Josiah Gerdts, E J Brace, Yo Sasaki, Aaron DiAntonio, Jeffrey Milbrandt. Science 2015
Times Cited: 282
Times Cited: 282
Times Cited
Times Co-cited
Similarity
dSarm/Sarm1 is required for activation of an injury-induced axon death pathway.
Jeannette M Osterloh, Jing Yang, Timothy M Rooney, A Nicole Fox, Robert Adalbert, Eric H Powell, Amy E Sheehan, Michelle A Avery, Rachel Hackett, Mary A Logan,[...]. Science 2012
Jeannette M Osterloh, Jing Yang, Timothy M Rooney, A Nicole Fox, Robert Adalbert, Eric H Powell, Amy E Sheehan, Michelle A Avery, Rachel Hackett, Mary A Logan,[...]. Science 2012
57
The SARM1 Toll/Interleukin-1 Receptor Domain Possesses Intrinsic NAD+ Cleavage Activity that Promotes Pathological Axonal Degeneration.
Kow Essuman, Daniel W Summers, Yo Sasaki, Xianrong Mao, Aaron DiAntonio, Jeffrey Milbrandt. Neuron 2017
Kow Essuman, Daniel W Summers, Yo Sasaki, Xianrong Mao, Aaron DiAntonio, Jeffrey Milbrandt. Neuron 2017
56
Sarm1-mediated axon degeneration requires both SAM and TIR interactions.
Josiah Gerdts, Daniel W Summers, Yo Sasaki, Aaron DiAntonio, Jeffrey Milbrandt. J Neurosci 2013
Josiah Gerdts, Daniel W Summers, Yo Sasaki, Aaron DiAntonio, Jeffrey Milbrandt. J Neurosci 2013
37
Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons.
Jonathan Gilley, Michael P Coleman. PLoS Biol 2010
Jonathan Gilley, Michael P Coleman. PLoS Biol 2010
32
NAD+ cleavage activity by animal and plant TIR domains in cell death pathways.
Shane Horsefield, Hayden Burdett, Xiaoxiao Zhang, Mohammad K Manik, Yun Shi, Jian Chen, Tiancong Qi, Jonathan Gilley, Jhih-Siang Lai, Maxwell X Rank,[...]. Science 2019
Shane Horsefield, Hayden Burdett, Xiaoxiao Zhang, Mohammad K Manik, Yun Shi, Jian Chen, Tiancong Qi, Jonathan Gilley, Jhih-Siang Lai, Maxwell X Rank,[...]. Science 2019
31
The NAD+-mediated self-inhibition mechanism of pro-neurodegenerative SARM1.
Yuefeng Jiang, Tingting Liu, Chia-Hsueh Lee, Qing Chang, Jing Yang, Zhe Zhang. Nature 2020
Yuefeng Jiang, Tingting Liu, Chia-Hsueh Lee, Qing Chang, Jing Yang, Zhe Zhang. Nature 2020
51
Prevention of vincristine-induced peripheral neuropathy by genetic deletion of SARM1 in mice.
Stefanie Geisler, Ryan A Doan, Amy Strickland, Xin Huang, Jeffrey Milbrandt, Aaron DiAntonio. Brain 2016
Stefanie Geisler, Ryan A Doan, Amy Strickland, Xin Huang, Jeffrey Milbrandt, Aaron DiAntonio. Brain 2016
28
Programmed axon degeneration: from mouse to mechanism to medicine.
Michael P Coleman, Ahmet Höke. Nat Rev Neurosci 2020
Michael P Coleman, Ahmet Höke. Nat Rev Neurosci 2020
34
Deletion of Sarm1 gene is neuroprotective in two models of peripheral neuropathy.
Elliot Turkiew, Debbie Falconer, Nicole Reed, Ahmet Höke. J Peripher Nerv Syst 2017
Elliot Turkiew, Debbie Falconer, Nicole Reed, Ahmet Höke. J Peripher Nerv Syst 2017
29
NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion.
Yo Sasaki, Takashi Nakagawa, Xianrong Mao, Aaron DiAntonio, Jeffrey Milbrandt. Elife 2016
Yo Sasaki, Takashi Nakagawa, Xianrong Mao, Aaron DiAntonio, Jeffrey Milbrandt. Elife 2016
26
A Cell-Permeant Mimetic of NMN Activates SARM1 to Produce Cyclic ADP-Ribose and Induce Non-apoptotic Cell Death.
Zhi Ying Zhao, Xu Jie Xie, Wan Hua Li, Jun Liu, Zhe Chen, Ben Zhang, Ting Li, Song Lu Li, Jun Gang Lu, Liangren Zhang,[...]. iScience 2019
Zhi Ying Zhao, Xu Jie Xie, Wan Hua Li, Jun Liu, Zhe Chen, Ben Zhang, Ting Li, Song Lu Li, Jun Gang Lu, Liangren Zhang,[...]. iScience 2019
32
SARM1 acts downstream of neuroinflammatory and necroptotic signaling to induce axon degeneration.
Kwang Woo Ko, Jeffrey Milbrandt, Aaron DiAntonio. J Cell Biol 2020
Kwang Woo Ko, Jeffrey Milbrandt, Aaron DiAntonio. J Cell Biol 2020
58
Pathological axonal death through a MAPK cascade that triggers a local energy deficit.
Jing Yang, Zhuhao Wu, Nicolas Renier, David J Simon, Kunihiro Uryu, David S Park, Peter A Greer, Cathy Tournier, Roger J Davis, Marc Tessier-Lavigne. Cell 2015
Jing Yang, Zhuhao Wu, Nicolas Renier, David J Simon, Kunihiro Uryu, David S Park, Peter A Greer, Cathy Tournier, Roger J Davis, Marc Tessier-Lavigne. Cell 2015
23
Axon Self-Destruction: New Links among SARM1, MAPKs, and NAD+ Metabolism.
Josiah Gerdts, Daniel W Summers, Jeffrey Milbrandt, Aaron DiAntonio. Neuron 2016
Josiah Gerdts, Daniel W Summers, Jeffrey Milbrandt, Aaron DiAntonio. Neuron 2016
23
Structural and Mechanistic Regulation of the Pro-degenerative NAD Hydrolase SARM1.
Matthew Bratkowski, Tian Xie, Desiree A Thayer, Shradha Lad, Prakhyat Mathur, Yu-San Yang, Gregory Danko, Thomas C Burdett, Jean Danao, Aaron Cantor,[...]. Cell Rep 2020
Matthew Bratkowski, Tian Xie, Desiree A Thayer, Shradha Lad, Prakhyat Mathur, Yu-San Yang, Gregory Danko, Thomas C Burdett, Jean Danao, Aaron Cantor,[...]. Cell Rep 2020
65
Attenuated traumatic axonal injury and improved functional outcome after traumatic brain injury in mice lacking Sarm1.
Nils Henninger, James Bouley, Elif M Sikoglu, Jiyan An, Constance M Moore, Jean A King, Robert Bowser, Marc R Freeman, Robert H Brown. Brain 2016
Nils Henninger, James Bouley, Elif M Sikoglu, Jiyan An, Constance M Moore, Jean A King, Robert Bowser, Marc R Freeman, Robert H Brown. Brain 2016
22
Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene.
T G Mack, M Reiner, B Beirowski, W Mi, M Emanuelli, D Wagner, D Thomson, T Gillingwater, F Court, L Conforti,[...]. Nat Neurosci 2001
T G Mack, M Reiner, B Beirowski, W Mi, M Emanuelli, D Wagner, D Thomson, T Gillingwater, F Court, L Conforti,[...]. Nat Neurosci 2001
21
Absence of SARM1 rescues development and survival of NMNAT2-deficient axons.
Jonathan Gilley, Giuseppe Orsomando, Isabel Nascimento-Ferreira, Michael P Coleman. Cell Rep 2015
Jonathan Gilley, Giuseppe Orsomando, Isabel Nascimento-Ferreira, Michael P Coleman. Cell Rep 2015
21
Small Molecule SARM1 Inhibitors Recapitulate the SARM1-/- Phenotype and Allow Recovery of a Metastable Pool of Axons Fated to Degenerate.
Robert O Hughes, Todd Bosanac, Xianrong Mao, Thomas M Engber, Aaron DiAntonio, Jeffrey Milbrandt, Rajesh Devraj, Raul Krauss. Cell Rep 2021
Robert O Hughes, Todd Bosanac, Xianrong Mao, Thomas M Engber, Aaron DiAntonio, Jeffrey Milbrandt, Rajesh Devraj, Raul Krauss. Cell Rep 2021
60
A local mechanism mediates NAD-dependent protection of axon degeneration.
Jing Wang, Qiwei Zhai, Ying Chen, Estelle Lin, Wei Gu, Michael W McBurney, Zhigang He. J Cell Biol 2005
Jing Wang, Qiwei Zhai, Ying Chen, Estelle Lin, Wei Gu, Michael W McBurney, Zhigang He. J Cell Biol 2005
20
SARM1-specific motifs in the TIR domain enable NAD+ loss and regulate injury-induced SARM1 activation.
Daniel W Summers, Daniel A Gibson, Aaron DiAntonio, Jeffrey Milbrandt. Proc Natl Acad Sci U S A 2016
Daniel W Summers, Daniel A Gibson, Aaron DiAntonio, Jeffrey Milbrandt. Proc Natl Acad Sci U S A 2016
30
A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degeneration.
M Di Stefano, I Nascimento-Ferreira, G Orsomando, V Mori, J Gilley, R Brown, L Janeckova, M E Vargas, L A Worrell, A Loreto,[...]. Cell Death Differ 2015
M Di Stefano, I Nascimento-Ferreira, G Orsomando, V Mori, J Gilley, R Brown, L Janeckova, M E Vargas, L A Worrell, A Loreto,[...]. Cell Death Differ 2015
20
Gene therapy targeting SARM1 blocks pathological axon degeneration in mice.
Stefanie Geisler, Shay X Huang, Amy Strickland, Ryan A Doan, Daniel W Summers, Xianrong Mao, Jiwoong Park, Aaron DiAntonio, Jeffrey Milbrandt. J Exp Med 2019
Stefanie Geisler, Shay X Huang, Amy Strickland, Ryan A Doan, Daniel W Summers, Xianrong Mao, Jiwoong Park, Aaron DiAntonio, Jeffrey Milbrandt. J Exp Med 2019
33
The SARM1 axon degeneration pathway: control of the NAD+ metabolome regulates axon survival in health and disease.
Matthew D Figley, Aaron DiAntonio. Curr Opin Neurobiol 2020
Matthew D Figley, Aaron DiAntonio. Curr Opin Neurobiol 2020
50
Structural basis for SARM1 inhibition and activation under energetic stress.
Michael Sporny, Julia Guez-Haddad, Tami Khazma, Avraham Yaron, Moshe Dessau, Yoel Shkolnisky, Carsten Mim, Michail N Isupov, Ran Zalk, Michael Hons,[...]. Elife 2020
Michael Sporny, Julia Guez-Haddad, Tami Khazma, Avraham Yaron, Moshe Dessau, Yoel Shkolnisky, Carsten Mim, Michail N Isupov, Ran Zalk, Michael Hons,[...]. Elife 2020
60
SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration.
Matthew D Figley, Weixi Gu, Jeffrey D Nanson, Yun Shi, Yo Sasaki, Katie Cunnea, Alpeshkumar K Malde, Xinying Jia, Zhenyao Luo, Forhad K Saikot,[...]. Neuron 2021
Matthew D Figley, Weixi Gu, Jeffrey D Nanson, Yun Shi, Yo Sasaki, Katie Cunnea, Alpeshkumar K Malde, Xinying Jia, Zhenyao Luo, Forhad K Saikot,[...]. Neuron 2021
43
Mitochondrial dysfunction induces Sarm1-dependent cell death in sensory neurons.
Daniel W Summers, Aaron DiAntonio, Jeffrey Milbrandt. J Neurosci 2014
Daniel W Summers, Aaron DiAntonio, Jeffrey Milbrandt. J Neurosci 2014
19
Absence of Wallerian Degeneration does not Hinder Regeneration in Peripheral Nerve.
E R Lunn, V H Perry, M C Brown, H Rosen, S Gordon. Eur J Neurosci 1989
E R Lunn, V H Perry, M C Brown, H Rosen, S Gordon. Eur J Neurosci 1989
19
Wallerian Degeneration Is Executed by an NMN-SARM1-Dependent Late Ca(2+) Influx but Only Modestly Influenced by Mitochondria.
Andrea Loreto, Michele Di Stefano, Martin Gering, Laura Conforti. Cell Rep 2015
Andrea Loreto, Michele Di Stefano, Martin Gering, Laura Conforti. Cell Rep 2015
28
TIR domains of plant immune receptors are NAD+-cleaving enzymes that promote cell death.
Li Wan, Kow Essuman, Ryan G Anderson, Yo Sasaki, Freddy Monteiro, Eui-Hwan Chung, Erin Osborne Nishimura, Aaron DiAntonio, Jeffrey Milbrandt, Jeffery L Dangl,[...]. Science 2019
Li Wan, Kow Essuman, Ryan G Anderson, Yo Sasaki, Freddy Monteiro, Eui-Hwan Chung, Erin Osborne Nishimura, Aaron DiAntonio, Jeffrey Milbrandt, Jeffery L Dangl,[...]. Science 2019
19
TIR Domain Proteins Are an Ancient Family of NAD+-Consuming Enzymes.
Kow Essuman, Daniel W Summers, Yo Sasaki, Xianrong Mao, Aldrin Kay Yuen Yim, Aaron DiAntonio, Jeffrey Milbrandt. Curr Biol 2018
Kow Essuman, Daniel W Summers, Yo Sasaki, Xianrong Mao, Aldrin Kay Yuen Yim, Aaron DiAntonio, Jeffrey Milbrandt. Curr Biol 2018
20
Nicotinamide mononucleotide adenylyl transferase-mediated axonal protection requires enzymatic activity but not increased levels of neuronal nicotinamide adenine dinucleotide.
Yo Sasaki, Bhupinder P S Vohra, Frances E Lund, Jeffrey Milbrandt. J Neurosci 2009
Yo Sasaki, Bhupinder P S Vohra, Frances E Lund, Jeffrey Milbrandt. J Neurosci 2009
18
Mitochondrial impairment activates the Wallerian pathway through depletion of NMNAT2 leading to SARM1-dependent axon degeneration.
Andrea Loreto, Ciaran S Hill, Victoria L Hewitt, Giuseppe Orsomando, Carlo Angeletti, Jonathan Gilley, Cristiano Lucci, Alvaro Sanchez-Martinez, Alexander J Whitworth, Laura Conforti,[...]. Neurobiol Dis 2020
Andrea Loreto, Ciaran S Hill, Victoria L Hewitt, Giuseppe Orsomando, Carlo Angeletti, Jonathan Gilley, Cristiano Lucci, Alvaro Sanchez-Martinez, Alexander J Whitworth, Laura Conforti,[...]. Neurobiol Dis 2020
43
Axons Matter: The Promise of Treating Neurodegenerative Disorders by Targeting SARM1-Mediated Axonal Degeneration.
Raul Krauss, Todd Bosanac, Rajesh Devraj, Thomas Engber, Robert O Hughes. Trends Pharmacol Sci 2020
Raul Krauss, Todd Bosanac, Rajesh Devraj, Thomas Engber, Robert O Hughes. Trends Pharmacol Sci 2020
50
Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration.
Toshiyuki Araki, Yo Sasaki, Jeffrey Milbrandt. Science 2004
Toshiyuki Araki, Yo Sasaki, Jeffrey Milbrandt. Science 2004
16
Pharmacological bypass of NAD+ salvage pathway protects neurons from chemotherapy-induced degeneration.
Hui-Wen Liu, Chadwick B Smith, Mark S Schmidt, Xiaolu A Cambronne, Michael S Cohen, Marie E Migaud, Charles Brenner, Richard H Goodman. Proc Natl Acad Sci U S A 2018
Hui-Wen Liu, Chadwick B Smith, Mark S Schmidt, Xiaolu A Cambronne, Michael S Cohen, Marie E Migaud, Charles Brenner, Richard H Goodman. Proc Natl Acad Sci U S A 2018
26
NMN Deamidase Delays Wallerian Degeneration and Rescues Axonal Defects Caused by NMNAT2 Deficiency In Vivo.
Michele Di Stefano, Andrea Loreto, Giuseppe Orsomando, Valerio Mori, Federica Zamporlini, Richard P Hulse, Jamie Webster, Lucy F Donaldson, Martin Gering, Nadia Raffaelli,[...]. Curr Biol 2017
Michele Di Stefano, Andrea Loreto, Giuseppe Orsomando, Valerio Mori, Federica Zamporlini, Richard P Hulse, Jamie Webster, Lucy F Donaldson, Martin Gering, Nadia Raffaelli,[...]. Curr Biol 2017
26
Wallerian degeneration: an emerging axon death pathway linking injury and disease.
Laura Conforti, Jonathan Gilley, Michael P Coleman. Nat Rev Neurosci 2014
Laura Conforti, Jonathan Gilley, Michael P Coleman. Nat Rev Neurosci 2014
16
cADPR is a gene dosage-sensitive biomarker of SARM1 activity in healthy, compromised, and degenerating axons.
Yo Sasaki, Thomas M Engber, Robert O Hughes, Matthew D Figley, Tong Wu, Todd Bosanac, Rajesh Devraj, Jeffrey Milbrandt, Raul Krauss, Aaron DiAntonio. Exp Neurol 2020
Yo Sasaki, Thomas M Engber, Robert O Hughes, Matthew D Figley, Tong Wu, Todd Bosanac, Rajesh Devraj, Jeffrey Milbrandt, Raul Krauss, Aaron DiAntonio. Exp Neurol 2020
55
NAD+ in Brain Aging and Neurodegenerative Disorders.
Sofie Lautrup, David A Sinclair, Mark P Mattson, Evandro F Fang. Cell Metab 2019
Sofie Lautrup, David A Sinclair, Mark P Mattson, Evandro F Fang. Cell Metab 2019
15
CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism.
Juliana Camacho-Pereira, Mariana G Tarragó, Claudia C S Chini, Veronica Nin, Carlos Escande, Gina M Warner, Amrutesh S Puranik, Renee A Schoon, Joel M Reid, Antonio Galina,[...]. Cell Metab 2016
Juliana Camacho-Pereira, Mariana G Tarragó, Claudia C S Chini, Veronica Nin, Carlos Escande, Gina M Warner, Amrutesh S Puranik, Renee A Schoon, Joel M Reid, Antonio Galina,[...]. Cell Metab 2016
15
Emergence of SARM1 as a Potential Therapeutic Target for Wallerian-type Diseases.
Heather S Loring, Paul R Thompson. Cell Chem Biol 2020
Heather S Loring, Paul R Thompson. Cell Chem Biol 2020
53
Structural Evidence for an Octameric Ring Arrangement of SARM1.
Michael Sporny, Julia Guez-Haddad, Mario Lebendiker, Valeria Ulisse, Allison Volf, Carsten Mim, Michail N Isupov, Yarden Opatowsky. J Mol Biol 2019
Michael Sporny, Julia Guez-Haddad, Mario Lebendiker, Valeria Ulisse, Allison Volf, Carsten Mim, Michail N Isupov, Yarden Opatowsky. J Mol Biol 2019
50
Sarm1 deletion reduces axon damage, demyelination, and white matter atrophy after experimental traumatic brain injury.
Christina M Marion, Dennis P McDaniel, Regina C Armstrong. Exp Neurol 2019
Christina M Marion, Dennis P McDaniel, Regina C Armstrong. Exp Neurol 2019
48
NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus.
Carles Cantó, Keir J Menzies, Johan Auwerx. Cell Metab 2015
Carles Cantó, Keir J Menzies, Johan Auwerx. Cell Metab 2015
14
MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2.
Lauren J Walker, Daniel W Summers, Yo Sasaki, E J Brace, Jeffrey Milbrandt, Aaron DiAntonio. Elife 2017
Lauren J Walker, Daniel W Summers, Yo Sasaki, E J Brace, Jeffrey Milbrandt, Aaron DiAntonio. Elife 2017
14
Vincristine and bortezomib use distinct upstream mechanisms to activate a common SARM1-dependent axon degeneration program.
Stefanie Geisler, Ryan A Doan, Galen C Cheng, Aysel Cetinkaya-Fisgin, Shay X Huang, Ahmet Höke, Jeffrey Milbrandt, Aaron DiAntonio. JCI Insight 2019
Stefanie Geisler, Ryan A Doan, Galen C Cheng, Aysel Cetinkaya-Fisgin, Shay X Huang, Ahmet Höke, Jeffrey Milbrandt, Aaron DiAntonio. JCI Insight 2019
30
Axon Death Pathways Converge on Axundead to Promote Functional and Structural Axon Disassembly.
Lukas J Neukomm, Thomas C Burdett, Andrew M Seeds, Stefanie Hampel, Jaeda C Coutinho-Budd, Jonathan E Farley, Jack Wong, Yonca B Karadeniz, Jeannette M Osterloh, Amy E Sheehan,[...]. Neuron 2017
Lukas J Neukomm, Thomas C Burdett, Andrew M Seeds, Stefanie Hampel, Jaeda C Coutinho-Budd, Jonathan E Farley, Jack Wong, Yonca B Karadeniz, Jeannette M Osterloh, Amy E Sheehan,[...]. Neuron 2017
25
Nicotinamide mononucleotide adenylyltransferase expression in mitochondrial matrix delays Wallerian degeneration.
Naoki Yahata, Shigeki Yuasa, Toshiyuki Araki. J Neurosci 2009
Naoki Yahata, Shigeki Yuasa, Toshiyuki Araki. J Neurosci 2009
12
c-Jun N-terminal kinase (JNK)-mediated phosphorylation of SARM1 regulates NAD+ cleavage activity to inhibit mitochondrial respiration.
Hitoshi Murata, Cho Cho Khine, Akane Nishikawa, Ken-Ichi Yamamoto, Rie Kinoshita, Masakiyo Sakaguchi. J Biol Chem 2018
Hitoshi Murata, Cho Cho Khine, Akane Nishikawa, Ken-Ichi Yamamoto, Rie Kinoshita, Masakiyo Sakaguchi. J Biol Chem 2018
33
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.