A citation-based method for searching scientific literature

Yoshifumi Saisho. Endocr Metab Immune Disord Drug Targets 2015
Times Cited: 231







List of co-cited articles
773 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status.
Amy R Cameron, Vicky L Morrison, Daniel Levin, Mohapradeep Mohan, Calum Forteath, Craig Beall, Alison D McNeilly, David J K Balfour, Terhi Savinko, Aaron K F Wong,[...]. Circ Res 2016
290
18

The mechanisms of action of metformin.
Graham Rena, D Grahame Hardie, Ewan R Pearson. Diabetologia 2017
751
17

Role of AMP-activated protein kinase in mechanism of metformin action.
G Zhou, R Myers, Y Li, Y Chen, X Shen, J Fenyk-Melody, M Wu, J Ventre, T Doebber, N Fujii,[...]. J Clin Invest 2001
14

Metformin improves healthspan and lifespan in mice.
Alejandro Martin-Montalvo, Evi M Mercken, Sarah J Mitchell, Hector H Palacios, Patricia L Mote, Morten Scheibye-Knudsen, Ana P Gomes, Theresa M Ward, Robin K Minor, Marie-José Blouin,[...]. Nat Commun 2013
733
13


Metformin as a Tool to Target Aging.
Nir Barzilai, Jill P Crandall, Stephen B Kritchevsky, Mark A Espeland. Cell Metab 2016
464
11

Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism.
Filipe Cabreiro, Catherine Au, Kit-Yi Leung, Nuria Vergara-Irigaray, Helena M Cochemé, Tahereh Noori, David Weinkove, Eugene Schuster, Nicholas D E Greene, David Gems. Cell 2013
532
11


Biguanide metformin acts on tau phosphorylation via mTOR/protein phosphatase 2A (PP2A) signaling.
Eva Kickstein, Sybille Krauss, Paul Thornhill, Désirée Rutschow, Raphael Zeller, John Sharkey, Ritchie Williamson, Melanie Fuchs, Andrea Köhler, Hartmut Glossmann,[...]. Proc Natl Acad Sci U S A 2010
279
11


10-year follow-up of intensive glucose control in type 2 diabetes.
Rury R Holman, Sanjoy K Paul, M Angelyn Bethel, David R Matthews, H Andrew W Neil. N Engl J Med 2008
11

Metformin: from mechanisms of action to therapies.
Marc Foretz, Bruno Guigas, Luc Bertrand, Michael Pollak, Benoit Viollet. Cell Metab 2014
661
10

Metformin inhibits the senescence-associated secretory phenotype by interfering with IKK/NF-κB activation.
Olga Moiseeva, Xavier Deschênes-Simard, Emmanuelle St-Germain, Sebastian Igelmann, Geneviève Huot, Alexandra E Cadar, Véronique Bourdeau, Michael N Pollak, Gerardo Ferbeyre. Aging Cell 2013
266
10


Long-term metformin usage and cognitive function among older adults with diabetes.
Tze Pin Ng, Liang Feng, Keng Bee Yap, Tih Shih Lee, Chay Hoon Tan, Bengt Winblad. J Alzheimers Dis 2014
179
9

Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase.
Anila K Madiraju, Derek M Erion, Yasmeen Rahimi, Xian-Man Zhang, Demetrios T Braddock, Ronald A Albright, Brett J Prigaro, John L Wood, Sanjay Bhanot, Michael J MacDonald,[...]. Nature 2014
708
9

Sirtuin 1-mediated cellular metabolic memory of high glucose via the LKB1/AMPK/ROS pathway and therapeutic effects of metformin.
Zhi Zheng, Haibing Chen, Jun Li, Tao Li, Bingqing Zheng, Ying Zheng, Huiyi Jin, Ying He, Qing Gu, Xun Xu. Diabetes 2012
177
8

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state.
Marc Foretz, Sophie Hébrard, Jocelyne Leclerc, Elham Zarrinpashneh, Maud Soty, Gilles Mithieux, Kei Sakamoto, Fabrizio Andreelli, Benoit Viollet. J Clin Invest 2010
835
8

Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria.
Hannah R Bridges, Andrew J Y Jones, Michael N Pollak, Judy Hirst. Biochem J 2014
384
8

Metformin: historical overview.
Clifford J Bailey. Diabetologia 2017
291
8

Metformin Down-regulates TNF-α Secretion via Suppression of Scavenger Receptors in Macrophages.
Bobae Hyun, Seulmee Shin, Aeri Lee, Sungwon Lee, Youngcheon Song, Nam-Joo Ha, Kyung-Hea Cho, Kyungjae Kim. Immune Netw 2013
64
12

Metformin action: concentrations matter.
Ling He, Fredric E Wondisford. Cell Metab 2015
239
8

Cellular and molecular mechanisms of metformin: an overview.
Benoit Viollet, Bruno Guigas, Nieves Sanz Garcia, Jocelyne Leclerc, Marc Foretz, Fabrizio Andreelli. Clin Sci (Lond) 2012
7

Metformin may produce antidepressant effects through improvement of cognitive function among depressed patients with diabetes mellitus.
Min Guo, Jia Mi, Qiu-Ming Jiang, Jin-Mei Xu, Ying-Ying Tang, Geng Tian, Bin Wang. Clin Exp Pharmacol Physiol 2014
111
7

Metformin promotes lifespan through mitohormesis via the peroxiredoxin PRDX-2.
Wouter De Haes, Lotte Frooninckx, Roel Van Assche, Arne Smolders, Geert Depuydt, Johan Billen, Bart P Braeckman, Liliane Schoofs, Liesbet Temmerman. Proc Natl Acad Sci U S A 2014
190
7

Can people with type 2 diabetes live longer than those without? A comparison of mortality in people initiated with metformin or sulphonylurea monotherapy and matched, non-diabetic controls.
C A Bannister, S E Holden, S Jenkins-Jones, C Ll Morgan, J P Halcox, G Schernthaner, J Mukherjee, C J Currie. Diabetes Obes Metab 2014
178
7

The Therapeutic Potential of Metformin in Neurodegenerative Diseases.
Carola Rotermund, Gerrit Machetanz, Julia C Fitzgerald. Front Endocrinol (Lausanne) 2018
124
7

Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota.
Kristoffer Forslund, Falk Hildebrand, Trine Nielsen, Gwen Falony, Emmanuelle Le Chatelier, Shinichi Sunagawa, Edi Prifti, Sara Vieira-Silva, Valborg Gudmundsdottir, Helle K Pedersen,[...]. Nature 2015
974
7

Metformin and the gastrointestinal tract.
Laura J McCreight, Clifford J Bailey, Ewan R Pearson. Diabetologia 2016
293
7

Metformin Treatment Was Associated with Decreased Mortality in COVID-19 Patients with Diabetes in a Retrospective Analysis.
Pan Luo, Lin Qiu, Yi Liu, Xiu-Lan Liu, Jian-Ling Zheng, Hui-Ying Xue, Wen-Hua Liu, Dong Liu, Juan Li. Am J Trop Med Hyg 2020
133
7


Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin.
William C Knowler, Elizabeth Barrett-Connor, Sarah E Fowler, Richard F Hamman, John M Lachin, Elizabeth A Walker, David M Nathan. N Engl J Med 2002
6

Improvement of cardiac functions by chronic metformin treatment is associated with enhanced cardiac autophagy in diabetic OVE26 mice.
Zhonglin Xie, Kai Lau, Bonnie Eby, Pedro Lozano, Chaoyong He, Becky Pennington, Hongliang Li, Shradha Rathi, Yunzhou Dong, Rong Tian,[...]. Diabetes 2011
346
6

Long-term effects of metformin on metabolism and microvascular and macrovascular disease in patients with type 2 diabetes mellitus.
Adriaan Kooy, Jolien de Jager, Philippe Lehert, Daniël Bets, Michiel G Wulffelé, Ab J M Donker, Coen D A Stehouwer. Arch Intern Med 2009
257
6

Metformin limits ceramide-induced senescence in C2C12 myoblasts.
Kavita S Jadhav, Cory M Dungan, David L Williamson. Mech Ageing Dev 2013
38
15

Metformin inhibits mitochondrial adaptations to aerobic exercise training in older adults.
Adam R Konopka, Jaime L Laurin, Hayden M Schoenberg, Justin J Reid, William M Castor, Christopher A Wolff, Robert V Musci, Oscar D Safairad, Melissa A Linden, Laurie M Biela,[...]. Aging Cell 2019
64
9

Type 2 diabetes and antidiabetic medications in relation to dementia diagnosis.
Chin Cheng, Ching-Heng Lin, Yi-Wen Tsai, Chia-Jui Tsai, Po-Han Chou, Tsuo-Hung Lan. J Gerontol A Biol Sci Med Sci 2014
85
7

Effects of the Insulin Sensitizer Metformin in Alzheimer Disease: Pilot Data From a Randomized Placebo-controlled Crossover Study.
Aaron M Koenig, Dawn Mechanic-Hamilton, Sharon X Xie, Martha F Combs, Anne R Cappola, Long Xie, John A Detre, David A Wolk, Steven E Arnold. Alzheimer Dis Assoc Disord 2017
134
6

Metformin Acts on Two Different Molecular Pathways to Enhance Adult Neural Precursor Proliferation/Self-Renewal and Differentiation.
Michael Fatt, Karolynn Hsu, Ling He, Fredric Wondisford, Freda D Miller, David R Kaplan, Jing Wang. Stem Cell Reports 2015
67
8

Metformin and reduced risk of cancer in diabetic patients.
Josie M M Evans, Louise A Donnelly, Alistair M Emslie-Smith, Dario R Alessi, Andrew D Morris. BMJ 2005
6


Anti-inflammatory mechanism of metformin and its effects in intestinal inflammation and colitis-associated colon cancer.
Seong-Joon Koh, Jung Mogg Kim, In-Kyoung Kim, Su Hyuk Ko, Joo Sung Kim. J Gastroenterol Hepatol 2014
108
6

Effects of metformin versus glipizide on cardiovascular outcomes in patients with type 2 diabetes and coronary artery disease.
Jie Hong, Yifei Zhang, Shenghan Lai, Ankang Lv, Qing Su, Yan Dong, Zhiguang Zhou, Weili Tang, Jiajun Zhao, Lianqun Cui,[...]. Diabetes Care 2013
213
6

Repurposing metformin for the prevention of cancer and cancer recurrence.
Brandy M Heckman-Stoddard, Andrea DeCensi, Vikrant V Sahasrabuddhe, Leslie G Ford. Diabetologia 2017
130
6

Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner.
Adem Kalender, Anand Selvaraj, So Young Kim, Pawan Gulati, Sophie Brûlé, Benoit Viollet, Bruce E Kemp, Nabeel Bardeesy, Patrick Dennis, John J Schlager,[...]. Cell Metab 2010
587
6

Metformin as an Anticancer Agent.
Ales Vancura, Pengli Bu, Madhura Bhagwat, Joey Zeng, Ivana Vancurova. Trends Pharmacol Sci 2018
110
6


Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.
M Y El-Mir, V Nogueira, E Fontaine, N Avéret, M Rigoulet, X Leverve. J Biol Chem 2000
955
6

Metformin pathways: pharmacokinetics and pharmacodynamics.
Li Gong, Srijib Goswami, Kathleen M Giacomini, Russ B Altman, Teri E Klein. Pharmacogenet Genomics 2012
243
6

Metformin inhibits monocyte-to-macrophage differentiation via AMPK-mediated inhibition of STAT3 activation: potential role in atherosclerosis.
Sathish Babu Vasamsetti, Santosh Karnewar, Anantha Koteswararao Kanugula, Avinash Raj Thatipalli, Jerald Mahesh Kumar, Srigiridhar Kotamraju. Diabetes 2015
211
6


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.