A citation-based method for searching scientific literature

Lucas B Sullivan, Dan Y Gui, Aaron M Hosios, Lauren N Bush, Elizaveta Freinkman, Matthew G Vander Heiden. Cell 2015
Times Cited: 588







List of co-cited articles
813 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis.
Kıvanç Birsoy, Tim Wang, Walter W Chen, Elizaveta Freinkman, Monther Abu-Remaileh, David M Sabatini. Cell 2015
665
67

Aspartate is an endogenous metabolic limitation for tumour growth.
Lucas B Sullivan, Alba Luengo, Laura V Danai, Lauren N Bush, Frances F Diehl, Aaron M Hosios, Allison N Lau, Sarah Elmiligy, Scott Malstrom, Caroline A Lewis,[...]. Nat Cell Biol 2018
151
21

Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours.
Javier Garcia-Bermudez, Lou Baudrier, Konnor La, Xiphias Ge Zhu, Justine Fidelin, Vladislav O Sviderskiy, Thales Papagiannakopoulos, Henrik Molina, Matija Snuderl, Caroline A Lewis,[...]. Nat Cell Biol 2018
169
18

Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin.
Dan Y Gui, Lucas B Sullivan, Alba Luengo, Aaron M Hosios, Lauren N Bush, Nadege Gitego, Shawn M Davidson, Elizaveta Freinkman, Craig J Thomas, Matthew G Vander Heiden. Cell Metab 2016
188
15

Lactate Metabolism in Human Lung Tumors.
Brandon Faubert, Kevin Y Li, Ling Cai, Christopher T Hensley, Jiyeon Kim, Lauren G Zacharias, Chendong Yang, Quyen N Do, Sarah Doucette, Daniel Burguete,[...]. Cell 2017
559
15

Complementation of mitochondrial electron transport chain by manipulation of the NAD+/NADH ratio.
Denis V Titov, Valentin Cracan, Russell P Goodman, Jun Peng, Zenon Grabarek, Vamsi K Mootha. Science 2016
175
13

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway.
Jaekyoung Son, Costas A Lyssiotis, Haoqiang Ying, Xiaoxu Wang, Sujun Hua, Matteo Ligorio, Rushika M Perera, Cristina R Ferrone, Edouard Mullarky, Ng Shyh-Chang,[...]. Nature 2013
12

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis.
Ralph J DeBerardinis, Anthony Mancuso, Evgueni Daikhin, Ilana Nissim, Marc Yudkoff, Suzanne Wehrli, Craig B Thompson. Proc Natl Acad Sci U S A 2007
11

From Krebs to clinic: glutamine metabolism to cancer therapy.
Brian J Altman, Zachary E Stine, Chi V Dang. Nat Rev Cancer 2016
800
10

Fundamentals of cancer metabolism.
Ralph J DeBerardinis, Navdeep S Chandel. Sci Adv 2016
10

Understanding the Warburg effect: the metabolic requirements of cell proliferation.
Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
10

Reductive carboxylation supports growth in tumour cells with defective mitochondria.
Andrew R Mullen, William W Wheaton, Eunsook S Jin, Pei-Hsuan Chen, Lucas B Sullivan, Tzuling Cheng, Youfeng Yang, W Marston Linehan, Navdeep S Chandel, Ralph J DeBerardinis. Nature 2011
846
9

Understanding the Intersections between Metabolism and Cancer Biology.
Matthew G Vander Heiden, Ralph J DeBerardinis. Cell 2017
996
9

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
8

Regulation of mammalian nucleotide metabolism and biosynthesis.
Andrew N Lane, Teresa W-M Fan. Nucleic Acids Res 2015
372
8

An inhibitor of oxidative phosphorylation exploits cancer vulnerability.
Jennifer R Molina, Yuting Sun, Marina Protopopova, Sonal Gera, Madhavi Bandi, Christopher Bristow, Timothy McAfoos, Pietro Morlacchi, Jeffrey Ackroyd, Ahmed-Noor A Agip,[...]. Nat Med 2018
360
8

Cellular redox state constrains serine synthesis and nucleotide production to impact cell proliferation.
Frances F Diehl, Caroline A Lewis, Brian P Fiske, Matthew G Vander Heiden. Nat Metab 2019
59
13


Aerobic glycolysis: meeting the metabolic requirements of cell proliferation.
Sophia Y Lunt, Matthew G Vander Heiden. Annu Rev Cell Dev Biol 2011
8

Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.
Cristovão M Sousa, Douglas E Biancur, Xiaoxu Wang, Christopher J Halbrook, Mara H Sherman, Li Zhang, Daniel Kremer, Rosa F Hwang, Agnes K Witkiewicz, Haoqiang Ying,[...]. Nature 2016
569
8

Increased demand for NAD+ relative to ATP drives aerobic glycolysis.
Alba Luengo, Zhaoqi Li, Dan Y Gui, Lucas B Sullivan, Maria Zagorulya, Brian T Do, Raphael Ferreira, Adi Naamati, Ahmed Ali, Caroline A Lewis,[...]. Mol Cell 2021
63
12

The Emerging Hallmarks of Cancer Metabolism.
Natalya N Pavlova, Craig B Thompson. Cell Metab 2016
7

Tumor-Stroma Mechanics Coordinate Amino Acid Availability to Sustain Tumor Growth and Malignancy.
Thomas Bertero, William M Oldham, Eloise M Grasset, Isabelle Bourget, Etienne Boulter, Sabrina Pisano, Paul Hofman, Floriant Bellvert, Guerrino Meneguzzi, Dmitry V Bulavin,[...]. Cell Metab 2019
130
7

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia.
Christian M Metallo, Paulo A Gameiro, Eric L Bell, Katherine R Mattaini, Juanjuan Yang, Karsten Hiller, Christopher M Jewell, Zachary R Johnson, Darrell J Irvine, Leonard Guarente,[...]. Nature 2011
7

On the origin of cancer cells.
O WARBURG. Science 1956
7

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.
Aravind Subramanian, Pablo Tamayo, Vamsi K Mootha, Sayan Mukherjee, Benjamin L Ebert, Michael A Gillette, Amanda Paulovich, Scott L Pomeroy, Todd R Golub, Eric S Lander,[...]. Proc Natl Acad Sci U S A 2005
7

Reductive carboxylation supports redox homeostasis during anchorage-independent growth.
Lei Jiang, Alexander A Shestov, Pamela Swain, Chendong Yang, Seth J Parker, Qiong A Wang, Lance S Terada, Nicholas D Adams, Michael T McCabe, Beth Pietrak,[...]. Nature 2016
322
7

Glucose feeds the TCA cycle via circulating lactate.
Sheng Hui, Jonathan M Ghergurovich, Raphael J Morscher, Cholsoon Jang, Xin Teng, Wenyun Lu, Lourdes A Esparza, Tannishtha Reya, Le Zhan, Jessie Yanxiang Guo,[...]. Nature 2017
602
7

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function.
Andrea Viale, Piergiorgio Pettazzoni, Costas A Lyssiotis, Haoqiang Ying, Nora Sánchez, Matteo Marchesini, Alessandro Carugo, Tessa Green, Sahil Seth, Virginia Giuliani,[...]. Nature 2014
732
7

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity.
Frank Weinberg, Robert Hamanaka, William W Wheaton, Samuel Weinberg, Joy Joseph, Marcos Lopez, Balaraman Kalyanaraman, Gökhan M Mutlu, G R Scott Budinger, Navdeep S Chandel. Proc Natl Acad Sci U S A 2010
7

Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis.
William W Wheaton, Samuel E Weinberg, Robert B Hamanaka, Saul Soberanes, Lucas B Sullivan, Elena Anso, Andrea Glasauer, Eric Dufour, Gokhan M Mutlu, Gr Scott Budigner,[...]. Elife 2014
637
7

The Warburg Effect: How Does it Benefit Cancer Cells?
Maria V Liberti, Jason W Locasale. Trends Biochem Sci 2016
7

PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis.
Valerie S LeBleu, Joyce T O'Connell, Karina N Gonzalez Herrera, Harriet Wikman, Klaus Pantel, Marcia C Haigis, Fernanda Machado de Carvalho, Aline Damascena, Ludmilla Thome Domingos Chinen, Rafael M Rocha,[...]. Nat Cell Biol 2014
772
7

Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment.
Zachary T Schafer, Alexandra R Grassian, Loling Song, Zhenyang Jiang, Zachary Gerhart-Hines, Hanna Y Irie, Sizhen Gao, Pere Puigserver, Joan S Brugge. Nature 2009
704
7

Metabolic reprogramming and cancer progression.
Brandon Faubert, Ashley Solmonson, Ralph J DeBerardinis. Science 2020
394
7

Mitochondrial TCA cycle metabolites control physiology and disease.
Inmaculada Martínez-Reyes, Navdeep S Chandel. Nat Commun 2020
486
7

Mitochondrial ubiquinol oxidation is necessary for tumour growth.
Inmaculada Martínez-Reyes, Luzivette Robles Cardona, Hyewon Kong, Karthik Vasan, Gregory S McElroy, Marie Werner, Hermon Kihshen, Colleen R Reczek, Samuel E Weinberg, Peng Gao,[...]. Nature 2020
72
9


Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells.
Aaron M Hosios, Vivian C Hecht, Laura V Danai, Marc O Johnson, Jeffrey C Rathmell, Matthew L Steinhauser, Scott R Manalis, Matthew G Vander Heiden. Dev Cell 2016
314
6

The key role of anaplerosis and cataplerosis for citric acid cycle function.
Oliver E Owen, Satish C Kalhan, Richard W Hanson. J Biol Chem 2002
686
6

Mitochondrial complex III is necessary for endothelial cell proliferation during angiogenesis.
Lauren P Diebold, Hyea Jin Gil, Peng Gao, Carlos A Martinez, Samuel E Weinberg, Navdeep S Chandel. Nat Metab 2019
78
7

Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein.
Jurre J Kamphorst, Michel Nofal, Cosimo Commisso, Sean R Hackett, Wenyun Lu, Elda Grabocka, Matthew G Vander Heiden, George Miller, Jeffrey A Drebin, Dafna Bar-Sagi,[...]. Cancer Res 2015
445
6

Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting.
H Furkan Alkan, Katharina E Walter, Alba Luengo, Corina T Madreiter-Sokolowski, Sarah Stryeck, Allison N Lau, Wael Al-Zoughbi, Caroline A Lewis, Craig J Thomas, Gerald Hoefler,[...]. Cell Metab 2018
80
7

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.
Ping-Chih Ho, Jessica Dauz Bihuniak, Andrew N Macintyre, Matthew Staron, Xiaojing Liu, Robert Amezquita, Yao-Chen Tsui, Guoliang Cui, Goran Micevic, Jose C Perales,[...]. Cell 2015
733
6

The redox requirements of proliferating mammalian cells.
Aaron M Hosios, Matthew G Vander Heiden. J Biol Chem 2018
58
10

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer.
Richard Possemato, Kevin M Marks, Yoav D Shaul, Michael E Pacold, Dohoon Kim, Kıvanç Birsoy, Shalini Sethumadhavan, Hin-Koon Woo, Hyun G Jang, Abhishek K Jha,[...]. Nature 2011
6

The multifaceted contributions of mitochondria to cellular metabolism.
Jessica B Spinelli, Marcia C Haigis. Nat Cell Biol 2018
427
6

Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion.
Robert D Leone, Liang Zhao, Judson M Englert, Im-Meng Sun, Min-Hee Oh, Im-Hong Sun, Matthew L Arwood, Ian A Bettencourt, Chirag H Patel, Jiayu Wen,[...]. Science 2019
311
6

We need to talk about the Warburg effect.
Ralph J DeBerardinis, Navdeep S Chandel. Nat Metab 2020
200
6

Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells.
Bryce W Carey, Lydia W S Finley, Justin R Cross, C David Allis, Craig B Thompson. Nature 2015
550
6


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.