Meng-Lin Li, Xi-Quan Hu, Feng Li, Wen-Jun Gao. Prog Neuropsychopharmacol Biol Psychiatry 2015
Times Cited: 40
Times Cited: 40
Times Cited
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Sandeep T Patil, Lu Zhang, Ferenc Martenyi, Stephen L Lowe, Kimberley A Jackson, Boris V Andreev, Alla S Avedisova, Leonid M Bardenstein, Issak Y Gurovich, Margarita A Morozova,[...]. Nat Med 2007
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Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats.
B Moghaddam, B W Adams. Science 1998
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A multicenter, inpatient, phase 2, double-blind, placebo-controlled dose-ranging study of LY2140023 monohydrate in patients with DSM-IV schizophrenia.
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Distribution of metabotropic glutamate receptor mGluR3 in the mouse CNS: differential location relative to pre- and postsynaptic sites.
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Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia.
P Jeffrey Conn, Craig W Lindsley, Carrie K Jones. Trends Pharmacol Sci 2009
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Metabotropic glutamate receptors: physiology, pharmacology, and disease.
Colleen M Niswender, P Jeffrey Conn. Annu Rev Pharmacol Toxicol 2010
Colleen M Niswender, P Jeffrey Conn. Annu Rev Pharmacol Toxicol 2010
22
Group II metabotropic glutamate receptor agonist LY379268 regulates AMPA receptor trafficking in prefrontal cortical neurons.
Min-Juan Wang, Yan-Chun Li, Melissa A Snyder, Huaixing Wang, Feng Li, Wen-Jun Gao. PLoS One 2013
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Regulation of neurotransmitter release by metabotropic glutamate receptors.
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Group II metabotropic glutamate receptor agonists and positive allosteric modulators as novel treatments for schizophrenia.
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Positive allosteric modulators of metabotropic glutamate 2 receptors in schizophrenia treatment.
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Recent advances in the phencyclidine model of schizophrenia.
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LY-2140023, a prodrug of the group II metabotropic glutamate receptor agonist LY-404039 for the potential treatment of schizophrenia.
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Group II metabotropic glutamate receptor agonist ameliorates MK801-induced dysfunction of NMDA receptors via the Akt/GSK-3β pathway in adult rat prefrontal cortex.
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CNS distribution of metabotropic glutamate 2 and 3 receptors: transgenic mice and [³H]LY459477 autoradiography.
Rebecca A Wright, Bryan G Johnson, Ce Zhang, Craig Salhoff, Ann E Kingston, David O Calligaro, James A Monn, Darryle D Schoepp, Gerard J Marek. Neuropharmacology 2013
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15
Effects of a metabotropic glutamate receptor group II agonist LY354740 in animal models of positive schizophrenia symptoms and cognition.
Chantal Schlumberger, Daniela Schäfer, Caroline Barberi, Lorenzo Morè, Jens Nagel, Małgorzata Pietraszek, Werner J Schmidt, Wojciech Danysz. Behav Pharmacol 2009
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15
A long-term, phase 2, multicenter, randomized, open-label, comparative safety study of pomaglumetad methionil (LY2140023 monohydrate) versus atypical antipsychotic standard of care in patients with schizophrenia.
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David H Adams, Bruce J Kinon, Simin Baygani, Brian A Millen, Isabella Velona, Sara Kollack-Walker, David P Walling. BMC Psychiatry 2013
15
Pomaglumetad methionil: no significant difference as an adjunctive treatment for patients with prominent negative symptoms of schizophrenia compared to placebo.
Virginia L Stauffer, Brian A Millen, Scott Andersen, Bruce J Kinon, Lisa Lagrandeur, J P Lindenmayer, Juan Carlos Gomez. Schizophr Res 2013
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A Double-Blind, Placebo-Controlled Comparator Study of LY2140023 monohydrate in patients with schizophrenia.
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15
Metabotropic glutamate receptors: from the workbench to the bedside.
F Nicoletti, J Bockaert, G L Collingridge, P J Conn, F Ferraguti, D D Schoepp, J T Wroblewski, J P Pin. Neuropharmacology 2011
F Nicoletti, J Bockaert, G L Collingridge, P J Conn, F Ferraguti, D D Schoepp, J T Wroblewski, J P Pin. Neuropharmacology 2011
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Group II Metabotropic Glutamate Receptors as Targets for Novel Antipsychotic Drugs.
Carolina Muguruza, J Javier Meana, Luis F Callado. Front Pharmacol 2016
Carolina Muguruza, J Javier Meana, Luis F Callado. Front Pharmacol 2016
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Targeting metabotropic glutamate receptors for novel treatments of schizophrenia.
James Maksymetz, Sean P Moran, P Jeffrey Conn. Mol Brain 2017
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15
The mGlu2 but not the mGlu3 receptor mediates the actions of the mGluR2/3 agonist, LY379268, in mouse models predictive of antipsychotic activity.
M L Woolley, D J Pemberton, S Bate, C Corti, D N C Jones. Psychopharmacology (Berl) 2008
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Treatments for schizophrenia: a critical review of pharmacology and mechanisms of action of antipsychotic drugs.
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12
Pomaglumetad Methionil (LY2140023 Monohydrate) and Aripiprazole in Patients with Schizophrenia: A Phase 3, Multicenter, Double-Blind Comparison.
David H Adams, Lu Zhang, Brian A Millen, Bruce J Kinon, Juan-Carlos Gomez. Schizophr Res Treatment 2014
David H Adams, Lu Zhang, Brian A Millen, Bruce J Kinon, Juan-Carlos Gomez. Schizophr Res Treatment 2014
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The metabotropic glutamate receptors, mGluR2 and mGluR3, show unique postsynaptic, presynaptic and glial localizations.
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Evidence for the role of metabotropic glutamate (mGlu)2 not mGlu3 receptors in the preclinical antipsychotic pharmacology of the mGlu2/3 receptor agonist (-)-(1R,4S,5S,6S)-4-amino-2-sulfonylbicyclo[3.1.0]hexane-4,6-dicarboxylic acid (LY404039).
Matthew J Fell, Kjell A Svensson, Bryan G Johnson, Darryle D Schoepp. J Pharmacol Exp Ther 2008
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Pharmacological agents acting at subtypes of metabotropic glutamate receptors.
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A selective allosteric potentiator of metabotropic glutamate (mGlu) 2 receptors has effects similar to an orthosteric mGlu2/3 receptor agonist in mouse models predictive of antipsychotic activity.
Ruggero Galici, Nicholas G Echemendia, Alice L Rodriguez, P Jeffrey Conn. J Pharmacol Exp Ther 2005
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12
Group II metabotropic glutamate receptors enhance NMDA receptor currents via a protein kinase C-dependent mechanism in pyramidal neurones of rat prefrontal cortex.
Joanna P Tyszkiewicz, Zhenglin Gu, Xun Wang, Xiang Cai, Zhen Yan. J Physiol 2004
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The dopamine hypothesis of schizophrenia: version III--the final common pathway.
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Oliver D Howes, Shitij Kapur. Schizophr Bull 2009
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NMDA hypofunction as a convergence point for progression and symptoms of schizophrenia.
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12
Pharmacological and pharmacokinetic properties of JNJ-40411813, a positive allosteric modulator of the mGlu2 receptor.
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Glutamate and schizophrenia: beyond the dopamine hypothesis.
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Differential expression of metabotropic glutamate receptors 2 and 3 in schizophrenia: a mechanism for antipsychotic drug action?
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Identification of a serotonin/glutamate receptor complex implicated in psychosis.
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12
Preliminary evidence of attenuation of the disruptive effects of the NMDA glutamate receptor antagonist, ketamine, on working memory by pretreatment with the group II metabotropic glutamate receptor agonist, LY354740, in healthy human subjects.
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John H Krystal, Walid Abi-Saab, Edward Perry, D Cyril D'Souza, Nianjin Liu, Ralitza Gueorguieva, Lisa McDougall, Tracy Hunsberger, Aysenil Belger, Louise Levine,[...]. Psychopharmacology (Berl) 2005
12
From revolution to evolution: the glutamate hypothesis of schizophrenia and its implication for treatment.
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Selective actions of novel allosteric modulators reveal functional heteromers of metabotropic glutamate receptors in the CNS.
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Pharmacology and functions of metabotropic glutamate receptors.
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Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.
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AZD8529, a positive allosteric modulator at the mGluR2 receptor, does not improve symptoms in schizophrenia: A proof of principle study.
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12
Neuroprotective effects of LY379268, a selective mGlu2/3 receptor agonist: investigations into possible mechanism of action in vivo.
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10
Ketamine administration during the second postnatal week induces enduring schizophrenia-like behavioral symptoms and reduces parvalbumin expression in the medial prefrontal cortex of adult mice.
Vivek Jeevakumar, Christopher Driskill, Alyssa Paine, Millad Sobhanian, Haris Vakil, Brett Morris, Jeremiah Ramos, Sven Kroener. Behav Brain Res 2015
Vivek Jeevakumar, Christopher Driskill, Alyssa Paine, Millad Sobhanian, Haris Vakil, Brett Morris, Jeremiah Ramos, Sven Kroener. Behav Brain Res 2015
10
A neurobiological hypothesis for the classification of schizophrenia: type A (hyperdopaminergic) and type B (normodopaminergic).
Oliver D Howes, Shitij Kapur. Br J Psychiatry 2014
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10
Group II metabotropic glutamate receptors modify N-methyl-D-aspartate receptors via Src kinase.
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Catherine Trepanier, Gang Lei, Yu-Feng Xie, John F MacDonald. Sci Rep 2013
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Pharmacological manipulation of mGlu2 receptors influences cognitive performance in the rodent.
Guy A Higgins, Theresa M Ballard, James N C Kew, J Grayson Richards, John A Kemp, Geo Adam, Thomas Woltering, Shigetada Nakanishi, Vincent Mutel. Neuropharmacology 2004
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10
Pharmacokinetic and pharmacodynamic characterisation of JNJ-40411813, a positive allosteric modulator of mGluR2, in two randomised, double-blind phase-I studies.
Hiba Salih, Ion Anghelescu, Iva Kezic, Vikash Sinha, Eef Hoeben, Luc Van Nueten, Heidi De Smedt, Peter De Boer. J Psychopharmacol 2015
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11
Discovery of 1-butyl-3-chloro-4-(4-phenyl-1-piperidinyl)-(1H)-pyridone (JNJ-40411813): a novel positive allosteric modulator of the metabotropic glutamate 2 receptor.
José María Cid, Gary Tresadern, Guillaume Duvey, Robert Lütjens, Terry Finn, Jean-Philippe Rocher, Sonia Poli, Juan Antonio Vega, Ana Isabel de Lucas, Encarnación Matesanz,[...]. J Med Chem 2014
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10
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.