A citation-based method for searching scientific literature

E John Wherry, Makoto Kurachi. Nat Rev Immunol 2015
Times Cited: 1644







List of co-cited articles
760 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


T cell exhaustion.
E John Wherry. Nat Immunol 2011
22

CD8 T Cell Exhaustion During Chronic Viral Infection and Cancer.
Laura M McLane, Mohamed S Abdel-Hakeem, E John Wherry. Annu Rev Immunol 2019
404
15

Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection.
Michael A Paley, Daniela C Kroy, Pamela M Odorizzi, Jonathan B Johnnidis, Douglas V Dolfi, Burton E Barnett, Elizabeth K Bikoff, Elizabeth J Robertson, Georg M Lauer, Steven L Reiner,[...]. Science 2012
489
13

Molecular signature of CD8+ T cell exhaustion during chronic viral infection.
E John Wherry, Sang-Jun Ha, Susan M Kaech, W Nicholas Haining, Surojit Sarkar, Vandana Kalia, Shruti Subramaniam, Joseph N Blattman, Daniel L Barber, Rafi Ahmed. Immunity 2007
13

TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion.
Omar Khan, Josephine R Giles, Sierra McDonald, Sasikanth Manne, Shin Foong Ngiow, Kunal P Patel, Michael T Werner, Alexander C Huang, Katherine A Alexander, Jennifer E Wu,[...]. Nature 2019
323
13

Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade.
Brian C Miller, Debattama R Sen, Rose Al Abosy, Kevin Bi, Yamini V Virkud, Martin W LaFleur, Kathleen B Yates, Ana Lako, Kristen Felt, Girish S Naik,[...]. Nat Immunol 2019
384
12

Intratumoral Tcf1+PD-1+CD8+ T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy.
Imran Siddiqui, Karin Schaeuble, Vijaykumar Chennupati, Silvia A Fuertes Marraco, Sandra Calderon-Copete, Daniela Pais Ferreira, Santiago J Carmona, Leonardo Scarpellino, David Gfeller, Sylvain Pradervand,[...]. Immunity 2019
334
12

TOX is a critical regulator of tumour-specific T cell differentiation.
Andrew C Scott, Friederike Dündar, Paul Zumbo, Smita S Chandran, Christopher A Klebanoff, Mojdeh Shakiba, Prerak Trivedi, Laura Menocal, Heather Appleby, Steven Camara,[...]. Nature 2019
261
12

Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy.
Se Jin Im, Masao Hashimoto, Michael Y Gerner, Junghwa Lee, Haydn T Kissick, Matheus C Burger, Qiang Shan, J Scott Hale, Judong Lee, Tahseen H Nasti,[...]. Nature 2016
675
12

T Cell Factor 1-Expressing Memory-like CD8(+) T Cells Sustain the Immune Response to Chronic Viral Infections.
Daniel T Utzschneider, Mélanie Charmoy, Vijaykumar Chennupati, Laurène Pousse, Daniela Pais Ferreira, Sandra Calderon-Copete, Maxime Danilo, Francesca Alfei, Maike Hofmann, Dominik Wieland,[...]. Immunity 2016
333
11

Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade.
Kristen E Pauken, Morgan A Sammons, Pamela M Odorizzi, Sasikanth Manne, Jernej Godec, Omar Khan, Adam M Drake, Zeyu Chen, Debattama R Sen, Makoto Kurachi,[...]. Science 2016
521
10

The TCF1-Bcl6 axis counteracts type I interferon to repress exhaustion and maintain T cell stemness.
Tuoqi Wu, Yun Ji, E Ashley Moseman, Haifeng C Xu, Monica Manglani, Martha Kirby, Stacie M Anderson, Robin Handon, Elizabeth Kenyon, Abdel Elkahloun,[...]. Sci Immunol 2016
193
10

Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection.
Chen Yao, Hong-Wei Sun, Neal E Lacey, Yun Ji, E Ashley Moseman, Han-Yu Shih, Elisabeth F Heuston, Martha Kirby, Stacie Anderson, Jun Cheng,[...]. Nat Immunol 2019
160
9

NR4A transcription factors limit CAR T cell function in solid tumours.
Joyce Chen, Isaac F López-Moyado, Hyungseok Seo, Chan-Wang J Lio, Laura J Hempleman, Takashi Sekiya, Akihiko Yoshimura, James P Scott-Browne, Anjana Rao. Nature 2019
202
9

Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection.
Shawn D Blackburn, Haina Shin, W Nicholas Haining, Tao Zou, Creg J Workman, Antonio Polley, Michael R Betts, Gordon J Freeman, Dario A A Vignali, E John Wherry. Nat Immunol 2009
9

Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor.
Nikhil S Joshi, Weiguo Cui, Anmol Chandele, Heung Kyu Lee, David R Urso, James Hagman, Laurent Gapin, Susan M Kaech. Immunity 2007
9

TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision.
Zeyu Chen, Zhicheng Ji, Shin Foong Ngiow, Sasikanth Manne, Zhangying Cai, Alexander C Huang, John Johnson, Ryan P Staupe, Bertram Bengsch, Caiyue Xu,[...]. Immunity 2019
146
8

Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms.
Jean-Christophe Beltra, Sasikanth Manne, Mohamed S Abdel-Hakeem, Makoto Kurachi, Josephine R Giles, Zeyu Chen, Valentina Casella, Shin Foong Ngiow, Omar Khan, Yinghui Jane Huang,[...]. Immunity 2020
105
8

The epigenetic landscape of T cell exhaustion.
Debattama R Sen, James Kaminski, R Anthony Barnitz, Makoto Kurachi, Ulrike Gerdemann, Kathleen B Yates, Hsiao-Wei Tsao, Jernej Godec, Martin W LaFleur, Flavian D Brown,[...]. Science 2016
406
8

TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection.
Francesca Alfei, Kristiyan Kanev, Maike Hofmann, Ming Wu, Hazem E Ghoneim, Patrick Roelli, Daniel T Utzschneider, Madlaina von Hoesslin, Jolie G Cullen, Yiping Fan,[...]. Nature 2019
231
8

Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy.
Padmanee Sharma, Siwen Hu-Lieskovan, Jennifer A Wargo, Antoni Ribas. Cell 2017
8

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions.
F Sallusto, D Lenig, R Förster, M Lipp, A Lanzavecchia. Nature 1999
8

Cancer immunotherapy using checkpoint blockade.
Antoni Ribas, Jedd D Wolchok. Science 2018
7

Tumor-Specific T Cell Dysfunction Is a Dynamic Antigen-Driven Differentiation Program Initiated Early during Tumorigenesis.
Andrea Schietinger, Mary Philip, Varintra E Krisnawan, Edison Y Chiu, Jeffrey J Delrow, Ryan S Basom, Peter Lauer, Dirk G Brockstedt, Sue E Knoblaugh, Günter J Hämmerling,[...]. Immunity 2016
261
7

TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8+ T cell exhaustion.
Hyungseok Seo, Joyce Chen, Edahí González-Avalos, Daniela Samaniego-Castruita, Arundhoti Das, Yueqiang H Wang, Isaac F López-Moyado, Romain O Georges, Wade Zhang, Atsushi Onodera,[...]. Proc Natl Acad Sci U S A 2019
183
7

Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma.
Sattva S Neelapu, Frederick L Locke, Nancy L Bartlett, Lazaros J Lekakis, David B Miklos, Caron A Jacobson, Ira Braunschweig, Olalekan O Oluwole, Tanya Siddiqi, Yi Lin,[...]. N Engl J Med 2017
7

Overcoming T cell exhaustion in infection and cancer.
Kristen E Pauken, E John Wherry. Trends Immunol 2015
523
7

PD-1 blockade induces responses by inhibiting adaptive immune resistance.
Paul C Tumeh, Christina L Harview, Jennifer H Yearley, I Peter Shintaku, Emma J M Taylor, Lidia Robert, Bartosz Chmielowski, Marko Spasic, Gina Henry, Voicu Ciobanu,[...]. Nature 2014
7

Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma.
Robert J Motzer, Nizar M Tannir, David F McDermott, Osvaldo Arén Frontera, Bohuslav Melichar, Toni K Choueiri, Elizabeth R Plimack, Philippe Barthélémy, Camillo Porta, Saby George,[...]. N Engl J Med 2018
7

Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer.
Naiyer A Rizvi, Matthew D Hellmann, Alexandra Snyder, Pia Kvistborg, Vladimir Makarov, Jonathan J Havel, William Lee, Jianda Yuan, Phillip Wong, Teresa S Ho,[...]. Science 2015
7

Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic Infection.
William H Hudson, Julia Gensheimer, Masao Hashimoto, Andreas Wieland, Rajesh M Valanparambil, Peng Li, Jian-Xin Lin, Bogumila T Konieczny, Se Jin Im, Gordon J Freeman,[...]. Immunity 2019
107
7

Restoring function in exhausted CD8 T cells during chronic viral infection.
Daniel L Barber, E John Wherry, David Masopust, Baogong Zhu, James P Allison, Arlene H Sharpe, Gordon J Freeman, Rafi Ahmed. Nature 2006
7

The transcription factor NFAT promotes exhaustion of activated CD8⁺ T cells.
Gustavo J Martinez, Renata M Pereira, Tarmo Äijö, Edward Y Kim, Francesco Marangoni, Matthew E Pipkin, Susan Togher, Vigo Heissmeyer, Yi Chen Zhang, Shane Crotty,[...]. Immunity 2015
289
6

Improved survival with ipilimumab in patients with metastatic melanoma.
F Stephen Hodi, Steven J O'Day, David F McDermott, Robert W Weber, Jeffrey A Sosman, John B Haanen, Rene Gonzalez, Caroline Robert, Dirk Schadendorf, Jessica C Hassel,[...]. N Engl J Med 2010
6

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression.
Chih-Hao Chang, Jing Qiu, David O'Sullivan, Michael D Buck, Takuro Noguchi, Jonathan D Curtis, Qiongyu Chen, Mariel Gindin, Matthew M Gubin, Gerritje J W van der Windt,[...]. Cell 2015
6

Network analysis reveals centrally connected genes and pathways involved in CD8+ T cell exhaustion versus memory.
Travis A Doering, Alison Crawford, Jill M Angelosanto, Michael A Paley, Carly G Ziegler, E John Wherry. Immunity 2012
295
6

Cancer statistics, 2020.
Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal. CA Cancer J Clin 2020
6

Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints.
Shohei Koyama, Esra A Akbay, Yvonne Y Li, Grit S Herter-Sprie, Kevin A Buczkowski, William G Richards, Leena Gandhi, Amanda J Redig, Scott J Rodig, Hajime Asahina,[...]. Nat Commun 2016
729
6

De Novo Epigenetic Programs Inhibit PD-1 Blockade-Mediated T Cell Rejuvenation.
Hazem E Ghoneim, Yiping Fan, Ardiana Moustaki, Hossam A Abdelsamed, Pradyot Dash, Pranay Dogra, Robert Carter, Walid Awad, Geoff Neale, Paul G Thomas,[...]. Cell 2017
292
6

Defining 'T cell exhaustion'.
Christian U Blank, W Nicholas Haining, Werner Held, Patrick G Hogan, Axel Kallies, Enrico Lugli, Rachel C Lynn, Mary Philip, Anjana Rao, Nicholas P Restifo,[...]. Nat Rev Immunol 2019
243
6


Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1-CD8+ Tumor-Infiltrating T Cells.
Sema Kurtulus, Asaf Madi, Giulia Escobar, Max Klapholz, Jackson Nyman, Elena Christian, Mathias Pawlak, Danielle Dionne, Junrong Xia, Orit Rozenblatt-Rosen,[...]. Immunity 2019
199
6

Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment.
E John Wherry, Joseph N Blattman, Kaja Murali-Krishna, Robbert van der Most, Rafi Ahmed. J Virol 2003
6

Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin.
Andrew M Intlekofer, Naofumi Takemoto, E John Wherry, Sarah A Longworth, John T Northrup, Vikram R Palanivel, Alan C Mullen, Christopher R Gasink, Susan M Kaech, Joseph D Miller,[...]. Nat Immunol 2005
828
6

T-cell invigoration to tumour burden ratio associated with anti-PD-1 response.
Alexander C Huang, Michael A Postow, Robert J Orlowski, Rosemarie Mick, Bertram Bengsch, Sasikanth Manne, Wei Xu, Shannon Harmon, Josephine R Giles, Brandon Wenz,[...]. Nature 2017
707
6

CD4+ T Cell Help Is Required for the Formation of a Cytolytic CD8+ T Cell Subset that Protects against Chronic Infection and Cancer.
Ryan Zander, David Schauder, Gang Xin, Christine Nguyen, Xiaopeng Wu, Allan Zajac, Weiguo Cui. Immunity 2019
113
6

Landscape of Infiltrating T Cells in Liver Cancer Revealed by Single-Cell Sequencing.
Chunhong Zheng, Liangtao Zheng, Jae-Kwang Yoo, Huahu Guo, Yuanyuan Zhang, Xinyi Guo, Boxi Kang, Ruozhen Hu, Julie Y Huang, Qiming Zhang,[...]. Cell 2017
680
6

Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma.
Jesse M Zaretsky, Angel Garcia-Diaz, Daniel S Shin, Helena Escuin-Ordinas, Willy Hugo, Siwen Hu-Lieskovan, Davis Y Torrejon, Gabriel Abril-Rodriguez, Salemiz Sandoval, Lucas Barthly,[...]. N Engl J Med 2016
5

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2.
Michael I Love, Wolfgang Huber, Simon Anders. Genome Biol 2014
5

Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma.
Moshe Sade-Feldman, Keren Yizhak, Stacey L Bjorgaard, John P Ray, Carl G de Boer, Russell W Jenkins, David J Lieb, Jonathan H Chen, Dennie T Frederick, Michal Barzily-Rokni,[...]. Cell 2018
469
5


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.