Candice E Paulsen, Jean-Paul Armache, Yuan Gao, Yifan Cheng, David Julius. Nature 2015
Times Cited: 348
Times Cited: 348
Times Cited
Times Co-cited
Similarity
Structure of the TRPV1 ion channel determined by electron cryo-microscopy.
Maofu Liao, Erhu Cao, David Julius, Yifan Cheng. Nature 2013
Maofu Liao, Erhu Cao, David Julius, Yifan Cheng. Nature 2013
30
TRP channel activation by reversible covalent modification.
Andrew Hinman, Huai-Hu Chuang, Diana M Bautista, David Julius. Proc Natl Acad Sci U S A 2006
Andrew Hinman, Huai-Hu Chuang, Diana M Bautista, David Julius. Proc Natl Acad Sci U S A 2006
28
TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents.
Diana M Bautista, Sven-Eric Jordt, Tetsuro Nikai, Pamela R Tsuruda, Andrew J Read, Jeannie Poblete, Ebenezer N Yamoah, Allan I Basbaum, David Julius. Cell 2006
Diana M Bautista, Sven-Eric Jordt, Tetsuro Nikai, Pamela R Tsuruda, Andrew J Read, Jeannie Poblete, Ebenezer N Yamoah, Allan I Basbaum, David Julius. Cell 2006
25
Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin.
Michael Bandell, Gina M Story, Sun Wook Hwang, Veena Viswanath, Samer R Eid, Matt J Petrus, Taryn J Earley, Ardem Patapoutian. Neuron 2004
Michael Bandell, Gina M Story, Sun Wook Hwang, Veena Viswanath, Samer R Eid, Matt J Petrus, Taryn J Earley, Ardem Patapoutian. Neuron 2004
25
TRPV1 structures in distinct conformations reveal activation mechanisms.
Erhu Cao, Maofu Liao, Yifan Cheng, David Julius. Nature 2013
Erhu Cao, Maofu Liao, Yifan Cheng, David Julius. Nature 2013
25
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1.
Sven-Eric Jordt, Diana M Bautista, Huai-Hu Chuang, David D McKemy, Peter M Zygmunt, Edward D Högestätt, Ian D Meng, David Julius. Nature 2004
Sven-Eric Jordt, Diana M Bautista, Huai-Hu Chuang, David D McKemy, Peter M Zygmunt, Edward D Högestätt, Ian D Meng, David Julius. Nature 2004
23
Mammalian Transient Receptor Potential TRPA1 Channels: From Structure to Disease.
Karel Talavera, Justyna B Startek, Julio Alvarez-Collazo, Brett Boonen, Yeranddy A Alpizar, Alicia Sanchez, Robbe Naert, Bernd Nilius. Physiol Rev 2020
Karel Talavera, Justyna B Startek, Julio Alvarez-Collazo, Brett Boonen, Yeranddy A Alpizar, Alicia Sanchez, Robbe Naert, Bernd Nilius. Physiol Rev 2020
24
ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures.
Gina M Story, Andrea M Peier, Alison J Reeve, Samer R Eid, Johannes Mosbacher, Todd R Hricik, Taryn J Earley, Anne C Hergarden, David A Andersson, Sun Wook Hwang,[...]. Cell 2003
Gina M Story, Andrea M Peier, Alison J Reeve, Samer R Eid, Johannes Mosbacher, Todd R Hricik, Taryn J Earley, Anne C Hergarden, David A Andersson, Sun Wook Hwang,[...]. Cell 2003
22
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines.
Lindsey J Macpherson, Adrienne E Dubin, Michael J Evans, Felix Marr, Peter G Schultz, Benjamin F Cravatt, Ardem Patapoutian. Nature 2007
Lindsey J Macpherson, Adrienne E Dubin, Michael J Evans, Felix Marr, Peter G Schultz, Benjamin F Cravatt, Ardem Patapoutian. Nature 2007
20
Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel.
Yang Suo, Zilong Wang, Lejla Zubcevic, Allen L Hsu, Qianru He, Mario J Borgnia, Ru-Rong Ji, Seok-Yong Lee. Neuron 2020
Yang Suo, Zilong Wang, Lejla Zubcevic, Allen L Hsu, Qianru He, Mario J Borgnia, Ru-Rong Ji, Seok-Yong Lee. Neuron 2020
51
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action.
Yuan Gao, Erhu Cao, David Julius, Yifan Cheng. Nature 2016
Yuan Gao, Erhu Cao, David Julius, Yifan Cheng. Nature 2016
19
Pungent products from garlic activate the sensory ion channel TRPA1.
Diana M Bautista, Pouya Movahed, Andrew Hinman, Helena E Axelsson, Olov Sterner, Edward D Högestätt, David Julius, Sven-Eric Jordt, Peter M Zygmunt. Proc Natl Acad Sci U S A 2005
Diana M Bautista, Pouya Movahed, Andrew Hinman, Helena E Axelsson, Olov Sterner, Edward D Högestätt, David Julius, Sven-Eric Jordt, Peter M Zygmunt. Proc Natl Acad Sci U S A 2005
17
The capsaicin receptor: a heat-activated ion channel in the pain pathway.
M J Caterina, M A Schumacher, M Tominaga, T A Rosen, J D Levine, D Julius. Nature 1997
M J Caterina, M A Schumacher, M Tominaga, T A Rosen, J D Levine, D Julius. Nature 1997
17
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1.
Marcello Trevisani, Jan Siemens, Serena Materazzi, Diana M Bautista, Romina Nassini, Barbara Campi, Noritaka Imamachi, Eunice Andrè, Riccardo Patacchini, Graeme S Cottrell,[...]. Proc Natl Acad Sci U S A 2007
Marcello Trevisani, Jan Siemens, Serena Materazzi, Diana M Bautista, Romina Nassini, Barbara Campi, Noritaka Imamachi, Eunice Andrè, Riccardo Patacchini, Graeme S Cottrell,[...]. Proc Natl Acad Sci U S A 2007
16
A gain-of-function mutation in TRPA1 causes familial episodic pain syndrome.
Barbara Kremeyer, Francisco Lopera, James J Cox, Aliakmal Momin, Francois Rugiero, Steve Marsh, C Geoffrey Woods, Nicholas G Jones, Kathryn J Paterson, Florence R Fricker,[...]. Neuron 2010
Barbara Kremeyer, Francisco Lopera, James J Cox, Aliakmal Momin, Francois Rugiero, Steve Marsh, C Geoffrey Woods, Nicholas G Jones, Kathryn J Paterson, Florence R Fricker,[...]. Neuron 2010
15
Irritant-evoked activation and calcium modulation of the TRPA1 receptor.
Jianhua Zhao, John V Lin King, Candice E Paulsen, Yifan Cheng, David Julius. Nature 2020
Jianhua Zhao, John V Lin King, Candice E Paulsen, Yifan Cheng, David Julius. Nature 2020
37
Cytoplasmic ankyrin repeats of transient receptor potential A1 (TRPA1) dictate sensitivity to thermal and chemical stimuli.
Julio F Cordero-Morales, Elena O Gracheva, David Julius. Proc Natl Acad Sci U S A 2011
Julio F Cordero-Morales, Elena O Gracheva, David Julius. Proc Natl Acad Sci U S A 2011
14
A structural overview of the ion channels of the TRPM family.
Yihe Huang, Ralf Fliegert, Andreas H Guse, Wei Lü, Juan Du. Cell Calcium 2020
Yihe Huang, Ralf Fliegert, Andreas H Guse, Wei Lü, Juan Du. Cell Calcium 2020
20
Transient receptor potential A1 is a sensory receptor for multiple products of oxidative stress.
David A Andersson, Clive Gentry, Sian Moss, Stuart Bevan. J Neurosci 2008
David A Andersson, Clive Gentry, Sian Moss, Stuart Bevan. J Neurosci 2008
13
TRPA1 mediates formalin-induced pain.
Colleen R McNamara, Josh Mandel-Brehm, Diana M Bautista, Jan Siemens, Kari L Deranian, Michael Zhao, Neil J Hayward, Jayhong A Chong, David Julius, Magdalene M Moran,[...]. Proc Natl Acad Sci U S A 2007
Colleen R McNamara, Josh Mandel-Brehm, Diana M Bautista, Jan Siemens, Kari L Deranian, Michael Zhao, Neil J Hayward, Jayhong A Chong, David Julius, Magdalene M Moran,[...]. Proc Natl Acad Sci U S A 2007
13
TRPA1 as a drug target--promise and challenges.
Jun Chen, David H Hackos. Naunyn Schmiedebergs Arch Pharmacol 2015
Jun Chen, David H Hackos. Naunyn Schmiedebergs Arch Pharmacol 2015
13
Molecular characterization of the Drosophila trp locus: a putative integral membrane protein required for phototransduction.
C Montell, G M Rubin. Neuron 1989
C Montell, G M Rubin. Neuron 1989
13
A TRP channel trio mediates acute noxious heat sensing.
Ine Vandewauw, Katrien De Clercq, Marie Mulier, Katharina Held, Silvia Pinto, Nele Van Ranst, Andrei Segal, Thierry Voet, Rudi Vennekens, Katharina Zimmermann,[...]. Nature 2018
Ine Vandewauw, Katrien De Clercq, Marie Mulier, Katharina Held, Silvia Pinto, Nele Van Ranst, Andrei Segal, Thierry Voet, Rudi Vennekens, Katharina Zimmermann,[...]. Nature 2018
13
Cryo-electron microscopy structure of the TRPV2 ion channel.
Lejla Zubcevic, Mark A Herzik, Ben C Chung, Zhirui Liu, Gabriel C Lander, Seok-Yong Lee. Nat Struct Mol Biol 2016
Lejla Zubcevic, Mark A Herzik, Ben C Chung, Zhirui Liu, Gabriel C Lander, Seok-Yong Lee. Nat Struct Mol Biol 2016
13
TRPA1 channels: molecular sentinels of cellular stress and tissue damage.
Félix Viana. J Physiol 2016
Félix Viana. J Physiol 2016
12
Structure of the human TRPM4 ion channel in a lipid nanodisc.
Henriette E Autzen, Alexander G Myasnikov, Melody G Campbell, Daniel Asarnow, David Julius, Yifan Cheng. Science 2018
Henriette E Autzen, Alexander G Myasnikov, Melody G Campbell, Daniel Asarnow, David Julius, Yifan Cheng. Science 2018
12
Structure of the cold- and menthol-sensing ion channel TRPM8.
Ying Yin, Mengyu Wu, Lejla Zubcevic, William F Borschel, Gabriel C Lander, Seok-Yong Lee. Science 2018
Ying Yin, Mengyu Wu, Lejla Zubcevic, William F Borschel, Gabriel C Lander, Seok-Yong Lee. Science 2018
12
The nociceptor ion channel TRPA1 is potentiated and inactivated by permeating calcium ions.
Yuanyuan Y Wang, Rui B Chang, Hang N Waters, David D McKemy, Emily R Liman. J Biol Chem 2008
Yuanyuan Y Wang, Rui B Chang, Hang N Waters, David D McKemy, Emily R Liman. J Biol Chem 2008
12
Bimodal action of menthol on the transient receptor potential channel TRPA1.
Yuji Karashima, Nils Damann, Jean Prenen, Karel Talavera, Andrei Segal, Thomas Voets, Bernd Nilius. J Neurosci 2007
Yuji Karashima, Nils Damann, Jean Prenen, Karel Talavera, Andrei Segal, Thomas Voets, Bernd Nilius. J Neurosci 2007
12
A Non-covalent Ligand Reveals Biased Agonism of the TRPA1 Ion Channel.
Chang Liu, Rebecca Reese, Simon Vu, Lionel Rougé, Shannon D Shields, Satoko Kakiuchi-Kiyota, Huifen Chen, Kevin Johnson, Yu Patrick Shi, Tania Chernov-Rogan,[...]. Neuron 2021
Chang Liu, Rebecca Reese, Simon Vu, Lionel Rougé, Shannon D Shields, Satoko Kakiuchi-Kiyota, Huifen Chen, Kevin Johnson, Yu Patrick Shi, Tania Chernov-Rogan,[...]. Neuron 2021
57
TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction.
Kelvin Y Kwan, Andrew J Allchorne, Melissa A Vollrath, Adam P Christensen, Duan-Sun Zhang, Clifford J Woolf, David P Corey. Neuron 2006
Kelvin Y Kwan, Andrew J Allchorne, Melissa A Vollrath, Adam P Christensen, Duan-Sun Zhang, Clifford J Woolf, David P Corey. Neuron 2006
11
The transient receptor potential channel TRPA1: from gene to pathophysiology.
Bernd Nilius, Giovanni Appendino, Grzegorz Owsianik. Pflugers Arch 2012
Bernd Nilius, Giovanni Appendino, Grzegorz Owsianik. Pflugers Arch 2012
11
A TRP channel that senses cold stimuli and menthol.
Andrea M Peier, Aziz Moqrich, Anne C Hergarden, Alison J Reeve, David A Andersson, Gina M Story, Taryn J Earley, Ilaria Dragoni, Peter McIntyre, Stuart Bevan,[...]. Cell 2002
Andrea M Peier, Aziz Moqrich, Anne C Hergarden, Alison J Reeve, David A Andersson, Gina M Story, Taryn J Earley, Ilaria Dragoni, Peter McIntyre, Stuart Bevan,[...]. Cell 2002
11
Structure of a TRPM2 channel in complex with Ca2+ explains unique gating regulation.
Zhe Zhang, Balázs Tóth, Andras Szollosi, Jue Chen, László Csanády. Elife 2018
Zhe Zhang, Balázs Tóth, Andras Szollosi, Jue Chen, László Csanády. Elife 2018
12
Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel.
Ying Yin, Son C Le, Allen L Hsu, Mario J Borgnia, Huanghe Yang, Seok-Yong Lee. Science 2019
Ying Yin, Son C Le, Allen L Hsu, Mario J Borgnia, Huanghe Yang, Seok-Yong Lee. Science 2019
11
Crystal structure of the epithelial calcium channel TRPV6.
Kei Saotome, Appu K Singh, Maria V Yelshanskaya, Alexander I Sobolevsky. Nature 2016
Kei Saotome, Appu K Singh, Maria V Yelshanskaya, Alexander I Sobolevsky. Nature 2016
11
Cryo-EM structure of TRPC5 at 2.8-Å resolution reveals unique and conserved structural elements essential for channel function.
Jingjing Duan, Jian Li, Gui-Lan Chen, Yan Ge, Jieyu Liu, Kechen Xie, Xiaogang Peng, Wei Zhou, Jianing Zhong, Yixing Zhang,[...]. Sci Adv 2019
Jingjing Duan, Jian Li, Gui-Lan Chen, Yan Ge, Jieyu Liu, Kechen Xie, Xiaogang Peng, Wei Zhou, Jianing Zhong, Yixing Zhang,[...]. Sci Adv 2019
27
Structure and gating mechanism of the transient receptor potential channel TRPV3.
Appu K Singh, Luke L McGoldrick, Alexander I Sobolevsky. Nat Struct Mol Biol 2018
Appu K Singh, Luke L McGoldrick, Alexander I Sobolevsky. Nat Struct Mol Biol 2018
12
Molecular mechanism of TRPV2 channel modulation by cannabidiol.
Ruth A Pumroy, Amrita Samanta, Yuhang Liu, Taylor Et Hughes, Siyuan Zhao, Yevgen Yudin, Tibor Rohacs, Seungil Han, Vera Y Moiseenkova-Bell. Elife 2019
Ruth A Pumroy, Amrita Samanta, Yuhang Liu, Taylor Et Hughes, Siyuan Zhao, Yevgen Yudin, Tibor Rohacs, Seungil Han, Vera Y Moiseenkova-Bell. Elife 2019
20
An introduction to TRP channels.
I Scott Ramsey, Markus Delling, David E Clapham. Annu Rev Physiol 2006
I Scott Ramsey, Markus Delling, David E Clapham. Annu Rev Physiol 2006
11
The pungency of garlic: activation of TRPA1 and TRPV1 in response to allicin.
Lindsey J Macpherson, Bernhard H Geierstanger, Veena Viswanath, Michael Bandell, Samer R Eid, SunWook Hwang, Ardem Patapoutian. Curr Biol 2005
Lindsey J Macpherson, Bernhard H Geierstanger, Veena Viswanath, Michael Bandell, Samer R Eid, SunWook Hwang, Ardem Patapoutian. Curr Biol 2005
10
Identification of transmembrane domain 5 as a critical molecular determinant of menthol sensitivity in mammalian TRPA1 channels.
Bailong Xiao, Adrienne E Dubin, Badry Bursulaya, Veena Viswanath, Timothy J Jegla, Ardem Patapoutian. J Neurosci 2008
Bailong Xiao, Adrienne E Dubin, Badry Bursulaya, Veena Viswanath, Timothy J Jegla, Ardem Patapoutian. J Neurosci 2008
10
Transient receptor potential channels as drug targets: from the science of basic research to the art of medicine.
Bernd Nilius, Arpad Szallasi. Pharmacol Rev 2014
Bernd Nilius, Arpad Szallasi. Pharmacol Rev 2014
10
Structure of the mouse TRPC4 ion channel.
Jingjing Duan, Jian Li, Bo Zeng, Gui-Lan Chen, Xiaogang Peng, Yixing Zhang, Jianbin Wang, David E Clapham, Zongli Li, Jin Zhang. Nat Commun 2018
Jingjing Duan, Jian Li, Bo Zeng, Gui-Lan Chen, Xiaogang Peng, Yixing Zhang, Jianbin Wang, David E Clapham, Zongli Li, Jin Zhang. Nat Commun 2018
14
Identification of a cold receptor reveals a general role for TRP channels in thermosensation.
David D McKemy, Werner M Neuhausser, David Julius. Nature 2002
David D McKemy, Werner M Neuhausser, David Julius. Nature 2002
10
Opening of the human epithelial calcium channel TRPV6.
Luke L McGoldrick, Appu K Singh, Kei Saotome, Maria V Yelshanskaya, Edward C Twomey, Robert A Grassucci, Alexander I Sobolevsky. Nature 2018
Luke L McGoldrick, Appu K Singh, Kei Saotome, Maria V Yelshanskaya, Edward C Twomey, Robert A Grassucci, Alexander I Sobolevsky. Nature 2018
10
Conformational ensemble of the human TRPV3 ion channel.
Lejla Zubcevic, Mark A Herzik, Mengyu Wu, William F Borschel, Marscha Hirschi, Albert S Song, Gabriel C Lander, Seok-Yong Lee. Nat Commun 2018
Lejla Zubcevic, Mark A Herzik, Mengyu Wu, William F Borschel, Marscha Hirschi, Albert S Song, Gabriel C Lander, Seok-Yong Lee. Nat Commun 2018
15
An ankyrin-like protein with transmembrane domains is specifically lost after oncogenic transformation of human fibroblasts.
D Jaquemar, T Schenker, B Trueb. J Biol Chem 1999
D Jaquemar, T Schenker, B Trueb. J Biol Chem 1999
10
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.