Science 2019
Xiaojing Pan, Zhangqiang Li, Xiaoshuang Huang, Gaoxingyu Huang, Shuai Gao, Huaizong Shen, Lei Liu, Jianlin Lei, Nieng Yan. Science 2019
14
Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy.
Frank H Yu, Massimo Mantegazza, Ruth E Westenbroek, Carol A Robbins, Franck Kalume, Kimberly A Burton, William J Spain, G Stanley McKnight, Todd Scheuer, William A Catterall. Nat Neurosci 2006
Frank H Yu, Massimo Mantegazza, Ruth E Westenbroek, Carol A Robbins, Franck Kalume, Kimberly A Burton, William J Spain, G Stanley McKnight, Todd Scheuer, William A Catterall. Nat Neurosci 2006
13
De novo pathogenic SCN8A mutation identified by whole-genome sequencing of a family quartet affected by infantile epileptic encephalopathy and SUDEP.
Krishna R Veeramah, Janelle E O'Brien, Miriam H Meisler, Xiaoyang Cheng, Sulayman D Dib-Hajj, Stephen G Waxman, Dinesh Talwar, Santhosh Girirajan, Evan E Eichler, Linda L Restifo,[...]. Am J Hum Genet 2012
Krishna R Veeramah, Janelle E O'Brien, Miriam H Meisler, Xiaoyang Cheng, Sulayman D Dib-Hajj, Stephen G Waxman, Dinesh Talwar, Santhosh Girirajan, Evan E Eichler, Linda L Restifo,[...]. Am J Hum Genet 2012
13
β1-C121W Is Down But Not Out: Epilepsy-Associated Scn1b-C121W Results in a Deleterious Gain-of-Function.
Larisa C Kruger, Heather A O'Malley, Jacob M Hull, Amanda Kleeman, Gustavo A Patino, Lori L Isom. J Neurosci 2016
Larisa C Kruger, Heather A O'Malley, Jacob M Hull, Amanda Kleeman, Gustavo A Patino, Lori L Isom. J Neurosci 2016
48
Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel.
L L Isom, K S De Jongh, D E Patton, B F Reber, J Offord, H Charbonneau, K Walsh, A L Goldin, W A Catterall. Science 1992
L L Isom, K S De Jongh, D E Patton, B F Reber, J Offord, H Charbonneau, K Walsh, A L Goldin, W A Catterall. Science 1992
13
beta Subunits of voltage-gated sodium channels are novel substrates of beta-site amyloid precursor protein-cleaving enzyme (BACE1) and gamma-secretase.
Hon-Kit Wong, Takashi Sakurai, Fumitaka Oyama, Kumi Kaneko, Koji Wada, Haruko Miyazaki, Masaru Kurosawa, Bart De Strooper, Paul Saftig, Nobuyuki Nukina. J Biol Chem 2005
Hon-Kit Wong, Takashi Sakurai, Fumitaka Oyama, Kumi Kaneko, Koji Wada, Haruko Miyazaki, Masaru Kurosawa, Bart De Strooper, Paul Saftig, Nobuyuki Nukina. J Biol Chem 2005
13
The sodium channel accessory subunit Navβ1 regulates neuronal excitability through modulation of repolarizing voltage-gated K⁺ channels.
Céline Marionneau, Yarimar Carrasquillo, Aaron J Norris, R Reid Townsend, Lori L Isom, Andrew J Link, Jeanne M Nerbonne. J Neurosci 2012
Céline Marionneau, Yarimar Carrasquillo, Aaron J Norris, R Reid Townsend, Lori L Isom, Andrew J Link, Jeanne M Nerbonne. J Neurosci 2012
17
The crystal structure of a voltage-gated sodium channel.
Jian Payandeh, Todd Scheuer, Ning Zheng, William A Catterall. Nature 2011
Jian Payandeh, Todd Scheuer, Ning Zheng, William A Catterall. Nature 2011
12
A homozygous mutation of voltage-gated sodium channel β(I) gene SCN1B in a patient with Dravet syndrome.
Ikuo Ogiwara, Tojo Nakayama, Tetsushi Yamagata, Hideyuki Ohtani, Emi Mazaki, Shigeru Tsuchiya, Yushi Inoue, Kazuhiro Yamakawa. Epilepsia 2012
Ikuo Ogiwara, Tojo Nakayama, Tetsushi Yamagata, Hideyuki Ohtani, Emi Mazaki, Shigeru Tsuchiya, Yushi Inoue, Kazuhiro Yamakawa. Epilepsia 2012
20
Confirming the recessive inheritance of SCN1B mutations in developmental epileptic encephalopathy.
W Ramadan, N Patel, S Anazi, A Y Kentab, F A Bashiri, M H Hamad, L Jad, M A Salih, H Alsaif, M Hashem,[...]. Clin Genet 2017
W Ramadan, N Patel, S Anazi, A Y Kentab, F A Bashiri, M H Hamad, L Jad, M A Salih, H Alsaif, M Hashem,[...]. Clin Genet 2017
46
Identification of the cysteine residue responsible for disulfide linkage of Na+ channel α and β2 subunits.
Chunling Chen, Jeffrey D Calhoun, Yanqing Zhang, Luis Lopez-Santiago, Ningna Zhou, Tigwa H Davis, James L Salzer, Lori L Isom. J Biol Chem 2012
Chunling Chen, Jeffrey D Calhoun, Yanqing Zhang, Luis Lopez-Santiago, Ningna Zhou, Tigwa H Davis, James L Salzer, Lori L Isom. J Biol Chem 2012
21
Temporal lobe epilepsy and GEFS+ phenotypes associated with SCN1B mutations.
Ingrid E Scheffer, Louise A Harkin, Bronwyn E Grinton, Leanne M Dibbens, Samantha J Turner, Marta A Zielinski, Ruwei Xu, Graeme Jackson, Judith Adams, Mary Connellan,[...]. Brain 2007
Ingrid E Scheffer, Louise A Harkin, Bronwyn E Grinton, Leanne M Dibbens, Samantha J Turner, Marta A Zielinski, Ruwei Xu, Graeme Jackson, Judith Adams, Mary Connellan,[...]. Brain 2007
12
Mutations in sodium channel β1- and β2-subunits associated with atrial fibrillation.
Hiroshi Watanabe, Dawood Darbar, Daniel W Kaiser, Kim Jiramongkolchai, Sameer Chopra, Brian S Donahue, Prince J Kannankeril, Dan M Roden. Circ Arrhythm Electrophysiol 2009
Hiroshi Watanabe, Dawood Darbar, Daniel W Kaiser, Kim Jiramongkolchai, Sameer Chopra, Brian S Donahue, Prince J Kannankeril, Dan M Roden. Circ Arrhythm Electrophysiol 2009
12
Crystallographic insights into sodium-channel modulation by the β4 subunit.
John Gilchrist, Samir Das, Filip Van Petegem, Frank Bosmans. Proc Natl Acad Sci U S A 2013
John Gilchrist, Samir Das, Filip Van Petegem, Frank Bosmans. Proc Natl Acad Sci U S A 2013
16
Scn1b deletion leads to increased tetrodotoxin-sensitive sodium current, altered intracellular calcium homeostasis and arrhythmias in murine hearts.
Xianming Lin, Heather O'Malley, Chunling Chen, David Auerbach, Monique Foster, Akshay Shekhar, Mingliang Zhang, William Coetzee, José Jalife, Glenn I Fishman,[...]. J Physiol 2015
Xianming Lin, Heather O'Malley, Chunling Chen, David Auerbach, Monique Foster, Akshay Shekhar, Mingliang Zhang, William Coetzee, José Jalife, Glenn I Fishman,[...]. J Physiol 2015
22
A new look at sodium channel β subunits.
Sivakumar Namadurai, Nikitha R Yereddi, Fiona S Cusdin, Christopher L H Huang, Dimitri Y Chirgadze, Antony P Jackson. Open Biol 2015
Sivakumar Namadurai, Nikitha R Yereddi, Fiona S Cusdin, Christopher L H Huang, Dimitri Y Chirgadze, Antony P Jackson. Open Biol 2015
17
Sodium channel beta subunits mediate homophilic cell adhesion and recruit ankyrin to points of cell-cell contact.
J D Malhotra, K Kazen-Gillespie, M Hortsch, L L Isom. J Biol Chem 2000
J D Malhotra, K Kazen-Gillespie, M Hortsch, L L Isom. J Biol Chem 2000
11
Regulation of persistent Na current by interactions between beta subunits of voltage-gated Na channels.
Teresa K Aman, Tina M Grieco-Calub, Chunling Chen, Raffaella Rusconi, Emily A Slat, Lori L Isom, Indira M Raman. J Neurosci 2009
Teresa K Aman, Tina M Grieco-Calub, Chunling Chen, Raffaella Rusconi, Emily A Slat, Lori L Isom, Indira M Raman. J Neurosci 2009
11
The hitchhiker's guide to the voltage-gated sodium channel galaxy.
Christopher A Ahern, Jian Payandeh, Frank Bosmans, Baron Chanda. J Gen Physiol 2016
Christopher A Ahern, Jian Payandeh, Frank Bosmans, Baron Chanda. J Gen Physiol 2016
11
Mechanisms of noncovalent β subunit regulation of NaV channel gating.
Wandi Zhu, Taylor L Voelker, Zoltan Varga, Angela R Schubert, Jeanne M Nerbonne, Jonathan R Silva. J Gen Physiol 2017
Wandi Zhu, Taylor L Voelker, Zoltan Varga, Angela R Schubert, Jeanne M Nerbonne, Jonathan R Silva. J Gen Physiol 2017
23
Voltage-Gated Sodium Channel β Subunits and Their Related Diseases.
Alexandra A Bouza, Lori L Isom. Handb Exp Pharmacol 2018
Alexandra A Bouza, Lori L Isom. Handb Exp Pharmacol 2018
27
BACE1 regulates voltage-gated sodium channels and neuronal activity.
Doo Yeon Kim, Bryce W Carey, Haibin Wang, Laura A M Ingano, Alexander M Binshtok, Mary H Wertz, Warren H Pettingell, Ping He, Virginia M-Y Lee, Clifford J Woolf,[...]. Nat Cell Biol 2007
Doo Yeon Kim, Bryce W Carey, Haibin Wang, Laura A M Ingano, Alexander M Binshtok, Mary H Wertz, Warren H Pettingell, Ping He, Virginia M-Y Lee, Clifford J Woolf,[...]. Nat Cell Biol 2007
10
Modulation of voltage-gated K+ channels by the sodium channel β1 subunit.
Hai M Nguyen, Haruko Miyazaki, Naoto Hoshi, Brian J Smith, Nobuyuki Nukina, Alan L Goldin, K George Chandy. Proc Natl Acad Sci U S A 2012
Hai M Nguyen, Haruko Miyazaki, Naoto Hoshi, Brian J Smith, Nobuyuki Nukina, Alan L Goldin, K George Chandy. Proc Natl Acad Sci U S A 2012
22
Crystal structure and molecular imaging of the Nav channel β3 subunit indicates a trimeric assembly.
Sivakumar Namadurai, Dilshan Balasuriya, Rajit Rajappa, Martin Wiemhöfer, Katherine Stott, Jurgen Klingauf, J Michael Edwardson, Dimitri Y Chirgadze, Antony P Jackson. J Biol Chem 2014
Sivakumar Namadurai, Dilshan Balasuriya, Rajit Rajappa, Martin Wiemhöfer, Katherine Stott, Jurgen Klingauf, J Michael Edwardson, Dimitri Y Chirgadze, Antony P Jackson. J Biol Chem 2014
19
Abnormal neuronal patterning occurs during early postnatal brain development of Scn1b-null mice and precedes hyperexcitability.
William J Brackenbury, Yukun Yuan, Heather A O'Malley, Jack M Parent, Lori L Isom. Proc Natl Acad Sci U S A 2013
William J Brackenbury, Yukun Yuan, Heather A O'Malley, Jack M Parent, Lori L Isom. Proc Natl Acad Sci U S A 2013
19
Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals.
Luis F Lopez-Santiago, Laurence S Meadows, Sara J Ernst, Chunling Chen, Jyoti Dhar Malhotra, Dyke P McEwen, Audrey Speelman, Jeffrey L Noebels, Sebastian K G Maier, Anatoli N Lopatin,[...]. J Mol Cell Cardiol 2007
Luis F Lopez-Santiago, Laurence S Meadows, Sara J Ernst, Chunling Chen, Jyoti Dhar Malhotra, Dyke P McEwen, Audrey Speelman, Jeffrey L Noebels, Sebastian K G Maier, Anatoli N Lopatin,[...]. J Mol Cell Cardiol 2007
10
Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.
Ikuo Ogiwara, Hiroyuki Miyamoto, Noriyuki Morita, Nafiseh Atapour, Emi Mazaki, Ikuyo Inoue, Tamaki Takeuchi, Shigeyoshi Itohara, Yuchio Yanagawa, Kunihiko Obata,[...]. J Neurosci 2007
Ikuo Ogiwara, Hiroyuki Miyamoto, Noriyuki Morita, Nafiseh Atapour, Emi Mazaki, Ikuyo Inoue, Tamaki Takeuchi, Shigeyoshi Itohara, Yuchio Yanagawa, Kunihiko Obata,[...]. J Neurosci 2007
10
A quantitative description of membrane current and its application to conduction and excitation in nerve.
A L HODGKIN, A F HUXLEY. J Physiol 1952
A L HODGKIN, A F HUXLEY. J Physiol 1952
10
Structure-based assessment of disease-related mutations in human voltage-gated sodium channels.
Weiyun Huang, Minhao Liu, S Frank Yan, Nieng Yan. Protein Cell 2017
Weiyun Huang, Minhao Liu, S Frank Yan, Nieng Yan. Protein Cell 2017
12
Binary architecture of the Nav1.2-β2 signaling complex.
Samir Das, John Gilchrist, Frank Bosmans, Filip Van Petegem. Elife 2016
Samir Das, John Gilchrist, Frank Bosmans, Filip Van Petegem. Elife 2016
27
A deletion in SCN1B is associated with febrile seizures and early-onset absence epilepsy.
D Audenaert, L Claes, B Ceulemans, A Löfgren, C Van Broeckhoven, P De Jonghe. Neurology 2003
D Audenaert, L Claes, B Ceulemans, A Löfgren, C Van Broeckhoven, P De Jonghe. Neurology 2003
9
A missense mutation in the sodium channel β1b subunit reveals SCN1B as a susceptibility gene underlying long QT syndrome.
Helena Riuró, Oscar Campuzano, Elena Arbelo, Anna Iglesias, Montserrat Batlle, Felix Pérez-Villa, Josep Brugada, Guillermo J Pérez, Fabiana S Scornik, Ramon Brugada. Heart Rhythm 2014
Helena Riuró, Oscar Campuzano, Elena Arbelo, Anna Iglesias, Montserrat Batlle, Felix Pérez-Villa, Josep Brugada, Guillermo J Pérez, Fabiana S Scornik, Ramon Brugada. Heart Rhythm 2014
30
Genetic and phenotypic heterogeneity suggest therapeutic implications in SCN2A-related disorders.
Markus Wolff, Katrine M Johannesen, Ulrike B S Hedrich, Silvia Masnada, Guido Rubboli, Elena Gardella, Gaetan Lesca, Dorothée Ville, Mathieu Milh, Laurent Villard,[...]. Brain 2017
Markus Wolff, Katrine M Johannesen, Ulrike B S Hedrich, Silvia Masnada, Guido Rubboli, Elena Gardella, Gaetan Lesca, Dorothée Ville, Mathieu Milh, Laurent Villard,[...]. Brain 2017
9
A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation.
J W West, D E Patton, T Scheuer, Y Wang, A L Goldin, W A Catterall. Proc Natl Acad Sci U S A 1992
J W West, D E Patton, T Scheuer, Y Wang, A L Goldin, W A Catterall. Proc Natl Acad Sci U S A 1992
9
Nomenclature of voltage-gated sodium channels.
A L Goldin, R L Barchi, J H Caldwell, F Hofmann, J R Howe, J C Hunter, R G Kallen, G Mandel, M H Meisler, Y B Netter,[...]. Neuron 2000
A L Goldin, R L Barchi, J H Caldwell, F Hofmann, J R Howe, J C Hunter, R G Kallen, G Mandel, M H Meisler, Y B Netter,[...]. Neuron 2000
9
Domain IV voltage-sensor movement is both sufficient and rate limiting for fast inactivation in sodium channels.
Deborah L Capes, Marcel P Goldschen-Ohm, Manoel Arcisio-Miranda, Francisco Bezanilla, Baron Chanda. J Gen Physiol 2013
Deborah L Capes, Marcel P Goldschen-Ohm, Manoel Arcisio-Miranda, Francisco Bezanilla, Baron Chanda. J Gen Physiol 2013
9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.