Andrey Korshunov, David Capper, David Reuss, Daniel Schrimpf, Marina Ryzhova, Volker Hovestadt, Dominik Sturm, Jochen Meyer, Chris Jones, Olga Zheludkova, Ella Kumirova, Andrey Golanov, Marcel Kool, Ulrich Schüller, Michel Mittelbronn, Martin Hasselblatt, Jens Schittenhelm, Guido Reifenberger, Christel Herold-Mende, Peter Lichter, Andreas von Deimling, Stefan M Pfister, David T W Jones. Acta Neuropathol 2016
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Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.
Dominik Sturm, Hendrik Witt, Volker Hovestadt, Dong-Anh Khuong-Quang, David T W Jones, Carolin Konermann, Elke Pfaff, Martje Tönjes, Martin Sill, Sebastian Bender,[...]. Cancer Cell 2012
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Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma.
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Jeremy Schwartzentruber, Andrey Korshunov, Xiao-Yang Liu, David T W Jones, Elke Pfaff, Karine Jacob, Dominik Sturm, Adam M Fontebasso, Dong-Anh Khuong Quang, Martje Tönjes,[...]. Nature 2012
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The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary.
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David N Louis, Arie Perry, Guido Reifenberger, Andreas von Deimling, Dominique Figarella-Branger, Webster K Cavenee, Hiroko Ohgaki, Otmar D Wiestler, Paul Kleihues, David W Ellison. Acta Neuropathol 2016
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DNA methylation-based classification of central nervous system tumours.
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Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma.
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New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs.
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Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas.
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The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma.
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Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.
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Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers.
Andrey Korshunov, Marina Ryzhova, Volker Hovestadt, Sebastian Bender, Dominik Sturm, David Capper, Jochen Meyer, Daniel Schrimpf, Marcel Kool, Paul A Northcott,[...]. Acta Neuropathol 2015
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IDH1 and IDH2 mutations in gliomas.
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Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups.
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K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas.
Dong-Anh Khuong-Quang, Pawel Buczkowicz, Patricia Rakopoulos, Xiao-Yang Liu, Adam M Fontebasso, Eric Bouffet, Ute Bartels, Steffen Albrecht, Jeremy Schwartzentruber, Louis Letourneau,[...]. Acta Neuropathol 2012
Dong-Anh Khuong-Quang, Pawel Buczkowicz, Patricia Rakopoulos, Xiao-Yang Liu, Adam M Fontebasso, Eric Bouffet, Ute Bartels, Steffen Albrecht, Jeremy Schwartzentruber, Louis Letourneau,[...]. Acta Neuropathol 2012
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Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas.
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Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes.
David Castel, Cathy Philippe, Raphaël Calmon, Ludivine Le Dret, Nathalène Truffaux, Nathalie Boddaert, Mélanie Pagès, Kathryn R Taylor, Patrick Saulnier, Ludovic Lacroix,[...]. Acta Neuropathol 2015
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Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma.
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cIMPACT-NOW update 2: diagnostic clarifications for diffuse midline glioma, H3 K27M-mutant and diffuse astrocytoma/anaplastic astrocytoma, IDH-mutant.
David N Louis, Caterina Giannini, David Capper, Werner Paulus, Dominique Figarella-Branger, M Beatriz Lopes, Tracy T Batchelor, J Gregory Cairncross, Martin van den Bent, Wolfgang Wick,[...]. Acta Neuropathol 2018
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Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology.
Ibrahim Qaddoumi, Wilda Orisme, Ji Wen, Teresa Santiago, Kirti Gupta, James D Dalton, Bo Tang, Kelly Haupfear, Chandanamali Punchihewa, John Easton,[...]. Acta Neuropathol 2016
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cIMPACT-NOW update 3: recommended diagnostic criteria for "Diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma, WHO grade IV".
Daniel J Brat, Kenneth Aldape, Howard Colman, Eric C Holland, David N Louis, Robert B Jenkins, B K Kleinschmidt-DeMasters, Arie Perry, Guido Reifenberger, Roger Stupp,[...]. Acta Neuropathol 2018
Daniel J Brat, Kenneth Aldape, Howard Colman, Eric C Holland, David N Louis, Robert B Jenkins, B K Kleinschmidt-DeMasters, Arie Perry, Guido Reifenberger, Roger Stupp,[...]. Acta Neuropathol 2018
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Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations.
Annekathrin Reinhardt, Damian Stichel, Daniel Schrimpf, Felix Sahm, Andrey Korshunov, David E Reuss, Christian Koelsche, Kristin Huang, Annika K Wefers, Volker Hovestadt,[...]. Acta Neuropathol 2018
Annekathrin Reinhardt, Damian Stichel, Daniel Schrimpf, Felix Sahm, Andrey Korshunov, David E Reuss, Christian Koelsche, Kristin Huang, Annika K Wefers, Volker Hovestadt,[...]. Acta Neuropathol 2018
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Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma.
Michele Ceccarelli, Floris P Barthel, Tathiane M Malta, Thais S Sabedot, Sofie R Salama, Bradley A Murray, Olena Morozova, Yulia Newton, Amie Radenbaugh, Stefano M Pagnotta,[...]. Cell 2016
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Histone H3.3. mutations drive pediatric glioblastoma through upregulation of MYCN.
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H3.3 G34R mutations in pediatric primitive neuroectodermal tumors of central nervous system (CNS-PNET) and pediatric glioblastomas: possible diagnostic and therapeutic implications?
Marco Gessi, Gerrit H Gielen, Jennifer Hammes, Evelyn Dörner, Anja Zur Mühlen, Andreas Waha, Torsten Pietsch. J Neurooncol 2013
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Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities.
David E Reuss, Annekathrin Kratz, Felix Sahm, David Capper, Daniel Schrimpf, Christian Koelsche, Volker Hovestadt, Melanie Bewerunge-Hudler, David T W Jones, Jens Schittenhelm,[...]. Acta Neuropathol 2015
David E Reuss, Annekathrin Kratz, Felix Sahm, David Capper, Daniel Schrimpf, Christian Koelsche, Volker Hovestadt, Melanie Bewerunge-Hudler, David T W Jones, Jens Schittenhelm,[...]. Acta Neuropathol 2015
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Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma.
David T W Jones, Barbara Hutter, Natalie Jäger, Andrey Korshunov, Marcel Kool, Hans-Jörg Warnatz, Thomas Zichner, Sally R Lambert, Marina Ryzhova, Dong Anh Khuong Quang,[...]. Nat Genet 2013
David T W Jones, Barbara Hutter, Natalie Jäger, Andrey Korshunov, Marcel Kool, Hans-Jörg Warnatz, Thomas Zichner, Sally R Lambert, Marina Ryzhova, Dong Anh Khuong Quang,[...]. Nat Genet 2013
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TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal.
Patrick J Killela, Zachary J Reitman, Yuchen Jiao, Chetan Bettegowda, Nishant Agrawal, Luis A Diaz, Allan H Friedman, Henry Friedman, Gary L Gallia, Beppino C Giovanella,[...]. Proc Natl Acad Sci U S A 2013
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Diffuse Midline Gliomas with Histone H3-K27M Mutation: A Series of 47 Cases Assessing the Spectrum of Morphologic Variation and Associated Genetic Alterations.
David A Solomon, Matthew D Wood, Tarik Tihan, Andrew W Bollen, Nalin Gupta, Joanna J J Phillips, Arie Perry. Brain Pathol 2016
David A Solomon, Matthew D Wood, Tarik Tihan, Andrew W Bollen, Nalin Gupta, Joanna J J Phillips, Arie Perry. Brain Pathol 2016
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cIMPACT-NOW update 4: diffuse gliomas characterized by MYB, MYBL1, or FGFR1 alterations or BRAFV600E mutation.
David W Ellison, Cynthia Hawkins, David T W Jones, Arzu Onar-Thomas, Stefan M Pfister, Guido Reifenberger, David N Louis. Acta Neuropathol 2019
David W Ellison, Cynthia Hawkins, David T W Jones, Arzu Onar-Thomas, Stefan M Pfister, Guido Reifenberger, David N Louis. Acta Neuropathol 2019
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Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma.
Genevieve Schindler, David Capper, Jochen Meyer, Wibke Janzarik, Heymut Omran, Christel Herold-Mende, Kirsten Schmieder, Pieter Wesseling, Christian Mawrin, Martin Hasselblatt,[...]. Acta Neuropathol 2011
Genevieve Schindler, David Capper, Jochen Meyer, Wibke Janzarik, Heymut Omran, Christel Herold-Mende, Kirsten Schmieder, Pieter Wesseling, Christian Mawrin, Martin Hasselblatt,[...]. Acta Neuropathol 2011
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C11orf95-RELA fusions drive oncogenic NF-κB signalling in ependymoma.
Matthew Parker, Kumarasamypet M Mohankumar, Chandanamali Punchihewa, Ricardo Weinlich, James D Dalton, Yongjin Li, Ryan Lee, Ruth G Tatevossian, Timothy N Phoenix, Radhika Thiruvenkatam,[...]. Nature 2014
Matthew Parker, Kumarasamypet M Mohankumar, Chandanamali Punchihewa, Ricardo Weinlich, James D Dalton, Yongjin Li, Ryan Lee, Ruth G Tatevossian, Timothy N Phoenix, Radhika Thiruvenkatam,[...]. Nature 2014
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Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors.
Jeanette E Eckel-Passow, Daniel H Lachance, Annette M Molinaro, Kyle M Walsh, Paul A Decker, Hugues Sicotte, Melike Pekmezci, Terri Rice, Matt L Kosel, Ivan V Smirnov,[...]. N Engl J Med 2015
Jeanette E Eckel-Passow, Daniel H Lachance, Annette M Molinaro, Kyle M Walsh, Paul A Decker, Hugues Sicotte, Melike Pekmezci, Terri Rice, Matt L Kosel, Ivan V Smirnov,[...]. N Engl J Med 2015
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ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an "integrated" diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma.
David E Reuss, Felix Sahm, Daniel Schrimpf, Benedikt Wiestler, David Capper, Christian Koelsche, Leonille Schweizer, Andrey Korshunov, David T W Jones, Volker Hovestadt,[...]. Acta Neuropathol 2015
David E Reuss, Felix Sahm, Daniel Schrimpf, Benedikt Wiestler, David Capper, Christian Koelsche, Leonille Schweizer, Andrey Korshunov, David T W Jones, Volker Hovestadt,[...]. Acta Neuropathol 2015
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The somatic genomic landscape of glioblastoma.
Cameron W Brennan, Roel G W Verhaak, Aaron McKenna, Benito Campos, Houtan Noushmehr, Sofie R Salama, Siyuan Zheng, Debyani Chakravarty, J Zachary Sanborn, Samuel H Berman,[...]. Cell 2013
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Novel, improved grading system(s) for IDH-mutant astrocytic gliomas.
Mitsuaki Shirahata, Takahiro Ono, Damian Stichel, Daniel Schrimpf, David E Reuss, Felix Sahm, Christian Koelsche, Annika Wefers, Annekathrin Reinhardt, Kristin Huang,[...]. Acta Neuropathol 2018
Mitsuaki Shirahata, Takahiro Ono, Damian Stichel, Daniel Schrimpf, David E Reuss, Felix Sahm, Christian Koelsche, Annika Wefers, Annekathrin Reinhardt, Kristin Huang,[...]. Acta Neuropathol 2018
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Prevalence and clinicopathological features of H3.3 G34-mutant high-grade gliomas: a retrospective study of 411 consecutive glioma cases in a single institution.
Koji Yoshimoto, Ryusuke Hatae, Yuhei Sangatsuda, Satoshi O Suzuki, Nobuhiro Hata, Yojiro Akagi, Daisuke Kuga, Murata Hideki, Koji Yamashita, Osamu Togao,[...]. Brain Tumor Pathol 2017
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cIMPACT-NOW update 6: new entity and diagnostic principle recommendations of the cIMPACT-Utrecht meeting on future CNS tumor classification and grading.
David N Louis, Pieter Wesseling, Kenneth Aldape, Daniel J Brat, David Capper, Ian A Cree, Charles Eberhart, Dominique Figarella-Branger, Maryam Fouladi, Gregory N Fuller,[...]. Brain Pathol 2020
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MGMT gene silencing and benefit from temozolomide in glioblastoma.
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Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge.
Dominik Sturm, Sebastian Bender, David T W Jones, Peter Lichter, Jacques Grill, Oren Becher, Cynthia Hawkins, Jacek Majewski, Chris Jones, Joseph F Costello,[...]. Nat Rev Cancer 2014
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Molecular subgroups of medulloblastoma: the current consensus.
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Distinct Histomorphology in Molecular Subgroups of Glioblastomas in Young Patients.
Julia E Neumann, Mario M Dorostkar, Andrey Korshunov, Christian Mawrin, Arend Koch, Armin Giese, Ulrich Schüller. J Neuropathol Exp Neurol 2016
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Announcing cIMPACT-NOW: the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy.
David N Louis, Ken Aldape, Daniel J Brat, David Capper, David W Ellison, Cynthia Hawkins, Werner Paulus, Arie Perry, Guido Reifenberger, Dominique Figarella-Branger,[...]. Acta Neuropathol 2017
David N Louis, Ken Aldape, Daniel J Brat, David Capper, David W Ellison, Cynthia Hawkins, Werner Paulus, Arie Perry, Guido Reifenberger, Dominique Figarella-Branger,[...]. Acta Neuropathol 2017
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cIMPACT-NOW update 5: recommended grading criteria and terminologies for IDH-mutant astrocytomas.
Daniel J Brat, Kenneth Aldape, Howard Colman, Dominique Figrarella-Branger, Gregory N Fuller, Caterina Giannini, Eric C Holland, Robert B Jenkins, Bette Kleinschmidt-DeMasters, Takashi Komori,[...]. Acta Neuropathol 2020
Daniel J Brat, Kenneth Aldape, Howard Colman, Dominique Figrarella-Branger, Gregory N Fuller, Caterina Giannini, Eric C Holland, Robert B Jenkins, Bette Kleinschmidt-DeMasters, Takashi Komori,[...]. Acta Neuropathol 2020
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An integrated genomic analysis of human glioblastoma multiforme.
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Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas.
Sebastian Bender, Yujie Tang, Anders M Lindroth, Volker Hovestadt, David T W Jones, Marcel Kool, Marc Zapatka, Paul A Northcott, Dominik Sturm, Wei Wang,[...]. Cancer Cell 2013
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Immunohistochemical analysis of H3K27me3 demonstrates global reduction in group-A childhood posterior fossa ependymoma and is a powerful predictor of outcome.
Pooja Panwalkar, Jonathan Clark, Vijay Ramaswamy, Debra Hawes, Fusheng Yang, Christopher Dunham, Stephen Yip, Juliette Hukin, Yilun Sun, Matthew J Schipper,[...]. Acta Neuropathol 2017
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IDH mutant diffuse and anaplastic astrocytomas have similar age at presentation and little difference in survival: a grading problem for WHO.
David E Reuss, Yasin Mamatjan, Daniel Schrimpf, David Capper, Volker Hovestadt, Annekathrin Kratz, Felix Sahm, Christian Koelsche, Andrey Korshunov, Adriana Olar,[...]. Acta Neuropathol 2015
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Epithelioid GBMs show a high percentage of BRAF V600E mutation.
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Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1.
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Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma.
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H3-/IDH-wild type pediatric glioblastoma is comprised of molecularly and prognostically distinct subtypes with associated oncogenic drivers.
Andrey Korshunov, Daniel Schrimpf, Marina Ryzhova, Dominik Sturm, Lukas Chavez, Volker Hovestadt, Tanvi Sharma, Antje Habel, Anna Burford, Chris Jones,[...]. Acta Neuropathol 2017
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.