Van Trung Chu, Timm Weber, Benedikt Wefers, Wolfgang Wurst, Sandrine Sander, Klaus Rajewsky, Ralf Kühn. Nat Biotechnol 2015
Times Cited: 711
Times Cited: 711
Times Cited
Times Co-cited
Similarity
A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.
Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier. Science 2012
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Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining.
Takeshi Maruyama, Stephanie K Dougan, Matthias C Truttmann, Angelina M Bilate, Jessica R Ingram, Hidde L Ploegh. Nat Biotechnol 2015
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RNA-guided human genome engineering via Cas9.
Prashant Mali, Luhan Yang, Kevin M Esvelt, John Aach, Marc Guell, James E DiCarlo, Julie E Norville, George M Church. Science 2013
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Multiplex genome engineering using CRISPR/Cas systems.
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Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage.
Alexis C Komor, Yongjoo B Kim, Michael S Packer, John A Zuris, David R Liu. Nature 2016
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Search-and-replace genome editing without double-strand breaks or donor DNA.
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Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.
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Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery.
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Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity.
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Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system.
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High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.
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DNA targeting specificity of RNA-guided Cas9 nucleases.
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Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA.
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In vivo genome editing using Staphylococcus aureus Cas9.
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Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins.
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GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases.
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Pharmacological inhibition of DNA-PK stimulates Cas9-mediated genome editing.
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Efficient precise knockin with a double cut HDR donor after CRISPR/Cas9-mediated double-stranded DNA cleavage.
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A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells.
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Evolved Cas9 variants with broad PAM compatibility and high DNA specificity.
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Genome engineering using the CRISPR-Cas9 system.
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Non-homologous DNA end joining and alternative pathways to double-strand break repair.
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Genome editing with CRISPR-Cas nucleases, base editors, transposases and prime editors.
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In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration.
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CRISPR-engineered T cells in patients with refractory cancer.
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Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9.
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Advances in genome editing through control of DNA repair pathways.
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Base editing: precision chemistry on the genome and transcriptome of living cells.
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CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair.
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Improved Genome Editing Efficiency and Flexibility Using Modified Oligonucleotides with TALEN and CRISPR-Cas9 Nucleases.
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CRISPR-Cas9 fusion to dominant-negative 53BP1 enhances HDR and inhibits NHEJ specifically at Cas9 target sites.
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Predicting the mutations generated by repair of Cas9-induced double-strand breaks.
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Repair of double-strand breaks induced by CRISPR-Cas9 leads to large deletions and complex rearrangements.
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DNA double-strand break repair-pathway choice in somatic mammalian cells.
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Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression.
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High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells.
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Predictable and precise template-free CRISPR editing of pathogenic variants.
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Nuclear domain 'knock-in' screen for the evaluation and identification of small molecule enhancers of CRISPR-based genome editing.
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Genome editing. The new frontier of genome engineering with CRISPR-Cas9.
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A TALE nuclease architecture for efficient genome editing.
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Enrichment of G2/M cell cycle phase in human pluripotent stem cells enhances HDR-mediated gene repair with customizable endonucleases.
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Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9.
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Increasing Cas9-mediated homology-directed repair efficiency through covalent tethering of DNA repair template.
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12
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.