Baobiao Zhuo, Yuan Li, Zhengwei Li, Haihui Qin, Qingzeng Sun, Fengfei Zhang, Yang Shen, Yingchun Shi, Rong Wang. Biochem Biophys Res Commun 2015
Times Cited: 53
Times Cited: 53
Times Cited
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Understanding the Warburg effect: the metabolic requirements of cell proliferation.
Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
20
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Krushna C Patra, Qi Wang, Prashanth T Bhaskar, Luke Miller, Zebin Wang, Will Wheaton, Navdeep Chandel, Markku Laakso, William J Muller, Eric L Allen,[...]. Cancer Cell 2013
Krushna C Patra, Qi Wang, Prashanth T Bhaskar, Luke Miller, Zebin Wang, Will Wheaton, Navdeep Chandel, Markku Laakso, William J Muller, Eric L Allen,[...]. Cancer Cell 2013
18
Hexokinase 2 is a key mediator of aerobic glycolysis and promotes tumor growth in human glioblastoma multiforme.
Amparo Wolf, Sameer Agnihotri, Johann Micallef, Joydeep Mukherjee, Nesrin Sabha, Rob Cairns, Cynthia Hawkins, Abhijit Guha. J Exp Med 2011
Amparo Wolf, Sameer Agnihotri, Johann Micallef, Joydeep Mukherjee, Nesrin Sabha, Rob Cairns, Cynthia Hawkins, Abhijit Guha. J Exp Med 2011
15
Hexokinase 2-mediated Warburg effect is required for PTEN- and p53-deficiency-driven prostate cancer growth.
Lei Wang, Hua Xiong, Fengxia Wu, Yingjie Zhang, Ji Wang, Liyan Zhao, Xiaolan Guo, Li-Ju Chang, Yong Zhang, M James You,[...]. Cell Rep 2014
Lei Wang, Hua Xiong, Fengxia Wu, Yingjie Zhang, Ji Wang, Liyan Zhao, Xiaolan Guo, Li-Ju Chang, Yong Zhang, M James You,[...]. Cell Rep 2014
13
PI3K/Akt signaling in osteosarcoma.
Jian Zhang, Xiao-Hua Yu, Yi-Guo Yan, Cheng Wang, Wen-Jun Wang. Clin Chim Acta 2015
Jian Zhang, Xiao-Hua Yu, Yi-Guo Yan, Cheng Wang, Wen-Jun Wang. Clin Chim Acta 2015
13
Hexokinase II: cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria.
S P Mathupala, Y H Ko, P L Pedersen. Oncogene 2006
S P Mathupala, Y H Ko, P L Pedersen. Oncogene 2006
13
Tumor glycolysis as a target for cancer therapy: progress and prospects.
Shanmugasundaram Ganapathy-Kanniappan, Jean-Francois H Geschwind. Mol Cancer 2013
Shanmugasundaram Ganapathy-Kanniappan, Jean-Francois H Geschwind. Mol Cancer 2013
11
Isozymes of mammalian hexokinase: structure, subcellular localization and metabolic function.
John E Wilson. J Exp Biol 2003
John E Wilson. J Exp Biol 2003
11
p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation.
Keiko Kawauchi, Keigo Araki, Kei Tobiume, Nobuyuki Tanaka. Nat Cell Biol 2008
Keiko Kawauchi, Keigo Araki, Kei Tobiume, Nobuyuki Tanaka. Nat Cell Biol 2008
11
Wnt signaling directs a metabolic program of glycolysis and angiogenesis in colon cancer.
Kira T Pate, Chiara Stringari, Stephanie Sprowl-Tanio, Kehui Wang, Tara TeSlaa, Nate P Hoverter, Miriam M McQuade, Chad Garner, Michelle A Digman, Michael A Teitell,[...]. EMBO J 2014
Kira T Pate, Chiara Stringari, Stephanie Sprowl-Tanio, Kehui Wang, Tara TeSlaa, Nate P Hoverter, Miriam M McQuade, Chad Garner, Michelle A Digman, Michael A Teitell,[...]. EMBO J 2014
11
The PI3K-AKT network at the interface of oncogenic signalling and cancer metabolism.
Gerta Hoxhaj, Brendan D Manning. Nat Rev Cancer 2020
Gerta Hoxhaj, Brendan D Manning. Nat Rev Cancer 2020
11
Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis.
John G Pastorino, Nataly Shulga, Jan B Hoek. J Biol Chem 2002
John G Pastorino, Nataly Shulga, Jan B Hoek. J Biol Chem 2002
9
miR-143 regulates hexokinase 2 expression in cancer cells.
A Peschiaroli, A Giacobbe, A Formosa, E K Markert, L Bongiorno-Borbone, A J Levine, E Candi, A D'Alessandro, L Zolla, A Finazzi Agrò,[...]. Oncogene 2013
A Peschiaroli, A Giacobbe, A Formosa, E K Markert, L Bongiorno-Borbone, A J Levine, E Candi, A D'Alessandro, L Zolla, A Finazzi Agrò,[...]. Oncogene 2013
9
Is Akt the "Warburg kinase"?-Akt-energy metabolism interactions and oncogenesis.
R Brooks Robey, Nissim Hay. Semin Cancer Biol 2009
R Brooks Robey, Nissim Hay. Semin Cancer Biol 2009
9
Aerobic glycolysis: meeting the metabolic requirements of cell proliferation.
Sophia Y Lunt, Matthew G Vander Heiden. Annu Rev Cell Dev Biol 2011
Sophia Y Lunt, Matthew G Vander Heiden. Annu Rev Cell Dev Biol 2011
9
A novel miR-155/miR-143 cascade controls glycolysis by regulating hexokinase 2 in breast cancer cells.
Shuai Jiang, Ling-Fei Zhang, Hong-Wei Zhang, Song Hu, Ming-Hua Lu, Sheng Liang, Biao Li, Yong Li, Dangsheng Li, En-Duo Wang,[...]. EMBO J 2012
Shuai Jiang, Ling-Fei Zhang, Hong-Wei Zhang, Song Hu, Ming-Hua Lu, Sheng Liang, Biao Li, Yong Li, Dangsheng Li, En-Duo Wang,[...]. EMBO J 2012
9
MiR-199a-5p is negatively associated with malignancies and regulates glycolysis and lactate production by targeting hexokinase 2 in liver cancer.
Weijie Guo, Zhaoping Qiu, Zhichao Wang, Qifeng Wang, Ning Tan, Taoyang Chen, Zhiao Chen, Shenglin Huang, Jianren Gu, Jinjun Li,[...]. Hepatology 2015
Weijie Guo, Zhaoping Qiu, Zhichao Wang, Qifeng Wang, Ning Tan, Taoyang Chen, Zhiao Chen, Shenglin Huang, Jianren Gu, Jinjun Li,[...]. Hepatology 2015
9
MicroRNA-143 down-regulates Hexokinase 2 in colon cancer cells.
Lea H Gregersen, Anders Jacobsen, Lisa B Frankel, Jiayu Wen, Anders Krogh, Anders H Lund. BMC Cancer 2012
Lea H Gregersen, Anders Jacobsen, Lisa B Frankel, Jiayu Wen, Anders Krogh, Anders H Lund. BMC Cancer 2012
9
Akt stimulates aerobic glycolysis in cancer cells.
Rebecca L Elstrom, Daniel E Bauer, Monica Buzzai, Robyn Karnauskas, Marian H Harris, David R Plas, Hongming Zhuang, Ryan M Cinalli, Abass Alavi, Charles M Rudin,[...]. Cancer Res 2004
Rebecca L Elstrom, Daniel E Bauer, Monica Buzzai, Robyn Karnauskas, Marian H Harris, David R Plas, Hongming Zhuang, Ryan M Cinalli, Abass Alavi, Charles M Rudin,[...]. Cancer Res 2004
9
The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression.
Fabiana Schwartzenberg-Bar-Yoseph, Michal Armoni, Eddy Karnieli. Cancer Res 2004
Fabiana Schwartzenberg-Bar-Yoseph, Michal Armoni, Eddy Karnieli. Cancer Res 2004
9
A lentiviral sponge for miRNA-21 diminishes aerobic glycolysis in bladder cancer T24 cells via the PTEN/PI3K/AKT/mTOR axis.
Xiao Yang, Yidong Cheng, Pengchao Li, Jun Tao, Xiaheng Deng, Xiaolei Zhang, Min Gu, Qiang Lu, Changjun Yin. Tumour Biol 2015
Xiao Yang, Yidong Cheng, Pengchao Li, Jun Tao, Xiaheng Deng, Xiaolei Zhang, Min Gu, Qiang Lu, Changjun Yin. Tumour Biol 2015
9
Regulation of GLUT1 gene transcription by the serine/threonine kinase Akt1.
A Barthel, S T Okino, J Liao, K Nakatani, J Li, J P Whitlock, R A Roth. J Biol Chem 1999
A Barthel, S T Okino, J Liao, K Nakatani, J Li, J P Whitlock, R A Roth. J Biol Chem 1999
9
Osteosarcoma incidence and survival rates from 1973 to 2004: data from the Surveillance, Epidemiology, and End Results Program.
Lisa Mirabello, Rebecca J Troisi, Sharon A Savage. Cancer 2009
Lisa Mirabello, Rebecca J Troisi, Sharon A Savage. Cancer 2009
9
9
Hexokinase II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy.
D J Roberts, S Miyamoto. Cell Death Differ 2015
D J Roberts, S Miyamoto. Cell Death Differ 2015
9
Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak.
Nathan Majewski, Veronique Nogueira, Prashanth Bhaskar, Platina E Coy, Jennifer E Skeen, Kathrin Gottlob, Navdeep S Chandel, Craig B Thompson, R Brooks Robey, Nissim Hay. Mol Cell 2004
Nathan Majewski, Veronique Nogueira, Prashanth Bhaskar, Platina E Coy, Jennifer E Skeen, Kathrin Gottlob, Navdeep S Chandel, Craig B Thompson, R Brooks Robey, Nissim Hay. Mol Cell 2004
7
Targeting VDAC-bound hexokinase II: a promising approach for concomitant anti-cancer therapy.
George S Krasnov, Alexey A Dmitriev, Valentina A Lakunina, Alexander A Kirpiy, Anna V Kudryavtseva. Expert Opin Ther Targets 2013
George S Krasnov, Alexey A Dmitriev, Valentina A Lakunina, Alexander A Kirpiy, Anna V Kudryavtseva. Expert Opin Ther Targets 2013
7
Phosphorylation and activation of heart 6-phosphofructo-2-kinase by protein kinase B and other protein kinases of the insulin signaling cascades.
J Deprez, D Vertommen, D R Alessi, L Hue, M H Rider. J Biol Chem 1997
J Deprez, D Vertommen, D R Alessi, L Hue, M H Rider. J Biol Chem 1997
7
MUC16-mediated activation of mTOR and c-Myc reprograms pancreatic cancer metabolism.
Surendra K Shukla, Venugopal Gunda, Jaime Abrego, Dhanya Haridas, Anusha Mishra, Joshua Souchek, Nina V Chaika, Fang Yu, Aaron R Sasson, Audrey J Lazenby,[...]. Oncotarget 2015
Surendra K Shukla, Venugopal Gunda, Jaime Abrego, Dhanya Haridas, Anusha Mishra, Joshua Souchek, Nina V Chaika, Fang Yu, Aaron R Sasson, Audrey J Lazenby,[...]. Oncotarget 2015
7
Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells.
Jihye Yun, Carlo Rago, Ian Cheong, Ray Pagliarini, Philipp Angenendt, Harith Rajagopalan, Kerstin Schmidt, James K V Willson, Sandy Markowitz, Shibin Zhou,[...]. Science 2009
Jihye Yun, Carlo Rago, Ian Cheong, Ray Pagliarini, Philipp Angenendt, Harith Rajagopalan, Kerstin Schmidt, James K V Willson, Sandy Markowitz, Shibin Zhou,[...]. Science 2009
7
Tumour-associated mutant p53 drives the Warburg effect.
Cen Zhang, Juan Liu, Yingjian Liang, Rui Wu, Yuhan Zhao, Xuehui Hong, Meihua Lin, Haiyang Yu, Lianxin Liu, Arnold J Levine,[...]. Nat Commun 2013
Cen Zhang, Juan Liu, Yingjian Liang, Rui Wu, Yuhan Zhao, Xuehui Hong, Meihua Lin, Haiyang Yu, Lianxin Liu, Arnold J Levine,[...]. Nat Commun 2013
7
Signaling through the Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Axis Is Responsible for Aerobic Glycolysis mediated by Glucose Transporter in Epidermal Growth Factor Receptor (EGFR)-mutated Lung Adenocarcinoma.
Hideki Makinoshima, Masahiro Takita, Koichi Saruwatari, Shigeki Umemura, Yuuki Obata, Genichiro Ishii, Shingo Matsumoto, Eri Sugiyama, Atsushi Ochiai, Ryo Abe,[...]. J Biol Chem 2015
Hideki Makinoshima, Masahiro Takita, Koichi Saruwatari, Shigeki Umemura, Yuuki Obata, Genichiro Ishii, Shingo Matsumoto, Eri Sugiyama, Atsushi Ochiai, Ryo Abe,[...]. J Biol Chem 2015
7
c-Myc transactivation of LDH-A: implications for tumor metabolism and growth.
H Shim, C Dolde, B C Lewis, C S Wu, G Dang, R A Jungmann, R Dalla-Favera, C V Dang. Proc Natl Acad Sci U S A 1997
H Shim, C Dolde, B C Lewis, C S Wu, G Dang, R A Jungmann, R Dalla-Favera, C V Dang. Proc Natl Acad Sci U S A 1997
7
TIGAR, a p53-inducible regulator of glycolysis and apoptosis.
Karim Bensaad, Atsushi Tsuruta, Mary A Selak, M Nieves Calvo Vidal, Katsunori Nakano, Ramon Bartrons, Eyal Gottlieb, Karen H Vousden. Cell 2006
Karim Bensaad, Atsushi Tsuruta, Mary A Selak, M Nieves Calvo Vidal, Katsunori Nakano, Ramon Bartrons, Eyal Gottlieb, Karen H Vousden. Cell 2006
7
AKT-mediated enhanced aerobic glycolysis causes acquired radioresistance by human tumor cells.
Tsutomu Shimura, Naoto Noma, Yui Sano, Yasushi Ochiai, Toshiyuki Oikawa, Manabu Fukumoto, Naoki Kunugita. Radiother Oncol 2014
Tsutomu Shimura, Naoto Noma, Yui Sano, Yasushi Ochiai, Toshiyuki Oikawa, Manabu Fukumoto, Naoki Kunugita. Radiother Oncol 2014
7
Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism.
Haoqiang Ying, Alec C Kimmelman, Costas A Lyssiotis, Sujun Hua, Gerald C Chu, Eliot Fletcher-Sananikone, Jason W Locasale, Jaekyoung Son, Hailei Zhang, Jonathan L Coloff,[...]. Cell 2012
Haoqiang Ying, Alec C Kimmelman, Costas A Lyssiotis, Sujun Hua, Gerald C Chu, Eliot Fletcher-Sananikone, Jason W Locasale, Jaekyoung Son, Hailei Zhang, Jonathan L Coloff,[...]. Cell 2012
7
p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase.
Peng Jiang, Wenjing Du, Xingwu Wang, Anthony Mancuso, Xiang Gao, Mian Wu, Xiaolu Yang. Nat Cell Biol 2011
Peng Jiang, Wenjing Du, Xingwu Wang, Anthony Mancuso, Xiang Gao, Mian Wu, Xiaolu Yang. Nat Cell Biol 2011
7
Hexokinase-2 bound to mitochondria: cancer's stygian link to the "Warburg Effect" and a pivotal target for effective therapy.
Saroj P Mathupala, Young H Ko, Peter L Pedersen. Semin Cancer Biol 2009
Saroj P Mathupala, Young H Ko, Peter L Pedersen. Semin Cancer Biol 2009
7
Long non-coding RNA UCA1 promotes glycolysis by upregulating hexokinase 2 through the mTOR-STAT3/microRNA143 pathway.
Zhengkun Li, Xu Li, Shouzhen Wu, Mei Xue, Wei Chen. Cancer Sci 2014
Zhengkun Li, Xu Li, Shouzhen Wu, Mei Xue, Wei Chen. Cancer Sci 2014
7
Akt inhibition promotes hexokinase 2 redistribution and glucose uptake in cancer cells.
Catherine L Neary, John G Pastorino. J Cell Physiol 2013
Catherine L Neary, John G Pastorino. J Cell Physiol 2013
11
Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase.
K Gottlob, N Majewski, S Kennedy, E Kandel, R B Robey, N Hay. Genes Dev 2001
K Gottlob, N Majewski, S Kennedy, E Kandel, R B Robey, N Hay. Genes Dev 2001
7
Inhibition of glycolytic enzyme hexokinase II (HK2) suppresses lung tumor growth.
Huanan Wang, Lei Wang, Yingjie Zhang, Ji Wang, Yibin Deng, Degui Lin. Cancer Cell Int 2016
Huanan Wang, Lei Wang, Yingjie Zhang, Ji Wang, Yibin Deng, Degui Lin. Cancer Cell Int 2016
7
Otto Warburg's contributions to current concepts of cancer metabolism.
Willem H Koppenol, Patricia L Bounds, Chi V Dang. Nat Rev Cancer 2011
Willem H Koppenol, Patricia L Bounds, Chi V Dang. Nat Rev Cancer 2011
7
Targeting glucose metabolism for cancer therapy.
Robert B Hamanaka, Navdeep S Chandel. J Exp Med 2012
Robert B Hamanaka, Navdeep S Chandel. J Exp Med 2012
5
Glucose catabolism in cancer cells: amplification of the gene encoding type II hexokinase.
A Rempel, S P Mathupala, C A Griffin, A L Hawkins, P L Pedersen. Cancer Res 1996
A Rempel, S P Mathupala, C A Griffin, A L Hawkins, P L Pedersen. Cancer Res 1996
5
MicroRNA-29B (mir-29b) regulates the Warburg effect in ovarian cancer by targeting AKT2 and AKT3.
Yue Teng, Yan Zhang, Kai Qu, Xinyuan Yang, Jing Fu, Wei Chen, Xu Li. Oncotarget 2015
Yue Teng, Yan Zhang, Kai Qu, Xinyuan Yang, Jing Fu, Wei Chen, Xu Li. Oncotarget 2015
6
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.