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Times Cited: 556
Times Cited: 556
Times Cited
Times Co-cited
Similarity
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9.
John G Doench, Nicolo Fusi, Meagan Sullender, Mudra Hegde, Emma W Vaimberg, Katherine F Donovan, Ian Smith, Zuzana Tothova, Craig Wilen, Robert Orchard,[...]. Nat Biotechnol 2016
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A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.
Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier. Science 2012
Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier. Science 2012
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Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.
John G Doench, Ella Hartenian, Daniel B Graham, Zuzana Tothova, Mudra Hegde, Ian Smith, Meagan Sullender, Benjamin L Ebert, Ramnik J Xavier, David E Root. Nat Biotechnol 2014
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Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR.
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DNA targeting specificity of RNA-guided Cas9 nucleases.
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Genetic screens in human cells using the CRISPR-Cas9 system.
Tim Wang, Jenny J Wei, David M Sabatini, Eric S Lander. Science 2014
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Multiplex genome engineering using CRISPR/Cas systems.
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Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system.
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Easy quantitative assessment of genome editing by sequence trace decomposition.
Eva K Brinkman, Tao Chen, Mario Amendola, Bas van Steensel. Nucleic Acids Res 2014
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Unraveling CRISPR-Cas9 genome engineering parameters via a library-on-library approach.
Raj Chari, Prashant Mali, Mark Moosburner, George M Church. Nat Methods 2015
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Search-and-replace genome editing without double-strand breaks or donor DNA.
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WU-CRISPR: characteristics of functional guide RNAs for the CRISPR/Cas9 system.
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CHOPCHOP v3: expanding the CRISPR web toolbox beyond genome editing.
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Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage.
Alexis C Komor, Yongjoo B Kim, Michael S Packer, John A Zuris, David R Liu. Nature 2016
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Efficient genome editing in zebrafish using a CRISPR-Cas system.
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Highly Efficient CRISPR-Cas9-Based Methods for Generating Deletion Mutations and F0 Embryos that Lack Gene Function in Zebrafish.
Kazuyuki Hoshijima, Michael J Jurynec, Dana Klatt Shaw, Ashley M Jacobi, Mark A Behlke, David Jonah Grunwald. Dev Cell 2019
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Efficient mutagenesis by Cas9 protein-mediated oligonucleotide insertion and large-scale assessment of single-guide RNAs.
James A Gagnon, Eivind Valen, Summer B Thyme, Peng Huang, Laila Akhmetova, Andrea Pauli, Tessa G Montague, Steven Zimmerman, Constance Richter, Alexander F Schier. PLoS One 2014
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High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells.
Yanfang Fu, Jennifer A Foden, Cyd Khayter, Morgan L Maeder, Deepak Reyon, J Keith Joung, Jeffry D Sander. Nat Biotechnol 2013
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A Rapid Method for Directed Gene Knockout for Screening in G0 Zebrafish.
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The Sequence Alignment/Map format and SAMtools.
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E-CRISP: fast CRISPR target site identification.
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RNA-guided human genome engineering via Cas9.
Prashant Mali, Luhan Yang, Kevin M Esvelt, John Aach, Marc Guell, James E DiCarlo, Julie E Norville, George M Church. Science 2013
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Predictable and precise template-free CRISPR editing of pathogenic variants.
Max W Shen, Mandana Arbab, Jonathan Y Hsu, Daniel Worstell, Sannie J Culbertson, Olga Krabbe, Christopher A Cassa, David R Liu, David K Gifford, Richard I Sherwood. Nature 2018
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DeepCRISPR: optimized CRISPR guide RNA design by deep learning.
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GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases.
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Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases.
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Optimized CRISPR guide RNA design for two high-fidelity Cas9 variants by deep learning.
Daqi Wang, Chengdong Zhang, Bei Wang, Bin Li, Qiang Wang, Dong Liu, Hongyan Wang, Yan Zhou, Leming Shi, Feng Lan,[...]. Nat Commun 2019
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Genome-scale CRISPR-Cas9 knockout screening in human cells.
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Prediction of off-target activities for the end-to-end design of CRISPR guide RNAs.
Jennifer Listgarten, Michael Weinstein, Benjamin P Kleinstiver, Alexander A Sousa, J Keith Joung, Jake Crawford, Kevin Gao, Luong Hoang, Melih Elibol, John G Doench,[...]. Nat Biomed Eng 2018
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High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity.
Vikram Pattanayak, Steven Lin, John P Guilinger, Enbo Ma, Jennifer A Doudna, David R Liu. Nat Biotechnol 2013
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CCTop: An Intuitive, Flexible and Reliable CRISPR/Cas9 Target Prediction Tool.
Manuel Stemmer, Thomas Thumberger, Maria Del Sol Keyer, Joachim Wittbrodt, Juan L Mateo. PLoS One 2015
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CHOPCHOP v2: a web tool for the next generation of CRISPR genome engineering.
Kornel Labun, Tessa G Montague, James A Gagnon, Summer B Thyme, Eivind Valen. Nucleic Acids Res 2016
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SpCas9 activity prediction by DeepSpCas9, a deep learning-based model with high generalization performance.
Hui Kwon Kim, Younggwang Kim, Sungtae Lee, Seonwoo Min, Jung Yoon Bae, Jae Woo Choi, Jinman Park, Dongmin Jung, Sungroh Yoon, Hyongbum Henry Kim. Sci Adv 2019
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High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9.
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Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity.
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DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.
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Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.
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High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.
Benjamin P Kleinstiver, Vikram Pattanayak, Michelle S Prew, Shengdar Q Tsai, Nhu T Nguyen, Zongli Zheng, J Keith Joung. Nature 2016
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Maximizing mutagenesis with solubilized CRISPR-Cas9 ribonucleoprotein complexes.
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High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.
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Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation.
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Refined sgRNA efficacy prediction improves large- and small-scale CRISPR-Cas9 applications.
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Engineered CRISPR-Cas9 nucleases with altered PAM specificities.
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Crystal structure of Cas9 in complex with guide RNA and target DNA.
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Improving CRISPR-Cas nuclease specificity using truncated guide RNAs.
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8
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.