Itaru Kojima, Yuko Nakagawa, Yoshiaki Ohtsu, Kunihisa Hamano, Johan Medina, Masahiro Nagasawa. J Diabetes Investig 2015
Times Cited: 24
Times Cited: 24
Times Cited
Times Co-cited
Similarity
Glucose promotes its own metabolism by acting on the cell-surface glucose-sensing receptor T1R3.
Yuko Nakagawa, Yoshiaki Ohtsu, Masahiro Nagasawa, Hiroshi Shibata, Itaru Kojima. Endocr J 2014
Yuko Nakagawa, Yoshiaki Ohtsu, Masahiro Nagasawa, Hiroshi Shibata, Itaru Kojima. Endocr J 2014
45
Sweet taste receptor expressed in pancreatic beta-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion.
Yuko Nakagawa, Masahiro Nagasawa, Satoko Yamada, Akemi Hara, Hideo Mogami, Viacheslav O Nikolaev, Martin J Lohse, Noriatsu Shigemura, Yuzo Ninomiya, Itaru Kojima. PLoS One 2009
Yuko Nakagawa, Masahiro Nagasawa, Satoko Yamada, Akemi Hara, Hideo Mogami, Viacheslav O Nikolaev, Martin J Lohse, Noriatsu Shigemura, Yuzo Ninomiya, Itaru Kojima. PLoS One 2009
45
Mammalian sweet taste receptors.
G Nelson, M A Hoon, J Chandrashekar, Y Zhang, N J Ryba, C S Zuker. Cell 2001
G Nelson, M A Hoon, J Chandrashekar, Y Zhang, N J Ryba, C S Zuker. Cell 2001
41
Multimodal function of the sweet taste receptor expressed in pancreatic β-cells: generation of diverse patterns of intracellular signals by sweet agonists.
Yuko Nakagawa, Masahiro Nagasawa, Hideo Mogami, Martin Lohse, Yuzo Ninomiya, Itaru Kojima. Endocr J 2013
Yuko Nakagawa, Masahiro Nagasawa, Hideo Mogami, Martin Lohse, Yuzo Ninomiya, Itaru Kojima. Endocr J 2013
37
Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1.
Hyeung-Jin Jang, Zaza Kokrashvili, Michael J Theodorakis, Olga D Carlson, Byung-Joon Kim, Jie Zhou, Hyeon Ho Kim, Xiangru Xu, Sic L Chan, Magdalena Juhaszova,[...]. Proc Natl Acad Sci U S A 2007
Hyeung-Jin Jang, Zaza Kokrashvili, Michael J Theodorakis, Olga D Carlson, Byung-Joon Kim, Jie Zhou, Hyeon Ho Kim, Xiangru Xu, Sic L Chan, Magdalena Juhaszova,[...]. Proc Natl Acad Sci U S A 2007
33
Regulation of insulin secretion: a matter of phase control and amplitude modulation.
J C Henquin. Diabetologia 2009
J C Henquin. Diabetologia 2009
33
Sweet taste receptor signaling in beta cells mediates fructose-induced potentiation of glucose-stimulated insulin secretion.
George A Kyriazis, Mangala M Soundarapandian, Björn Tyrberg. Proc Natl Acad Sci U S A 2012
George A Kyriazis, Mangala M Soundarapandian, Björn Tyrberg. Proc Natl Acad Sci U S A 2012
25
Lactisole inhibits the glucose-sensing receptor T1R3 expressed in mouse pancreatic β-cells.
Kunihisa Hamano, Yuko Nakagawa, Yoshiaki Ohtsu, Longfei Li, Johan Medina, Yuji Tanaka, Katsuyoshi Masuda, Mitsuhisa Komatsu, Itaru Kojima. J Endocrinol 2015
Kunihisa Hamano, Yuko Nakagawa, Yoshiaki Ohtsu, Longfei Li, Johan Medina, Yuji Tanaka, Katsuyoshi Masuda, Mitsuhisa Komatsu, Itaru Kojima. J Endocrinol 2015
27
Glucose Evokes Rapid Ca2+ and Cyclic AMP Signals by Activating the Cell-Surface Glucose-Sensing Receptor in Pancreatic β-Cells.
Yuko Nakagawa, Masahiro Nagasawa, Johan Medina, Itaru Kojima. PLoS One 2015
Yuko Nakagawa, Masahiro Nagasawa, Johan Medina, Itaru Kojima. PLoS One 2015
54
Artificial sweeteners induce glucose intolerance by altering the gut microbiota.
Jotham Suez, Tal Korem, David Zeevi, Gili Zilberman-Schapira, Christoph A Thaiss, Ori Maza, David Israeli, Niv Zmora, Shlomit Gilad, Adina Weinberger,[...]. Nature 2014
Jotham Suez, Tal Korem, David Zeevi, Gili Zilberman-Schapira, Christoph A Thaiss, Ori Maza, David Israeli, Niv Zmora, Shlomit Gilad, Adina Weinberger,[...]. Nature 2014
25
T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1.
Robert F Margolskee, Jane Dyer, Zaza Kokrashvili, Kieron S H Salmon, Erwin Ilegems, Kristian Daly, Emeline L Maillet, Yuzo Ninomiya, Bedrich Mosinger, Soraya P Shirazi-Beechey. Proc Natl Acad Sci U S A 2007
Robert F Margolskee, Jane Dyer, Zaza Kokrashvili, Kieron S H Salmon, Erwin Ilegems, Kristian Daly, Emeline L Maillet, Yuzo Ninomiya, Bedrich Mosinger, Soraya P Shirazi-Beechey. Proc Natl Acad Sci U S A 2007
20
Expression of the glucose-sensing receptor T1R3 in pancreatic islet: changes in the expression levels in various nutritional and metabolic states.
Anya Medina, Yuko Nakagawa, Jinhui Ma, Longfei Li, Kunihisa Hamano, Toshio Akimoto, Yuzo Ninomiya, Itaru Kojima. Endocr J 2014
Anya Medina, Yuko Nakagawa, Jinhui Ma, Longfei Li, Kunihisa Hamano, Toshio Akimoto, Yuzo Ninomiya, Itaru Kojima. Endocr J 2014
25
Lactisole interacts with the transmembrane domains of human T1R3 to inhibit sweet taste.
Peihua Jiang, Meng Cui, Baohua Zhao, Zhan Liu, Lenore A Snyder, Lumie M J Benard, Roman Osman, Robert F Margolskee, Marianna Max. J Biol Chem 2005
Peihua Jiang, Meng Cui, Baohua Zhao, Zhan Liu, Lenore A Snyder, Lumie M J Benard, Roman Osman, Robert F Margolskee, Marianna Max. J Biol Chem 2005
20
Glucose-Sensing Receptor T1R3: A New Signaling Receptor Activated by Glucose in Pancreatic β-Cells.
Itaru Kojima, Yuko Nakagawa, Kunihisa Hamano, Johan Medina, Longfei Li, Masahiro Nagasawa. Biol Pharm Bull 2015
Itaru Kojima, Yuko Nakagawa, Kunihisa Hamano, Johan Medina, Longfei Li, Masahiro Nagasawa. Biol Pharm Bull 2015
26
Sucralose metabolism and pharmacokinetics in man.
A Roberts, A G Renwick, J Sims, D J Snodin. Food Chem Toxicol 2000
A Roberts, A G Renwick, J Sims, D J Snodin. Food Chem Toxicol 2000
20
Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms.
J Miyazaki, K Araki, E Yamato, H Ikegami, T Asano, Y Shibasaki, Y Oka, K Yamamura. Endocrinology 1990
J Miyazaki, K Araki, E Yamato, H Ikegami, T Asano, Y Shibasaki, Y Oka, K Yamamura. Endocrinology 1990
16
The sweet taste receptor: a single receptor with multiple sites and modes of interaction.
Pierandrea Temussi. Adv Food Nutr Res 2007
Pierandrea Temussi. Adv Food Nutr Res 2007
16
A novel regulatory function of sweet taste-sensing receptor in adipogenic differentiation of 3T3-L1 cells.
Yosuke Masubuchi, Yuko Nakagawa, Jinhui Ma, Tsutomu Sasaki, Tadahiro Kitamura, Yoritsuna Yamamoto, Hitoshi Kurose, Itaru Kojima, Hiroshi Shibata. PLoS One 2013
Yosuke Masubuchi, Yuko Nakagawa, Jinhui Ma, Tsutomu Sasaki, Tadahiro Kitamura, Yoritsuna Yamamoto, Hitoshi Kurose, Itaru Kojima, Hiroshi Shibata. PLoS One 2013
16
Transformation of postingestive glucose responses after deletion of sweet taste receptor subunits or gastric bypass surgery.
Maartje C P Geraedts, Tatsuyuki Takahashi, Stephan Vigues, Michele L Markwardt, Andongfac Nkobena, Renee E Cockerham, Andras Hajnal, Cedrick D Dotson, Mark A Rizzo, Steven D Munger. Am J Physiol Endocrinol Metab 2012
Maartje C P Geraedts, Tatsuyuki Takahashi, Stephan Vigues, Michele L Markwardt, Andongfac Nkobena, Renee E Cockerham, Andras Hajnal, Cedrick D Dotson, Mark A Rizzo, Steven D Munger. Am J Physiol Endocrinol Metab 2012
16
Diverse signaling systems activated by the sweet taste receptor in human GLP-1-secreting cells.
Yoshiaki Ohtsu, Yuko Nakagawa, Masahiro Nagasawa, Shigeki Takeda, Hirokazu Arakawa, Itaru Kojima. Mol Cell Endocrinol 2014
Yoshiaki Ohtsu, Yuko Nakagawa, Masahiro Nagasawa, Shigeki Takeda, Hirokazu Arakawa, Itaru Kojima. Mol Cell Endocrinol 2014
16
Physiology and pathophysiology of insulin secretion.
H Rasmussen, K C Zawalich, S Ganesan, R Calle, W S Zawalich. Diabetes Care 1990
H Rasmussen, K C Zawalich, S Ganesan, R Calle, W S Zawalich. Diabetes Care 1990
16
Metabolic signaling in fuel-induced insulin secretion.
Marc Prentki, Franz M Matschinsky, S R Murthy Madiraju. Cell Metab 2013
Marc Prentki, Franz M Matschinsky, S R Murthy Madiraju. Cell Metab 2013
16
Sucralose affects glycemic and hormonal responses to an oral glucose load.
M Yanina Pepino, Courtney D Tiemann, Bruce W Patterson, Burton M Wice, Samuel Klein. Diabetes Care 2013
M Yanina Pepino, Courtney D Tiemann, Bruce W Patterson, Burton M Wice, Samuel Klein. Diabetes Care 2013
16
Novel single chain cAMP sensors for receptor-induced signal propagation.
Viacheslav O Nikolaev, Moritz Bünemann, Lutz Hein, Annette Hannawacker, Martin J Lohse. J Biol Chem 2004
Viacheslav O Nikolaev, Moritz Bünemann, Lutz Hein, Annette Hannawacker, Martin J Lohse. J Biol Chem 2004
12
Amino acid taste receptor regulates insulin secretion in pancreatic β-cell line MIN6 cells.
Manami Oya, Hideyuki Suzuki, Yuichiro Watanabe, Moritoshi Sato, Takashi Tsuboi. Genes Cells 2011
Manami Oya, Hideyuki Suzuki, Yuichiro Watanabe, Moritoshi Sato, Takashi Tsuboi. Genes Cells 2011
12
SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells.
Balrik Kailey, Martijn van de Bunt, Stephen Cheley, Paul R Johnson, Patrick E MacDonald, Anna L Gloyn, Patrik Rorsman, Matthias Braun. Am J Physiol Endocrinol Metab 2012
Balrik Kailey, Martijn van de Bunt, Stephen Cheley, Paul R Johnson, Patrick E MacDonald, Anna L Gloyn, Patrik Rorsman, Matthias Braun. Am J Physiol Endocrinol Metab 2012
12
12
Incretin-modulated beta cell energetics in intact islets of Langerhans.
David J Hodson, Andrei I Tarasov, Silvia Gimeno Brias, Ryan K Mitchell, Natalie R Johnston, Shahab Haghollahi, Matthew C Cane, Marco Bugliani, Piero Marchetti, Domenico Bosco,[...]. Mol Endocrinol 2014
David J Hodson, Andrei I Tarasov, Silvia Gimeno Brias, Ryan K Mitchell, Natalie R Johnston, Shahab Haghollahi, Matthew C Cane, Marco Bugliani, Piero Marchetti, Domenico Bosco,[...]. Mol Endocrinol 2014
12
Glucagon-like peptide 1 activates protein kinase C through Ca2+-dependent activation of phospholipase C in insulin-secreting cells.
Yuko Suzuki, Hui Zhang, Naoaki Saito, Itaru Kojima, Tetsumei Urano, Hideo Mogami. J Biol Chem 2006
Yuko Suzuki, Hui Zhang, Naoaki Saito, Itaru Kojima, Tetsumei Urano, Hideo Mogami. J Biol Chem 2006
12
Glucokinase as glucose sensor and metabolic signal generator in pancreatic beta-cells and hepatocytes.
F M Matschinsky. Diabetes 1990
F M Matschinsky. Diabetes 1990
12
Cyclic AMP signaling in pancreatic islets.
Brian Furman, Wee Kiat Ong, Nigel J Pyne. Adv Exp Med Biol 2010
Brian Furman, Wee Kiat Ong, Nigel J Pyne. Adv Exp Med Biol 2010
12
Intracellular ATP directly blocks K+ channels in pancreatic B-cells.
D L Cook, C N Hales. Nature 1984
D L Cook, C N Hales. Nature 1984
12
Oscillations of sub-membrane ATP in glucose-stimulated beta cells depend on negative feedback from Ca(2+).
J Li, H Y Shuai, E Gylfe, A Tengholm. Diabetologia 2013
J Li, H Y Shuai, E Gylfe, A Tengholm. Diabetologia 2013
12
Glucose-stimulated insulin secretion: A newer perspective.
Mitsuhisa Komatsu, Masahiro Takei, Hiroaki Ishii, Yoshihiko Sato. J Diabetes Investig 2013
Mitsuhisa Komatsu, Masahiro Takei, Hiroaki Ishii, Yoshihiko Sato. J Diabetes Investig 2013
12
The development and applications of sucralose, a new high-intensity sweetener.
I Knight. Can J Physiol Pharmacol 1994
I Knight. Can J Physiol Pharmacol 1994
12
Characterization of glucosensing neuron subpopulations in the arcuate nucleus: integration in neuropeptide Y and pro-opio melanocortin networks?
Xavier Fioramonti, Sylvain Contié, Zhentao Song, Vanessa H Routh, Anne Lorsignol, Luc Pénicaud. Diabetes 2007
Xavier Fioramonti, Sylvain Contié, Zhentao Song, Vanessa H Routh, Anne Lorsignol, Luc Pénicaud. Diabetes 2007
12
The metabolic fate of sucralose in rats.
J Sims, A Roberts, J W Daniel, A G Renwick. Food Chem Toxicol 2000
J Sims, A Roberts, J W Daniel, A G Renwick. Food Chem Toxicol 2000
12
Sweet taste signaling functions as a hypothalamic glucose sensor.
Xueying Ren, Ligang Zhou, Rose Terwilliger, Samuel S Newton, Ivan E de Araujo. Front Integr Neurosci 2009
Xueying Ren, Ligang Zhou, Rose Terwilliger, Samuel S Newton, Ivan E de Araujo. Front Integr Neurosci 2009
12
Sweet taste receptors in rat small intestine stimulate glucose absorption through apical GLUT2.
Oliver J Mace, Julie Affleck, Nick Patel, George L Kellett. J Physiol 2007
Oliver J Mace, Julie Affleck, Nick Patel, George L Kellett. J Physiol 2007
12
Sweet Taste-Sensing Receptors Expressed in Pancreatic β-Cells: Sweet Molecules Act as Biased Agonists.
Itaru Kojima, Yuko Nakagawa, Yoshiaki Ohtsu, Anya Medina, Masahiro Nagasawa. Endocrinol Metab (Seoul) 2014
Itaru Kojima, Yuko Nakagawa, Yoshiaki Ohtsu, Anya Medina, Masahiro Nagasawa. Endocrinol Metab (Seoul) 2014
12
Disruption of the sugar-sensing receptor T1R2 attenuates metabolic derangements associated with diet-induced obesity.
Kathleen R Smith, Tania Hussain, Elnaz Karimian Azari, Jennifer L Steiner, Julio E Ayala, Richard E Pratley, George A Kyriazis. Am J Physiol Endocrinol Metab 2016
Kathleen R Smith, Tania Hussain, Elnaz Karimian Azari, Jennifer L Steiner, Julio E Ayala, Richard E Pratley, George A Kyriazis. Am J Physiol Endocrinol Metab 2016
12
Detection of sweet and umami taste in the absence of taste receptor T1r3.
Sami Damak, Minqing Rong, Keiko Yasumatsu, Zaza Kokrashvili, Vijaya Varadarajan, Shiying Zou, Peihua Jiang, Yuzo Ninomiya, Robert F Margolskee. Science 2003
Sami Damak, Minqing Rong, Keiko Yasumatsu, Zaza Kokrashvili, Vijaya Varadarajan, Shiying Zou, Peihua Jiang, Yuzo Ninomiya, Robert F Margolskee. Science 2003
12
The G protein-coupled taste receptor T1R1/T1R3 regulates mTORC1 and autophagy.
Eric M Wauson, Elma Zaganjor, A-Young Lee, Marcy L Guerra, Anwesha B Ghosh, Angie L Bookout, Chris P Chambers, Arif Jivan, Kathleen McGlynn, Michele R Hutchison,[...]. Mol Cell 2012
Eric M Wauson, Elma Zaganjor, A-Young Lee, Marcy L Guerra, Anwesha B Ghosh, Angie L Bookout, Chris P Chambers, Arif Jivan, Kathleen McGlynn, Michele R Hutchison,[...]. Mol Cell 2012
12
Sucralose, an activator of the glucose-sensing receptor, increases ATP by calcium-dependent and -independent mechanisms.
Longfei Li, Yoshiaki Ohtsu, Yuko Nakagawa, Katsuyoshi Masuda, Itaru Kojima. Endocr J 2016
Longfei Li, Yoshiaki Ohtsu, Yuko Nakagawa, Katsuyoshi Masuda, Itaru Kojima. Endocr J 2016
42
Functional roles of the sweet taste receptor in oral and extraoral tissues.
Anni Laffitte, Fabrice Neiers, Loïc Briand. Curr Opin Clin Nutr Metab Care 2014
Anni Laffitte, Fabrice Neiers, Loïc Briand. Curr Opin Clin Nutr Metab Care 2014
12
The receptors for mammalian sweet and umami taste.
Grace Q Zhao, Yifeng Zhang, Mark A Hoon, Jayaram Chandrashekar, Isolde Erlenbach, Nicholas J P Ryba, Charles S Zuker. Cell 2003
Grace Q Zhao, Yifeng Zhang, Mark A Hoon, Jayaram Chandrashekar, Isolde Erlenbach, Nicholas J P Ryba, Charles S Zuker. Cell 2003
12
Glutamate acts as a key signal linking glucose metabolism to incretin/cAMP action to amplify insulin secretion.
Ghupurjan Gheni, Masahito Ogura, Masahiro Iwasaki, Norihide Yokoi, Kohtaro Minami, Yasumune Nakayama, Kazuo Harada, Benoit Hastoy, Xichen Wu, Harumi Takahashi,[...]. Cell Rep 2014
Ghupurjan Gheni, Masahito Ogura, Masahiro Iwasaki, Norihide Yokoi, Kohtaro Minami, Yasumune Nakayama, Kazuo Harada, Benoit Hastoy, Xichen Wu, Harumi Takahashi,[...]. Cell Rep 2014
12
Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets.
Alice E Adriaenssens, Berit Svendsen, Brian Y H Lam, Giles S H Yeo, Jens J Holst, Frank Reimann, Fiona M Gribble. Diabetologia 2016
Alice E Adriaenssens, Berit Svendsen, Brian Y H Lam, Giles S H Yeo, Jens J Holst, Frank Reimann, Fiona M Gribble. Diabetologia 2016
12
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.