Hei-man Chow, Karl Herrup. Nat Rev Neurosci 2015
Times Cited: 100
Times Cited: 100
Times Cited
Times Co-cited
Similarity
The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
28
DNA damage and its links to neurodegeneration.
Ram Madabhushi, Ling Pan, Li-Huei Tsai. Neuron 2014
Ram Madabhushi, Ling Pan, Li-Huei Tsai. Neuron 2014
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Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β.
Elsa Suberbielle, Pascal E Sanchez, Alexxai V Kravitz, Xin Wang, Kaitlyn Ho, Kirsten Eilertson, Nino Devidze, Anatol C Kreitzer, Lennart Mucke. Nat Neurosci 2013
Elsa Suberbielle, Pascal E Sanchez, Alexxai V Kravitz, Xin Wang, Kaitlyn Ho, Kirsten Eilertson, Nino Devidze, Anatol C Kreitzer, Lennart Mucke. Nat Neurosci 2013
21
17
Activity-Induced DNA Breaks Govern the Expression of Neuronal Early-Response Genes.
Ram Madabhushi, Fan Gao, Andreas R Pfenning, Ling Pan, Satoko Yamakawa, Jinsoo Seo, Richard Rueda, Trongha X Phan, Hidekuni Yamakawa, Ping-Chieh Pao,[...]. Cell 2015
Ram Madabhushi, Fan Gao, Andreas R Pfenning, Ling Pan, Satoko Yamakawa, Jinsoo Seo, Richard Rueda, Trongha X Phan, Hidekuni Yamakawa, Ping-Chieh Pao,[...]. Cell 2015
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Gene regulation and DNA damage in the ageing human brain.
Tao Lu, Ying Pan, Shyan-Yuan Kao, Cheng Li, Isaac Kohane, Jennifer Chan, Bruce A Yankner. Nature 2004
Tao Lu, Ying Pan, Shyan-Yuan Kao, Cheng Li, Isaac Kohane, Jennifer Chan, Bruce A Yankner. Nature 2004
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NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair.
Evandro Fei Fang, Henok Kassahun, Deborah L Croteau, Morten Scheibye-Knudsen, Krisztina Marosi, Huiming Lu, Raghavendra A Shamanna, Sumana Kalyanasundaram, Ravi Chand Bollineni, Mark A Wilson,[...]. Cell Metab 2016
Evandro Fei Fang, Henok Kassahun, Deborah L Croteau, Morten Scheibye-Knudsen, Krisztina Marosi, Huiming Lu, Raghavendra A Shamanna, Sumana Kalyanasundaram, Ravi Chand Bollineni, Mark A Wilson,[...]. Cell Metab 2016
12
Aging and neurodegeneration are associated with increased mutations in single human neurons.
Michael A Lodato, Rachel E Rodin, Craig L Bohrson, Michael E Coulter, Alison R Barton, Minseok Kwon, Maxwell A Sherman, Carl M Vitzthum, Lovelace J Luquette, Chandri N Yandava,[...]. Science 2018
Michael A Lodato, Rachel E Rodin, Craig L Bohrson, Michael E Coulter, Alison R Barton, Minseok Kwon, Maxwell A Sherman, Carl M Vitzthum, Lovelace J Luquette, Chandri N Yandava,[...]. Science 2018
12
Defective mitophagy in XPA via PARP-1 hyperactivation and NAD(+)/SIRT1 reduction.
Evandro Fei Fang, Morten Scheibye-Knudsen, Lear E Brace, Henok Kassahun, Tanima SenGupta, Hilde Nilsen, James R Mitchell, Deborah L Croteau, Vilhelm A Bohr. Cell 2014
Evandro Fei Fang, Morten Scheibye-Knudsen, Lear E Brace, Henok Kassahun, Tanima SenGupta, Hilde Nilsen, James R Mitchell, Deborah L Croteau, Vilhelm A Bohr. Cell 2014
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Mosaic copy number variation in human neurons.
Michael J McConnell, Michael R Lindberg, Kristen J Brennand, Julia C Piper, Thierry Voet, Chris Cowing-Zitron, Svetlana Shumilina, Roger S Lasken, Joris R Vermeesch, Ira M Hall,[...]. Science 2013
Michael J McConnell, Michael R Lindberg, Kristen J Brennand, Julia C Piper, Thierry Voet, Chris Cowing-Zitron, Svetlana Shumilina, Roger S Lasken, Joris R Vermeesch, Ira M Hall,[...]. Science 2013
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Genome instability in Alzheimer disease.
Yujun Hou, Hyundong Song, Deborah L Croteau, Mansour Akbari, Vilhelm A Bohr. Mech Ageing Dev 2017
Yujun Hou, Hyundong Song, Deborah L Croteau, Mansour Akbari, Vilhelm A Bohr. Mech Ageing Dev 2017
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Inefficient DNA Repair Is an Aging-Related Modifier of Parkinson's Disease.
Sara Sepe, Chiara Milanese, Sylvia Gabriels, Kasper W J Derks, Cesar Payan-Gomez, Wilfred F J van IJcken, Yvonne M A Rijksen, Alex L Nigg, Sandra Moreno, Silvia Cerri,[...]. Cell Rep 2016
Sara Sepe, Chiara Milanese, Sylvia Gabriels, Kasper W J Derks, Cesar Payan-Gomez, Wilfred F J van IJcken, Yvonne M A Rijksen, Alex L Nigg, Sandra Moreno, Silvia Cerri,[...]. Cell Rep 2016
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Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks.
Olga A Sedelnikova, Izumi Horikawa, Drazen B Zimonjic, Nicholas C Popescu, William M Bonner, J Carl Barrett. Nat Cell Biol 2004
Olga A Sedelnikova, Izumi Horikawa, Drazen B Zimonjic, Nicholas C Popescu, William M Bonner, J Carl Barrett. Nat Cell Biol 2004
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Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition.
Alysson R Muotri, Vi T Chu, Maria C N Marchetto, Wei Deng, John V Moran, Fred H Gage. Nature 2005
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Nuclear DNA damage signalling to mitochondria in ageing.
Evandro Fei Fang, Morten Scheibye-Knudsen, Katrin F Chua, Mark P Mattson, Deborah L Croteau, Vilhelm A Bohr. Nat Rev Mol Cell Biol 2016
Evandro Fei Fang, Morten Scheibye-Knudsen, Katrin F Chua, Mark P Mattson, Deborah L Croteau, Vilhelm A Bohr. Nat Rev Mol Cell Biol 2016
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Mitophagy and Alzheimer's Disease: Cellular and Molecular Mechanisms.
Jesse S Kerr, Bryan A Adriaanse, Nigel H Greig, Mark P Mattson, M Zameel Cader, Vilhelm A Bohr, Evandro F Fang. Trends Neurosci 2017
Jesse S Kerr, Bryan A Adriaanse, Nigel H Greig, Mark P Mattson, M Zameel Cader, Vilhelm A Bohr, Evandro F Fang. Trends Neurosci 2017
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Hallmarks of Brain Aging: Adaptive and Pathological Modification by Metabolic States.
Mark P Mattson, Thiruma V Arumugam. Cell Metab 2018
Mark P Mattson, Thiruma V Arumugam. Cell Metab 2018
9
Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response.
Diana Jurk, Chunfang Wang, Satomi Miwa, Mandy Maddick, Viktor Korolchuk, Avgi Tsolou, Efstathios S Gonos, Christopher Thrasivoulou, M Jill Saffrey, Kerry Cameron,[...]. Aging Cell 2012
Diana Jurk, Chunfang Wang, Satomi Miwa, Mandy Maddick, Viktor Korolchuk, Avgi Tsolou, Efstathios S Gonos, Christopher Thrasivoulou, M Jill Saffrey, Kerry Cameron,[...]. Aging Cell 2012
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Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders.
Darren J Baker, Tobias Wijshake, Tamar Tchkonia, Nathan K LeBrasseur, Bennett G Childs, Bart van de Sluis, James L Kirkland, Jan M van Deursen. Nature 2011
Darren J Baker, Tobias Wijshake, Tamar Tchkonia, Nathan K LeBrasseur, Bennett G Childs, Bart van de Sluis, James L Kirkland, Jan M van Deursen. Nature 2011
8
Defective DNA base excision repair in brain from individuals with Alzheimer's disease and amnestic mild cognitive impairment.
Lior Weissman, Dong-Gyu Jo, Martin M Sørensen, Nadja C de Souza-Pinto, William R Markesbery, Mark P Mattson, Vilhelm A Bohr. Nucleic Acids Res 2007
Lior Weissman, Dong-Gyu Jo, Martin M Sørensen, Nadja C de Souza-Pinto, William R Markesbery, Mark P Mattson, Vilhelm A Bohr. Nucleic Acids Res 2007
8
DNA polymerase β deficiency leads to neurodegeneration and exacerbates Alzheimer disease phenotypes.
Peter Sykora, Magdalena Misiak, Yue Wang, Somnath Ghosh, Giovana S Leandro, Dong Liu, Jane Tian, Beverly A Baptiste, Wei-Na Cong, Boris M Brenerman,[...]. Nucleic Acids Res 2015
Peter Sykora, Magdalena Misiak, Yue Wang, Somnath Ghosh, Giovana S Leandro, Dong Liu, Jane Tian, Beverly A Baptiste, Wei-Na Cong, Boris M Brenerman,[...]. Nucleic Acids Res 2015
11
Cell cycle regulation in the postmitotic neuron: oxymoron or new biology?
Karl Herrup, Yan Yang. Nat Rev Neurosci 2007
Karl Herrup, Yan Yang. Nat Rev Neurosci 2007
8
NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice.
Hongbo Zhang, Dongryeol Ryu, Yibo Wu, Karim Gariani, Xu Wang, Peiling Luan, Davide D'Amico, Eduardo R Ropelle, Matthias P Lutolf, Ruedi Aebersold,[...]. Science 2016
Hongbo Zhang, Dongryeol Ryu, Yibo Wu, Karim Gariani, Xu Wang, Peiling Luan, Davide D'Amico, Eduardo R Ropelle, Matthias P Lutolf, Ruedi Aebersold,[...]. Science 2016
8
NAD+ supplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency.
Yujun Hou, Sofie Lautrup, Stephanie Cordonnier, Yue Wang, Deborah L Croteau, Eduardo Zavala, Yongqing Zhang, Kanako Moritoh, Jennifer F O'Connell, Beverly A Baptiste,[...]. Proc Natl Acad Sci U S A 2018
Yujun Hou, Sofie Lautrup, Stephanie Cordonnier, Yue Wang, Deborah L Croteau, Eduardo Zavala, Yongqing Zhang, Kanako Moritoh, Jennifer F O'Connell, Beverly A Baptiste,[...]. Proc Natl Acad Sci U S A 2018
8
Early neuronal accumulation of DNA double strand breaks in Alzheimer's disease.
Niraj M Shanbhag, Mark D Evans, Wenjie Mao, Alissa L Nana, William W Seeley, Anthony Adame, Robert A Rissman, Eliezer Masliah, Lennart Mucke. Acta Neuropathol Commun 2019
Niraj M Shanbhag, Mark D Evans, Wenjie Mao, Alissa L Nana, William W Seeley, Anthony Adame, Robert A Rissman, Eliezer Masliah, Lennart Mucke. Acta Neuropathol Commun 2019
13
The DNA-damage response in human biology and disease.
Stephen P Jackson, Jiri Bartek. Nature 2009
Stephen P Jackson, Jiri Bartek. Nature 2009
7
Somatic mutation in single human neurons tracks developmental and transcriptional history.
Michael A Lodato, Mollie B Woodworth, Semin Lee, Gilad D Evrony, Bhaven K Mehta, Amir Karger, Soohyun Lee, Thomas W Chittenden, Alissa M D'Gama, Xuyu Cai,[...]. Science 2015
Michael A Lodato, Mollie B Woodworth, Semin Lee, Gilad D Evrony, Bhaven K Mehta, Amir Karger, Soohyun Lee, Thomas W Chittenden, Alissa M D'Gama, Xuyu Cai,[...]. Science 2015
7
DNA repair factor BRCA1 depletion occurs in Alzheimer brains and impairs cognitive function in mice.
Elsa Suberbielle, Biljana Djukic, Mark Evans, Daniel H Kim, Praveen Taneja, Xin Wang, Mariel Finucane, Joseph Knox, Kaitlyn Ho, Nino Devidze,[...]. Nat Commun 2015
Elsa Suberbielle, Biljana Djukic, Mark Evans, Daniel H Kim, Praveen Taneja, Xin Wang, Mariel Finucane, Joseph Knox, Kaitlyn Ho, Nino Devidze,[...]. Nat Commun 2015
7
Somatic retrotransposition alters the genetic landscape of the human brain.
J Kenneth Baillie, Mark W Barnett, Kyle R Upton, Daniel J Gerhardt, Todd A Richmond, Fioravante De Sapio, Paul M Brennan, Patrizia Rizzu, Sarah Smith, Mark Fell,[...]. Nature 2011
J Kenneth Baillie, Mark W Barnett, Kyle R Upton, Daniel J Gerhardt, Todd A Richmond, Fioravante De Sapio, Paul M Brennan, Patrizia Rizzu, Sarah Smith, Mark Fell,[...]. Nature 2011
7
Single-neuron sequencing analysis of L1 retrotransposition and somatic mutation in the human brain.
Gilad D Evrony, Xuyu Cai, Eunjung Lee, L Benjamin Hills, Princess C Elhosary, Hillel S Lehmann, J J Parker, Kutay D Atabay, Edward C Gilmore, Annapurna Poduri,[...]. Cell 2012
Gilad D Evrony, Xuyu Cai, Eunjung Lee, L Benjamin Hills, Princess C Elhosary, Hillel S Lehmann, J J Parker, Kutay D Atabay, Edward C Gilmore, Annapurna Poduri,[...]. Cell 2012
7
Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models.
Bing Gong, Yong Pan, Prashant Vempati, Wei Zhao, Lindsay Knable, Lap Ho, Jun Wang, Magdalena Sastre, Kenjiro Ono, Anthony A Sauve,[...]. Neurobiol Aging 2013
Bing Gong, Yong Pan, Prashant Vempati, Wei Zhao, Lindsay Knable, Lap Ho, Jun Wang, Magdalena Sastre, Kenjiro Ono, Anthony A Sauve,[...]. Neurobiol Aging 2013
7
Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network.
Michael J McConnell, John V Moran, Alexej Abyzov, Schahram Akbarian, Taejeong Bae, Isidro Cortes-Ciriano, Jennifer A Erwin, Liana Fasching, Diane A Flasch, Donald Freed,[...]. Science 2017
Michael J McConnell, John V Moran, Alexej Abyzov, Schahram Akbarian, Taejeong Bae, Isidro Cortes-Ciriano, Jennifer A Erwin, Liana Fasching, Diane A Flasch, Donald Freed,[...]. Science 2017
7
Genomic mosaicism with increased amyloid precursor protein (APP) gene copy number in single neurons from sporadic Alzheimer's disease brains.
Diane M Bushman, Gwendolyn E Kaeser, Benjamin Siddoway, Jurgen W Westra, Richard R Rivera, Stevens K Rehen, Yun C Yung, Jerold Chun. Elife 2015
Diane M Bushman, Gwendolyn E Kaeser, Benjamin Siddoway, Jurgen W Westra, Richard R Rivera, Stevens K Rehen, Yun C Yung, Jerold Chun. Elife 2015
8
Engineered LINE-1 retrotransposition in nondividing human neurons.
Angela Macia, Thomas J Widmann, Sara R Heras, Veronica Ayllon, Laura Sanchez, Meriem Benkaddour-Boumzaouad, Martin Muñoz-Lopez, Alejandro Rubio, Suyapa Amador-Cubero, Eva Blanco-Jimenez,[...]. Genome Res 2017
Angela Macia, Thomas J Widmann, Sara R Heras, Veronica Ayllon, Laura Sanchez, Meriem Benkaddour-Boumzaouad, Martin Muñoz-Lopez, Alejandro Rubio, Suyapa Amador-Cubero, Eva Blanco-Jimenez,[...]. Genome Res 2017
9
The DNA Damage Response in Neurons: Die by Apoptosis or Survive in a Senescence-Like State?
Edward Fielder, Thomas von Zglinicki, Diana Jurk. J Alzheimers Dis 2017
Edward Fielder, Thomas von Zglinicki, Diana Jurk. J Alzheimers Dis 2017
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Ageing as a risk factor for neurodegenerative disease.
Yujun Hou, Xiuli Dan, Mansi Babbar, Yong Wei, Steen G Hasselbalch, Deborah L Croteau, Vilhelm A Bohr. Nat Rev Neurol 2019
Yujun Hou, Xiuli Dan, Mansi Babbar, Yong Wei, Steen G Hasselbalch, Deborah L Croteau, Vilhelm A Bohr. Nat Rev Neurol 2019
7
Defective DNA repair and neurodegenerative disease.
Ulrich Rass, Ivan Ahel, Stephen C West. Cell 2007
Ulrich Rass, Ivan Ahel, Stephen C West. Cell 2007
6
A high-fat diet and NAD(+) activate Sirt1 to rescue premature aging in cockayne syndrome.
Morten Scheibye-Knudsen, Sarah J Mitchell, Evandro F Fang, Teruaki Iyama, Theresa Ward, James Wang, Christopher A Dunn, Nagendra Singh, Sebastian Veith, Md Mahdi Hasan-Olive,[...]. Cell Metab 2014
Morten Scheibye-Knudsen, Sarah J Mitchell, Evandro F Fang, Teruaki Iyama, Theresa Ward, James Wang, Christopher A Dunn, Nagendra Singh, Sebastian Veith, Md Mahdi Hasan-Olive,[...]. Cell Metab 2014
6
Ataxia telangiectasia mutated activation by transcription- and topoisomerase I-induced DNA double-strand breaks.
Olivier Sordet, Christophe E Redon, Josée Guirouilh-Barbat, Susan Smith, Stéphanie Solier, Céline Douarre, Chiara Conti, Asako J Nakamura, Benu B Das, Estelle Nicolas,[...]. EMBO Rep 2009
Olivier Sordet, Christophe E Redon, Josée Guirouilh-Barbat, Susan Smith, Stéphanie Solier, Céline Douarre, Chiara Conti, Asako J Nakamura, Benu B Das, Estelle Nicolas,[...]. EMBO Rep 2009
6
Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes.
Sachin Katyal, Youngsoo Lee, Karin C Nitiss, Susanna M Downing, Yang Li, Mikio Shimada, Jingfeng Zhao, Helen R Russell, John H J Petrini, John L Nitiss,[...]. Nat Neurosci 2014
Sachin Katyal, Youngsoo Lee, Karin C Nitiss, Susanna M Downing, Yang Li, Mikio Shimada, Jingfeng Zhao, Helen R Russell, John H J Petrini, John L Nitiss,[...]. Nat Neurosci 2014
6
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics.
John Hardy, Dennis J Selkoe. Science 2002
John Hardy, Dennis J Selkoe. Science 2002
6
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases.
Michael T Lin, M Flint Beal. Nature 2006
Michael T Lin, M Flint Beal. Nature 2006
6
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2.
Michael I Love, Wolfgang Huber, Simon Anders. Genome Biol 2014
Michael I Love, Wolfgang Huber, Simon Anders. Genome Biol 2014
6
Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing.
Anna V Molofsky, Shalom G Slutsky, Nancy M Joseph, Shenghui He, Ricardo Pardal, Janakiraman Krishnamurthy, Norman E Sharpless, Sean J Morrison. Nature 2006
Anna V Molofsky, Shalom G Slutsky, Nancy M Joseph, Shenghui He, Ricardo Pardal, Janakiraman Krishnamurthy, Norman E Sharpless, Sean J Morrison. Nature 2006
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Endogenous DNA Damage as a Source of Genomic Instability in Cancer.
Anthony Tubbs, André Nussenzweig. Cell 2017
Anthony Tubbs, André Nussenzweig. Cell 2017
6
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.