Yoong Wearn Lim, Lionel A Sanz, Xiaoqin Xu, Stella R Hartono, Frédéric Chédin. Elife 2015
Times Cited: 95
Times Cited: 95
Times Cited
Times Co-cited
Similarity
R-loop formation is a distinctive characteristic of unmethylated human CpG island promoters.
Paul A Ginno, Paul L Lott, Holly C Christensen, Ian Korf, Frédéric Chédin. Mol Cell 2012
Paul A Ginno, Paul L Lott, Holly C Christensen, Ian Korf, Frédéric Chédin. Mol Cell 2012
37
R loops: new modulators of genome dynamics and function.
José M Santos-Pereira, Andrés Aguilera. Nat Rev Genet 2015
José M Santos-Pereira, Andrés Aguilera. Nat Rev Genet 2015
31
Human senataxin resolves RNA/DNA hybrids formed at transcriptional pause sites to promote Xrn2-dependent termination.
Konstantina Skourti-Stathaki, Nicholas J Proudfoot, Natalia Gromak. Mol Cell 2011
Konstantina Skourti-Stathaki, Nicholas J Proudfoot, Natalia Gromak. Mol Cell 2011
30
Prevalent, Dynamic, and Conserved R-Loop Structures Associate with Specific Epigenomic Signatures in Mammals.
Lionel A Sanz, Stella R Hartono, Yoong Wearn Lim, Sandra Steyaert, Aparna Rajpurkar, Paul A Ginno, Xiaoqin Xu, Frédéric Chédin. Mol Cell 2016
Lionel A Sanz, Stella R Hartono, Yoong Wearn Lim, Sandra Steyaert, Aparna Rajpurkar, Paul A Ginno, Xiaoqin Xu, Frédéric Chédin. Mol Cell 2016
30
Loss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis.
Aziz El Hage, Sarah L French, Ann L Beyer, David Tollervey. Genes Dev 2010
Aziz El Hage, Sarah L French, Ann L Beyer, David Tollervey. Genes Dev 2010
29
GC skew at the 5' and 3' ends of human genes links R-loop formation to epigenetic regulation and transcription termination.
Paul A Ginno, Yoong Wearn Lim, Paul L Lott, Ian Korf, Frédéric Chédin. Genome Res 2013
Paul A Ginno, Yoong Wearn Lim, Paul L Lott, Ian Korf, Frédéric Chédin. Genome Res 2013
28
R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells.
Kefei Yu, Frederic Chedin, Chih-Lin Hsieh, Thomas E Wilson, Michael R Lieber. Nat Immunol 2003
Kefei Yu, Frederic Chedin, Chih-Lin Hsieh, Thomas E Wilson, Michael R Lieber. Nat Immunol 2003
26
25
R loops: from transcription byproducts to threats to genome stability.
Andrés Aguilera, Tatiana García-Muse. Mol Cell 2012
Andrés Aguilera, Tatiana García-Muse. Mol Cell 2012
24
Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection.
Yanick J Crow, Andrea Leitch, Bruce E Hayward, Anna Garner, Rekha Parmar, Elen Griffith, Manir Ali, Colin Semple, Jean Aicardi, Riyana Babul-Hirji,[...]. Nat Genet 2006
Yanick J Crow, Andrea Leitch, Bruce E Hayward, Anna Garner, Rekha Parmar, Elen Griffith, Manir Ali, Colin Semple, Jean Aicardi, Riyana Babul-Hirji,[...]. Nat Genet 2006
24
Transcription-coupled nucleotide excision repair factors promote R-loop-induced genome instability.
Julie Sollier, Caroline Townsend Stork, María L García-Rubio, Renee D Paulsen, Andrés Aguilera, Karlene A Cimprich. Mol Cell 2014
Julie Sollier, Caroline Townsend Stork, María L García-Rubio, Renee D Paulsen, Andrés Aguilera, Karlene A Cimprich. Mol Cell 2014
24
S1-DRIP-seq identifies high expression and polyA tracts as major contributors to R-loop formation.
Lamia Wahba, Lorenzo Costantino, Frederick J Tan, Anjali Zimmer, Douglas Koshland. Genes Dev 2016
Lamia Wahba, Lorenzo Costantino, Frederick J Tan, Anjali Zimmer, Douglas Koshland. Genes Dev 2016
24
Cotranscriptionally formed DNA:RNA hybrids mediate transcription elongation impairment and transcription-associated recombination.
Pablo Huertas, Andrés Aguilera. Mol Cell 2003
Pablo Huertas, Andrés Aguilera. Mol Cell 2003
23
Genome-wide distribution of RNA-DNA hybrids identifies RNase H targets in tRNA genes, retrotransposons and mitochondria.
Aziz El Hage, Shaun Webb, Alastair Kerr, David Tollervey. PLoS Genet 2014
Aziz El Hage, Shaun Webb, Alastair Kerr, David Tollervey. PLoS Genet 2014
22
RNase H and multiple RNA biogenesis factors cooperate to prevent RNA:DNA hybrids from generating genome instability.
Lamia Wahba, Jeremy D Amon, Douglas Koshland, Milena Vuica-Ross. Mol Cell 2011
Lamia Wahba, Jeremy D Amon, Douglas Koshland, Milena Vuica-Ross. Mol Cell 2011
22
R-loops induce repressive chromatin marks over mammalian gene terminators.
Konstantina Skourti-Stathaki, Kinga Kamieniarz-Gdula, Nicholas J Proudfoot. Nature 2014
Konstantina Skourti-Stathaki, Kinga Kamieniarz-Gdula, Nicholas J Proudfoot. Nature 2014
22
Breaking bad: R-loops and genome integrity.
Julie Sollier, Karlene A Cimprich. Trends Cell Biol 2015
Julie Sollier, Karlene A Cimprich. Trends Cell Biol 2015
21
Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development.
Martin A M Reijns, Björn Rabe, Rachel E Rigby, Pleasantine Mill, Katy R Astell, Laura A Lettice, Shelagh Boyle, Andrea Leitch, Margaret Keighren, Fiona Kilanowski,[...]. Cell 2012
Martin A M Reijns, Björn Rabe, Rachel E Rigby, Pleasantine Mill, Katy R Astell, Laura A Lettice, Shelagh Boyle, Andrea Leitch, Margaret Keighren, Fiona Kilanowski,[...]. Cell 2012
21
R-loop-mediated genomic instability is caused by impairment of replication fork progression.
Wenjian Gan, Zhishuang Guan, Jie Liu, Ting Gui, Keng Shen, James L Manley, Xialu Li. Genes Dev 2011
Wenjian Gan, Zhishuang Guan, Jie Liu, Ting Gui, Keng Shen, James L Manley, Xialu Li. Genes Dev 2011
21
BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2.
Vaibhav Bhatia, Sonia I Barroso, María L García-Rubio, Emanuela Tumini, Emilia Herrera-Moyano, Andrés Aguilera. Nature 2014
Vaibhav Bhatia, Sonia I Barroso, María L García-Rubio, Emanuela Tumini, Emilia Herrera-Moyano, Andrés Aguilera. Nature 2014
21
Genome-wide profiling of yeast DNA:RNA hybrid prone sites with DRIP-chip.
Yujia A Chan, Maria J Aristizabal, Phoebe Y T Lu, Zongli Luo, Akil Hamza, Michael S Kobor, Peter C Stirling, Philip Hieter. PLoS Genet 2014
Yujia A Chan, Maria J Aristizabal, Phoebe Y T Lu, Zongli Luo, Akil Hamza, Michael S Kobor, Peter C Stirling, Philip Hieter. PLoS Genet 2014
20
R loops regulate promoter-proximal chromatin architecture and cellular differentiation.
Poshen B Chen, Hsiuyi V Chen, Diwash Acharya, Oliver J Rando, Thomas G Fazzio. Nat Struct Mol Biol 2015
Poshen B Chen, Hsiuyi V Chen, Diwash Acharya, Oliver J Rando, Thomas G Fazzio. Nat Struct Mol Biol 2015
21
A double-edged sword: R loops as threats to genome integrity and powerful regulators of gene expression.
Konstantina Skourti-Stathaki, Nicholas J Proudfoot. Genes Dev 2014
Konstantina Skourti-Stathaki, Nicholas J Proudfoot. Genes Dev 2014
20
Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response.
Gillian I Rice, Jacquelyn Bond, Aruna Asipu, Rebecca L Brunette, Iain W Manfield, Ian M Carr, Jonathan C Fuller, Richard M Jackson, Teresa Lamb, Tracy A Briggs,[...]. Nat Genet 2009
Gillian I Rice, Jacquelyn Bond, Aruna Asipu, Rebecca L Brunette, Iain W Manfield, Ian M Carr, Jonathan C Fuller, Richard M Jackson, Teresa Lamb, Tracy A Briggs,[...]. Nat Genet 2009
20
Defective removal of ribonucleotides from DNA promotes systemic autoimmunity.
Claudia Günther, Barbara Kind, Martin A M Reijns, Nicole Berndt, Manuel Martinez-Bueno, Christine Wolf, Victoria Tüngler, Osvaldo Chara, Young Ae Lee, Norbert Hübner,[...]. J Clin Invest 2015
Claudia Günther, Barbara Kind, Martin A M Reijns, Nicole Berndt, Manuel Martinez-Bueno, Christine Wolf, Victoria Tüngler, Osvaldo Chara, Young Ae Lee, Norbert Hübner,[...]. J Clin Invest 2015
18
BRCA1 recruitment to transcriptional pause sites is required for R-loop-driven DNA damage repair.
Elodie Hatchi, Konstantina Skourti-Stathaki, Steffen Ventz, Luca Pinello, Angela Yen, Kinga Kamieniarz-Gdula, Stoil Dimitrov, Shailja Pathania, Kristine M McKinney, Matthew L Eaton,[...]. Mol Cell 2015
Elodie Hatchi, Konstantina Skourti-Stathaki, Steffen Ventz, Luca Pinello, Angela Yen, Kinga Kamieniarz-Gdula, Stoil Dimitrov, Shailja Pathania, Kristine M McKinney, Matthew L Eaton,[...]. Mol Cell 2015
18
Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription.
Sandie Tuduri, Laure Crabbé, Chiara Conti, Hélène Tourrière, Heidi Holtgreve-Grez, Anna Jauch, Véronique Pantesco, John De Vos, Aubin Thomas, Charles Theillet,[...]. Nat Cell Biol 2009
Sandie Tuduri, Laure Crabbé, Chiara Conti, Hélène Tourrière, Heidi Holtgreve-Grez, Anna Jauch, Véronique Pantesco, John De Vos, Aubin Thomas, Charles Theillet,[...]. Nat Cell Biol 2009
18
Co-transcriptional R-loops are the main cause of estrogen-induced DNA damage.
Caroline Townsend Stork, Michael Bocek, Madzia P Crossley, Julie Sollier, Lionel A Sanz, Frédéric Chédin, Tomek Swigut, Karlene A Cimprich. Elife 2016
Caroline Townsend Stork, Michael Bocek, Madzia P Crossley, Julie Sollier, Lionel A Sanz, Frédéric Chédin, Tomek Swigut, Karlene A Cimprich. Elife 2016
18
Aicardi-Goutières syndrome and the type I interferonopathies.
Yanick J Crow, Nicolas Manel. Nat Rev Immunol 2015
Yanick J Crow, Nicolas Manel. Nat Rev Immunol 2015
18
Trex1 prevents cell-intrinsic initiation of autoimmunity.
Daniel B Stetson, Joan S Ko, Thierry Heidmann, Ruslan Medzhitov. Cell 2008
Daniel B Stetson, Joan S Ko, Thierry Heidmann, Ruslan Medzhitov. Cell 2008
17
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships.
Julie Nadel, Rodoniki Athanasiadou, Christophe Lemetre, N Ari Wijetunga, Pilib Ó Broin, Hanae Sato, Zhengdong Zhang, Jeffrey Jeddeloh, Cristina Montagna, Aaron Golden,[...]. Epigenetics Chromatin 2015
Julie Nadel, Rodoniki Athanasiadou, Christophe Lemetre, N Ari Wijetunga, Pilib Ó Broin, Hanae Sato, Zhengdong Zhang, Jeffrey Jeddeloh, Cristina Montagna, Aaron Golden,[...]. Epigenetics Chromatin 2015
21
Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability.
Xialu Li, James L Manley. Cell 2005
Xialu Li, James L Manley. Cell 2005
17
Yeast Sen1 helicase protects the genome from transcription-associated instability.
Hannah E Mischo, Belén Gómez-González, Pawel Grzechnik, Ana G Rondón, Wu Wei, Lars Steinmetz, Andrés Aguilera, Nick J Proudfoot. Mol Cell 2011
Hannah E Mischo, Belén Gómez-González, Pawel Grzechnik, Ana G Rondón, Wu Wei, Lars Steinmetz, Andrés Aguilera, Nick J Proudfoot. Mol Cell 2011
16
R-loops associated with triplet repeat expansions promote gene silencing in Friedreich ataxia and fragile X syndrome.
Matthias Groh, Michele M P Lufino, Richard Wade-Martins, Natalia Gromak. PLoS Genet 2014
Matthias Groh, Michele M P Lufino, Richard Wade-Martins, Natalia Gromak. PLoS Genet 2014
16
Characterization of human disease phenotypes associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR, and IFIH1.
Yanick J Crow, Diana S Chase, Johanna Lowenstein Schmidt, Marcin Szynkiewicz, Gabriella M A Forte, Hannah L Gornall, Anthony Oojageer, Beverley Anderson, Amy Pizzino, Guy Helman,[...]. Am J Med Genet A 2015
Yanick J Crow, Diana S Chase, Johanna Lowenstein Schmidt, Marcin Szynkiewicz, Gabriella M A Forte, Hannah L Gornall, Anthony Oojageer, Beverley Anderson, Amy Pizzino, Guy Helman,[...]. Am J Med Genet A 2015
16
Arginine methylation facilitates the recruitment of TOP3B to chromatin to prevent R loop accumulation.
Yanzhong Yang, Kevin M McBride, Sean Hensley, Yue Lu, Frederic Chedin, Mark T Bedford. Mol Cell 2014
Yanzhong Yang, Kevin M McBride, Sean Hensley, Yue Lu, Frederic Chedin, Mark T Bedford. Mol Cell 2014
16
Characterization of monoclonal antibody to DNA.RNA and its application to immunodetection of hybrids.
S J Boguslawski, D E Smith, M A Michalak, K E Mickelson, C O Yehle, W L Patterson, R J Carrico. J Immunol Methods 1986
S J Boguslawski, D E Smith, M A Michalak, K E Mickelson, C O Yehle, W L Patterson, R J Carrico. J Immunol Methods 1986
16
R-Loops as Cellular Regulators and Genomic Threats.
Madzia P Crossley, Michael Bocek, Karlene A Cimprich. Mol Cell 2019
Madzia P Crossley, Michael Bocek, Karlene A Cimprich. Mol Cell 2019
16
Mammalian RNase H2 removes ribonucleotides from DNA to maintain genome integrity.
Bjoern Hiller, Martin Achleitner, Silke Glage, Ronald Naumann, Rayk Behrendt, Axel Roers. J Exp Med 2012
Bjoern Hiller, Martin Achleitner, Silke Glage, Ronald Naumann, Rayk Behrendt, Axel Roers. J Exp Med 2012
15
RNase H2-initiated ribonucleotide excision repair.
Justin L Sparks, Hyongi Chon, Susana M Cerritelli, Thomas A Kunkel, Erik Johansson, Robert J Crouch, Peter M Burgers. Mol Cell 2012
Justin L Sparks, Hyongi Chon, Susana M Cerritelli, Thomas A Kunkel, Erik Johansson, Robert J Crouch, Peter M Burgers. Mol Cell 2012
15
Abundant ribonucleotide incorporation into DNA by yeast replicative polymerases.
Stephanie A Nick McElhinny, Brian E Watts, Dinesh Kumar, Danielle L Watt, Else-Britt Lundström, Peter M J Burgers, Erik Johansson, Andrei Chabes, Thomas A Kunkel. Proc Natl Acad Sci U S A 2010
Stephanie A Nick McElhinny, Brian E Watts, Dinesh Kumar, Danielle L Watt, Else-Britt Lundström, Peter M J Burgers, Erik Johansson, Andrei Chabes, Thomas A Kunkel. Proc Natl Acad Sci U S A 2010
14
Transcription-associated R-loop formation across the human FMR1 CGG-repeat region.
Erick W Loomis, Lionel A Sanz, Frédéric Chédin, Paul J Hagerman. PLoS Genet 2014
Erick W Loomis, Lionel A Sanz, Frédéric Chédin, Paul J Hagerman. PLoS Genet 2014
14
RNase H2 roles in genome integrity revealed by unlinking its activities.
Hyongi Chon, Justin L Sparks, Monika Rychlik, Marcin Nowotny, Peter M Burgers, Robert J Crouch, Susana M Cerritelli. Nucleic Acids Res 2013
Hyongi Chon, Justin L Sparks, Monika Rychlik, Marcin Nowotny, Peter M Burgers, Robert J Crouch, Susana M Cerritelli. Nucleic Acids Res 2013
14
Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature.
Gillian I Rice, Paul R Kasher, Gabriella M A Forte, Niamh M Mannion, Sam M Greenwood, Marcin Szynkiewicz, Jonathan E Dickerson, Sanjeev S Bhaskar, Massimiliano Zampini, Tracy A Briggs,[...]. Nat Genet 2012
Gillian I Rice, Paul R Kasher, Gabriella M A Forte, Niamh M Mannion, Sam M Greenwood, Marcin Szynkiewicz, Jonathan E Dickerson, Sanjeev S Bhaskar, Massimiliano Zampini, Tracy A Briggs,[...]. Nat Genet 2012
14
RNase H2 catalytic core Aicardi-Goutières syndrome-related mutant invokes cGAS-STING innate immune-sensing pathway in mice.
Vladislav Pokatayev, Naushaba Hasin, Hyongi Chon, Susana M Cerritelli, Kiran Sakhuja, Jerrold M Ward, H Douglas Morris, Nan Yan, Robert J Crouch. J Exp Med 2016
Vladislav Pokatayev, Naushaba Hasin, Hyongi Chon, Susana M Cerritelli, Kiran Sakhuja, Jerrold M Ward, H Douglas Morris, Nan Yan, Robert J Crouch. J Exp Med 2016
14
Genome instability due to ribonucleotide incorporation into DNA.
Stephanie A Nick McElhinny, Dinesh Kumar, Alan B Clark, Danielle L Watt, Brian E Watts, Else-Britt Lundström, Erik Johansson, Andrei Chabes, Thomas A Kunkel. Nat Chem Biol 2010
Stephanie A Nick McElhinny, Dinesh Kumar, Alan B Clark, Danielle L Watt, Brian E Watts, Else-Britt Lundström, Erik Johansson, Andrei Chabes, Thomas A Kunkel. Nat Chem Biol 2010
13
R-loop formation at Snord116 mediates topotecan inhibition of Ube3a-antisense and allele-specific chromatin decondensation.
Weston T Powell, Rochelle L Coulson, Michael L Gonzales, Florence K Crary, Spencer S Wong, Sarrita Adams, Robert A Ach, Peter Tsang, Nazumi Alice Yamada, Dag H Yasui,[...]. Proc Natl Acad Sci U S A 2013
Weston T Powell, Rochelle L Coulson, Michael L Gonzales, Florence K Crary, Spencer S Wong, Sarrita Adams, Robert A Ach, Peter Tsang, Nazumi Alice Yamada, Dag H Yasui,[...]. Proc Natl Acad Sci U S A 2013
13
Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease.
Yun-Gui Yang, Tomas Lindahl, Deborah E Barnes. Cell 2007
Yun-Gui Yang, Tomas Lindahl, Deborah E Barnes. Cell 2007
13
R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants.
Peter C Stirling, Yujia A Chan, Sean W Minaker, Maria J Aristizabal, Irene Barrett, Payal Sipahimalani, Michael S Kobor, Philip Hieter. Genes Dev 2012
Peter C Stirling, Yujia A Chan, Sean W Minaker, Maria J Aristizabal, Irene Barrett, Payal Sipahimalani, Michael S Kobor, Philip Hieter. Genes Dev 2012
13
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.