David M Ornitz, Pierre J Marie. Genes Dev 2015
Times Cited: 216
Times Cited: 216
Times Cited
Times Co-cited
Similarity
The Fibroblast Growth Factor signaling pathway.
David M Ornitz, Nobuyuki Itoh. Wiley Interdiscip Rev Dev Biol 2015
David M Ornitz, Nobuyuki Itoh. Wiley Interdiscip Rev Dev Biol 2015
27
The FGF family: biology, pathophysiology and therapy.
Andrew Beenken, Moosa Mohammadi. Nat Rev Drug Discov 2009
Andrew Beenken, Moosa Mohammadi. Nat Rev Drug Discov 2009
13
Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease.
Nobuyuki Itoh, David M Ornitz. J Biochem 2011
Nobuyuki Itoh, David M Ornitz. J Biochem 2011
11
Role of FGF/FGFR signaling in skeletal development and homeostasis: learning from mouse models.
Nan Su, Min Jin, Lin Chen. Bone Res 2014
Nan Su, Min Jin, Lin Chen. Bone Res 2014
11
Fibroblast growth factor signalling: from development to cancer.
Nicholas Turner, Richard Grose. Nat Rev Cancer 2010
Nicholas Turner, Richard Grose. Nat Rev Cancer 2010
10
Disruption of the fibroblast growth factor-2 gene results in decreased bone mass and bone formation.
A Montero, Y Okada, M Tomita, M Ito, H Tsurukami, T Nakamura, T Doetschman, J D Coffin, M M Hurley. J Clin Invest 2000
A Montero, Y Okada, M Tomita, M Ito, H Tsurukami, T Nakamura, T Doetschman, J D Coffin, M M Hurley. J Clin Invest 2000
9
Exploring mechanisms of FGF signalling through the lens of structural biology.
Regina Goetz, Moosa Mohammadi. Nat Rev Mol Cell Biol 2013
Regina Goetz, Moosa Mohammadi. Nat Rev Mol Cell Biol 2013
9
Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts.
T Komori, H Yagi, S Nomura, A Yamaguchi, K Sasaki, K Deguchi, Y Shimizu, R T Bronson, Y H Gao, M Inada,[...]. Cell 1997
T Komori, H Yagi, S Nomura, A Yamaguchi, K Sasaki, K Deguchi, Y Shimizu, R T Bronson, Y H Gao, M Inada,[...]. Cell 1997
8
Fibroblast growth factors in skeletal development.
David M Ornitz, Pierre J Marie. Curr Top Dev Biol 2019
David M Ornitz, Pierre J Marie. Curr Top Dev Biol 2019
36
FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis.
Norihiko Ohbayashi, Masaki Shibayama, Yoko Kurotaki, Mayumi Imanishi, Toshihiko Fujimori, Nobuyuki Itoh, Shinji Takada. Genes Dev 2002
Norihiko Ohbayashi, Masaki Shibayama, Yoko Kurotaki, Mayumi Imanishi, Toshihiko Fujimori, Nobuyuki Itoh, Shinji Takada. Genes Dev 2002
7
FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease.
David M Ornitz, Pierre J Marie. Genes Dev 2002
David M Ornitz, Pierre J Marie. Genes Dev 2002
7
Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia.
R Shiang, L M Thompson, Y Z Zhu, D M Church, T J Fielder, M Bocian, S T Winokur, J J Wasmuth. Cell 1994
R Shiang, L M Thompson, Y Z Zhu, D M Church, T J Fielder, M Bocian, S T Winokur, J J Wasmuth. Cell 1994
7
The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6.
Haruhiko Akiyama, Marie-Christine Chaboissier, James F Martin, Andreas Schedl, Benoit de Crombrugghe. Genes Dev 2002
Haruhiko Akiyama, Marie-Christine Chaboissier, James F Martin, Andreas Schedl, Benoit de Crombrugghe. Genes Dev 2002
7
Fibroblast growth factor receptor 1 signaling in the osteo-chondrogenic cell lineage regulates sequential steps of osteoblast maturation.
Anne L Jacob, Craig Smith, Juha Partanen, David M Ornitz. Dev Biol 2006
Anne L Jacob, Craig Smith, Juha Partanen, David M Ornitz. Dev Biol 2006
7
A combined series of Fgf9 and Fgf18 mutant alleles identifies unique and redundant roles in skeletal development.
Irene H Hung, Gary C Schoenwolf, Mark Lewandoski, David M Ornitz. Dev Biol 2016
Irene H Hung, Gary C Schoenwolf, Mark Lewandoski, David M Ornitz. Dev Biol 2016
20
FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod.
Irene H Hung, Kai Yu, Kory J Lavine, David M Ornitz. Dev Biol 2007
Irene H Hung, Kai Yu, Kory J Lavine, David M Ornitz. Dev Biol 2007
7
TGF-β and BMP signaling in osteoblast, skeletal development, and bone formation, homeostasis and disease.
Mengrui Wu, Guiqian Chen, Yi-Ping Li. Bone Res 2016
Mengrui Wu, Guiqian Chen, Yi-Ping Li. Bone Res 2016
7
Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway.
Hiroshi Hanafusa, Satoru Torii, Takayuki Yasunaga, Eisuke Nishida. Nat Cell Biol 2002
Hiroshi Hanafusa, Satoru Torii, Takayuki Yasunaga, Eisuke Nishida. Nat Cell Biol 2002
6
Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes.
Dongyao Yan, Di Chen, Simon M Cool, Andre J van Wijnen, Katalin Mikecz, Gillian Murphy, Hee-Jeong Im. Arthritis Res Ther 2011
Dongyao Yan, Di Chen, Simon M Cool, Andre J van Wijnen, Katalin Mikecz, Gillian Murphy, Hee-Jeong Im. Arthritis Res Ther 2011
6
Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis.
Timothy F Day, Xizhi Guo, Lisa Garrett-Beal, Yingzi Yang. Dev Cell 2005
Timothy F Day, Xizhi Guo, Lisa Garrett-Beal, Yingzi Yang. Dev Cell 2005
6
The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation.
Kazuhisa Nakashima, Xin Zhou, Gary Kunkel, Zhaoping Zhang, Jian Min Deng, Richard R Behringer, Benoit de Crombrugghe. Cell 2002
Kazuhisa Nakashima, Xin Zhou, Gary Kunkel, Zhaoping Zhang, Jian Min Deng, Richard R Behringer, Benoit de Crombrugghe. Cell 2002
6
Role of fibroblast growth factors in bone regeneration.
Pornkawee Charoenlarp, Arun Kumar Rajendran, Sachiko Iseki. Inflamm Regen 2017
Pornkawee Charoenlarp, Arun Kumar Rajendran, Sachiko Iseki. Inflamm Regen 2017
17
Resting zone of the growth plate houses a unique class of skeletal stem cells.
Koji Mizuhashi, Wanida Ono, Yuki Matsushita, Naoko Sakagami, Akira Takahashi, Thomas L Saunders, Takashi Nagasawa, Henry M Kronenberg, Noriaki Ono. Nature 2018
Koji Mizuhashi, Wanida Ono, Yuki Matsushita, Naoko Sakagami, Akira Takahashi, Thomas L Saunders, Takashi Nagasawa, Henry M Kronenberg, Noriaki Ono. Nature 2018
6
Discovery of a periosteal stem cell mediating intramembranous bone formation.
Shawon Debnath, Alisha R Yallowitz, Jason McCormick, Sarfaraz Lalani, Tuo Zhang, Ren Xu, Na Li, Yifang Liu, Yeon Suk Yang, Mark Eiseman,[...]. Nature 2018
Shawon Debnath, Alisha R Yallowitz, Jason McCormick, Sarfaraz Lalani, Tuo Zhang, Ren Xu, Na Li, Yifang Liu, Yeon Suk Yang, Mark Eiseman,[...]. Nature 2018
6
FGF signaling in the developing endochondral skeleton.
David M Ornitz. Cytokine Growth Factor Rev 2005
David M Ornitz. Cytokine Growth Factor Rev 2005
6
BMP signalling in skeletal development, disease and repair.
Valerie S Salazar, Laura W Gamer, Vicki Rosen. Nat Rev Endocrinol 2016
Valerie S Salazar, Laura W Gamer, Vicki Rosen. Nat Rev Endocrinol 2016
6
Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation.
B St-Jacques, M Hammerschmidt, A P McMahon. Genes Dev 1999
B St-Jacques, M Hammerschmidt, A P McMahon. Genes Dev 1999
6
Fibroblast growth factor (FGF) signaling in development and skeletal diseases.
Chad M Teven, Evan M Farina, Jane Rivas, Russell R Reid. Genes Dis 2014
Chad M Teven, Evan M Farina, Jane Rivas, Russell R Reid. Genes Dis 2014
5
Genetic inhibition of fibroblast growth factor receptor 1 in knee cartilage attenuates the degeneration of articular cartilage in adult mice.
Tujun Weng, Lingxian Yi, Junlan Huang, Fengtao Luo, Xuan Wen, Xiaolan Du, Qian Chen, Chuxia Deng, Di Chen, Lin Chen. Arthritis Rheum 2012
Tujun Weng, Lingxian Yi, Junlan Huang, Fengtao Luo, Xuan Wen, Xiaolan Du, Qian Chen, Chuxia Deng, Di Chen, Lin Chen. Arthritis Rheum 2012
8
VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation.
H P Gerber, T H Vu, A M Ryan, J Kowalski, Z Werb, N Ferrara. Nat Med 1999
H P Gerber, T H Vu, A M Ryan, J Kowalski, Z Werb, N Ferrara. Nat Med 1999
5
Hypertrophic chondrocytes can become osteoblasts and osteocytes in endochondral bone formation.
Liu Yang, Kwok Yeung Tsang, Hoi Ching Tang, Danny Chan, Kathryn S E Cheah. Proc Natl Acad Sci U S A 2014
Liu Yang, Kwok Yeung Tsang, Hoi Ching Tang, Danny Chan, Kathryn S E Cheah. Proc Natl Acad Sci U S A 2014
5
Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization.
J Schlessinger, A N Plotnikov, O A Ibrahimi, A V Eliseenkova, B K Yeh, A Yayon, R J Linhardt, M Mohammadi. Mol Cell 2000
J Schlessinger, A N Plotnikov, O A Ibrahimi, A V Eliseenkova, B K Yeh, A Yayon, R J Linhardt, M Mohammadi. Mol Cell 2000
5
Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3.
J S Colvin, B A Bohne, G W Harding, D G McEwen, D M Ornitz. Nat Genet 1996
J S Colvin, B A Bohne, G W Harding, D G McEwen, D M Ornitz. Nat Genet 1996
5
Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity.
A N Plotnikov, S R Hubbard, J Schlessinger, M Mohammadi. Cell 2000
A N Plotnikov, S R Hubbard, J Schlessinger, M Mohammadi. Cell 2000
5
Molecular mechanisms of fibroblast growth factor signaling in physiology and pathology.
Artur A Belov, Moosa Mohammadi. Cold Spring Harb Perspect Biol 2013
Artur A Belov, Moosa Mohammadi. Cold Spring Harb Perspect Biol 2013
5
Mechanism of FGF receptor dimerization and activation.
Sarvenaz Sarabipour, Kalina Hristova. Nat Commun 2016
Sarvenaz Sarabipour, Kalina Hristova. Nat Commun 2016
5
Constitutively-active FGFR3 disrupts primary cilium length and IFT20 trafficking in various chondrocyte models of achondroplasia.
Ludovic Martin, Nabil Kaci, Valentin Estibals, Nicolas Goudin, Meriem Garfa-Traore, Catherine Benoist-Lasselin, Emilie Dambroise, Laurence Legeai-Mallet. Hum Mol Genet 2018
Ludovic Martin, Nabil Kaci, Valentin Estibals, Nicolas Goudin, Meriem Garfa-Traore, Catherine Benoist-Lasselin, Emilie Dambroise, Laurence Legeai-Mallet. Hum Mol Genet 2018
20
Fibroblast growth factor receptor signaling in kidney and lower urinary tract development.
Kenneth A Walker, Sunder Sims-Lucas, Carlton M Bates. Pediatr Nephrol 2016
Kenneth A Walker, Sunder Sims-Lucas, Carlton M Bates. Pediatr Nephrol 2016
11
A subset of chondrogenic cells provides early mesenchymal progenitors in growing bones.
Noriaki Ono, Wanida Ono, Takashi Nagasawa, Henry M Kronenberg. Nat Cell Biol 2014
Noriaki Ono, Wanida Ono, Takashi Nagasawa, Henry M Kronenberg. Nat Cell Biol 2014
5
Genetic insights into the mechanisms of Fgf signaling.
J Richard Brewer, Pierre Mazot, Philippe Soriano. Genes Dev 2016
J Richard Brewer, Pierre Mazot, Philippe Soriano. Genes Dev 2016
5
Osteo-chondroprogenitor cells are derived from Sox9 expressing precursors.
Haruhiko Akiyama, Jung-Eun Kim, Kazuhisa Nakashima, Gener Balmes, Naomi Iwai, Jian Min Deng, Zhaoping Zhang, James F Martin, Richard R Behringer, Takashi Nakamura,[...]. Proc Natl Acad Sci U S A 2005
Haruhiko Akiyama, Jung-Eun Kim, Kazuhisa Nakashima, Gener Balmes, Naomi Iwai, Jian Min Deng, Zhaoping Zhang, James F Martin, Richard R Behringer, Takashi Nakamura,[...]. Proc Natl Acad Sci U S A 2005
5
Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family.
Xiuqin Zhang, Omar A Ibrahimi, Shaun K Olsen, Hisashi Umemori, Moosa Mohammadi, David M Ornitz. J Biol Chem 2006
Xiuqin Zhang, Omar A Ibrahimi, Shaun K Olsen, Hisashi Umemori, Moosa Mohammadi, David M Ornitz. J Biol Chem 2006
5
TGF-β and BMP signaling in osteoblast differentiation and bone formation.
Guiqian Chen, Chuxia Deng, Yi-Ping Li. Int J Biol Sci 2012
Guiqian Chen, Chuxia Deng, Yi-Ping Li. Int J Biol Sci 2012
5
A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate.
Phillip T Newton, Lei Li, Baoyi Zhou, Christoph Schweingruber, Maria Hovorakova, Meng Xie, Xiaoyan Sun, Lakshmi Sandhow, Artem V Artemov, Evgeny Ivashkin,[...]. Nature 2019
Phillip T Newton, Lei Li, Baoyi Zhou, Christoph Schweingruber, Maria Hovorakova, Meng Xie, Xiaoyan Sun, Lakshmi Sandhow, Artem V Artemov, Evgeny Ivashkin,[...]. Nature 2019
7
Osteoblast precursors, but not mature osteoblasts, move into developing and fractured bones along with invading blood vessels.
Christa Maes, Tatsuya Kobayashi, Martin K Selig, Sophie Torrekens, Sanford I Roth, Susan Mackem, Geert Carmeliet, Henry M Kronenberg. Dev Cell 2010
Christa Maes, Tatsuya Kobayashi, Martin K Selig, Sophie Torrekens, Sanford I Roth, Susan Mackem, Geert Carmeliet, Henry M Kronenberg. Dev Cell 2010
5
Fgfr1 and Fgfr2 have distinct differentiation- and proliferation-related roles in the developing mouse skull vault.
S Iseki, A O Wilkie, G M Morriss-Kay. Development 1999
S Iseki, A O Wilkie, G M Morriss-Kay. Development 1999
5
Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18.
Zhonghao Liu, Jingsong Xu, Jennifer S Colvin, David M Ornitz. Genes Dev 2002
Zhonghao Liu, Jingsong Xu, Jennifer S Colvin, David M Ornitz. Genes Dev 2002
5
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.