Agnel Sfeir, Lorraine S Symington. Trends Biochem Sci 2015
Times Cited: 297
Times Cited: 297
Times Cited
Times Co-cited
Similarity
Non-homologous DNA end joining and alternative pathways to double-strand break repair.
Howard H Y Chang, Nicholas R Pannunzio, Noritaka Adachi, Michael R Lieber. Nat Rev Mol Cell Biol 2017
Howard H Y Chang, Nicholas R Pannunzio, Noritaka Adachi, Michael R Lieber. Nat Rev Mol Cell Biol 2017
26
A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.
Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier. Science 2012
Martin Jinek, Krzysztof Chylinski, Ines Fonfara, Michael Hauer, Jennifer A Doudna, Emmanuelle Charpentier. Science 2012
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Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells.
Lan N Truong, Yongjiang Li, Linda Z Shi, Patty Yi-Hwa Hwang, Jing He, Hailong Wang, Niema Razavian, Michael W Berns, Xiaohua Wu. Proc Natl Acad Sci U S A 2013
Lan N Truong, Yongjiang Li, Linda Z Shi, Patty Yi-Hwa Hwang, Jing He, Hailong Wang, Niema Razavian, Michael W Berns, Xiaohua Wu. Proc Natl Acad Sci U S A 2013
23
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage.
Alexis C Komor, Yongjoo B Kim, Michael S Packer, John A Zuris, David R Liu. Nature 2016
Alexis C Komor, Yongjoo B Kim, Michael S Packer, John A Zuris, David R Liu. Nature 2016
18
Search-and-replace genome editing without double-strand breaks or donor DNA.
Andrew V Anzalone, Peyton B Randolph, Jessie R Davis, Alexander A Sousa, Luke W Koblan, Jonathan M Levy, Peter J Chen, Christopher Wilson, Gregory A Newby, Aditya Raguram,[...]. Nature 2019
Andrew V Anzalone, Peyton B Randolph, Jessie R Davis, Alexander A Sousa, Luke W Koblan, Jonathan M Levy, Peter J Chen, Christopher Wilson, Gregory A Newby, Aditya Raguram,[...]. Nature 2019
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Repair Pathway Choices and Consequences at the Double-Strand Break.
Raphael Ceccaldi, Beatrice Rondinelli, Alan D D'Andrea. Trends Cell Biol 2016
Raphael Ceccaldi, Beatrice Rondinelli, Alan D D'Andrea. Trends Cell Biol 2016
17
Advances in genome editing through control of DNA repair pathways.
Charles D Yeh, Christopher D Richardson, Jacob E Corn. Nat Cell Biol 2019
Charles D Yeh, Christopher D Richardson, Jacob E Corn. Nat Cell Biol 2019
17
Regulation of Single-Strand Annealing and its Role in Genome Maintenance.
Ragini Bhargava, David O Onyango, Jeremy M Stark. Trends Genet 2016
Ragini Bhargava, David O Onyango, Jeremy M Stark. Trends Genet 2016
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Microhomology-mediated end joining: Good, bad and ugly.
Ja-Hwan Seol, Eun Yong Shim, Sang Eun Lee. Mutat Res 2018
Ja-Hwan Seol, Eun Yong Shim, Sang Eun Lee. Mutat Res 2018
15
Repair of double-strand breaks induced by CRISPR-Cas9 leads to large deletions and complex rearrangements.
Michael Kosicki, Kärt Tomberg, Allan Bradley. Nat Biotechnol 2018
Michael Kosicki, Kärt Tomberg, Allan Bradley. Nat Biotechnol 2018
14
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.
Nicole M Gaudelli, Alexis C Komor, Holly A Rees, Michael S Packer, Ahmed H Badran, David I Bryson, David R Liu. Nature 2017
Nicole M Gaudelli, Alexis C Komor, Holly A Rees, Michael S Packer, Ahmed H Badran, David I Bryson, David R Liu. Nature 2017
14
DNA double-strand break repair-pathway choice in somatic mammalian cells.
Ralph Scully, Arvind Panday, Rajula Elango, Nicholas A Willis. Nat Rev Mol Cell Biol 2019
Ralph Scully, Arvind Panday, Rajula Elango, Nicholas A Willis. Nat Rev Mol Cell Biol 2019
14
Double-strand break end resection and repair pathway choice.
Lorraine S Symington, Jean Gautier. Annu Rev Genet 2011
Lorraine S Symington, Jean Gautier. Annu Rev Genet 2011
13
DNA Repair Profiling Reveals Nonrandom Outcomes at Cas9-Mediated Breaks.
Megan van Overbeek, Daniel Capurso, Matthew M Carter, Matthew S Thompson, Elizabeth Frias, Carsten Russ, John S Reece-Hoyes, Christopher Nye, Scott Gradia, Bastien Vidal,[...]. Mol Cell 2016
Megan van Overbeek, Daniel Capurso, Matthew M Carter, Matthew S Thompson, Elizabeth Frias, Carsten Russ, John S Reece-Hoyes, Christopher Nye, Scott Gradia, Bastien Vidal,[...]. Mol Cell 2016
13
Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair.
Raphael Ceccaldi, Jessica C Liu, Ravindra Amunugama, Ildiko Hajdu, Benjamin Primack, Mark I R Petalcorin, Kevin W O'Connor, Panagiotis A Konstantinopoulos, Stephen J Elledge, Simon J Boulton,[...]. Nature 2015
Raphael Ceccaldi, Jessica C Liu, Ravindra Amunugama, Ildiko Hajdu, Benjamin Primack, Mark I R Petalcorin, Kevin W O'Connor, Panagiotis A Konstantinopoulos, Stephen J Elledge, Simon J Boulton,[...]. Nature 2015
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The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway.
Michael R Lieber. Annu Rev Biochem 2010
Michael R Lieber. Annu Rev Biochem 2010
13
Predictable and precise template-free CRISPR editing of pathogenic variants.
Max W Shen, Mandana Arbab, Jonathan Y Hsu, Daniel Worstell, Sannie J Culbertson, Olga Krabbe, Christopher A Cassa, David R Liu, David K Gifford, Richard I Sherwood. Nature 2018
Max W Shen, Mandana Arbab, Jonathan Y Hsu, Daniel Worstell, Sannie J Culbertson, Olga Krabbe, Christopher A Cassa, David R Liu, David K Gifford, Richard I Sherwood. Nature 2018
12
Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination.
Pedro A Mateos-Gomez, Fade Gong, Nidhi Nair, Kyle M Miller, Eros Lazzerini-Denchi, Agnel Sfeir. Nature 2015
Pedro A Mateos-Gomez, Fade Gong, Nidhi Nair, Kyle M Miller, Eros Lazzerini-Denchi, Agnel Sfeir. Nature 2015
12
Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system.
Bernd Zetsche, Jonathan S Gootenberg, Omar O Abudayyeh, Ian M Slaymaker, Kira S Makarova, Patrick Essletzbichler, Sara E Volz, Julia Joung, John van der Oost, Aviv Regev,[...]. Cell 2015
Bernd Zetsche, Jonathan S Gootenberg, Omar O Abudayyeh, Ian M Slaymaker, Kira S Makarova, Patrick Essletzbichler, Sara E Volz, Julia Joung, John van der Oost, Aviv Regev,[...]. Cell 2015
12
Multiplex genome engineering using CRISPR/Cas systems.
Le Cong, F Ann Ran, David Cox, Shuailiang Lin, Robert Barretto, Naomi Habib, Patrick D Hsu, Xuebing Wu, Wenyan Jiang, Luciano A Marraffini,[...]. Science 2013
Le Cong, F Ann Ran, David Cox, Shuailiang Lin, Robert Barretto, Naomi Habib, Patrick D Hsu, Xuebing Wu, Wenyan Jiang, Luciano A Marraffini,[...]. Science 2013
12
Target-Specific Precision of CRISPR-Mediated Genome Editing.
Anob M Chakrabarti, Tristan Henser-Brownhill, Josep Monserrat, Anna R Poetsch, Nicholas M Luscombe, Paola Scaffidi. Mol Cell 2019
Anob M Chakrabarti, Tristan Henser-Brownhill, Josep Monserrat, Anna R Poetsch, Nicholas M Luscombe, Paola Scaffidi. Mol Cell 2019
11
Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells.
Van Trung Chu, Timm Weber, Benedikt Wefers, Wolfgang Wurst, Sandrine Sander, Klaus Rajewsky, Ralf Kühn. Nat Biotechnol 2015
Van Trung Chu, Timm Weber, Benedikt Wefers, Wolfgang Wurst, Sandrine Sander, Klaus Rajewsky, Ralf Kühn. Nat Biotechnol 2015
11
Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining.
Takeshi Maruyama, Stephanie K Dougan, Matthias C Truttmann, Angelina M Bilate, Jessica R Ingram, Hidde L Ploegh. Nat Biotechnol 2015
Takeshi Maruyama, Stephanie K Dougan, Matthias C Truttmann, Angelina M Bilate, Jessica R Ingram, Hidde L Ploegh. Nat Biotechnol 2015
11
The shieldin complex mediates 53BP1-dependent DNA repair.
Sylvie M Noordermeer, Salomé Adam, Dheva Setiaputra, Marco Barazas, Stephen J Pettitt, Alexanda K Ling, Michele Olivieri, Alejandro Álvarez-Quilón, Nathalie Moatti, Michal Zimmermann,[...]. Nature 2018
Sylvie M Noordermeer, Salomé Adam, Dheva Setiaputra, Marco Barazas, Stephen J Pettitt, Alexanda K Ling, Michele Olivieri, Alejandro Álvarez-Quilón, Nathalie Moatti, Michal Zimmermann,[...]. Nature 2018
10
Phosphorylated CtIP Functions as a Co-factor of the MRE11-RAD50-NBS1 Endonuclease in DNA End Resection.
Roopesh Anand, Lepakshi Ranjha, Elda Cannavo, Petr Cejka. Mol Cell 2016
Roopesh Anand, Lepakshi Ranjha, Elda Cannavo, Petr Cejka. Mol Cell 2016
10
The control of DNA repair by the cell cycle.
Nicole Hustedt, Daniel Durocher. Nat Cell Biol 2016
Nicole Hustedt, Daniel Durocher. Nat Cell Biol 2016
10
DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.
Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig,[...]. Cell 2018
Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig,[...]. Cell 2018
10
MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings.
Mitch McVey, Sang Eun Lee. Trends Genet 2008
Mitch McVey, Sang Eun Lee. Trends Genet 2008
10
DNA polymerase θ (POLQ), double-strand break repair, and cancer.
Richard D Wood, Sylvie Doublié. DNA Repair (Amst) 2016
Richard D Wood, Sylvie Doublié. DNA Repair (Amst) 2016
10
Predicting the mutations generated by repair of Cas9-induced double-strand breaks.
Felicity Allen, Luca Crepaldi, Clara Alsinet, Alexander J Strong, Vitalii Kleshchevnikov, Pietro De Angeli, Petra Páleníková, Anton Khodak, Vladimir Kiselev, Michael Kosicki,[...]. Nat Biotechnol 2018
Felicity Allen, Luca Crepaldi, Clara Alsinet, Alexander J Strong, Vitalii Kleshchevnikov, Pietro De Angeli, Petra Páleníková, Anton Khodak, Vladimir Kiselev, Michael Kosicki,[...]. Nat Biotechnol 2018
10
CRISPResso2 provides accurate and rapid genome editing sequence analysis.
Kendell Clement, Holly Rees, Matthew C Canver, Jason M Gehrke, Rick Farouni, Jonathan Y Hsu, Mitchel A Cole, David R Liu, J Keith Joung, Daniel E Bauer,[...]. Nat Biotechnol 2019
Kendell Clement, Holly Rees, Matthew C Canver, Jason M Gehrke, Rick Farouni, Jonathan Y Hsu, Mitchel A Cole, David R Liu, J Keith Joung, Daniel E Bauer,[...]. Nat Biotechnol 2019
10
Genome editing with CRISPR-Cas nucleases, base editors, transposases and prime editors.
Andrew V Anzalone, Luke W Koblan, David R Liu. Nat Biotechnol 2020
Andrew V Anzalone, Luke W Koblan, David R Liu. Nat Biotechnol 2020
10
Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks.
David W Wyatt, Wanjuan Feng, Michael P Conlin, Matthew J Yousefzadeh, Steven A Roberts, Piotr Mieczkowski, Richard D Wood, Gaorav P Gupta, Dale A Ramsden. Mol Cell 2016
David W Wyatt, Wanjuan Feng, Michael P Conlin, Matthew J Yousefzadeh, Steven A Roberts, Piotr Mieczkowski, Richard D Wood, Gaorav P Gupta, Dale A Ramsden. Mol Cell 2016
10
Nonhomologous DNA end-joining for repair of DNA double-strand breaks.
Nicholas R Pannunzio, Go Watanabe, Michael R Lieber. J Biol Chem 2018
Nicholas R Pannunzio, Go Watanabe, Michael R Lieber. J Biol Chem 2018
9
53BP1-RIF1-shieldin counteracts DSB resection through CST- and Polα-dependent fill-in.
Zachary Mirman, Francisca Lottersberger, Hiroyuki Takai, Tatsuya Kibe, Yi Gong, Kaori Takai, Alessandro Bianchi, Michal Zimmermann, Daniel Durocher, Titia de Lange. Nature 2018
Zachary Mirman, Francisca Lottersberger, Hiroyuki Takai, Tatsuya Kibe, Yi Gong, Kaori Takai, Alessandro Bianchi, Michal Zimmermann, Daniel Durocher, Titia de Lange. Nature 2018
9
CRISPR-Cas9 genome editing induces megabase-scale chromosomal truncations.
Grégoire Cullot, Julian Boutin, Jérôme Toutain, Florence Prat, Perrine Pennamen, Caroline Rooryck, Martin Teichmann, Emilie Rousseau, Isabelle Lamrissi-Garcia, Véronique Guyonnet-Duperat,[...]. Nat Commun 2019
Grégoire Cullot, Julian Boutin, Jérôme Toutain, Florence Prat, Perrine Pennamen, Caroline Rooryck, Martin Teichmann, Emilie Rousseau, Isabelle Lamrissi-Garcia, Véronique Guyonnet-Duperat,[...]. Nat Commun 2019
9
Repair of DNA double-strand breaks by mammalian alternative end-joining pathways.
Annahita Sallmyr, Alan E Tomkinson. J Biol Chem 2018
Annahita Sallmyr, Alan E Tomkinson. J Biol Chem 2018
9
Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ.
Tatiana Kent, Gurushankar Chandramouly, Shane Michael McDevitt, Ahmet Y Ozdemir, Richard T Pomerantz. Nat Struct Mol Biol 2015
Tatiana Kent, Gurushankar Chandramouly, Shane Michael McDevitt, Ahmet Y Ozdemir, Richard T Pomerantz. Nat Struct Mol Biol 2015
9
Precise and Predictable CRISPR Chromosomal Rearrangements Reveal Principles of Cas9-Mediated Nucleotide Insertion.
Jia Shou, Jinhuan Li, Yingbin Liu, Qiang Wu. Mol Cell 2018
Jia Shou, Jinhuan Li, Yingbin Liu, Qiang Wu. Mol Cell 2018
11
Mechanistic basis for microhomology identification and genome scarring by polymerase theta.
Juan Carvajal-Garcia, Jang-Eun Cho, Pablo Carvajal-Garcia, Wanjuan Feng, Richard D Wood, Jeff Sekelsky, Gaorav P Gupta, Steven A Roberts, Dale A Ramsden. Proc Natl Acad Sci U S A 2020
Juan Carvajal-Garcia, Jang-Eun Cho, Pablo Carvajal-Garcia, Wanjuan Feng, Richard D Wood, Jeff Sekelsky, Gaorav P Gupta, Steven A Roberts, Dale A Ramsden. Proc Natl Acad Sci U S A 2020
19
p53 inhibits CRISPR-Cas9 engineering in human pluripotent stem cells.
Robert J Ihry, Kathleen A Worringer, Max R Salick, Elizabeth Frias, Daniel Ho, Kraig Theriault, Sravya Kommineni, Julie Chen, Marie Sondey, Chaoyang Ye,[...]. Nat Med 2018
Robert J Ihry, Kathleen A Worringer, Max R Salick, Elizabeth Frias, Daniel Ho, Kraig Theriault, Sravya Kommineni, Julie Chen, Marie Sondey, Chaoyang Ye,[...]. Nat Med 2018
8
Regulation of DNA repair pathway choice in S and G2 phases by the NHEJ inhibitor CYREN.
Nausica Arnoult, Adriana Correia, Jiao Ma, Anna Merlo, Sara Garcia-Gomez, Marija Maric, Marco Tognetti, Christopher W Benner, Simon J Boulton, Alan Saghatelian,[...]. Nature 2017
Nausica Arnoult, Adriana Correia, Jiao Ma, Anna Merlo, Sara Garcia-Gomez, Marija Maric, Marco Tognetti, Christopher W Benner, Simon J Boulton, Alan Saghatelian,[...]. Nature 2017
8
Homologous recombination and the repair of DNA double-strand breaks.
William Douglass Wright, Shanaya Shital Shah, Wolf-Dietrich Heyer. J Biol Chem 2018
William Douglass Wright, Shanaya Shital Shah, Wolf-Dietrich Heyer. J Biol Chem 2018
8
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks.
Samuel F Bunting, Elsa Callén, Nancy Wong, Hua-Tang Chen, Federica Polato, Amanda Gunn, Anne Bothmer, Niklas Feldhahn, Oscar Fernandez-Capetillo, Liu Cao,[...]. Cell 2010
Samuel F Bunting, Elsa Callén, Nancy Wong, Hua-Tang Chen, Federica Polato, Amanda Gunn, Anne Bothmer, Niklas Feldhahn, Oscar Fernandez-Capetillo, Liu Cao,[...]. Cell 2010
8
Human CtIP promotes DNA end resection.
Alessandro A Sartori, Claudia Lukas, Julia Coates, Martin Mistrik, Shuang Fu, Jiri Bartek, Richard Baer, Jiri Lukas, Stephen P Jackson. Nature 2007
Alessandro A Sartori, Claudia Lukas, Julia Coates, Martin Mistrik, Shuang Fu, Jiri Bartek, Richard Baer, Jiri Lukas, Stephen P Jackson. Nature 2007
8
Playing the end game: DNA double-strand break repair pathway choice.
J Ross Chapman, Martin R G Taylor, Simon J Boulton. Mol Cell 2012
J Ross Chapman, Martin R G Taylor, Simon J Boulton. Mol Cell 2012
8
The DNA damage response: making it safe to play with knives.
Alberto Ciccia, Stephen J Elledge. Mol Cell 2010
Alberto Ciccia, Stephen J Elledge. Mol Cell 2010
8
Mechanism and regulation of DNA end resection in eukaryotes.
Lorraine S Symington. Crit Rev Biochem Mol Biol 2016
Lorraine S Symington. Crit Rev Biochem Mol Biol 2016
8
CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle.
Maximina H Yun, Kevin Hiom. Nature 2009
Maximina H Yun, Kevin Hiom. Nature 2009
8
Large dataset enables prediction of repair after CRISPR-Cas9 editing in primary T cells.
Ryan T Leenay, Amirali Aghazadeh, Joseph Hiatt, David Tse, Theodore L Roth, Ryan Apathy, Eric Shifrut, Judd F Hultquist, Nevan Krogan, Zhenqin Wu,[...]. Nat Biotechnol 2019
Ryan T Leenay, Amirali Aghazadeh, Joseph Hiatt, David Tse, Theodore L Roth, Ryan Apathy, Eric Shifrut, Judd F Hultquist, Nevan Krogan, Zhenqin Wu,[...]. Nat Biotechnol 2019
18
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.