Shingo Kajimura, Bruce M Spiegelman, Patrick Seale. Cell Metab 2015
Times Cited: 530
Times Cited: 530
Times Cited
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Similarity
Brown and beige fat: development, function and therapeutic potential.
Matthew Harms, Patrick Seale. Nat Med 2013
Matthew Harms, Patrick Seale. Nat Med 2013
31
Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human.
Jun Wu, Pontus Boström, Lauren M Sparks, Li Ye, Jang Hyun Choi, An-Hoa Giang, Melin Khandekar, Kirsi A Virtanen, Pirjo Nuutila, Gert Schaart,[...]. Cell 2012
Jun Wu, Pontus Boström, Lauren M Sparks, Li Ye, Jang Hyun Choi, An-Hoa Giang, Melin Khandekar, Kirsi A Virtanen, Pirjo Nuutila, Gert Schaart,[...]. Cell 2012
30
Identification and importance of brown adipose tissue in adult humans.
Aaron M Cypess, Sanaz Lehman, Gethin Williams, Ilan Tal, Dean Rodman, Allison B Goldfine, Frank C Kuo, Edwin L Palmer, Yu-Hua Tseng, Alessandro Doria,[...]. N Engl J Med 2009
Aaron M Cypess, Sanaz Lehman, Gethin Williams, Ilan Tal, Dean Rodman, Allison B Goldfine, Frank C Kuo, Edwin L Palmer, Yu-Hua Tseng, Alessandro Doria,[...]. N Engl J Med 2009
24
Brown adipose tissue: function and physiological significance.
Barbara Cannon, Jan Nedergaard. Physiol Rev 2004
Barbara Cannon, Jan Nedergaard. Physiol Rev 2004
24
Cold-activated brown adipose tissue in healthy men.
Wouter D van Marken Lichtenbelt, Joost W Vanhommerig, Nanda M Smulders, Jamie M A F L Drossaerts, Gerrit J Kemerink, Nicole D Bouvy, Patrick Schrauwen, G J Jaap Teule. N Engl J Med 2009
Wouter D van Marken Lichtenbelt, Joost W Vanhommerig, Nanda M Smulders, Jamie M A F L Drossaerts, Gerrit J Kemerink, Nicole D Bouvy, Patrick Schrauwen, G J Jaap Teule. N Engl J Med 2009
22
Brown and beige fat in humans: thermogenic adipocytes that control energy and glucose homeostasis.
Labros Sidossis, Shingo Kajimura. J Clin Invest 2015
Labros Sidossis, Shingo Kajimura. J Clin Invest 2015
17
Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice.
Patrick Seale, Heather M Conroe, Jennifer Estall, Shingo Kajimura, Andrea Frontini, Jeff Ishibashi, Paul Cohen, Saverio Cinti, Bruce M Spiegelman. J Clin Invest 2011
Patrick Seale, Heather M Conroe, Jennifer Estall, Shingo Kajimura, Andrea Frontini, Jeff Ishibashi, Paul Cohen, Saverio Cinti, Bruce M Spiegelman. J Clin Invest 2011
17
Tracking adipogenesis during white adipose tissue development, expansion and regeneration.
Qiong A Wang, Caroline Tao, Rana K Gupta, Philipp E Scherer. Nat Med 2013
Qiong A Wang, Caroline Tao, Rana K Gupta, Philipp E Scherer. Nat Med 2013
15
Functional brown adipose tissue in healthy adults.
Kirsi A Virtanen, Martin E Lidell, Janne Orava, Mikael Heglind, Rickard Westergren, Tarja Niemi, Markku Taittonen, Jukka Laine, Nina-Johanna Savisto, Sven Enerbäck,[...]. N Engl J Med 2009
Kirsi A Virtanen, Martin E Lidell, Janne Orava, Mikael Heglind, Rickard Westergren, Tarja Niemi, Markku Taittonen, Jukka Laine, Nina-Johanna Savisto, Sven Enerbäck,[...]. N Engl J Med 2009
15
Recruited brown adipose tissue as an antiobesity agent in humans.
Takeshi Yoneshiro, Sayuri Aita, Mami Matsushita, Takashi Kayahara, Toshimitsu Kameya, Yuko Kawai, Toshihiko Iwanaga, Masayuki Saito. J Clin Invest 2013
Takeshi Yoneshiro, Sayuri Aita, Mami Matsushita, Takashi Kayahara, Toshimitsu Kameya, Yuko Kawai, Toshihiko Iwanaga, Masayuki Saito. J Clin Invest 2013
15
PPARγ agonists induce a white-to-brown fat conversion through stabilization of PRDM16 protein.
Haruya Ohno, Kosaku Shinoda, Bruce M Spiegelman, Shingo Kajimura. Cell Metab 2012
Haruya Ohno, Kosaku Shinoda, Bruce M Spiegelman, Shingo Kajimura. Cell Metab 2012
13
13
Adipose tissue browning and metabolic health.
Alexander Bartelt, Joerg Heeren. Nat Rev Endocrinol 2014
Alexander Bartelt, Joerg Heeren. Nat Rev Endocrinol 2014
13
Metabolic adaptation and maladaptation in adipose tissue.
Edward T Chouchani, Shingo Kajimura. Nat Metab 2019
Edward T Chouchani, Shingo Kajimura. Nat Metab 2019
11
FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis.
Ffolliott M Fisher, Sandra Kleiner, Nicholas Douris, Elliott C Fox, Rina J Mepani, Francisco Verdeguer, Jun Wu, Alexei Kharitonenkov, Jeffrey S Flier, Eleftheria Maratos-Flier,[...]. Genes Dev 2012
Ffolliott M Fisher, Sandra Kleiner, Nicholas Douris, Elliott C Fox, Rina J Mepani, Francisco Verdeguer, Jun Wu, Alexei Kharitonenkov, Jeffrey S Flier, Eleftheria Maratos-Flier,[...]. Genes Dev 2012
11
UCP1-independent signaling involving SERCA2b-mediated calcium cycling regulates beige fat thermogenesis and systemic glucose homeostasis.
Kenji Ikeda, Qianqian Kang, Takeshi Yoneshiro, Joao Paulo Camporez, Hiroko Maki, Mayu Homma, Kosaku Shinoda, Yong Chen, Xiaodan Lu, Pema Maretich,[...]. Nat Med 2017
Kenji Ikeda, Qianqian Kang, Takeshi Yoneshiro, Joao Paulo Camporez, Hiroko Maki, Mayu Homma, Kosaku Shinoda, Yong Chen, Xiaodan Lu, Pema Maretich,[...]. Nat Med 2017
11
Activation of human brown adipose tissue by a β3-adrenergic receptor agonist.
Aaron M Cypess, Lauren S Weiner, Carla Roberts-Toler, Elisa Franquet Elía, Skyler H Kessler, Peter A Kahn, Jeffrey English, Kelly Chatman, Sunia A Trauger, Alessandro Doria,[...]. Cell Metab 2015
Aaron M Cypess, Lauren S Weiner, Carla Roberts-Toler, Elisa Franquet Elía, Skyler H Kessler, Peter A Kahn, Jeffrey English, Kelly Chatman, Sunia A Trauger, Alessandro Doria,[...]. Cell Metab 2015
11
Bi-directional interconversion of brite and white adipocytes.
Matthias Rosenwald, Aliki Perdikari, Thomas Rülicke, Christian Wolfrum. Nat Cell Biol 2013
Matthias Rosenwald, Aliki Perdikari, Thomas Rülicke, Christian Wolfrum. Nat Cell Biol 2013
11
Beige Adipocyte Maintenance Is Regulated by Autophagy-Induced Mitochondrial Clearance.
Svetlana Altshuler-Keylin, Kosaku Shinoda, Yutaka Hasegawa, Kenji Ikeda, Haemin Hong, Qianqian Kang, Yangyu Yang, Rushika M Perera, Jayanta Debnath, Shingo Kajimura. Cell Metab 2016
Svetlana Altshuler-Keylin, Kosaku Shinoda, Yutaka Hasegawa, Kenji Ikeda, Haemin Hong, Qianqian Kang, Yangyu Yang, Rushika M Perera, Jayanta Debnath, Shingo Kajimura. Cell Metab 2016
11
Adaptive thermogenesis in adipocytes: is beige the new brown?
Jun Wu, Paul Cohen, Bruce M Spiegelman. Genes Dev 2013
Jun Wu, Paul Cohen, Bruce M Spiegelman. Genes Dev 2013
11
Chronic peroxisome proliferator-activated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic brown adipocytes.
Natasa Petrovic, Tomas B Walden, Irina G Shabalina, James A Timmons, Barbara Cannon, Jan Nedergaard. J Biol Chem 2010
Natasa Petrovic, Tomas B Walden, Irina G Shabalina, James A Timmons, Barbara Cannon, Jan Nedergaard. J Biol Chem 2010
11
PRDM16 controls a brown fat/skeletal muscle switch.
Patrick Seale, Bryan Bjork, Wenli Yang, Shingo Kajimura, Sherry Chin, Shihuan Kuang, Anthony Scimè, Srikripa Devarakonda, Heather M Conroe, Hediye Erdjument-Bromage,[...]. Nature 2008
Patrick Seale, Bryan Bjork, Wenli Yang, Shingo Kajimura, Sherry Chin, Shihuan Kuang, Anthony Scimè, Srikripa Devarakonda, Heather M Conroe, Hediye Erdjument-Bromage,[...]. Nature 2008
10
Adipocytes as regulators of energy balance and glucose homeostasis.
Evan D Rosen, Bruce M Spiegelman. Nature 2006
Evan D Rosen, Bruce M Spiegelman. Nature 2006
10
High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposity.
Masayuki Saito, Yuko Okamatsu-Ogura, Mami Matsushita, Kumiko Watanabe, Takeshi Yoneshiro, Junko Nio-Kobayashi, Toshihiko Iwanaga, Masao Miyagawa, Toshimitsu Kameya, Kunihiro Nakada,[...]. Diabetes 2009
Masayuki Saito, Yuko Okamatsu-Ogura, Mami Matsushita, Kumiko Watanabe, Takeshi Yoneshiro, Junko Nio-Kobayashi, Toshihiko Iwanaga, Masao Miyagawa, Toshimitsu Kameya, Kunihiro Nakada,[...]. Diabetes 2009
10
New Advances in Adaptive Thermogenesis: UCP1 and Beyond.
Edward T Chouchani, Lawrence Kazak, Bruce M Spiegelman. Cell Metab 2019
Edward T Chouchani, Lawrence Kazak, Bruce M Spiegelman. Cell Metab 2019
10
Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation.
Marc Uldry, Wenli Yang, Julie St-Pierre, Jiandie Lin, Patrick Seale, Bruce M Spiegelman. Cell Metab 2006
Marc Uldry, Wenli Yang, Julie St-Pierre, Jiandie Lin, Patrick Seale, Bruce M Spiegelman. Cell Metab 2006
9
Transcriptional control of brown fat determination by PRDM16.
Patrick Seale, Shingo Kajimura, Wenli Yang, Sherry Chin, Lindsay M Rohas, Marc Uldry, Geneviève Tavernier, Dominique Langin, Bruce M Spiegelman. Cell Metab 2007
Patrick Seale, Shingo Kajimura, Wenli Yang, Sherry Chin, Lindsay M Rohas, Marc Uldry, Geneviève Tavernier, Dominique Langin, Bruce M Spiegelman. Cell Metab 2007
9
In vivo identification of bipotential adipocyte progenitors recruited by β3-adrenoceptor activation and high-fat feeding.
Yun-Hee Lee, Anelia P Petkova, Emilio P Mottillo, James G Granneman. Cell Metab 2012
Yun-Hee Lee, Anelia P Petkova, Emilio P Mottillo, James G Granneman. Cell Metab 2012
9
The Common and Distinct Features of Brown and Beige Adipocytes.
Kenji Ikeda, Pema Maretich, Shingo Kajimura. Trends Endocrinol Metab 2018
Kenji Ikeda, Pema Maretich, Shingo Kajimura. Trends Endocrinol Metab 2018
9
Fibrosis and adipose tissue dysfunction.
Kai Sun, Joan Tordjman, Karine Clément, Philipp E Scherer. Cell Metab 2013
Kai Sun, Joan Tordjman, Karine Clément, Philipp E Scherer. Cell Metab 2013
9
Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch.
Paul Cohen, Julia D Levy, Yingying Zhang, Andrea Frontini, Dmitriy P Kolodin, Katrin J Svensson, James C Lo, Xing Zeng, Li Ye, Melin J Khandekar,[...]. Cell 2014
Paul Cohen, Julia D Levy, Yingying Zhang, Andrea Frontini, Dmitriy P Kolodin, Katrin J Svensson, James C Lo, Xing Zeng, Li Ye, Melin J Khandekar,[...]. Cell 2014
9
Human BAT possesses molecular signatures that resemble beige/brite cells.
Louis Z Sharp, Kosaku Shinoda, Haruya Ohno, David W Scheel, Emi Tomoda, Lauren Ruiz, Houchun Hu, Larry Wang, Zdena Pavlova, Vicente Gilsanz,[...]. PLoS One 2012
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9
Brown adipose tissue activity controls triglyceride clearance.
Alexander Bartelt, Oliver T Bruns, Rudolph Reimer, Heinz Hohenberg, Harald Ittrich, Kersten Peldschus, Michael G Kaul, Ulrich I Tromsdorf, Horst Weller, Christian Waurisch,[...]. Nat Med 2011
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8
Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Pparγ.
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The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation.
G Barbatelli, I Murano, L Madsen, Q Hao, M Jimenez, K Kristiansen, J P Giacobino, R De Matteis, S Cinti. Am J Physiol Endocrinol Metab 2010
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Targeting adipose tissue in the treatment of obesity-associated diabetes.
Christine M Kusminski, Perry E Bickel, Philipp E Scherer. Nat Rev Drug Discov 2016
Christine M Kusminski, Perry E Bickel, Philipp E Scherer. Nat Rev Drug Discov 2016
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Brown adipose tissue in the parametrial fat pad of the mouse.
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Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat.
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Multilocular fat cells in WAT of CL-316243-treated rats derive directly from white adipocytes.
J Himms-Hagen, A Melnyk, M C Zingaretti, E Ceresi, G Barbatelli, S Cinti. Am J Physiol Cell Physiol 2000
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Human 'brite/beige' adipocytes develop from capillary networks, and their implantation improves metabolic homeostasis in mice.
So Yun Min, Jamie Kady, Minwoo Nam, Raziel Rojas-Rodriguez, Aaron Berkenwald, Jong Hun Kim, Hye-Lim Noh, Jason K Kim, Marcus P Cooper, Timothy Fitzgibbons,[...]. Nat Med 2016
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Mechanism of fatty-acid-dependent UCP1 uncoupling in brown fat mitochondria.
Andriy Fedorenko, Polina V Lishko, Yuriy Kirichok. Cell 2012
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A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis.
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A creatine-driven substrate cycle enhances energy expenditure and thermogenesis in beige fat.
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Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans.
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UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality.
Helena M Feldmann, Valeria Golozoubova, Barbara Cannon, Jan Nedergaard. Cell Metab 2009
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Dynamics of fat cell turnover in humans.
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Mapping of human brown adipose tissue in lean and obese young men.
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A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis.
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7
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