Galen W Heyne, Cal G Melberg, Padydeh Doroodchi, Kia F Parins, Henry W Kietzman, Joshua L Everson, Lydia J Ansen-Wilson, Robert J Lipinski. PLoS One 2015
Times Cited: 42
Times Cited: 42
Times Cited
Times Co-cited
Similarity
Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function.
C Chiang, Y Litingtung, E Lee, K E Young, J L Corden, H Westphal, P A Beachy. Nature 1996
C Chiang, Y Litingtung, E Lee, K E Young, J L Corden, H Westphal, P A Beachy. Nature 1996
38
Cleft lip and palate results from Hedgehog signaling antagonism in the mouse: Phenotypic characterization and clinical implications.
Robert J Lipinski, Chihwa Song, Kathleen K Sulik, Joshua L Everson, Jerry J Gipp, Dong Yan, Wade Bushman, Ian J Rowland. Birth Defects Res A Clin Mol Teratol 2010
Robert J Lipinski, Chihwa Song, Kathleen K Sulik, Joshua L Everson, Jerry J Gipp, Dong Yan, Wade Bushman, Ian J Rowland. Birth Defects Res A Clin Mol Teratol 2010
33
Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia.
Juhee Jeong, Junhao Mao, Toyoaki Tenzen, Andreas H Kottmann, Andrew P McMahon. Genes Dev 2004
Juhee Jeong, Junhao Mao, Toyoaki Tenzen, Andreas H Kottmann, Andrew P McMahon. Genes Dev 2004
33
The teratogenic effects of prenatal ethanol exposure are exacerbated by Sonic Hedgehog or GLI2 haploinsufficiency in the mouse.
Henry W Kietzman, Joshua L Everson, Kathleen K Sulik, Robert J Lipinski. PLoS One 2014
Henry W Kietzman, Joshua L Everson, Kathleen K Sulik, Robert J Lipinski. PLoS One 2014
30
Cdon mutation and fetal ethanol exposure synergize to produce midline signaling defects and holoprosencephaly spectrum disorders in mice.
Mingi Hong, Robert S Krauss. PLoS Genet 2012
Mingi Hong, Robert S Krauss. PLoS Genet 2012
28
Loss-of-function mutations in the human GLI2 gene are associated with pituitary anomalies and holoprosencephaly-like features.
Erich Roessler, Yang-Zhu Du, Jose L Mullor, Esther Casas, William P Allen, Gabriele Gillessen-Kaesbach, Elizabeth R Roeder, Jeffrey E Ming, Ariel Ruiz i Altaba, Maximilian Muenke. Proc Natl Acad Sci U S A 2003
Erich Roessler, Yang-Zhu Du, Jose L Mullor, Esther Casas, William P Allen, Gabriele Gillessen-Kaesbach, Elizabeth R Roeder, Jeffrey E Ming, Ariel Ruiz i Altaba, Maximilian Muenke. Proc Natl Acad Sci U S A 2003
28
Gene-Environment Interactions and the Etiology of Birth Defects.
Robert S Krauss, Mingi Hong. Curr Top Dev Biol 2016
Robert S Krauss, Mingi Hong. Curr Top Dev Biol 2016
29
Gli2 gene-environment interactions contribute to the etiological complexity of holoprosencephaly: evidence from a mouse model.
Galen W Heyne, Joshua L Everson, Lydia J Ansen-Wilson, Cal G Melberg, Dustin M Fink, Kia F Parins, Padydeh Doroodchi, Caden M Ulschmid, Robert J Lipinski. Dis Model Mech 2016
Galen W Heyne, Joshua L Everson, Lydia J Ansen-Wilson, Cal G Melberg, Dustin M Fink, Kia F Parins, Padydeh Doroodchi, Caden M Ulschmid, Robert J Lipinski. Dis Model Mech 2016
37
The molecular genetics of holoprosencephaly.
Erich Roessler, Maximilian Muenke. Am J Med Genet C Semin Med Genet 2010
Erich Roessler, Maximilian Muenke. Am J Med Genet C Semin Med Genet 2010
26
Mutations in the human Sonic Hedgehog gene cause holoprosencephaly.
E Roessler, E Belloni, K Gaudenz, P Jay, P Berta, S W Scherer, L C Tsui, M Muenke. Nat Genet 1996
E Roessler, E Belloni, K Gaudenz, P Jay, P Berta, S W Scherer, L C Tsui, M Muenke. Nat Genet 1996
23
A Simple and Reliable Method for Early Pregnancy Detection in Inbred Mice.
Galen W Heyne, Erin H Plisch, Cal G Melberg, Eric P Sandgren, Jody A Peter, Robert J Lipinski. J Am Assoc Lab Anim Sci 2015
Galen W Heyne, Erin H Plisch, Cal G Melberg, Eric P Sandgren, Jody A Peter, Robert J Lipinski. J Am Assoc Lab Anim Sci 2015
23
Temporal perturbations in sonic hedgehog signaling elicit the spectrum of holoprosencephaly phenotypes.
Dwight Cordero, Ralph Marcucio, Diane Hu, William Gaffield, Minal Tapadia, Jill A Helms. J Clin Invest 2004
Dwight Cordero, Ralph Marcucio, Diane Hu, William Gaffield, Minal Tapadia, Jill A Helms. J Clin Invest 2004
21
Sonic hedgehog signaling regulates reciprocal epithelial-mesenchymal interactions controlling palatal outgrowth.
Yu Lan, Rulang Jiang. Development 2009
Yu Lan, Rulang Jiang. Development 2009
21
Analysis of genotype-phenotype correlations in human holoprosencephaly.
Benjamin D Solomon, Sandra Mercier, Jorge I Vélez, Daniel E Pineda-Alvarez, Adrian Wyllie, Nan Zhou, Christèle Dubourg, Veronique David, Sylvie Odent, Erich Roessler,[...]. Am J Med Genet C Semin Med Genet 2010
Benjamin D Solomon, Sandra Mercier, Jorge I Vélez, Daniel E Pineda-Alvarez, Adrian Wyllie, Nan Zhou, Christèle Dubourg, Veronique David, Sylvie Odent, Erich Roessler,[...]. Am J Med Genet C Semin Med Genet 2010
21
Sonic hedgehog regulation of Foxf2 promotes cranial neural crest mesenchyme proliferation and is disrupted in cleft lip morphogenesis.
Joshua L Everson, Dustin M Fink, Joon Won Yoon, Elizabeth J Leslie, Henry W Kietzman, Lydia J Ansen-Wilson, Hannah M Chung, David O Walterhouse, Mary L Marazita, Robert J Lipinski. Development 2017
Joshua L Everson, Dustin M Fink, Joon Won Yoon, Elizabeth J Leslie, Henry W Kietzman, Lydia J Ansen-Wilson, Hannah M Chung, David O Walterhouse, Mary L Marazita, Robert J Lipinski. Development 2017
21
Holoprosencephaly in the genomics era.
Erich Roessler, Ping Hu, Maximilian Muenke. Am J Med Genet C Semin Med Genet 2018
Erich Roessler, Ping Hu, Maximilian Muenke. Am J Med Genet C Semin Med Genet 2018
33
Molecular interactions coordinating the development of the forebrain and face.
Ralph S Marcucio, Dwight R Cordero, Diane Hu, Jill A Helms. Dev Biol 2005
Ralph S Marcucio, Dwight R Cordero, Diane Hu, Jill A Helms. Dev Biol 2005
19
Rescue of holoprosencephaly in fetal alcohol-exposed Cdon mutant mice by reduced gene dosage of Ptch1.
Mingi Hong, Robert S Krauss. PLoS One 2013
Mingi Hong, Robert S Krauss. PLoS One 2013
42
Small molecule modulation of Smoothened activity.
James K Chen, Jussi Taipale, Keith E Young, Tapan Maiti, Philip A Beachy. Proc Natl Acad Sci U S A 2002
James K Chen, Jussi Taipale, Keith E Young, Tapan Maiti, Philip A Beachy. Proc Natl Acad Sci U S A 2002
19
Genotypic and phenotypic analysis of 396 individuals with mutations in Sonic Hedgehog.
Benjamin D Solomon, Kelly A Bear, Adrian Wyllie, Amelia A Keaton, Christele Dubourg, Veronique David, Sandra Mercier, Sylvie Odent, Ute Hehr, Aimee Paulussen,[...]. J Med Genet 2012
Benjamin D Solomon, Kelly A Bear, Adrian Wyllie, Amelia A Keaton, Christele Dubourg, Veronique David, Sandra Mercier, Sylvie Odent, Ute Hehr, Aimee Paulussen,[...]. J Med Genet 2012
19
Ethanol itself is a holoprosencephaly-inducing teratogen.
Mingi Hong, Robert S Krauss. PLoS One 2017
Mingi Hong, Robert S Krauss. PLoS One 2017
29
Mutations in CDON, encoding a hedgehog receptor, result in holoprosencephaly and defective interactions with other hedgehog receptors.
Gyu-Un Bae, Sabina Domené, Erich Roessler, Karen Schachter, Jong-Sun Kang, Maximilian Muenke, Robert S Krauss. Am J Hum Genet 2011
Gyu-Un Bae, Sabina Domené, Erich Roessler, Karen Schachter, Jong-Sun Kang, Maximilian Muenke, Robert S Krauss. Am J Hum Genet 2011
16
The role of sonic hedgehog in normal and abnormal craniofacial morphogenesis.
D Hu, J A Helms. Development 1999
D Hu, J A Helms. Development 1999
16
Patched1 regulates hedgehog signaling at the primary cilium.
Rajat Rohatgi, Ljiljana Milenkovic, Matthew P Scott. Science 2007
Rajat Rohatgi, Ljiljana Milenkovic, Matthew P Scott. Science 2007
16
Fetal ethanol exposure activates protein kinase A and impairs Shh expression in prechordal mesendoderm cells in the pathogenesis of holoprosencephaly.
Kazushi Aoto, Yayoi Shikata, Daisuke Higashiyama, Kohei Shiota, Jun Motoyama. Birth Defects Res A Clin Mol Teratol 2008
Kazushi Aoto, Yayoi Shikata, Daisuke Higashiyama, Kohei Shiota, Jun Motoyama. Birth Defects Res A Clin Mol Teratol 2008
16
Sonic hedgehog rescues cranial neural crest from cell death induced by ethanol exposure.
Sara C Ahlgren, Vijaya Thakur, Marianne Bronner-Fraser. Proc Natl Acad Sci U S A 2002
Sara C Ahlgren, Vijaya Thakur, Marianne Bronner-Fraser. Proc Natl Acad Sci U S A 2002
16
Characterization of subtle brain abnormalities in a mouse model of Hedgehog pathway antagonist-induced cleft lip and palate.
Robert J Lipinski, Hunter T Holloway, Shonagh K O'Leary-Moore, Jacob J Ament, Stephen J Pecevich, Gary P Cofer, Francois Budin, Joshua L Everson, G Allan Johnson, Kathleen K Sulik. PLoS One 2014
Robert J Lipinski, Hunter T Holloway, Shonagh K O'Leary-Moore, Jacob J Ament, Stephen J Pecevich, Gary P Cofer, Francois Budin, Joshua L Everson, G Allan Johnson, Kathleen K Sulik. PLoS One 2014
46
The insecticide synergist piperonyl butoxide inhibits hedgehog signaling: assessing chemical risks.
Jiangbo Wang, Jiuyi Lu, Robert A Mook, Min Zhang, Shengli Zhao, Larry S Barak, Jonathan H Freedman, H Kim Lyerly, Wei Chen. Toxicol Sci 2012
Jiangbo Wang, Jiuyi Lu, Robert A Mook, Min Zhang, Shengli Zhao, Larry S Barak, Jonathan H Freedman, H Kim Lyerly, Wei Chen. Toxicol Sci 2012
31
Holoprosencephaly in human embryos: epidemiologic studies of 150 cases.
E Matsunaga, K Shiota. Teratology 1977
E Matsunaga, K Shiota. Teratology 1977
16
Frequency of holoprosencephaly in the International Clearinghouse Birth Defects Surveillance Systems: searching for population variations.
Emanuele Leoncini, Giovanni Baranello, Iêda M Orioli, Göran Annerén, Marian Bakker, Fabrizio Bianchi, Carol Bower, Mark A Canfield, Eduardo E Castilla, Guido Cocchi,[...]. Birth Defects Res A Clin Mol Teratol 2008
Emanuele Leoncini, Giovanni Baranello, Iêda M Orioli, Göran Annerén, Marian Bakker, Fabrizio Bianchi, Carol Bower, Mark A Canfield, Eduardo E Castilla, Guido Cocchi,[...]. Birth Defects Res A Clin Mol Teratol 2008
16
Inhibition of sonic hedgehog signaling in vivo results in craniofacial neural crest cell death.
S C Ahlgren, M Bronner-Fraser. Curr Biol 1999
S C Ahlgren, M Bronner-Fraser. Curr Biol 1999
14
Fetal alcohol exposure impairs Hedgehog cholesterol modification and signaling.
Yin-Xiong Li, Hai-Tao Yang, Marzena Zdanowicz, Jason K Sicklick, Yi Qi, Terese J Camp, Anna Mae Diehl. Lab Invest 2007
Yin-Xiong Li, Hai-Tao Yang, Marzena Zdanowicz, Jason K Sicklick, Yi Qi, Terese J Camp, Anna Mae Diehl. Lab Invest 2007
14
30
The cell surface membrane proteins Cdo and Boc are components and targets of the Hedgehog signaling pathway and feedback network in mice.
Toyoaki Tenzen, Benjamin L Allen, Francesca Cole, Jong-Sun Kang, Robert S Krauss, Andrew P McMahon. Dev Cell 2006
Toyoaki Tenzen, Benjamin L Allen, Francesca Cole, Jong-Sun Kang, Robert S Krauss, Andrew P McMahon. Dev Cell 2006
14
Sonic hedgehog signalling inhibits palatogenesis and arrests tooth development in a mouse model of the nevoid basal cell carcinoma syndrome.
Martyn T Cobourne, Guilherme M Xavier, Michael Depew, Louise Hagan, Jane Sealby, Zoe Webster, Paul T Sharpe. Dev Biol 2009
Martyn T Cobourne, Guilherme M Xavier, Michael Depew, Louise Hagan, Jane Sealby, Zoe Webster, Paul T Sharpe. Dev Biol 2009
14
Cdo functions at multiple points in the Sonic Hedgehog pathway, and Cdo-deficient mice accurately model human holoprosencephaly.
Wei Zhang, Jong-Sun Kang, Francesca Cole, Min-Jeong Yi, Robert S Krauss. Dev Cell 2006
Wei Zhang, Jong-Sun Kang, Francesca Cole, Min-Jeong Yi, Robert S Krauss. Dev Cell 2006
14
Identification and characterization of several dietary alkaloids as weak inhibitors of hedgehog signaling.
Robert J Lipinski, Emelyne Dengler, Mark Kiehn, Richard E Peterson, Wade Bushman. Toxicol Sci 2007
Robert J Lipinski, Emelyne Dengler, Mark Kiehn, Richard E Peterson, Wade Bushman. Toxicol Sci 2007
22
Identification of Hedgehog signaling inhibitors with relevant human exposure by small molecule screening.
Robert J Lipinski, Wade Bushman. Toxicol In Vitro 2010
Robert J Lipinski, Wade Bushman. Toxicol In Vitro 2010
28
Risk factors for non-syndromic holoprosencephaly in the National Birth Defects Prevention Study.
Eric A Miller, Sonja A Rasmussen, Anna Maria Siega-Riz, Jaime L Frías, Margaret A Honein. Am J Med Genet C Semin Med Genet 2010
Eric A Miller, Sonja A Rasmussen, Anna Maria Siega-Riz, Jaime L Frías, Margaret A Honein. Am J Med Genet C Semin Med Genet 2010
14
Non-genetic risk factors for holoprosencephaly.
Candice Y Johnson, Sonja A Rasmussen. Am J Med Genet C Semin Med Genet 2010
Candice Y Johnson, Sonja A Rasmussen. Am J Med Genet C Semin Med Genet 2010
14
Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development.
R Mo, A M Freer, D L Zinyk, M A Crackower, J Michaud, H H Heng, K W Chik, X M Shi, L C Tsui, S H Cheng,[...]. Development 1997
R Mo, A M Freer, D L Zinyk, M A Crackower, J Michaud, H H Heng, K W Chik, X M Shi, L C Tsui, S H Cheng,[...]. Development 1997
11
Sonic hedgehog from pharyngeal arch 1 epithelium is necessary for early mandibular arch cell survival and later cartilage condensation differentiation.
Katherine Kretovich Billmyre, John Klingensmith. Dev Dyn 2015
Katherine Kretovich Billmyre, John Klingensmith. Dev Dyn 2015
15
Microform holoprosencephaly in mice that lack the Ig superfamily member Cdon.
Francesca Cole, Robert S Krauss. Curr Biol 2003
Francesca Cole, Robert S Krauss. Curr Biol 2003
11
The mechanisms of Hedgehog signalling and its roles in development and disease.
James Briscoe, Pascal P Thérond. Nat Rev Mol Cell Biol 2013
James Briscoe, Pascal P Thérond. Nat Rev Mol Cell Biol 2013
11
Boc and Gas1 each form distinct Shh receptor complexes with Ptch1 and are required for Shh-mediated cell proliferation.
Luisa Izzi, Martin Lévesque, Steves Morin, Dominique Laniel, Brian C Wilkes, Frédéric Mille, Robert S Krauss, Andrew P McMahon, Benjamin L Allen, Frédéric Charron. Dev Cell 2011
Luisa Izzi, Martin Lévesque, Steves Morin, Dominique Laniel, Brian C Wilkes, Frédéric Mille, Robert S Krauss, Andrew P McMahon, Benjamin L Allen, Frédéric Charron. Dev Cell 2011
11
Sonic hedgehog participates in craniofacial morphogenesis and is down-regulated by teratogenic doses of retinoic acid.
J A Helms, C H Kim, D Hu, R Minkoff, C Thaller, G Eichele. Dev Biol 1997
J A Helms, C H Kim, D Hu, R Minkoff, C Thaller, G Eichele. Dev Biol 1997
11
Holoprosencephaly: signaling interactions between the brain and the face, the environment and the genes, and the phenotypic variability in animal models and humans.
Anna Petryk, Daniel Graf, Ralph Marcucio. Wiley Interdiscip Rev Dev Biol 2015
Anna Petryk, Daniel Graf, Ralph Marcucio. Wiley Interdiscip Rev Dev Biol 2015
11
11
Vertebrate Smoothened functions at the primary cilium.
Kevin C Corbit, Pia Aanstad, Veena Singla, Andrew R Norman, Didier Y R Stainier, Jeremy F Reiter. Nature 2005
Kevin C Corbit, Pia Aanstad, Veena Singla, Andrew R Norman, Didier Y R Stainier, Jeremy F Reiter. Nature 2005
11
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.