Kathleen Wallace, Jenna D Strickland, Pablo Valdivia, William R Mundy, Timothy J Shafer. Neurotoxicology 2015
Times Cited: 37
Times Cited: 37
Times Cited
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Multi-well microelectrode array recordings detect neuroactivity of ToxCast compounds.
Pablo Valdivia, Matt Martin, William R LeFew, James Ross, Keith A Houck, Timothy J Shafer. Neurotoxicology 2014
Pablo Valdivia, Matt Martin, William R LeFew, James Ross, Keith A Houck, Timothy J Shafer. Neurotoxicology 2014
59
Microelectrode arrays: a physiologically based neurotoxicity testing platform for the 21st century.
Andrew F M Johnstone, Guenter W Gross, Dieter G Weiss, Olaf H-U Schroeder, Alexandra Gramowski, Timothy J Shafer. Neurotoxicology 2010
Andrew F M Johnstone, Guenter W Gross, Dieter G Weiss, Olaf H-U Schroeder, Alexandra Gramowski, Timothy J Shafer. Neurotoxicology 2010
54
Evaluation of multi-well microelectrode arrays for neurotoxicity screening using a chemical training set.
Emma R McConnell, Maxine A McClain, James Ross, William R Lefew, Timothy J Shafer. Neurotoxicology 2012
Emma R McConnell, Maxine A McClain, James Ross, William R Lefew, Timothy J Shafer. Neurotoxicology 2012
43
Application of micro-electrode arrays (MEAs) as an emerging technology for developmental neurotoxicity: evaluation of domoic acid-induced effects in primary cultures of rat cortical neurons.
Helena T Hogberg, Tomasz Sobanski, Antonio Novellino, Maurice Whelan, Dieter G Weiss, Anna K Bal-Price. Neurotoxicology 2011
Helena T Hogberg, Tomasz Sobanski, Antonio Novellino, Maurice Whelan, Dieter G Weiss, Anna K Bal-Price. Neurotoxicology 2011
43
Burst and principal components analyses of MEA data for 16 chemicals describe at least three effects classes.
Cina M Mack, Bryant J Lin, James D Turner, Andrew F M Johnstone, Lyle D Burgoon, Timothy J Shafer. Neurotoxicology 2014
Cina M Mack, Bryant J Lin, James D Turner, Andrew F M Johnstone, Lyle D Burgoon, Timothy J Shafer. Neurotoxicology 2014
40
Detection of marine neurotoxins in food safety testing using a multielectrode array.
Jonathan Nicolas, Peter J M Hendriksen, Regina G D M van Kleef, Aart de Groot, Toine F H Bovee, Ivonne M C M Rietjens, Remco H S Westerink. Mol Nutr Food Res 2014
Jonathan Nicolas, Peter J M Hendriksen, Regina G D M van Kleef, Aart de Groot, Toine F H Bovee, Ivonne M C M Rietjens, Remco H S Westerink. Mol Nutr Food Res 2014
35
In vitro assessment of developmental neurotoxicity: use of microelectrode arrays to measure functional changes in neuronal network ontogeny.
Brian L Robinette, Joshua A Harrill, William R Mundy, Timothy J Shafer. Front Neuroeng 2011
Brian L Robinette, Joshua A Harrill, William R Mundy, Timothy J Shafer. Front Neuroeng 2011
32
Development of micro-electrode array based tests for neurotoxicity: assessment of interlaboratory reproducibility with neuroactive chemicals.
A Novellino, Bibiana Scelfo, T Palosaari, A Price, Tomasz Sobanski, T J Shafer, A F M Johnstone, G W Gross, A Gramowski, O Schroeder,[...]. Front Neuroeng 2011
A Novellino, Bibiana Scelfo, T Palosaari, A Price, Tomasz Sobanski, T J Shafer, A F M Johnstone, G W Gross, A Gramowski, O Schroeder,[...]. Front Neuroeng 2011
32
Feasibility Assessment of Micro-Electrode Chip Assay as a Method of Detecting Neurotoxicity in vitro.
Enrico Defranchi, Antonio Novellino, Maurice Whelan, Sandra Vogel, Tzutzuy Ramirez, Ben van Ravenzwaay, Robert Landsiedel. Front Neuroeng 2011
Enrico Defranchi, Antonio Novellino, Maurice Whelan, Sandra Vogel, Tzutzuy Ramirez, Ben van Ravenzwaay, Robert Landsiedel. Front Neuroeng 2011
24
Neurotoxicity screening of (illicit) drugs using novel methods for analysis of microelectrode array (MEA) recordings.
L Hondebrink, A H A Verboven, W S Drega, S Schmeink, M W G D M de Groot, R G D M van Kleef, F M J Wijnolts, A de Groot, J Meulenbelt, R H S Westerink. Neurotoxicology 2016
L Hondebrink, A H A Verboven, W S Drega, S Schmeink, M W G D M de Groot, R G D M van Kleef, F M J Wijnolts, A de Groot, J Meulenbelt, R H S Westerink. Neurotoxicology 2016
24
Characterization of Early Cortical Neural Network Development in Multiwell Microelectrode Array Plates.
Ellese Cotterill, Diana Hall, Kathleen Wallace, William R Mundy, Stephen J Eglen, Timothy J Shafer. J Biomol Screen 2016
Ellese Cotterill, Diana Hall, Kathleen Wallace, William R Mundy, Stephen J Eglen, Timothy J Shafer. J Biomol Screen 2016
25
Use of high content image analysis to detect chemical-induced changes in synaptogenesis in vitro.
Joshua A Harrill, Brian L Robinette, William R Mundy. Toxicol In Vitro 2011
Joshua A Harrill, Brian L Robinette, William R Mundy. Toxicol In Vitro 2011
21
In vitro microelectrode array technology and neural recordings.
Yoonkey Nam, Bruce C Wheeler. Crit Rev Biomed Eng 2011
Yoonkey Nam, Bruce C Wheeler. Crit Rev Biomed Eng 2011
21
An extremely rich repertoire of bursting patterns during the development of cortical cultures.
Daniel A Wagenaar, Jerome Pine, Steve M Potter. BMC Neurosci 2006
Daniel A Wagenaar, Jerome Pine, Steve M Potter. BMC Neurosci 2006
21
Is the time right for in vitro neurotoxicity testing using human iPSC-derived neurons?
Anke M Tukker, Martje W G D M de Groot, Fiona M J Wijnolts, Emma E J Kasteel, Laura Hondebrink, Remco H S Westerink. ALTEX 2016
Anke M Tukker, Martje W G D M de Groot, Fiona M J Wijnolts, Emma E J Kasteel, Laura Hondebrink, Remco H S Westerink. ALTEX 2016
21
A multi-laboratory evaluation of microelectrode array-based measurements of neural network activity for acute neurotoxicity testing.
Andrea Vassallo, Michela Chiappalone, Ricardo De Camargos Lopes, Bibiana Scelfo, Antonio Novellino, Enrico Defranchi, Taina Palosaari, Timo Weisschu, Tzutzuy Ramirez, Sergio Martinoia,[...]. Neurotoxicology 2017
Andrea Vassallo, Michela Chiappalone, Ricardo De Camargos Lopes, Bibiana Scelfo, Antonio Novellino, Enrico Defranchi, Taina Palosaari, Timo Weisschu, Tzutzuy Ramirez, Sergio Martinoia,[...]. Neurotoxicology 2017
21
Sensitivity of immature neurons in culture to metal-induced changes in reactive oxygen species and intracellular free calcium.
W R Mundy, T M Freudenrich. Neurotoxicology 2000
W R Mundy, T M Freudenrich. Neurotoxicology 2000
18
Complete inhibition of spontaneous activity in neuronal networks in vitro by deltamethrin and permethrin.
T J Shafer, S O Rijal, G W Gross. Neurotoxicology 2008
T J Shafer, S O Rijal, G W Gross. Neurotoxicology 2008
18
Multiparametric characterisation of neuronal network activity for in vitro agrochemical neurotoxicity assessment.
Susanna Alloisio, Mario Nobile, Antonio Novellino. Neurotoxicology 2015
Susanna Alloisio, Mario Nobile, Antonio Novellino. Neurotoxicology 2015
35
Dissociated cortical networks show spontaneously correlated activity patterns during in vitro development.
Michela Chiappalone, Marco Bove, Alessandro Vato, Mariateresa Tedesco, Sergio Martinoia. Brain Res 2006
Michela Chiappalone, Marco Bove, Alessandro Vato, Mariateresa Tedesco, Sergio Martinoia. Brain Res 2006
18
Cortical cultures coupled to micro-electrode arrays: a novel approach to perform in vitro excitotoxicity testing.
Monica Frega, Valentina Pasquale, Mariateresa Tedesco, Manuela Marcoli, Andrea Contestabile, Marina Nanni, Laura Bonzano, Guido Maura, Michela Chiappalone. Neurotoxicol Teratol 2012
Monica Frega, Valentina Pasquale, Mariateresa Tedesco, Manuela Marcoli, Andrea Contestabile, Marina Nanni, Laura Bonzano, Guido Maura, Michela Chiappalone. Neurotoxicol Teratol 2012
18
Use of high content image analyses to detect chemical-mediated effects on neurite sub-populations in primary rat cortical neurons.
Joshua A Harrill, Brian L Robinette, Theresa Freudenrich, William R Mundy. Neurotoxicology 2013
Joshua A Harrill, Brian L Robinette, Theresa Freudenrich, William R Mundy. Neurotoxicology 2013
16
Chronic 14-day exposure to insecticides or methylmercury modulates neuronal activity in primary rat cortical cultures.
Milou M L Dingemans, Marijke G Schütte, Daphne M M Wiersma, Aart de Groot, Regina G D M van Kleef, Fiona M J Wijnolts, Remco H S Westerink. Neurotoxicology 2016
Milou M L Dingemans, Marijke G Schütte, Daphne M M Wiersma, Aart de Groot, Regina G D M van Kleef, Fiona M J Wijnolts, Remco H S Westerink. Neurotoxicology 2016
25
From the Cover: Developmental Neurotoxicants Disrupt Activity in Cortical Networks on Microelectrode Arrays: Results of Screening 86 Compounds During Neural Network Formation.
Christopher L Frank, Jasmine P Brown, Kathleen Wallace, William R Mundy, Timothy J Shafer. Toxicol Sci 2017
Christopher L Frank, Jasmine P Brown, Kathleen Wallace, William R Mundy, Timothy J Shafer. Toxicol Sci 2017
18
Editor's Highlight: Evaluation of a Microelectrode Array-Based Assay for Neural Network Ontogeny Using Training Set Chemicals.
Jasmine P Brown, Diana Hall, Christopher L Frank, Kathleen Wallace, William R Mundy, Timothy J Shafer. Toxicol Sci 2016
Jasmine P Brown, Diana Hall, Christopher L Frank, Kathleen Wallace, William R Mundy, Timothy J Shafer. Toxicol Sci 2016
21
In vitro developmental neurotoxicity (DNT) testing: relevant models and endpoints.
Anna K Bal-Price, Helena T Hogberg, Leonora Buzanska, Petros Lenas, Erwin van Vliet, Thomas Hartung. Neurotoxicology 2010
Anna K Bal-Price, Helena T Hogberg, Leonora Buzanska, Petros Lenas, Erwin van Vliet, Thomas Hartung. Neurotoxicology 2010
13
Don't judge a neuron only by its cover: neuronal function in in vitro developmental neurotoxicity testing.
Martje W G D M de Groot, Remco H S Westerink, Milou M L Dingemans. Toxicol Sci 2013
Martje W G D M de Groot, Remco H S Westerink, Milou M L Dingemans. Toxicol Sci 2013
17
Comparative human and rat neurospheres reveal species differences in chemical effects on neurodevelopmental key events.
Jenny Baumann, Kathrin Gassmann, Stefan Masjosthusmann, Denise DeBoer, Farina Bendt, Susanne Giersiefer, Ellen Fritsche. Arch Toxicol 2016
Jenny Baumann, Kathrin Gassmann, Stefan Masjosthusmann, Denise DeBoer, Farina Bendt, Susanne Giersiefer, Ellen Fritsche. Arch Toxicol 2016
13
13
Developmental neurotoxicity testing: recommendations for developing alternative methods for the screening and prioritization of chemicals.
Kevin M Crofton, William R Mundy, Pamela J Lein, Anna Bal-Price, Sandra Coecke, Andrea E M Seiler, Holger Knaut, Leonora Buzanska, Alan Goldberg. ALTEX 2011
Kevin M Crofton, William R Mundy, Pamela J Lein, Anna Bal-Price, Sandra Coecke, Andrea E M Seiler, Holger Knaut, Leonora Buzanska, Alan Goldberg. ALTEX 2011
13
Quantitative differences in developmental profiles of spontaneous activity in cortical and hippocampal cultures.
Paul Charlesworth, Ellese Cotterill, Andrew Morton, Seth G N Grant, Stephen J Eglen. Neural Dev 2015
Paul Charlesworth, Ellese Cotterill, Andrew Morton, Seth G N Grant, Stephen J Eglen. Neural Dev 2015
13
Glufosinate binds N-methyl-D-aspartate receptors and increases neuronal network activity in vitro.
Stephen R Lantz, Cina M Mack, Kathleen Wallace, Ellen F Key, Timothy J Shafer, John E Casida. Neurotoxicology 2014
Stephen R Lantz, Cina M Mack, Kathleen Wallace, Ellen F Key, Timothy J Shafer, John E Casida. Neurotoxicology 2014
19
The toxicity data landscape for environmental chemicals.
Richard Judson, Ann Richard, David J Dix, Keith Houck, Matthew Martin, Robert Kavlock, Vicki Dellarco, Tala Henry, Todd Holderman, Philip Sayre,[...]. Environ Health Perspect 2009
Richard Judson, Ann Richard, David J Dix, Keith Houck, Matthew Martin, Robert Kavlock, Vicki Dellarco, Tala Henry, Todd Holderman, Philip Sayre,[...]. Environ Health Perspect 2009
13
Application of multielectrode array (MEA) chips for the evaluation of mixtures neurotoxicity.
Bibiana Scelfo, Matteo Politi, Fabiano Reniero, Taina Palosaari, Maurice Whelan, José-Manuel Zaldívar. Toxicology 2012
Bibiana Scelfo, Matteo Politi, Fabiano Reniero, Taina Palosaari, Maurice Whelan, José-Manuel Zaldívar. Toxicology 2012
18
Putative adverse outcome pathways relevant to neurotoxicity.
Anna Bal-Price, Kevin M Crofton, Magdalini Sachana, Timothy J Shafer, Mamta Behl, Anna Forsby, Alan Hargreaves, Brigitte Landesmann, Pamela J Lein, Jochem Louisse,[...]. Crit Rev Toxicol 2015
Anna Bal-Price, Kevin M Crofton, Magdalini Sachana, Timothy J Shafer, Mamta Behl, Anna Forsby, Alan Hargreaves, Brigitte Landesmann, Pamela J Lein, Jochem Louisse,[...]. Crit Rev Toxicol 2015
13
Developmental neurotoxicity testing: a path forward.
Kevin M Crofton, William R Mundy, Timothy J Shafer. Congenit Anom (Kyoto) 2012
Kevin M Crofton, William R Mundy, Timothy J Shafer. Congenit Anom (Kyoto) 2012
13
ToxCast Chemical Landscape: Paving the Road to 21st Century Toxicology.
Ann M Richard, Richard S Judson, Keith A Houck, Christopher M Grulke, Patra Volarath, Inthirany Thillainadarajah, Chihae Yang, James Rathman, Matthew T Martin, John F Wambaugh,[...]. Chem Res Toxicol 2016
Ann M Richard, Richard S Judson, Keith A Houck, Christopher M Grulke, Patra Volarath, Inthirany Thillainadarajah, Chihae Yang, James Rathman, Matthew T Martin, John F Wambaugh,[...]. Chem Res Toxicol 2016
13
Pharmacological validation of a semi-automated in vitro hippocampal brain slice assay for assessment of seizure liability.
A Easter, T H Sharp, J-P Valentin, C E Pollard. J Pharmacol Toxicol Methods 2007
A Easter, T H Sharp, J-P Valentin, C E Pollard. J Pharmacol Toxicol Methods 2007
13
Screening the ToxCast phase II libraries for alterations in network function using cortical neurons grown on multi-well microelectrode array (mwMEA) plates.
Jenna D Strickland, Matthew T Martin, Ann M Richard, Keith A Houck, Timothy J Shafer. Arch Toxicol 2018
Jenna D Strickland, Matthew T Martin, Ann M Richard, Keith A Houck, Timothy J Shafer. Arch Toxicol 2018
16
In Vitro Screening for Seizure Liability Using Microelectrode Array Technology.
Jenifer A Bradley, Harry H Luithardt, Monica R Metea, Christopher J Strock. Toxicol Sci 2018
Jenifer A Bradley, Harry H Luithardt, Monica R Metea, Christopher J Strock. Toxicol Sci 2018
15
Neurobehavioural effects of developmental toxicity.
Philippe Grandjean, Philip J Landrigan. Lancet Neurol 2014
Philippe Grandjean, Philip J Landrigan. Lancet Neurol 2014
10
Assessment of chemical effects on neurite outgrowth in PC12 cells using high content screening.
Nicholas M Radio, Joseph M Breier, Timothy J Shafer, William R Mundy. Toxicol Sci 2008
Nicholas M Radio, Joseph M Breier, Timothy J Shafer, William R Mundy. Toxicol Sci 2008
10
Sensitivity of neuroprogenitor cells to chemical-induced apoptosis using a multiplexed assay suitable for high-throughput screening.
Ingrid Druwe, Theresa M Freudenrich, Kathleen Wallace, Timothy J Shafer, William R Mundy. Toxicology 2015
Ingrid Druwe, Theresa M Freudenrich, Kathleen Wallace, Timothy J Shafer, William R Mundy. Toxicology 2015
16
Multi-electrode array technologies for neuroscience and cardiology.
Micha E Spira, Aviad Hai. Nat Nanotechnol 2013
Micha E Spira, Aviad Hai. Nat Nanotechnol 2013
10
Long-term electrophysiological activity and pharmacological response of a human induced pluripotent stem cell-derived neuron and astrocyte co-culture.
A Odawara, Y Saitoh, A H Alhebshi, M Gotoh, I Suzuki. Biochem Biophys Res Commun 2014
A Odawara, Y Saitoh, A H Alhebshi, M Gotoh, I Suzuki. Biochem Biophys Res Commun 2014
10
Emerging roles of astrocytes in neural circuit development.
Laura E Clarke, Ben A Barres. Nat Rev Neurosci 2013
Laura E Clarke, Ben A Barres. Nat Rev Neurosci 2013
10
Application of in vitro neurotoxicity testing for regulatory purposes: Symposium III summary and research needs.
Anna K Bal-Price, Cristina Suñol, Dieter G Weiss, Erwin van Vliet, Remco H S Westerink, Lucio G Costa. Neurotoxicology 2008
Anna K Bal-Price, Cristina Suñol, Dieter G Weiss, Erwin van Vliet, Remco H S Westerink, Lucio G Costa. Neurotoxicology 2008
10
Dynamics and plasticity in developing neuronal networks in vitro.
Jaap van Pelt, Ildiko Vajda, Pieter S Wolters, Michael A Corner, Ger J A Ramakers. Prog Brain Res 2005
Jaap van Pelt, Ildiko Vajda, Pieter S Wolters, Michael A Corner, Ger J A Ramakers. Prog Brain Res 2005
10
Primary cultures from cerebral cortex and hippocampus enriched in glutamatergic and GABAergic neurons.
Ulrika Björklund, Mikael Persson, Lars Rönnbäck, Elisabeth Hansson. Neurochem Res 2010
Ulrika Björklund, Mikael Persson, Lars Rönnbäck, Elisabeth Hansson. Neurochem Res 2010
33
Development and pharmacological modulation of embryonic stem cell-derived neuronal network activity.
Sebastian Illes, Wiebke Fleischer, Mario Siebler, Hans-Peter Hartung, Marcel Dihné. Exp Neurol 2007
Sebastian Illes, Wiebke Fleischer, Mario Siebler, Hans-Peter Hartung, Marcel Dihné. Exp Neurol 2007
10
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