A citation-based method for searching scientific literature


List of co-cited articles
809 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Sirolimus in patients with clinically active systemic lupus erythematosus resistant to, or intolerant of, conventional medications: a single-arm, open-label, phase 1/2 trial.
Zhi-Wei Lai, Ryan Kelly, Thomas Winans, Ivan Marchena, Ashwini Shadakshari, Julie Yu, Maha Dawood, Ricardo Garcia, Hajra Tily, Lisa Francis,[...]. Lancet 2018
144
20

mTOR signaling in growth control and disease.
Mathieu Laplante, David M Sabatini. Cell 2012
14



N-acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: a randomized, double-blind, placebo-controlled trial.
Zhi-Wei Lai, Robert Hanczko, Eduardo Bonilla, Tiffany N Caza, Brandon Clair, Adam Bartos, Gabriella Miklossy, John Jimah, Edward Doherty, Hajra Tily,[...]. Arthritis Rheum 2012
192
11

mTOR Signaling in Growth, Metabolism, and Disease.
Robert A Saxton, David M Sabatini. Cell 2017
10

mTOR is a key modulator of ageing and age-related disease.
Simon C Johnson, Peter S Rabinovitch, Matt Kaeberlein. Nature 2013
891
9

Mitochondrial Dysfunction in the Liver and Antiphospholipid Antibody Production Precede Disease Onset and Respond to Rapamycin in Lupus-Prone Mice.
Zachary Oaks, Thomas Winans, Tiffany Caza, David Fernandez, Yuxin Liu, Steve K Landas, Katalin Banki, Andras Perl. Arthritis Rheumatol 2016
52
17

mTOR: from growth signal integration to cancer, diabetes and ageing.
Roberto Zoncu, Alejo Efeyan, David M Sabatini. Nat Rev Mol Cell Biol 2011
8

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.
Greg M Delgoffe, Kristen N Pollizzi, Adam T Waickman, Emily Heikamp, David J Meyers, Maureen R Horton, Bo Xiao, Paul F Worley, Jonathan D Powell. Nat Immunol 2011
701
8

Normalization of CD4+ T cell metabolism reverses lupus.
Yiming Yin, Seung-Chul Choi, Zhiwei Xu, Daniel J Perry, Howard Seay, Byron P Croker, Eric S Sobel, Todd M Brusko, Laurence Morel. Sci Transl Med 2015
285
8

Mechanistic target of rapamycin activation triggers IL-4 production and necrotic death of double-negative T cells in patients with systemic lupus erythematosus.
Zhi-Wei Lai, Rebecca Borsuk, Ashwini Shadakshari, Jianghong Yu, Maha Dawood, Ricardo Garcia, Lisa Francis, Hajra Tily, Adam Bartos, Stephen V Faraone,[...]. J Immunol 2013
75
9

Metabolism as a Target for Modulation in Autoimmune Diseases.
Nick Huang, Andras Perl. Trends Immunol 2018
49
14

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.
David E Harrison, Randy Strong, Zelton Dave Sharp, James F Nelson, Clinton M Astle, Kevin Flurkey, Nancy L Nadon, J Erby Wilkinson, Krystyna Frenkel, Christy S Carter,[...]. Nature 2009
6

The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment.
Greg M Delgoffe, Thomas P Kole, Yan Zheng, Paul E Zarek, Krystal L Matthews, Bo Xiao, Paul F Worley, Sara C Kozma, Jonathan D Powell. Immunity 2009
774
6

AMPK phosphorylation of raptor mediates a metabolic checkpoint.
Dana M Gwinn, David B Shackelford, Daniel F Egan, Maria M Mihaylova, Annabelle Mery, Debbie S Vasquez, Benjamin E Turk, Reuben J Shaw. Mol Cell 2008
6


Comprehensive metabolome analyses reveal N-acetylcysteine-responsive accumulation of kynurenine in systemic lupus erythematosus: implications for activation of the mechanistic target of rapamycin.
Andras Perl, Robert Hanczko, Zhi-Wei Lai, Zachary Oaks, Ryan Kelly, Rebecca Borsuk, John M Asara, Paul E Phillips. Metabolomics 2015
64
9

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery.
Do-Hyung Kim, D D Sarbassov, Siraj M Ali, Jessie E King, Robert R Latek, Hediye Erdjument-Bromage, Paul Tempst, David M Sabatini. Cell 2002
5


TOR signaling in growth and metabolism.
Stephan Wullschleger, Robbie Loewith, Michael N Hall. Cell 2006
5

mTOR regulates memory CD8 T-cell differentiation.
Koichi Araki, Alexandra P Turner, Virginia Oliva Shaffer, Shivaprakash Gangappa, Susanne A Keller, Martin F Bachmann, Christian P Larsen, Rafi Ahmed. Nature 2009
983
5

The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
5

Activation of a metabolic gene regulatory network downstream of mTOR complex 1.
Katrin Düvel, Jessica L Yecies, Suchithra Menon, Pichai Raman, Alex I Lipovsky, Amanda L Souza, Ellen Triantafellow, Qicheng Ma, Regina Gorski, Stephen Cleaver,[...]. Mol Cell 2010
5

HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells.
Lewis Z Shi, Ruoning Wang, Gonghua Huang, Peter Vogel, Geoffrey Neale, Douglas R Green, Hongbo Chi. J Exp Med 2011
960
5

The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function.
Andrew N Macintyre, Valerie A Gerriets, Amanda G Nichols, Ryan D Michalek, Michael C Rudolph, Divino Deoliveira, Steven M Anderson, E Dale Abel, Benny J Chen, Laura P Hale,[...]. Cell Metab 2014
497
5

A Positive Feedback Loop between Akt and mTORC2 via SIN1 Phosphorylation.
Guang Yang, Danielle S Murashige, Sean J Humphrey, David E James. Cell Rep 2015
153
5


Regulation of T cells by mTOR: the known knowns and the known unknowns.
Kristen N Pollizzi, Jonathan D Powell. Trends Immunol 2015
107
4

Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation.
Linda V Sinclair, Julia Rolf, Elizabeth Emslie, Yun-Bo Shi, Peter M Taylor, Doreen A Cantrell. Nat Immunol 2013
436
4

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB.
Dos D Sarbassov, Siraj M Ali, Shomit Sengupta, Joon-Ho Sheen, Peggy P Hsu, Alex F Bagley, Andrew L Markhard, David M Sabatini. Mol Cell 2006
4

mTORC1 and mTORC2 selectively regulate CD8⁺ T cell differentiation.
Kristen N Pollizzi, Chirag H Patel, Im-Hong Sun, Min-Hee Oh, Adam T Waickman, Jiayu Wen, Greg M Delgoffe, Jonathan D Powell. J Clin Invest 2015
190
4

Understanding the Warburg effect: the metabolic requirements of cell proliferation.
Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
4

T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming.
Kai Yang, Sharad Shrestha, Hu Zeng, Peer W F Karmaus, Geoffrey Neale, Peter Vogel, David A Guertin, Richard F Lamb, Hongbo Chi. Immunity 2013
198
4

Defining the role of mTOR in cancer.
David A Guertin, David M Sabatini. Cancer Cell 2007
4

mTOR, metabolism, and the regulation of T-cell differentiation and function.
Adam T Waickman, Jonathan D Powell. Immunol Rev 2012
227
4

Inhibition of the mTORC pathway in the antiphospholipid syndrome.
Guillaume Canaud, Frank Bienaimé, Fanny Tabarin, Guillaume Bataillon, Danielle Seilhean, Laure-Hélène Noël, Marie-Agnès Dragon-Durey, Renaud Snanoudj, Gérard Friedlander, Lise Halbwachs-Mecarelli,[...]. N Engl J Med 2014
167
4

Autophagy fights disease through cellular self-digestion.
Noboru Mizushima, Beth Levine, Ana Maria Cuervo, Daniel J Klionsky. Nature 2008
4

mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6.
Francesca Nazio, Flavie Strappazzon, Manuela Antonioli, Pamela Bielli, Valentina Cianfanelli, Matteo Bordi, Christine Gretzmeier, Joern Dengjel, Mauro Piacentini, Gian Maria Fimia,[...]. Nat Cell Biol 2013
430
4


mTor mediates tau localization and secretion: Implication for Alzheimer's disease.
Zhi Tang, Eniko Ioja, Erika Bereczki, Kjell Hultenby, Chunxia Li, Zhizhong Guan, Bengt Winblad, Jin-Jing Pei. Biochim Biophys Acta 2015
67
5

The IGF1 P2 promoter is an epigenetic QTL for circulating IGF1 and human growth.
Meriem Ouni, Yasemin Gunes, Marie-Pierre Belot, Anne-Laure Castell, Delphine Fradin, Pierre Bougnères. Clin Epigenetics 2015
27
14

Regulation of mTORC1 by PI3K signaling.
Christian C Dibble, Lewis C Cantley. Trends Cell Biol 2015
367
4

Insulin gene expression is regulated by DNA methylation.
Akio Kuroda, Tibor A Rauch, Ivan Todorov, Hsun Teresa Ku, Ismail H Al-Abdullah, Fouad Kandeel, Yoko Mullen, Gerd P Pfeifer, Kevin Ferreri. PLoS One 2009
171
4


Milk miRNAs: simple nutrients or systemic functional regulators?
Bodo C Melnik, Foteini Kakulas, Donna T Geddes, Peter E Hartmann, Swen Malte John, Pedro Carrera-Bastos, Loren Cordain, Gerd Schmitz. Nutr Metab (Lond) 2016
37
10


microRNA in native and processed cow's milk and its implication for the farm milk effect on asthma.
Benedikt Kirchner, Michael W Pfaffl, Joseph Dumpler, Erika von Mutius, Markus J Ege. J Allergy Clin Immunol 2016
38
10


Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.
Ryan D Michalek, Valerie A Gerriets, Sarah R Jacobs, Andrew N Macintyre, Nancie J MacIver, Emily F Mason, Sarah A Sullivan, Amanda G Nichols, Jeffrey C Rathmell. J Immunol 2011
4


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.