A citation-based method for searching scientific literature

Yuka Atagi, Chia-Chen Liu, Meghan M Painter, Xiao-Fen Chen, Christophe Verbeeck, Honghua Zheng, Xia Li, Rosa Rademakers, Silvia S Kang, Huaxi Xu, Steven Younkin, Pritam Das, John D Fryer, Guojun Bu. J Biol Chem 2015
Times Cited: 276







List of co-cited articles
1588 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease.
Hadas Keren-Shaul, Amit Spinrad, Assaf Weiner, Orit Matcovitch-Natan, Raz Dvir-Szternfeld, Tyler K Ulland, Eyal David, Kuti Baruch, David Lara-Astaiso, Beata Toth,[...]. Cell 2017
63


TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model.
Yaming Wang, Marina Cella, Kaitlin Mallinson, Jason D Ulrich, Katherine L Young, Michelle L Robinette, Susan Gilfillan, Gokul M Krishnan, Shwetha Sudhakar, Bernd H Zinselmeyer,[...]. Cell 2015
868
53

Variant of TREM2 associated with the risk of Alzheimer's disease.
Thorlakur Jonsson, Hreinn Stefansson, Stacy Steinberg, Ingileif Jonsdottir, Palmi V Jonsson, Jon Snaedal, Sigurbjorn Bjornsson, Johanna Huttenlocher, Allan I Levey, James J Lah,[...]. N Engl J Med 2013
52

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases.
Susanne Krasemann, Charlotte Madore, Ron Cialic, Caroline Baufeld, Narghes Calcagno, Rachid El Fatimy, Lien Beckers, Elaine O'Loughlin, Yang Xu, Zain Fanek,[...]. Immunity 2017
50

TREM2 variants in Alzheimer's disease.
Rita Guerreiro, Aleksandra Wojtas, Jose Bras, Minerva Carrasquillo, Ekaterina Rogaeva, Elisa Majounie, Carlos Cruchaga, Celeste Sassi, John S K Kauwe, Steven Younkin,[...]. N Engl J Med 2013
46

The Triggering Receptor Expressed on Myeloid Cells 2 Binds Apolipoprotein E.
Charles C Bailey, Lindsey B DeVaux, Michael Farzan. J Biol Chem 2015
173
41

TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques.
Yaming Wang, Tyler K Ulland, Jason D Ulrich, Wilbur Song, John A Tzaferis, Justin T Hole, Peng Yuan, Thomas E Mahan, Yang Shi, Susan Gilfillan,[...]. J Exp Med 2016
394
31

TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease.
Tyler K Ulland, Wilbur M Song, Stanley Ching-Cheng Huang, Jason D Ulrich, Alexey Sergushichev, Wandy L Beatty, Alexander A Loboda, Yingyue Zhou, Nigel J Cairns, Amal Kambal,[...]. Cell 2017
493
28

TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function.
Yingjun Zhao, Xilin Wu, Xiaoguang Li, Lu-Lin Jiang, Xun Gui, Yan Liu, Yu Sun, Bing Zhu, Juan C Piña-Crespo, Muxian Zhang,[...]. Neuron 2018
289
28

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families.
E H Corder, A M Saunders, W J Strittmatter, D E Schmechel, P C Gaskell, G W Small, A D Roses, J L Haines, M A Pericak-Vance. Science 1993
26

TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge.
Alicia A Nugent, Karin Lin, Bettina van Lengerich, Steve Lianoglou, Laralynne Przybyla, Sonnet S Davis, Ceyda Llapashtica, Junhua Wang, Do Jin Kim, Dan Xia,[...]. Neuron 2020
178
26

TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.
Peng Yuan, Carlo Condello, C Dirk Keene, Yaming Wang, Thomas D Bird, Steven M Paul, Wenjie Luo, Marco Colonna, David Baddeley, Jaime Grutzendler. Neuron 2016
328
25


TREM2 sustains microglial expansion during aging and response to demyelination.
Pietro Luigi Poliani, Yaming Wang, Elena Fontana, Michelle L Robinette, Yoshinori Yamanishi, Susan Gilfillan, Marco Colonna. J Clin Invest 2015
273
21

TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis.
Gernot Kleinberger, Yoshinori Yamanishi, Marc Suárez-Calvet, Eva Czirr, Ebba Lohmann, Elise Cuyvers, Hanne Struyfs, Nadine Pettkus, Andrea Wenninger-Weinzierl, Fargol Mazaheri,[...]. Sci Transl Med 2014
452
20

Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE.
Samira Parhizkar, Thomas Arzberger, Matthias Brendel, Gernot Kleinberger, Maximilian Deussing, Carola Focke, Brigitte Nuscher, Monica Xiong, Alireza Ghasemigharagoz, Natalie Katzmarski,[...]. Nat Neurosci 2019
222
19

Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes.
Timothy R Hammond, Connor Dufort, Lasse Dissing-Olesen, Stefanie Giera, Adam Young, Alec Wysoker, Alec J Walker, Frederick Gergits, Michael Segel, James Nemesh,[...]. Immunity 2019
730
19

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.
Yang Shi, Kaoru Yamada, Shane Antony Liddelow, Scott T Smith, Lingzhi Zhao, Wenjie Luo, Richard M Tsai, Salvatore Spina, Lea T Grinberg, Julio C Rojas,[...]. Nature 2017
541
19

Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease.
Taylor R Jay, Anna M Hirsch, Margaret L Broihier, Crystal M Miller, Lee E Neilson, Richard M Ransohoff, Bruce T Lamb, Gary E Landreth. J Neurosci 2017
236
18

TREM2- and DAP12-dependent activation of PI3K requires DAP10 and is inhibited by SHIP1.
Qisheng Peng, Shikha Malhotra, James A Torchia, William G Kerr, K Mark Coggeshall, Mary Beth Humphrey. Sci Signal 2010
203
18

Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region.
Kai Schlepckow, Kathryn M Monroe, Gernot Kleinberger, Ludovico Cantuti-Castelvetri, Samira Parhizkar, Dan Xia, Michael Willem, Georg Werner, Nadine Pettkus, Bettina Brunner,[...]. EMBO Mol Med 2020
82
21

Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype.
Juha Paloneva, Tuula Manninen, Grant Christman, Karine Hovanes, Jami Mandelin, Rolf Adolfsson, Marino Bianchin, Thomas Bird, Roxana Miranda, Andrea Salmaggi,[...]. Am J Hum Genet 2002
480
17

Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms.
Daniel L Kober, Jennifer M Alexander-Brett, Celeste M Karch, Carlos Cruchaga, Marco Colonna, Michael J Holtzman, Thomas J Brett. Elife 2016
101
17

TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models.
Taylor R Jay, Crystal M Miller, Paul J Cheng, Leah C Graham, Shane Bemiller, Margaret L Broihier, Guixiang Xu, Daniel Margevicius, J Colleen Karlo, Gregory L Sousa,[...]. J Exp Med 2015
427
17

TREM2 Acts Downstream of CD33 in Modulating Microglial Pathology in Alzheimer's Disease.
Ana Griciuc, Shaun Patel, Anthony N Federico, Se Hoon Choi, Brendan J Innes, Mary K Oram, Gea Cereghetti, Danielle McGinty, Anthony Anselmo, Ruslan I Sadreyev,[...]. Neuron 2019
134
17

ApoE facilitates the microglial response to amyloid plaque pathology.
Jason D Ulrich, Tyler K Ulland, Thomas E Mahan, Sofie Nyström, K Peter Nilsson, Wilbur M Song, Yingyue Zhou, Mariska Reinartz, Seulah Choi, Hong Jiang,[...]. J Exp Med 2018
120
17

Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer's disease model.
Shoutang Wang, Meer Mustafa, Carla M Yuede, Santiago Viveros Salazar, Philip Kong, Hua Long, Michael Ward, Omer Siddiqui, Robert Paul, Susan Gilfillan,[...]. J Exp Med 2020
106
17

Alzheimer's disease-associated TREM2 variants exhibit either decreased or increased ligand-dependent activation.
Wilbur Song, Basavaraj Hooli, Kristina Mullin, Sheng Chih Jin, Marina Cella, Tyler K Ulland, Yaming Wang, Rudolph E Tanzi, Marco Colonna. Alzheimers Dement 2017
122
17

Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques.
Carlo Condello, Peng Yuan, Aaron Schain, Jaime Grutzendler. Nat Commun 2015
296
17

Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain.
Julia Marschallinger, Tal Iram, Macy Zardeneta, Song E Lee, Benoit Lehallier, Michael S Haney, John V Pluvinage, Vidhu Mathur, Oliver Hahn, David W Morgens,[...]. Nat Neurosci 2020
258
17

The Major Risk Factors for Alzheimer's Disease: Age, Sex, and Genes Modulate the Microglia Response to Aβ Plaques.
Carlo Sala Frigerio, Leen Wolfs, Nicola Fattorelli, Nicola Thrupp, Iryna Voytyuk, Inga Schmidt, Renzo Mancuso, Wei-Ting Chen, Maya E Woodbury, Gyan Srivastava,[...]. Cell Rep 2019
244
16

Cutting edge: TREM-2 attenuates macrophage activation.
Isaiah R Turnbull, Susan Gilfillan, Marina Cella, Taiki Aoshi, Mark Miller, Laura Piccio, Maristela Hernandez, Marco Colonna. J Immunol 2006
443
16

Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration.
Aleksandra Deczkowska, Hadas Keren-Shaul, Assaf Weiner, Marco Colonna, Michal Schwartz, Ido Amit. Cell 2018
429
16

Single-cell transcriptomic analysis of Alzheimer's disease.
Hansruedi Mathys, Jose Davila-Velderrain, Zhuyu Peng, Fan Gao, Shahin Mohammadi, Jennie Z Young, Madhvi Menon, Liang He, Fatema Abdurrob, Xueqiao Jiang,[...]. Nature 2019
742
16

ApoE4 Accelerates Early Seeding of Amyloid Pathology.
Chia-Chen Liu, Na Zhao, Yuan Fu, Na Wang, Cynthia Linares, Chih-Wei Tsai, Guojun Bu. Neuron 2017
167
16


TREM2 function impedes tau seeding in neuritic plaques.
Cheryl E G Leyns, Maud Gratuze, Sneha Narasimhan, Nimansha Jain, Lauren J Koscal, Hong Jiang, Melissa Manis, Marco Colonna, Virginia M Y Lee, Jason D Ulrich,[...]. Nat Neurosci 2019
104
15

Microglia in Alzheimer's disease.
David V Hansen, Jesse E Hanson, Morgan Sheng. J Cell Biol 2018
657
15

Complement and microglia mediate early synapse loss in Alzheimer mouse models.
Soyon Hong, Victoria F Beja-Glasser, Bianca M Nfonoyim, Arnaud Frouin, Shaomin Li, Saranya Ramakrishnan, Katherine M Merry, Qiaoqiao Shi, Arnon Rosenthal, Ben A Barres,[...]. Science 2016
15

Humanized TREM2 mice reveal microglia-intrinsic and -extrinsic effects of R47H polymorphism.
Wilbur M Song, Satoru Joshita, Yingyue Zhou, Tyler K Ulland, Susan Gilfillan, Marco Colonna. J Exp Med 2018
122
15

APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer's Disease Phenotypes in Human iPSC-Derived Brain Cell Types.
Yuan-Ta Lin, Jinsoo Seo, Fan Gao, Heather M Feldman, Hsin-Lan Wen, Jay Penney, Hugh P Cam, Elizabeta Gjoneska, Waseem K Raja, Jemmie Cheng,[...]. Neuron 2018
369
14

Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models.
C Y Daniel Lee, Anthony Daggett, Xiaofeng Gu, Lu-Lin Jiang, Peter Langfelder, Xiaoguang Li, Nan Wang, Yingjun Zhao, Chang Sin Park, Yonatan Cooper,[...]. Neuron 2018
169
14

Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner.
Dorothy P Schafer, Emily K Lehrman, Amanda G Kautzman, Ryuta Koyama, Alan R Mardinly, Ryo Yamasaki, Richard M Ransohoff, Michael E Greenberg, Ben A Barres, Beth Stevens. Neuron 2012
14

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
J C Lambert, C A Ibrahim-Verbaas, D Harold, A C Naj, R Sims, C Bellenguez, A L DeStafano, J C Bis, G W Beecham, B Grenier-Boley,[...]. Nat Genet 2013
14

Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing.
Qingyun Li, Zuolin Cheng, Lu Zhou, Spyros Darmanis, Norma F Neff, Jennifer Okamoto, Gunsagar Gulati, Mariko L Bennett, Lu O Sun, Laura E Clarke,[...]. Neuron 2019
382
14

Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease.
Yingyue Zhou, Wilbur M Song, Prabhakar S Andhey, Amanda Swain, Tyler Levy, Kelly R Miller, Pietro L Poliani, Manuela Cominelli, Shikha Grover, Susan Gilfillan,[...]. Nat Med 2020
295
14

New insights into the role of TREM2 in Alzheimer's disease.
Maud Gratuze, Cheryl E G Leyns, David M Holtzman. Mol Neurodegener 2018
190
14

Neuroinflammation in Alzheimer's disease.
Michael T Heneka, Monica J Carson, Joseph El Khoury, Gary E Landreth, Frederic Brosseron, Douglas L Feinstein, Andreas H Jacobs, Tony Wyss-Coray, Javier Vitorica, Richard M Ransohoff,[...]. Lancet Neurol 2015
14



Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.