Tobias Wauer, Michal Simicek, Alexander Schubert, David Komander. Nature 2015
Times Cited: 260
Times Cited: 260
Times Cited
Times Co-cited
Similarity
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy.
Michael Lazarou, Danielle A Sliter, Lesley A Kane, Shireen A Sarraf, Chunxin Wang, Jonathon L Burman, Dionisia P Sideris, Adam I Fogel, Richard J Youle. Nature 2015
Michael Lazarou, Danielle A Sliter, Lesley A Kane, Shireen A Sarraf, Chunxin Wang, Jonathon L Burman, Dionisia P Sideris, Adam I Fogel, Richard J Youle. Nature 2015
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Ubiquitin is phosphorylated by PINK1 to activate parkin.
Fumika Koyano, Kei Okatsu, Hidetaka Kosako, Yasushi Tamura, Etsu Go, Mayumi Kimura, Yoko Kimura, Hikaru Tsuchiya, Hidehito Yoshihara, Takatsugu Hirokawa,[...]. Nature 2014
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PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity.
Lesley A Kane, Michael Lazarou, Adam I Fogel, Yan Li, Koji Yamano, Shireen A Sarraf, Soojay Banerjee, Richard J Youle. J Cell Biol 2014
Lesley A Kane, Michael Lazarou, Adam I Fogel, Yan Li, Koji Yamano, Shireen A Sarraf, Soojay Banerjee, Richard J Youle. J Cell Biol 2014
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Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis.
Alban Ordureau, Shireen A Sarraf, David M Duda, Jin-Mi Heo, Mark P Jedrychowski, Vladislav O Sviderskiy, Jennifer L Olszewski, James T Koerber, Tiao Xie, Sean A Beausoleil,[...]. Mol Cell 2014
Alban Ordureau, Shireen A Sarraf, David M Duda, Jin-Mi Heo, Mark P Jedrychowski, Vladislav O Sviderskiy, Jennifer L Olszewski, James T Koerber, Tiao Xie, Sean A Beausoleil,[...]. Mol Cell 2014
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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy.
Derek Narendra, Atsushi Tanaka, Der-Fen Suen, Richard J Youle. J Cell Biol 2008
Derek Narendra, Atsushi Tanaka, Der-Fen Suen, Richard J Youle. J Cell Biol 2008
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Mechanism of parkin activation by PINK1.
Christina Gladkova, Sarah L Maslen, J Mark Skehel, David Komander. Nature 2018
Christina Gladkova, Sarah L Maslen, J Mark Skehel, David Komander. Nature 2018
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Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65.
Agne Kazlauskaite, Chandana Kondapalli, Robert Gourlay, David G Campbell, Maria Stella Ritorto, Kay Hofmann, Dario R Alessi, Axel Knebel, Matthias Trost, Miratul M K Muqit. Biochem J 2014
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PINK1 is selectively stabilized on impaired mitochondria to activate Parkin.
Derek P Narendra, Seok Min Jin, Atsushi Tanaka, Der-Fen Suen, Clement A Gautier, Jie Shen, Mark R Cookson, Richard J Youle. PLoS Biol 2010
Derek P Narendra, Seok Min Jin, Atsushi Tanaka, Der-Fen Suen, Clement A Gautier, Jie Shen, Mark R Cookson, Richard J Youle. PLoS Biol 2010
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PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65.
Chandana Kondapalli, Agne Kazlauskaite, Ning Zhang, Helen I Woodroof, David G Campbell, Robert Gourlay, Lynn Burchell, Helen Walden, Thomas J Macartney, Maria Deak,[...]. Open Biol 2012
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Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
Shireen A Sarraf, Malavika Raman, Virginia Guarani-Pereira, Mathew E Sowa, Edward L Huttlin, Steven P Gygi, J Wade Harper. Nature 2013
Shireen A Sarraf, Malavika Raman, Virginia Guarani-Pereira, Mathew E Sowa, Edward L Huttlin, Steven P Gygi, J Wade Harper. Nature 2013
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The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy.
Jin-Mi Heo, Alban Ordureau, Joao A Paulo, Jesse Rinehart, J Wade Harper. Mol Cell 2015
Jin-Mi Heo, Alban Ordureau, Joao A Paulo, Jesse Rinehart, J Wade Harper. Mol Cell 2015
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Mechanism of parkin activation by phosphorylation.
Véronique Sauvé, George Sung, Naoto Soya, Guennadi Kozlov, Nina Blaimschein, Lis Schwartz Miotto, Jean-François Trempe, Gergely L Lukacs, Kalle Gehring. Nat Struct Mol Biol 2018
Véronique Sauvé, George Sung, Naoto Soya, Guennadi Kozlov, Nina Blaimschein, Lis Schwartz Miotto, Jean-François Trempe, Gergely L Lukacs, Kalle Gehring. Nat Struct Mol Biol 2018
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Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation.
Agne Kazlauskaite, R Julio Martínez-Torres, Scott Wilkie, Atul Kumar, Julien Peltier, Alba Gonzalez, Clare Johnson, Jinwei Zhang, Anthony G Hope, Mark Peggie,[...]. EMBO Rep 2015
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PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy.
Noriyuki Matsuda, Shigeto Sato, Kahori Shiba, Kei Okatsu, Keiko Saisho, Clement A Gautier, Yu-Shin Sou, Shinji Saiki, Sumihiro Kawajiri, Fumiaki Sato,[...]. J Cell Biol 2010
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A Ubl/ubiquitin switch in the activation of Parkin.
Véronique Sauvé, Asparouh Lilov, Marjan Seirafi, Marta Vranas, Shafqat Rasool, Guennadi Kozlov, Tara Sprules, Jimin Wang, Jean-François Trempe, Kalle Gehring. EMBO J 2015
Véronique Sauvé, Asparouh Lilov, Marjan Seirafi, Marta Vranas, Shafqat Rasool, Guennadi Kozlov, Tara Sprules, Jimin Wang, Jean-François Trempe, Kalle Gehring. EMBO J 2015
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Structure of parkin reveals mechanisms for ubiquitin ligase activation.
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Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism.
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Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin.
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Structure of the human Parkin ligase domain in an autoinhibited state.
Tobias Wauer, David Komander. EMBO J 2013
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Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells.
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The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy.
Baris Bingol, Joy S Tea, Lilian Phu, Mike Reichelt, Corey E Bakalarski, Qinghua Song, Oded Foreman, Donald S Kirkpatrick, Morgan Sheng. Nature 2014
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Parkin and PINK1 mitigate STING-induced inflammation.
Danielle A Sliter, Jennifer Martinez, Ling Hao, Xi Chen, Nuo Sun, Tara D Fischer, Jonathon L Burman, Yan Li, Zhe Zhang, Derek P Narendra,[...]. Nature 2018
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The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's disease.
Alicia M Pickrell, Richard J Youle. Neuron 2015
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Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria.
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Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand.
Thomas G McWilliams, Alan R Prescott, Lambert Montava-Garriga, Graeme Ball, François Singh, Erica Barini, Miratul M K Muqit, Simon P Brooks, Ian G Ganley. Cell Metab 2018
Thomas G McWilliams, Alan R Prescott, Lambert Montava-Garriga, Graeme Ball, François Singh, Erica Barini, Miratul M K Muqit, Simon P Brooks, Ian G Ganley. Cell Metab 2018
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Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy.
Jose Norberto S Vargas, Chunxin Wang, Eric Bunker, Ling Hao, Dragan Maric, Giampietro Schiavo, Felix Randow, Richard J Youle. Mol Cell 2019
Jose Norberto S Vargas, Chunxin Wang, Eric Bunker, Ling Hao, Dragan Maric, Giampietro Schiavo, Felix Randow, Richard J Youle. Mol Cell 2019
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Phosphorylated ubiquitin chain is the genuine Parkin receptor.
Kei Okatsu, Fumika Koyano, Mayumi Kimura, Hidetaka Kosako, Yasushi Saeki, Keiji Tanaka, Noriyuki Matsuda. J Cell Biol 2015
Kei Okatsu, Fumika Koyano, Mayumi Kimura, Hidetaka Kosako, Yasushi Saeki, Keiji Tanaka, Noriyuki Matsuda. J Cell Biol 2015
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PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy.
Kahori Shiba-Fukushima, Yuzuru Imai, Shigeharu Yoshida, Yasushi Ishihama, Tomoko Kanao, Shigeto Sato, Nobutaka Hattori. Sci Rep 2012
Kahori Shiba-Fukushima, Yuzuru Imai, Shigeharu Yoshida, Yasushi Ishihama, Tomoko Kanao, Shigeto Sato, Nobutaka Hattori. Sci Rep 2012
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Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL.
Seok Min Jin, Michael Lazarou, Chunxin Wang, Lesley A Kane, Derek P Narendra, Richard J Youle. J Cell Biol 2010
Seok Min Jin, Michael Lazarou, Chunxin Wang, Lesley A Kane, Derek P Narendra, Richard J Youle. J Cell Biol 2010
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Global Landscape and Dynamics of Parkin and USP30-Dependent Ubiquitylomes in iNeurons during Mitophagic Signaling.
Alban Ordureau, Joao A Paulo, Jiuchun Zhang, Heeseon An, Kirby N Swatek, Joe R Cannon, Qiaoqiao Wan, David Komander, J Wade Harper. Mol Cell 2020
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Building and decoding ubiquitin chains for mitophagy.
J Wade Harper, Alban Ordureau, Jin-Mi Heo. Nat Rev Mol Cell Biol 2018
J Wade Harper, Alban Ordureau, Jin-Mi Heo. Nat Rev Mol Cell Biol 2018
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Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin.
Atsushi Tanaka, Megan M Cleland, Shan Xu, Derek P Narendra, Der-Fen Suen, Mariusz Karbowski, Richard J Youle. J Cell Biol 2010
Atsushi Tanaka, Megan M Cleland, Shan Xu, Derek P Narendra, Der-Fen Suen, Mariusz Karbowski, Richard J Youle. J Cell Biol 2010
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PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1.
Sven Geisler, Kira M Holmström, Diana Skujat, Fabienne C Fiesel, Oliver C Rothfuss, Philipp J Kahle, Wolfdieter Springer. Nat Cell Biol 2010
Sven Geisler, Kira M Holmström, Diana Skujat, Fabienne C Fiesel, Oliver C Rothfuss, Philipp J Kahle, Wolfdieter Springer. Nat Cell Biol 2010
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Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis.
Tobias Wauer, Kirby N Swatek, Jane L Wagstaff, Christina Gladkova, Jonathan N Pruneda, Martin A Michel, Malte Gersch, Christopher M Johnson, Stefan M V Freund, David Komander. EMBO J 2015
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Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Atul Kumar, Jacob D Aguirre, Tara E C Condos, R Julio Martinez-Torres, Viduth K Chaugule, Rachel Toth, Ramasubramanian Sundaramoorthy, Pascal Mercier, Axel Knebel, Donald E Spratt,[...]. EMBO J 2015
Atul Kumar, Jacob D Aguirre, Tara E C Condos, R Julio Martinez-Torres, Viduth K Chaugule, Rachel Toth, Ramasubramanian Sundaramoorthy, Pascal Mercier, Axel Knebel, Donald E Spratt,[...]. EMBO J 2015
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PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria.
Kei Okatsu, Toshihiko Oka, Masahiro Iguchi, Kenji Imamura, Hidetaka Kosako, Naoki Tani, Mayumi Kimura, Etsu Go, Fumika Koyano, Manabu Funayama,[...]. Nat Commun 2012
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Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases.
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Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation.
Yvette C Wong, Erika L F Holzbaur. Proc Natl Acad Sci U S A 2014
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A regulatory signaling loop comprising the PGAM5 phosphatase and CK2 controls receptor-mediated mitophagy.
Guo Chen, Zhe Han, Du Feng, Yanfang Chen, Linbo Chen, Hao Wu, Li Huang, Changqian Zhou, Xiangyu Cai, Changying Fu,[...]. Mol Cell 2014
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PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.
Cristofol Vives-Bauza, Chun Zhou, Yong Huang, Mei Cui, Rosa L A de Vries, Jiho Kim, Jessica May, Maja Aleksandra Tocilescu, Wencheng Liu, Han Seok Ko,[...]. Proc Natl Acad Sci U S A 2010
Cristofol Vives-Bauza, Chun Zhou, Yong Huang, Mei Cui, Rosa L A de Vries, Jiho Kim, Jessica May, Maja Aleksandra Tocilescu, Wencheng Liu, Han Seok Ko,[...]. Proc Natl Acad Sci U S A 2010
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A new pathway for mitochondrial quality control: mitochondrial-derived vesicles.
Ayumu Sugiura, Gian-Luca McLelland, Edward A Fon, Heidi M McBride. EMBO J 2014
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Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics.
Alban Ordureau, Joao A Paulo, Wei Zhang, Tim Ahfeldt, Jiuchun Zhang, Erin F Cohn, Zhonggang Hou, Jin-Mi Heo, Lee L Rubin, Sachdev S Sidhu,[...]. Mol Cell 2018
Alban Ordureau, Joao A Paulo, Wei Zhang, Tim Ahfeldt, Jiuchun Zhang, Erin F Cohn, Zhonggang Hou, Jin-Mi Heo, Lee L Rubin, Sachdev S Sidhu,[...]. Mol Cell 2018
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PINK1 autophosphorylation is required for ubiquitin recognition.
Shafqat Rasool, Naoto Soya, Luc Truong, Nathalie Croteau, Gergely L Lukacs, Jean-François Trempe. EMBO Rep 2018
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Dynamic Regulation of Mitochondrial Import by the Ubiquitin System.
Lilian Phu, Christopher M Rose, Joy S Tea, Christopher E Wall, Erik Verschueren, Tommy K Cheung, Donald S Kirkpatrick, Baris Bingol. Mol Cell 2020
Lilian Phu, Christopher M Rose, Joy S Tea, Christopher E Wall, Erik Verschueren, Tommy K Cheung, Donald S Kirkpatrick, Baris Bingol. Mol Cell 2020
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Mechanism and regulation of the Lys6-selective deubiquitinase USP30.
Malte Gersch, Christina Gladkova, Alexander F Schubert, Martin A Michel, Sarah Maslen, David Komander. Nat Struct Mol Biol 2017
Malte Gersch, Christina Gladkova, Alexander F Schubert, Martin A Michel, Sarah Maslen, David Komander. Nat Struct Mol Biol 2017
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Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy.
Alban Ordureau, Jin-Mi Heo, David M Duda, Joao A Paulo, Jennifer L Olszewski, David Yanishevski, Jesse Rinehart, Brenda A Schulman, J Wade Harper. Proc Natl Acad Sci U S A 2015
Alban Ordureau, Jin-Mi Heo, David M Duda, Joao A Paulo, Jennifer L Olszewski, David Yanishevski, Jesse Rinehart, Brenda A Schulman, J Wade Harper. Proc Natl Acad Sci U S A 2015
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Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment.
Andrew W Greene, Karl Grenier, Miguel A Aguileta, Stephanie Muise, Rasoul Farazifard, M Emdadul Haque, Heidi M McBride, David S Park, Edward A Fon. EMBO Rep 2012
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17
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.