A citation-based method for searching scientific literature

James B Stewart, Patrick F Chinnery. Nat Rev Genet 2015
Times Cited: 322







List of co-cited articles
1179 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Mitochondrial DNA genetics and the heteroplasmy conundrum in evolution and disease.
Douglas C Wallace, Dimitra Chalkia. Cold Spring Harb Perspect Biol 2013
308
26

Prevalence of nuclear and mitochondrial DNA mutations related to adult mitochondrial disease.
Gráinne S Gorman, Andrew M Schaefer, Yi Ng, Nicholas Gomez, Emma L Blakely, Charlotte L Alston, Catherine Feeney, Rita Horvath, Patrick Yu-Wai-Man, Patrick F Chinnery,[...]. Ann Neurol 2015
362
16

Heteroplasmy of mouse mtDNA is genetically unstable and results in altered behavior and cognition.
Mark S Sharpley, Christine Marciniak, Kristin Eckel-Mahan, Meagan McManus, Marco Crimi, Katrina Waymire, Chun Shi Lin, Satoru Masubuchi, Nicole Friend, Maya Koike,[...]. Cell 2012
212
16

Premature ageing in mice expressing defective mitochondrial DNA polymerase.
Aleksandra Trifunovic, Anna Wredenberg, Maria Falkenberg, Johannes N Spelbrink, Anja T Rovio, Carl E Bruder, Mohammad Bohlooly-Y, Sebastian Gidlöf, Anders Oldfors, Rolf Wibom,[...]. Nature 2004
15

Germline selection shapes human mitochondrial DNA diversity.
Wei Wei, Salih Tuna, Michael J Keogh, Katherine R Smith, Timothy J Aitman, Phil L Beales, David L Bennett, Daniel P Gale, Maria A K Bitner-Glindzicz, Graeme C Black,[...]. Science 2019
58
25

Biparental Inheritance of Mitochondrial DNA in Humans.
Shiyu Luo, C Alexander Valencia, Jinglan Zhang, Ni-Chung Lee, Jesse Slone, Baoheng Gui, Xinjian Wang, Zhuo Li, Sarah Dell, Jenice Brown,[...]. Proc Natl Acad Sci U S A 2018
129
14

Mitochondrial DNA mutations in human disease.
Robert W Taylor, Doug M Turnbull. Nat Rev Genet 2005
14

Sequence and organization of the human mitochondrial genome.
S Anderson, A T Bankier, B G Barrell, M H de Bruijn, A R Coulson, J Drouin, I C Eperon, D P Nierlich, B A Roe, F Sanger,[...]. Nature 1981
13

Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo.
Payam A Gammage, Carlo Viscomi, Marie-Lune Simard, Ana S H Costa, Edoardo Gaude, Christopher A Powell, Lindsey Van Haute, Beverly J McCann, Pedro Rebelo-Guiomar, Raffaele Cerutti,[...]. Nat Med 2018
93
12

Mitochondrial diseases.
Gráinne S Gorman, Patrick F Chinnery, Salvatore DiMauro, Michio Hirano, Yasutoshi Koga, Robert McFarland, Anu Suomalainen, David R Thorburn, Massimo Zeviani, Douglass M Turnbull. Nat Rev Dis Primers 2016
369
12

Universal heteroplasmy of human mitochondrial DNA.
Brendan A I Payne, Ian J Wilson, Patrick Yu-Wai-Man, Jonathan Coxhead, David Deehan, Rita Horvath, Robert W Taylor, David C Samuels, Mauro Santibanez-Koref, Patrick F Chinnery. Hum Mol Genet 2013
224
11

mtDNA Variation and Analysis Using Mitomap and Mitomaster.
Marie T Lott, Jeremy N Leipzig, Olga Derbeneva, H Michael Xie, Dimitra Chalkia, Mahdi Sarmady, Vincent Procaccio, Douglas C Wallace. Curr Protoc Bioinformatics 2013
216
11

A reduction of mitochondrial DNA molecules during embryogenesis explains the rapid segregation of genotypes.
Lynsey M Cree, David C Samuels, Susana Chuva de Sousa Lopes, Harsha Karur Rajasimha, Passorn Wonnapinij, Jeffrey R Mann, Hans-Henrik M Dahl, Patrick F Chinnery. Nat Genet 2008
307
11

MitoTALEN reduces mutant mtDNA load and restores tRNAAla levels in a mouse model of heteroplasmic mtDNA mutation.
Sandra R Bacman, Johanna H K Kauppila, Claudia V Pereira, Nadee Nissanka, Maria Miranda, Milena Pinto, Sion L Williams, Nils-Göran Larsson, James B Stewart, Carlos T Moraes. Nat Med 2018
80
13


Linear mitochondrial DNA is rapidly degraded by components of the replication machinery.
Viktoriya Peeva, Daniel Blei, Genevieve Trombly, Sarah Corsi, Maciej J Szukszto, Pedro Rebelo-Guiomar, Payam A Gammage, Alexei P Kudin, Christian Becker, Janine Altmüller,[...]. Nat Commun 2018
56
17

mtDNA heteroplasmy level and copy number indicate disease burden in m.3243A>G mitochondrial disease.
John P Grady, Sarah J Pickett, Yi Shiau Ng, Charlotte L Alston, Emma L Blakely, Steven A Hardy, Catherine L Feeney, Alexandra A Bright, Andrew M Schaefer, Gráinne S Gorman,[...]. EMBO Mol Med 2018
79
12

Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos.
Vasileios I Floros, Angela Pyle, Sabine Dietmann, Wei Wei, Walfred C W Tang, Naoko Irie, Brendan Payne, Antonio Capalbo, Laila Noli, Jonathan Coxhead,[...]. Nat Cell Biol 2018
62
16

Strong purifying selection in transmission of mammalian mitochondrial DNA.
James Bruce Stewart, Christoph Freyer, Joanna L Elson, Anna Wredenberg, Zekiye Cansu, Aleksandra Trifunovic, Nils-Göran Larsson. PLoS Biol 2008
312
10

A mouse model of mitochondrial disease reveals germline selection against severe mtDNA mutations.
Weiwei Fan, Katrina G Waymire, Navneet Narula, Peng Li, Christophe Rocher, Pinar E Coskun, Mani A Vannan, Jagat Narula, Grant R Macgregor, Douglas C Wallace. Science 2008
289
10

Heteroplasmic mitochondrial DNA mutations in normal and tumour cells.
Yiping He, Jian Wu, Devin C Dressman, Christine Iacobuzio-Donahue, Sanford D Markowitz, Victor E Velculescu, Luis A Diaz, Kenneth W Kinzler, Bert Vogelstein, Nickolas Papadopoulos. Nature 2010
359
10

Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease.
Louise A Hyslop, Paul Blakeley, Lyndsey Craven, Jessica Richardson, Norah M E Fogarty, Elpida Fragouli, Mahdi Lamb, Sissy E Wamaitha, Nilendran Prathalingam, Qi Zhang,[...]. Nature 2016
154
10

Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing.
Ana Latorre-Pellicer, Raquel Moreno-Loshuertos, Ana Victoria Lechuga-Vieco, Fátima Sánchez-Cabo, Carlos Torroja, Rebeca Acín-Pérez, Enrique Calvo, Esther Aix, Andrés González-Guerra, Angela Logan,[...]. Nature 2016
192
10

Regulation of Mother-to-Offspring Transmission of mtDNA Heteroplasmy.
Ana Latorre-Pellicer, Ana Victoria Lechuga-Vieco, Iain G Johnston, Riikka H Hämäläinen, Juan Pellico, Raquel Justo-Méndez, Jose María Fernández-Toro, Cristina Clavería, Adela Guaras, Rocío Sierra,[...]. Cell Metab 2019
24
41

Specific elimination of mutant mitochondrial genomes in patient-derived cells by mitoTALENs.
Sandra R Bacman, Siôn L Williams, Milena Pinto, Susana Peralta, Carlos T Moraes. Nat Med 2013
204
9

Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations.
Eunju Kang, Jun Wu, Nuria Marti Gutierrez, Amy Koski, Rebecca Tippner-Hedges, Karen Agaronyan, Aida Platero-Luengo, Paloma Martinez-Redondo, Hong Ma, Yeonmi Lee,[...]. Nature 2016
125
9

Extensive tissue-related and allele-related mtDNA heteroplasmy suggests positive selection for somatic mutations.
Mingkun Li, Roland Schröder, Shengyu Ni, Burkhard Madea, Mark Stoneking. Proc Natl Acad Sci U S A 2015
94
9

MitoCarta2.0: an updated inventory of mammalian mitochondrial proteins.
Sarah E Calvo, Karl R Clauser, Vamsi K Mootha. Nucleic Acids Res 2016
686
9

Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission.
Christoph Freyer, Lynsey M Cree, Arnaud Mourier, James B Stewart, Camilla Koolmeister, Dusanka Milenkovic, Timothy Wai, Vasileios I Floros, Erik Hagström, Emmanouella E Chatzidaki,[...]. Nat Genet 2012
85
10

A Phenotype-Driven Approach to Generate Mouse Models with Pathogenic mtDNA Mutations Causing Mitochondrial Disease.
Johanna H K Kauppila, Holly L Baines, Ana Bratic, Marie-Lune Simard, Christoph Freyer, Arnaud Mourier, Craig Stamp, Roberta Filograna, Nils-Göran Larsson, Laura C Greaves,[...]. Cell Rep 2016
50
18


A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing.
Beverly Y Mok, Marcos H de Moraes, Jun Zeng, Dustin E Bosch, Anna V Kotrys, Aditya Raguram, FoSheng Hsu, Matthew C Radey, S Brook Peterson, Vamsi K Mootha,[...]. Nature 2020
71
12

Mitochondrial Heterogeneity.
Juvid Aryaman, Iain G Johnston, Nick S Jones. Front Genet 2019
29
27

Maintenance and propagation of a deleterious mitochondrial genome by the mitochondrial unfolded protein response.
Yi-Fan Lin, Anna M Schulz, Mark W Pellegrino, Yun Lu, Shai Shaham, Cole M Haynes. Nature 2016
119
8

Homeostatic Responses Regulate Selfish Mitochondrial Genome Dynamics in C. elegans.
Bryan L Gitschlag, Cait S Kirby, David C Samuels, Rama D Gangula, Simon A Mallal, Maulik R Patel. Cell Metab 2016
65
12

High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease.
Andreas Bender, Kim J Krishnan, Christopher M Morris, Geoffrey A Taylor, Amy K Reeve, Robert H Perry, Evelyn Jaros, Joshua S Hersheson, Joanne Betts, Thomas Klopstock,[...]. Nat Genet 2006
950
8

The mitochondrial DNA genetic bottleneck: inheritance and beyond.
Haixin Zhang, Stephen P Burr, Patrick F Chinnery. Essays Biochem 2018
29
27

Germline mitochondrial DNA mutations aggravate ageing and can impair brain development.
Jaime M Ross, James B Stewart, Erik Hagström, Stefan Brené, Arnaud Mourier, Giuseppe Coppotelli, Christoph Freyer, Marie Lagouge, Barry J Hoffer, Lars Olson,[...]. Nature 2013
167
8




MtDNA segregation in heteroplasmic tissues is common in vivo and modulated by haplotype differences and developmental stage.
Joerg Patrick Burgstaller, Iain G Johnston, Nick S Jones, Jana Albrechtová, Thomas Kolbe, Claus Vogl, Andreas Futschik, Corina Mayrhofer, Dieter Klein, Sonja Sabitzer,[...]. Cell Rep 2014
62
11

Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA.
Christian Kukat, Christian A Wurm, Henrik Spåhr, Maria Falkenberg, Nils-Göran Larsson, Stefan Jakobs. Proc Natl Acad Sci U S A 2011
277
7

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy.
Derek Narendra, Atsushi Tanaka, Der-Fen Suen, Richard J Youle. J Cell Biol 2008
7

Selective elimination of mitochondrial mutations in the germline by genome editing.
Pradeep Reddy, Alejandro Ocampo, Keiichiro Suzuki, Jinping Luo, Sandra R Bacman, Sion L Williams, Atsushi Sugawara, Daiji Okamura, Yuji Tsunekawa, Jun Wu,[...]. Cell 2015
142
7

Mitochondrially targeted ZFNs for selective degradation of pathogenic mitochondrial genomes bearing large-scale deletions or point mutations.
Payam A Gammage, Joanna Rorbach, Anna I Vincent, Edward J Rebar, Michal Minczuk. EMBO Mol Med 2014
129
7


Paternal inheritance of mitochondrial DNA.
Marianne Schwartz, John Vissing. N Engl J Med 2002
339
7

Tissue- and cell-type-specific manifestations of heteroplasmic mtDNA 3243A>G mutation in human induced pluripotent stem cell-derived disease model.
Riikka H Hämäläinen, Tuula Manninen, Hanna Koivumäki, Mikhail Kislin, Timo Otonkoski, Anu Suomalainen. Proc Natl Acad Sci U S A 2013
125
7

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy.
Gilad Twig, Alvaro Elorza, Anthony J A Molina, Hibo Mohamed, Jakob D Wikstrom, Gil Walzer, Linsey Stiles, Sarah E Haigh, Steve Katz, Guy Las,[...]. EMBO J 2008
7


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.