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Times Cited: 304
Times Cited: 304
Times Cited
Times Co-cited
Similarity
The DNA-damage response in human biology and disease.
Stephen P Jackson, Jiri Bartek. Nature 2009
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State-of-the-art strategies for targeting the DNA damage response in cancer.
Patrick G Pilié, Chad Tang, Gordon B Mills, Timothy A Yap. Nat Rev Clin Oncol 2019
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Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas.
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Targeting DNA Repair in Cancer: Beyond PARP Inhibitors.
Jessica S Brown, Brent O'Carrigan, Stephen P Jackson, Timothy A Yap. Cancer Discov 2017
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The DNA damage response: making it safe to play with knives.
Alberto Ciccia, Stephen J Elledge. Mol Cell 2010
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Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.
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Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase.
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DNA repair pathways as targets for cancer therapy.
Thomas Helleday, Eva Petermann, Cecilia Lundin, Ben Hodgson, Ricky A Sharma. Nat Rev Cancer 2008
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Andrew N Blackford, Stephen P Jackson. Mol Cell 2017
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DNA repair, genome stability and cancer: a historical perspective.
Penny A Jeggo, Laurence H Pearl, Antony M Carr. Nat Rev Cancer 2016
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PARP inhibitors: Synthetic lethality in the clinic.
Christopher J Lord, Alan Ashworth. Science 2017
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Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
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DNA repair dysregulation from cancer driver to therapeutic target.
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Mechanisms of DNA damage, repair, and mutagenesis.
Nimrat Chatterjee, Graham C Walker. Environ Mol Mutagen 2017
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Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors.
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The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer.
Joanne Smith, Lye Mun Tho, Naihan Xu, David A Gillespie. Adv Cancer Res 2010
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The effects of deregulated DNA damage signalling on cancer chemotherapy response and resistance.
Peter Bouwman, Jos Jonkers. Nat Rev Cancer 2012
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Non-homologous DNA end joining and alternative pathways to double-strand break repair.
Howard H Y Chang, Nicholas R Pannunzio, Noritaka Adachi, Michael R Lieber. Nat Rev Mol Cell Biol 2017
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Endogenous DNA Damage as a Source of Genomic Instability in Cancer.
Anthony Tubbs, André Nussenzweig. Cell 2017
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Olaparib monotherapy in patients with advanced cancer and a germline BRCA1/2 mutation.
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Pharmacology of the ATM Inhibitor AZD0156: Potentiation of Irradiation and Olaparib Responses Preclinically.
Lucy C Riches, Antonio G Trinidad, Gareth Hughes, Gemma N Jones, Adina M Hughes, Andrew G Thomason, Paul Gavine, Andy Cui, Stephanie Ling, Jonathan Stott,[...]. Mol Cancer Ther 2020
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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.
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Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints.
Aziz Sancar, Laura A Lindsey-Boltz, Keziban Unsal-Kaçmaz, Stuart Linn. Annu Rev Biochem 2004
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Understanding nucleotide excision repair and its roles in cancer and ageing.
Jurgen A Marteijn, Hannes Lans, Wim Vermeulen, Jan H J Hoeijmakers. Nat Rev Mol Cell Biol 2014
Jurgen A Marteijn, Hannes Lans, Wim Vermeulen, Jan H J Hoeijmakers. Nat Rev Mol Cell Biol 2014
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Glioma stem cells promote radioresistance by preferential activation of the DNA damage response.
Shideng Bao, Qiulian Wu, Roger E McLendon, Yueling Hao, Qing Shi, Anita B Hjelmeland, Mark W Dewhirst, Darell D Bigner, Jeremy N Rich. Nature 2006
Shideng Bao, Qiulian Wu, Roger E McLendon, Yueling Hao, Qing Shi, Anita B Hjelmeland, Mark W Dewhirst, Darell D Bigner, Jeremy N Rich. Nature 2006
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Genomic instability--an evolving hallmark of cancer.
Simona Negrini, Vassilis G Gorgoulis, Thanos D Halazonetis. Nat Rev Mol Cell Biol 2010
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DNA double-strand break repair-pathway choice in somatic mammalian cells.
Ralph Scully, Arvind Panday, Rajula Elango, Nicholas A Willis. Nat Rev Mol Cell Biol 2019
Ralph Scully, Arvind Panday, Rajula Elango, Nicholas A Willis. Nat Rev Mol Cell Biol 2019
7
The Fanconi Anemia Pathway in Cancer.
Joshi Niraj, Anniina Färkkilä, Alan D D'Andrea. Annu Rev Cancer Biol 2019
Joshi Niraj, Anniina Färkkilä, Alan D D'Andrea. Annu Rev Cancer Biol 2019
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DNA damage and the balance between survival and death in cancer biology.
Wynand P Roos, Adam D Thomas, Bernd Kaina. Nat Rev Cancer 2016
Wynand P Roos, Adam D Thomas, Bernd Kaina. Nat Rev Cancer 2016
7
DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer.
Joaquin Mateo, Suzanne Carreira, Shahneen Sandhu, Susana Miranda, Helen Mossop, Raquel Perez-Lopez, Daniel Nava Rodrigues, Dan Robinson, Aurelius Omlin, Nina Tunariu,[...]. N Engl J Med 2015
Joaquin Mateo, Suzanne Carreira, Shahneen Sandhu, Susana Miranda, Helen Mossop, Raquel Perez-Lopez, Daniel Nava Rodrigues, Dan Robinson, Aurelius Omlin, Nina Tunariu,[...]. N Engl J Med 2015
7
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis.
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7
Alterations in DNA Damage Response and Repair Genes as Potential Marker of Clinical Benefit From PD-1/PD-L1 Blockade in Advanced Urothelial Cancers.
Min Yuen Teo, Kenneth Seier, Irina Ostrovnaya, Ashley M Regazzi, Brooke E Kania, Meredith M Moran, Catharine K Cipolla, Mark J Bluth, Joshua Chaim, Hikmat Al-Ahmadie,[...]. J Clin Oncol 2018
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7
Maintenance Olaparib for Germline BRCA-Mutated Metastatic Pancreatic Cancer.
Talia Golan, Pascal Hammel, Michele Reni, Eric Van Cutsem, Teresa Macarulla, Michael J Hall, Joon-Oh Park, Daniel Hochhauser, Dirk Arnold, Do-Youn Oh,[...]. N Engl J Med 2019
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7
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.
Hyuna Sung, Jacques Ferlay, Rebecca L Siegel, Mathieu Laversanne, Isabelle Soerjomataram, Ahmedin Jemal, Freddie Bray. CA Cancer J Clin 2021
Hyuna Sung, Jacques Ferlay, Rebecca L Siegel, Mathieu Laversanne, Isabelle Soerjomataram, Ahmedin Jemal, Freddie Bray. CA Cancer J Clin 2021
7
Moving From Poly (ADP-Ribose) Polymerase Inhibition to Targeting DNA Repair and DNA Damage Response in Cancer Therapy.
Charlie Gourley, Judith Balmaña, Jonathan A Ledermann, Violeta Serra, Rebecca Dent, Sibylle Loibl, Eric Pujade-Lauraine, Simon J Boulton. J Clin Oncol 2019
Charlie Gourley, Judith Balmaña, Jonathan A Ledermann, Violeta Serra, Rebecca Dent, Sibylle Loibl, Eric Pujade-Lauraine, Simon J Boulton. J Clin Oncol 2019
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DNA damage sensing by the ATM and ATR kinases.
Alexandre Maréchal, Lee Zou. Cold Spring Harb Perspect Biol 2013
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Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1.
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2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity.
Parker L Sulkowski, Christopher D Corso, Nathaniel D Robinson, Susan E Scanlon, Karin R Purshouse, Hanwen Bai, Yanfeng Liu, Ranjini K Sundaram, Denise C Hegan, Nathan R Fons,[...]. Sci Transl Med 2017
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6
Targeting DNA Damage Response Promotes Antitumor Immunity through STING-Mediated T-cell Activation in Small Cell Lung Cancer.
Triparna Sen, B Leticia Rodriguez, Limo Chen, Carminia M Della Corte, Naoto Morikawa, Junya Fujimoto, Sandra Cristea, Thuyen Nguyen, Lixia Diao, Lerong Li,[...]. Cancer Discov 2019
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6
Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition.
Nuala McCabe, Nicholas C Turner, Christopher J Lord, Katarzyna Kluzek, Aneta Bialkowska, Sally Swift, Sabrina Giavara, Mark J O'Connor, Andrew N Tutt, Małgorzata Z Zdzienicka,[...]. Cancer Res 2006
Nuala McCabe, Nicholas C Turner, Christopher J Lord, Katarzyna Kluzek, Aneta Bialkowska, Sally Swift, Sabrina Giavara, Mark J O'Connor, Andrew N Tutt, Małgorzata Z Zdzienicka,[...]. Cancer Res 2006
6
Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade.
Dung T Le, Jennifer N Durham, Kellie N Smith, Hao Wang, Bjarne R Bartlett, Laveet K Aulakh, Steve Lu, Holly Kemberling, Cara Wilt, Brandon S Luber,[...]. Science 2017
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6
Veliparib with First-Line Chemotherapy and as Maintenance Therapy in Ovarian Cancer.
Robert L Coleman, Gini F Fleming, Mark F Brady, Elizabeth M Swisher, Karina D Steffensen, Michael Friedlander, Aikou Okamoto, Kathleen N Moore, Noa Efrat Ben-Baruch, Theresa L Werner,[...]. N Engl J Med 2019
Robert L Coleman, Gini F Fleming, Mark F Brady, Elizabeth M Swisher, Karina D Steffensen, Michael Friedlander, Aikou Okamoto, Kathleen N Moore, Noa Efrat Ben-Baruch, Theresa L Werner,[...]. N Engl J Med 2019
6
PARP Inhibitor Upregulates PD-L1 Expression and Enhances Cancer-Associated Immunosuppression.
Shiping Jiao, Weiya Xia, Hirohito Yamaguchi, Yongkun Wei, Mei-Kuang Chen, Jung-Mao Hsu, Jennifer L Hsu, Wen-Hsuan Yu, Yi Du, Heng-Huan Lee,[...]. Clin Cancer Res 2017
Shiping Jiao, Weiya Xia, Hirohito Yamaguchi, Yongkun Wei, Mei-Kuang Chen, Jung-Mao Hsu, Jennifer L Hsu, Wen-Hsuan Yu, Yi Du, Heng-Huan Lee,[...]. Clin Cancer Res 2017
6
DNA Damage and Repair Biomarkers of Immunotherapy Response.
Kent W Mouw, Michael S Goldberg, Panagiotis A Konstantinopoulos, Alan D D'Andrea. Cancer Discov 2017
Kent W Mouw, Michael S Goldberg, Panagiotis A Konstantinopoulos, Alan D D'Andrea. Cancer Discov 2017
6
Prevalence of Homologous Recombination-Related Gene Mutations Across Multiple Cancer Types.
Arielle L Heeke, Michael J Pishvaian, Filipa Lynce, Joanne Xiu, Jonathan R Brody, Wang-Juh Chen, Tabari M Baker, John L Marshall, Claudine Isaacs. JCO Precis Oncol 2018
Arielle L Heeke, Michael J Pishvaian, Filipa Lynce, Joanne Xiu, Jonathan R Brody, Wang-Juh Chen, Tabari M Baker, John L Marshall, Claudine Isaacs. JCO Precis Oncol 2018
6
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.