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Times Cited: 1619
Times Cited: 1619
Times Cited
Times Co-cited
Similarity
A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.
Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier. Science 2012
Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier. Science 2012
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Multiplex genome engineering using CRISPR/Cas systems.
Le Cong, F Ann Ran, David Cox, Shuailiang Lin, Robert Barretto, Naomi Habib, Patrick D Hsu, Xuebing Wu, Wenyan Jiang, Luciano A Marraffini,[...]. Science 2013
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RNA-guided human genome engineering via Cas9.
Prashant Mali, Luhan Yang, Kevin M Esvelt, John Aach, Marc Guell, James E DiCarlo, Julie E Norville, George M Church. Science 2013
Prashant Mali, Luhan Yang, Kevin M Esvelt, John Aach, Marc Guell, James E DiCarlo, Julie E Norville, George M Church. Science 2013
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Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage.
Alexis C Komor, Yongjoo B Kim, Michael S Packer, John A Zuris, David R Liu. Nature 2016
Alexis C Komor, Yongjoo B Kim, Michael S Packer, John A Zuris, David R Liu. Nature 2016
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Search-and-replace genome editing without double-strand breaks or donor DNA.
Andrew V Anzalone, Peyton B Randolph, Jessie R Davis, Alexander A Sousa, Luke W Koblan, Jonathan M Levy, Peter J Chen, Christopher Wilson, Gregory A Newby, Aditya Raguram,[...]. Nature 2019
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Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.
Nicole M Gaudelli, Alexis C Komor, Holly A Rees, Michael S Packer, Ahmed H Badran, David I Bryson, David R Liu. Nature 2017
Nicole M Gaudelli, Alexis C Komor, Holly A Rees, Michael S Packer, Ahmed H Badran, David I Bryson, David R Liu. Nature 2017
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Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system.
Bernd Zetsche, Jonathan S Gootenberg, Omar O Abudayyeh, Ian M Slaymaker, Kira S Makarova, Patrick Essletzbichler, Sara E Volz, Julia Joung, John van der Oost, Aviv Regev,[...]. Cell 2015
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In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni.
Eunji Kim, Taeyoung Koo, Sung Wook Park, Daesik Kim, Kyoungmi Kim, Hee-Yeon Cho, Dong Woo Song, Kyu Jun Lee, Min Hee Jung, Seokjoong Kim,[...]. Nat Commun 2017
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Engineered CRISPR-Cas9 nucleases with altered PAM specificities.
Benjamin P Kleinstiver, Michelle S Prew, Shengdar Q Tsai, Ved V Topkar, Nhu T Nguyen, Zongli Zheng, Andrew P W Gonzales, Zhuyun Li, Randall T Peterson, Jing-Ruey Joanna Yeh,[...]. Nature 2015
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Rationally engineered Cas9 nucleases with improved specificity.
Ian M Slaymaker, Linyi Gao, Bernd Zetsche, David A Scott, Winston X Yan, Feng Zhang. Science 2016
Ian M Slaymaker, Linyi Gao, Bernd Zetsche, David A Scott, Winston X Yan, Feng Zhang. Science 2016
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High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.
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Benjamin P Kleinstiver, Vikram Pattanayak, Michelle S Prew, Shengdar Q Tsai, Nhu T Nguyen, Zongli Zheng, J Keith Joung. Nature 2016
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Genome editing with CRISPR-Cas nucleases, base editors, transposases and prime editors.
Andrew V Anzalone, Luke W Koblan, David R Liu. Nat Biotechnol 2020
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Evolved Cas9 variants with broad PAM compatibility and high DNA specificity.
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Enhanced proofreading governs CRISPR-Cas9 targeting accuracy.
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Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression.
Lei S Qi, Matthew H Larson, Luke A Gilbert, Jennifer A Doudna, Jonathan S Weissman, Adam P Arkin, Wendell A Lim. Cell 2013
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DNA targeting specificity of RNA-guided Cas9 nucleases.
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CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes.
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Base editing: precision chemistry on the genome and transcriptome of living cells.
Holly A Rees, David R Liu. Nat Rev Genet 2018
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Engineered CRISPR-Cas9 nuclease with expanded targeting space.
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Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity.
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Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants.
Russell T Walton, Kathleen A Christie, Madelynn N Whittaker, Benjamin P Kleinstiver. Science 2020
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RNA targeting with CRISPR-Cas13.
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GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases.
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CRISPR provides acquired resistance against viruses in prokaryotes.
Rodolphe Barrangou, Christophe Fremaux, Hélène Deveau, Melissa Richards, Patrick Boyaval, Sylvain Moineau, Dennis A Romero, Philippe Horvath. Science 2007
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Directed evolution of CRISPR-Cas9 to increase its specificity.
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Development and applications of CRISPR-Cas9 for genome engineering.
Patrick D Hsu, Eric S Lander, Feng Zhang. Cell 2014
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Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants.
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RNA editing with CRISPR-Cas13.
David B T Cox, Jonathan S Gootenberg, Omar O Abudayyeh, Brian Franklin, Max J Kellner, Julia Joung, Feng Zhang. Science 2017
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Genome engineering using the CRISPR-Cas9 system.
F Ann Ran, Patrick D Hsu, Jason Wright, Vineeta Agarwala, David A Scott, Feng Zhang. Nat Protoc 2013
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CasX enzymes comprise a distinct family of RNA-guided genome editors.
Jun-Jie Liu, Natalia Orlova, Benjamin L Oakes, Enbo Ma, Hannah B Spinner, Katherine L M Baney, Jonathan Chuck, Dan Tan, Gavin J Knott, Lucas B Harrington,[...]. Nature 2019
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14
Genome editing. The new frontier of genome engineering with CRISPR-Cas9.
Jennifer A Doudna, Emmanuelle Charpentier. Science 2014
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14
A highly specific SpCas9 variant is identified by in vivo screening in yeast.
Antonio Casini, Michele Olivieri, Gianluca Petris, Claudia Montagna, Giordano Reginato, Giulia Maule, Francesca Lorenzin, Davide Prandi, Alessandro Romanel, Francesca Demichelis,[...]. Nat Biotechnol 2018
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13
A Compact, High-Accuracy Cas9 with a Dinucleotide PAM for In Vivo Genome Editing.
Alireza Edraki, Aamir Mir, Raed Ibraheim, Ildar Gainetdinov, Yeonsoo Yoon, Chun-Qing Song, Yueying Cao, Judith Gallant, Wen Xue, Jaime A Rivera-Pérez,[...]. Mol Cell 2019
Alireza Edraki, Aamir Mir, Raed Ibraheim, Ildar Gainetdinov, Yeonsoo Yoon, Chun-Qing Song, Yueying Cao, Judith Gallant, Wen Xue, Jaime A Rivera-Pérez,[...]. Mol Cell 2019
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Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis.
Zhonggang Hou, Yan Zhang, Nicholas E Propson, Sara E Howden, Li-Fang Chu, Erik J Sontheimer, James A Thomson. Proc Natl Acad Sci U S A 2013
Zhonggang Hou, Yan Zhang, Nicholas E Propson, Sara E Howden, Li-Fang Chu, Erik J Sontheimer, James A Thomson. Proc Natl Acad Sci U S A 2013
13
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering.
Haoyi Wang, Hui Yang, Chikdu S Shivalila, Meelad M Dawlaty, Albert W Cheng, Feng Zhang, Rudolf Jaenisch. Cell 2013
Haoyi Wang, Hui Yang, Chikdu S Shivalila, Meelad M Dawlaty, Albert W Cheng, Feng Zhang, Rudolf Jaenisch. Cell 2013
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Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria.
Giedrius Gasiunas, Rodolphe Barrangou, Philippe Horvath, Virginijus Siksnys. Proc Natl Acad Sci U S A 2012
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Streptococcus thermophilus CRISPR-Cas9 Systems Enable Specific Editing of the Human Genome.
Maximilian Müller, Ciaran M Lee, Giedrius Gasiunas, Timothy H Davis, Thomas J Cradick, Virginijus Siksnys, Gang Bao, Toni Cathomen, Claudio Mussolino. Mol Ther 2016
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In vivo gene editing in dystrophic mouse muscle and muscle stem cells.
Mohammadsharif Tabebordbar, Kexian Zhu, Jason K W Cheng, Wei Leong Chew, Jeffrey J Widrick, Winston X Yan, Claire Maesner, Elizabeth Y Wu, Ru Xiao, F Ann Ran,[...]. Science 2016
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Permanent alteration of PCSK9 with in vivo CRISPR-Cas9 genome editing.
Qiurong Ding, Alanna Strong, Kevin M Patel, Sze-Ling Ng, Bridget S Gosis, Stephanie N Regan, Chad A Cowan, Daniel J Rader, Kiran Musunuru. Circ Res 2014
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High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells.
Yanfang Fu, Jennifer A Foden, Cyd Khayter, Morgan L Maeder, Deepak Reyon, J Keith Joung, Jeffry D Sander. Nat Biotechnol 2013
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Identification of preexisting adaptive immunity to Cas9 proteins in humans.
Carsten T Charlesworth, Priyanka S Deshpande, Daniel P Dever, Joab Camarena, Viktor T Lemgart, M Kyle Cromer, Christopher A Vakulskas, Michael A Collingwood, Liyang Zhang, Nicole M Bode,[...]. Nat Med 2019
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One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering.
Hui Yang, Haoyi Wang, Chikdu S Shivalila, Albert W Cheng, Linyu Shi, Rudolf Jaenisch. Cell 2013
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Orthogonal Cas9 proteins for RNA-guided gene regulation and editing.
Kevin M Esvelt, Prashant Mali, Jonathan L Braff, Mark Moosburner, Stephanie J Yaung, George M Church. Nat Methods 2013
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In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration.
Keiichiro Suzuki, Yuji Tsunekawa, Reyna Hernandez-Benitez, Jun Wu, Jie Zhu, Euiseok J Kim, Fumiyuki Hatanaka, Mako Yamamoto, Toshikazu Araoka, Zhe Li,[...]. Nature 2016
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11
Crystal structure of Cas9 in complex with guide RNA and target DNA.
Hiroshi Nishimasu, F Ann Ran, Patrick D Hsu, Silvana Konermann, Soraya I Shehata, Naoshi Dohmae, Ryuichiro Ishitani, Feng Zhang, Osamu Nureki. Cell 2014
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C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector.
Omar O Abudayyeh, Jonathan S Gootenberg, Silvana Konermann, Julia Joung, Ian M Slaymaker, David B T Cox, Sergey Shmakov, Kira S Makarova, Ekaterina Semenova, Leonid Minakhin,[...]. Science 2016
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Delivering CRISPR: a review of the challenges and approaches.
Christopher A Lino, Jason C Harper, James P Carney, Jerilyn A Timlin. Drug Deliv 2018
Christopher A Lino, Jason C Harper, James P Carney, Jerilyn A Timlin. Drug Deliv 2018
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A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells.
Christopher A Vakulskas, Daniel P Dever, Garrett R Rettig, Rolf Turk, Ashley M Jacobi, Michael A Collingwood, Nicole M Bode, Matthew S McNeill, Shuqi Yan, Joab Camarena,[...]. Nat Med 2018
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11
Rationally engineered Staphylococcus aureus Cas9 nucleases with high genome-wide specificity.
Yuanyan Tan, Athena H Y Chu, Siyu Bao, Duc Anh Hoang, Firaol Tamiru Kebede, Wenjun Xiong, Mingfang Ji, Jiahai Shi, Zongli Zheng. Proc Natl Acad Sci U S A 2019
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In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.
Christopher E Nelson, Chady H Hakim, David G Ousterout, Pratiksha I Thakore, Eirik A Moreb, Ruth M Castellanos Rivera, Sarina Madhavan, Xiufang Pan, F Ann Ran, Winston X Yan,[...]. Science 2016
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11
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.